Cover design: Jola Glotzer

51st Annual Drosophila Research Conference April 7–11, 2010 Marriott Wardman Park Washington, DC

Program 

2010 Meeting Organizers Debbie Andrew, Johns Hopkins School of Medicine Mark Fortini, Thomas Jefferson University Steve Hou, National Institutes of Health Leslie Pick, University of Maryland



2009/2010 Drosophila Board of Directors Officers President President-Elect Past-President Past-President Past-President & Elections Chair Treasurer

Terry Orr-Weaver Denise Montell Carl Thummel Trudy MacKay

Whitehead Institute for Biomedical Research, MIT Johns Hopkins School of Medicine University of Utah North Carolina State

Utpal Banerjee Pam Geyer

University of California, Los Angeles University of Iowa

Regional Representatives Canada Great Lakes Northwest Southeast California Heartland New England Mid-Atlantic Midwest 

Mount Sinai Hospital Carnegie-Mellon University University of Washington University of North Carolina University of California, San Francisco The University of Texas at Austin Brandeis University Princeton University University of Minnesota

International Representatives Australia/Oceana Asia Europe



Helen McNeil A. Javier Lopez Hannele Ruohola-Baker Jeff Sekelsky Graeme Davis Janice Fischer Leslie Griffith Liz Gavis Tom Neufeld

Phil Batterham Vijay Raghavan Barry Dickson

University of Melbourne The National Centre for Biological Sciences Research Institute of Molecular Pathology

Sponsored by The Genetics Society of America 9650 Rockville Pike, Bethesda, MD 20814-3998 Telephone: 301/634-7300 fax: 301/634-7079 E-mail: [email protected] Web site: http://www.genetics-gsa.org/ Conference site: http://www.drosophila-conf.org/

TABLE OF CONTENTS

3

Schedule of Events ....................................................................................................................................................... 4 Map: Marriott Wardman Park Meeting/Exhibit Space ............................................................................................... 11 General Information .................................................................................................................................................... 14 Speaker Presentation Guidelines .............................................................................................................................. 17 Larry Sandler Memorial Lecture................................................................................................................................. 19 The DeLill Nasser Award for Professional Development in Genetics .................................................................... 19 Poster Award Competition.......................................................................................................................................... 20 Sponsor and Exhibitors .............................................................................................................................................. 21 Floorplan: Posters and Exhibits................................................................................................................................. 24 Opening General Session and Plenary Sessions I and II ........................................................................................ 25 Workshops ................................................................................................................................................................... 26 Concurrent Platform Sessions................................................................................................................................... 30 Poster Sessions........................................................................................................................................................... 44 Speaker and Author Index .......................................................................................................................................... 81 Keyword Index ............................................................................................................................................................. 96 FlyBase Genetic Index to Abstracts ........................................................................................................................ 102

FUTURE MEETING DATES 2011 March 30-April 3 San Diego, CA

2014 April 9-13 San Diego, CA

2012 March 7-11 Chicago, IL

2015 March 4-8 Chicago, IL

2013 April 3-7 Washington, DC

2016 March 2-6 Philadelphia, PA

4

SCHEDULE OF EVENTS 51st Annual Drosophila Research Conference

WEDNESDAY, APRIL 7 12:00 noon - 6:00 pm Ecdysone Workshop Organizers: Deborah Hoshizaki, University of Nevada, Las Vegas; and Christen Mirth, Janelia Farm Research Campus, HHMI

Washington 2 Hall B North Exhibition Level

3:00 pm - 6:30 pm Speaker Ready Room All speakers must upload their presentations in this room at least four hours before the start of the program in which they are presenting

Park Tower Suite 8216 Lobby Level

3:30 pm - 9:00 pm Registration and Book/T-Shirt Pickup Open

Convention Registration Desk Lobby Level

7:00 pm - 9:15 pm Opening General Session Moderators: Leslie Pick, University of Maryland, College Park; and Mark Fortini, Thomas Jefferson University, Philadelphia, Pennsylvania

Marriott Ballroom Salons 1-3 Lobby Level

7:00 pm Welcome and Opening Remarks Leslie Pick, University of Maryland, College Park 7:10 pm GSA Executive Director Sherry Marts, The Genetics Society of America, Bethesda, Maryland 7:15 pm Introduction of Larry Sandler Lecture Janice Fischer, University of Texas, Austin 7:20 pm Larry Sandler Lecture 7:50 pm Historical Panel Viewpoints Featuring Thom Kaufman, Gerald M. Rubin, Susan E. Celniker, William M. Gelbart, Allan C. Spradling and Norbert Perrimon Hugo Bellen, Baylor College of Medicine, Houston, Texas 9:00 pm - 12:00 am Mixer/Reception

Washington 4-6 Hall B North Exhibition Level

THURSDAY, APRIL 8 7:00 am - 3:00 pm Speaker Ready Room Park Tower Suite All speakers must upload their presentations in this room at least four 8216 Lobby Level hours before the start of the program in which they are presenting 7:15 am - 8:30 am Continental Breakfast

Marriott Ballroom Foyer Lobby Level

8:00 am - 5:00 pm Registration and Book/T-Shirt Pickup Open

Convention Registration Desk Lobby Level

SCHEDULE OF EVENTS 51st Annual Drosophila Research Conference

8:30 am - 12:00 noon Plenary Session I Moderator: Steven Hou, NIH, Frederick, Maryland

5

Marriott Ballroom Salons 1-3 Lobby Level

8:30 am Image Award Presentation Brian Calvi, Indiana University, Bloomington 8:35 am Control of Organ Size and Tumorigenesis by the Hippo Signaling Pathway Duojia (DJ) Pan, Johns Hopkins University School of Medicine, Baltimore, Maryland 9:00 am Growth Control by the Fat-Hippo Pathway in Drosophila Kenneth D. Irvine, Waksman Institute, Rutgers University, Piscataway, New Jersey 9:30 am Cell Polarity - Understanding Pattern Formation at the Cellular Level Elisabeth Knust, Max Planck Institute of Molecular Cell Biology & Genetics, Dresden, Germany 10:00 am Break Sponsored by Genetic Services, Inc. (booth 104) 10:30 am Molecular and Cellular Mechanisms Underlying Ovarian Germline Stem Cell Regulation Ting Xie, Stowers Institute, Kansas City, Missouri 11:00 am Regulation and Function of Autophagy During Cell Survival and Cell Death Eric H. Baehrecke, University of Massachusetts Medical School, Worcester 11:30 am Cellular Mechanisms Controlling Oocyte Growth Lynn Cooley, Department of Genetics and Department of Cell Biology, Yale School of Medicine; Department of MCDB, Yale University, New Haven, CT 1:00 pm - 4:00 pm FlyBase Demo Room Open for Tutorials and Discussions Presentations: 2:30-2:50 pm: Getting the Most out of FlyBase 3:00-3:20 pm: Mining Genomes - Tools of the Trade

Delaware Lobby Level

1:00 pm - 6:00 pm FlyMine Demonstrations Presentations: 1:30 pm-1:50 pm: FlyMine 2:00 pm-2:20 pm: modENCODE

Virginia A-B Lobby Level

4:00 pm-4:20 pm: FlyMine 4:30 pm-4:50 pm: modENCODE 2:00 pm - 4:00 pm Exhibits Open & Poster Presentations 2:00 pm-3:00 pm: Even-Numbered Poster Authors 3:00 pm-4:00 pm: Odd-Numbered Poster Authors

Exhibit Hall B South/C Exhibition Level

Poster Viewing Open 24 Hours 3:30 pm - 4:30 pm “Meet the Board” Reception Atrium Open to all attendees. Come meet members of the Drosophila Board Exhibition Level and receive a ticket for a complimentary beverage.

6

SCHEDULE OF EVENTS 51st Annual Drosophila Research Conference

4:30 pm - 6:30 pm Concurrent Platform Sessions Cell Biology & Signal Transduction

Marriott Ballroom Salon 2 Lobby Level

Evolution & Quantitative Genetics I

Marriott Ballroom Salon 1 Lobby Level

Physiology & Aging

Marriott Ballroom Salon 3 Lobby Level

8:00 pm - 11:00 pm Exhibits Open and Poster Viewing

Exhibit Hall B South/C Exhibition Level

FRIDAY, APRIL 9 7:00 am - 3:00 pm Speaker Ready Room All speakers must upload their presentations in this room at least four hours before the start of the program in which they are presenting

Park Tower Suite 8216 Lobby Level

8:30 am - 10:15 am Concurrent Platform Sessions Cell Biology and Cytoskeleton

Marriott Ballroom Salon 2 Lobby Level

Evolution and Quantitative Genetics II

Marriott Ballroom Salon 1 Lobby Level

Neurogenetics and Neural Development

Marriott Ballroom Salon 3 Lobby Level

8:30 am - 5:00 pm Registration and Book/T-Shirt Pickup Open

Convention Registration Desk Lobby Level

9:00 am - 6:00 pm FlyMine Demonstrations Presentations: 1:30 pm-1:50 pm: FlyMine 2:00 pm-2:20 pm: modENCODE

Virginia A-B Lobby Level

4:00 pm-4:20 pm: FlyMine 4:30 pm-4:50 pm: modENCODE 10:15 am - 10:45 am Refreshment Break

Marriott Ballroom Foyer Lobby Level

SCHEDULE OF EVENTS 51st Annual Drosophila Research Conference

7

10:45 am - 12:30 pm Concurrent Platform Sessions Gametogenesis and Organogenesis I

Marriott Ballroom Salon 2 Lobby Level

Regulation of Gene Expression

Marriott Ballroom Salon 1 Lobby Level

Cell Division and Growth Control

Marriott Ballroom Salon 3 Lobby Level

12:30 pm - 1:45 pm GSA Mentor Roundtable Luncheon 1:00 pm - 4:00 pm FlyBase Demo Room Open for Tutorials and Discussions Presentations: 2:30 pm-2:50 pm: Getting the Most out of FlyBase 3:00 pm-3:20 pm: Mining Genomes - Tools of the Trade

Washington Room 2 Exhibition Level Delaware Lobby Level

1:45 pm - 3:45 pm Concurrent Workshops Marriott Ballroom The modENCODE Project Organizers: Susan Celniker, Lawrence Berkeley National Laboratory; Salon 2 Gary Karpen, Lawrence Berkeley National Laboratory; Artyom Kopp, Lobby Level University of California, Davis; Kevin White, University of Chicago and Argonne National Laboratory; and David MacAlpine, Duke University Medical Center Chemical Genetics and Drug Screening in Drosophila Organizer: Tin Tin Su, University of Colorado, Boulder

Virginia Suite C Lobby Level

RNAi Screening in Cells and Flies Organizers: Stephanie Mohr, Harvard Medical School, Cambridge, Massachusetts; Michael Boutros, German Cancer Research Center; Krystyna Keleman, Institute of Molecular Pathology; and Liz Perkins, Massachusetts General Hospital & HMS

Marriott Ballroom Salon 1 Lobby Level

Drosophotoxicology: The Growing Potential for Flies in Toxicology Research Organizer: Matthew Rand, University of Vermont

Marriott Ballroom Salon 3 Lobby Level

2:00 pm - 4:00 pm Dedicated Exhibit Time and Open Poster Vewing

Exhibit Hall B South/C Exhibition Level

4:30 pm - 6:30 pm Concurrent Platform Sessions Gametogenesis and Organogenesis II

Marriott Ballroom Salon 2 Lobby Level

Techniques and Functional Genomics I

Marriott Ballroom Salon 1 Lobby Level

8

SCHEDULE OF EVENTS 51st Annual Drosophila Research Conference

Chromatin and Epigenetics

8:00 pm - 11:00 pm Exhibits Open and Poster Presentations 8:00 pm-9:00 pm: “C” Poster Authors 9:00 pm-10:00 pm: “B” Poster Authors 10:00 pm-11:00 pm: “A” Poster Authors

Marriott Ballroom Salon 3 Lobby Level Exhibit Hall B South/C Exhibition Level

Poster Viewing Open 24 Hours SATURDAY, APRIL 10 7:00 am - 3:00 pm Speaker Ready Room All speakers must upload their presentations in this room at least four hours before the start of the program in which they are presenting

Park Tower Suite 8216 Lobby Level

8:30 am - 10:15 am Concurrent Platform Sessions Drosophila Models of Human Disease I

Marriott Ballroom Salon 2 Lobby Level

Stem Cells

Marriott Ballroom Salon 1 Lobby Level

Pattern Formation

Marriott Ballroom Salon 3 Lobby Level

8:30 am - 3:00 pm Registration and Book/T-Shirt Pickup Open

Convention Registration Desk Lobby Level

9:00 am - 6:00 pm FlyMine Demonstrations Presentations: 1:30 pm-1:50 pm: FlyMine 2:00 pm-2:20 pm: modENCODE

Virginia A-B Lobby Level

4:00 pm-4:20 pm: FlyMine 4:30 pm-4:50 pm: modENCODE 10:15 am - 10:45 am Refreshment Break

Marriott Ballroom Foyer Lobby Level

10:45 am - 12:30 pm Concurrent Platform Sessions Drosophila Models of Human Disease II

Marriott Ballroom Salon 2 Lobby Level

Techniques and Functional Genomics II

Marriott Ballroom Salon 1 Lobby Level

SCHEDULE OF EVENTS 51st Annual Drosophila Research Conference

RNA Biology

12:30 pm - 2:00 pm Government Affairs Update Sign up by 5:00 pm, Friday, April 9, at the Convention Registration Desk. Limited Attendance 1:30 pm - 3:30 pm Exhibits Open and Poster Presentations 1:30 pm-2:30 pm: Odd-Numbered Poster Authors 2:30 pm-3:30 pm: Even-Numbered Poster Authors

9

Marriott Ballroom Salon 3 Lobby Level Convention Registration Desk Lobby Level Exhibit Hall B South/C Exhibition Level

Poster Viewing Open 24 Hours 4:00 pm - 6:00 pm Concurrent Platform Sessions Cell Cycle and Cell Death

Marriott Ballroom Salon 2 Lobby Level

Neural Physiology and Behavior

Marriott Ballroom Salon 1 Lobby Level

Immunity and Pathogenesis

Marriott Ballroom Salon 3 Lobby Level

6:45 pm - 8:45 pm Concurrent Workshops Everything You Ever Wanted to Know About Sex Organizers: Michelle Arbeitman, University of Southern California, Los Angeles; Artyom Kopp, University of California, Davis; Mark Siegal, NYU; and Mark Van Doren, Johns Hopkins

Marriott Ballroom Salon 3 Lobby Level

Apoptosis, Autophagy and Other Cell Death Mechanisms Organizers: Andreas Bergmann, MD Anderson Cancer Center; Eli Arama, Weizmann Institute, Israel; Janet Rollins, Mount Saint Vincent College, Riverdale, New York; Don W. Paetkau, Saint Mary’s College, Notre Dame, Indiana; and Michael Brodsky, University of Massachusetts Medical School

Marriott Ballroom Salon 2 Lobby Level

Drosophila Research and Pedagogy at Primarily Undergraduate Institutions (PUI) Organizers: Alexis Nagengast, Widener University, Chester, Pennsylvania; Janet Rollins, College of Mount Saint Vincent, Riverdale, New York; and Thomas Onorato, LaGuardia Community College

Virginia Suite C Lobby Level

Image Analysis for Drosophila Research Organizers: Pavel Tomancak, MPI-CBG, Dresden; and Uwe Ohler, Duke University, Durham, North Carolina

Marriott Ballroom Salon 1 Lobby Level

7:00 pm - 10:00 pm Exhibits Open and Poster Viewing

Exhibit Hall B South/C Exhibition Level

10

SCHEDULE OF EVENTS 51st Annual Drosophila Research Conference

9:30 pm - 11:30 pm Concurrent Workshops Developmental Regulation of Cell Proliferation Organizer: Wu-Min Deng, Florida State University, Tallahassee, Florida

Virginia Suite C Lobby Level

Insect Evodevo Organizer: Markus Friedrich, Wayne State University, Detroit, Michigan

Marriott Ballroom Salon 1 Lobby Level

Automated Tracking of Drosophila Behavior Organizers: Tim Lebestky, California Institute of Technology, Pasadena, California; Andrew Straw, California Institute of Technology, Pasadena, California; and Kristin Branson, Janelia Farm Research Campus (HHMI)

Marriott Ballroom Salon 2 Lobby Level

Gases in Drosophila Physiology and Development Organizers: Dan Zhou, University of California, San Diego; and Greg Beitel, Northwestern University, Evanston, Illinois

Marriott Ballroom Salon 3 Lobby Level

SUNDAY, APRIL 11 6:00 am - 12:00 noon Speaker Ready Room All speakers must upload their presentations in this room at least four hours before the start of the program in which they are presenting

Park Tower Suite 8216 Lobby Level

8:30 am - 12:00 noon Plenary Session II Moderator: Deborah Andrew, Johns Hopkins University School of Medicine, Baltimore, Maryland

Marriott Ballroom Salons 1-3 Lobby Level

8:30 am Poster Award Presentation Mark Fortini, Thomas Jefferson University, Philadelphia, Pennsylvania 8:35 am TRP Channels: From Sensory Signaling to Neurodegenerative Disease Craig Montell, Johns Hopkins University School of Medicine, Baltimore, Maryland 9:00 am The Role of Dscam Proteins in Regulating Neural Circuit Assembly in Drosophila Larry Zipursky, UCLA/HHMI, Los Angeles, California 9:30 am Sleep and Synaptic Plasticity Chiara Cirelli, Department of Psychiatry, University of Wisconsin, Madison 10:00 am Tribute to Dr. John Sisson Bill Sullivan, University of California, Santa Cruz 10:05 am Break 10:30 am The Process of Myoblast Fusion in Skeletal Muscle Cells Elizabeth Chen, Johns Hopkins University School of Medicine, Baltimore, Maryland 11:00 am Microtubule Motors and the Oocyte Spindle Sharyn Endow, Duke University Medical Center, Durham, North Carolina 11:30 am How We Study the Evolution of Novel Complex Traits Antonia Monteiro, Yale University, New Haven, Connecticut

SPEAKER READY ROOM

MARRIOTT WARDMAN PARK HOTEL

11

MARRIOTT WARDMAN PARK HOTEL

(Poster Pickup)

12

13

ENTRANCE TO EXHIBITION HALL

MARRIOTT WARDMAN PARK HOTEL

14

GENERAL INFORMATION

 Badges Badges are required for admission to all sessions, the opening mixer, and the posters and exhibits in the Exhibition Hall. Security officers will not allow individuals without badges to enter the Exhibition Hall. If you lose your badge, a replacement may be requested at the Registration and Information Counters during posted registration hours. Badges may not be used by anyone other than the registered attendee. Each attendee must have his/her own badge.  Employment Opportunities/Seeking Employment Notices – Convention Registration Desk Individuals and institutions offering or seeking employment may post notices and résumés on the “Employment Opportunities” bulletin boards set up near the Registration and Information Counters on the lobby level at the Convention Registration Desk. Be sure to stop by the Convention Registration Desk and ask about the new Career Center now online at www.genetics-gsa.org  FlyBase Demonstrations – Delaware, Lobby Level FlyBase invites all Conference registrants to come to the demo room to learn how to make the best use of the new FlyBase tools and features for your research and teaching. Throughout the day, other than the scheduled group presentations noted below, FlyBase personnel are available in the demo room for one-on-one tutorials, troubleshooting and discussions. Any thoughts on improvements we can make to FlyBase are gratefully appreciated. Thursday, April 8

1:00 pm-4:00 pm

Demo room open for tutorials and discussions Presentations: 2:30 pm-2:50 pm: Getting the Most out of FlyBase 3:00 pm-3:20 pm: Mining Genomes – Tools of the Trade

Friday, April 9

1:00 pm-4:00 pm

Demo room open for tutorials and discussions Presentations: 2:30 pm-2:50 pm: Getting the Most out of FlyBase 3:00 pm-3:20 pm: Mining Genomes – Tools of the Trade

 FlyMine and modENCODE Demonstrations – Virginia A-B FlyMine is an integrated database of genomics and proteomics data for Drosophila and other insects. modENCODE (model organism ENCyclopedia Of DNA Elements) is a project designed to identify all of the sequence-based functional elements in D. melanogaster and C. elegans. The modMine database uses the same underlying software as FlyMine (InterMine) to provide a query interface to data from the modENCODE project. Come and see us to find out how you can easily run a range of diverse queries across these databases, construct your own data mining queries, upload and analyze your own experimental results and view and download large datasets from the modENCODE project. Talks will take place daily, Thursday through Saturday, at the following times: 1:30 pm-1:50 pm: FlyMine 2:00 pm-2:20 pm: modENCODE 4:00 pm-4:20 pm: 4:30pm-4:50 pm:

FlyMine modENCODE

 Government Affairs Update On Saturday, April 10, from 12:30 pm until 2:00 pm, staff members from the FASEB Office of Public Affairs will discuss the latest policy and legislative news, and describe the many ways scientists can get involved with issues that affect their grants and research. Sign up at the registration desk by Friday, April 9, at 5:00 pm. Limited attendance.  GSA Mentor Roundtable – Washington 2, Exhibition Level (escalators by Registration Desk) This session will be held on Friday, April 9, from 12:30 pm until 1:45 pm. Principal investigators will be available to discuss their work and give valuable advice and input on career opportunities. For interested graduate and post docs. Fee. Limited attendance.  Internet Access – Hotel Lobby Complimentary high speed Internet access is available in the lounge area next to the lobby.

GENERAL INFORMATION

15

 Meals Please note that two meals are included in the meeting registration: the Opening Mixer on Wednesday night (with heavy hors d’oeuvres and a cash bar) and the Continental Breakfast on Thursday morning. All other meals are not included in your Conference registration. For all other meals you may choose from options within the hotel or visit the many restaurants in Woodley Park. You’ll find everything from McDonalds and Chipotle to five star dining. Just stop by the Registration Desk for a map of the area or see the concierge in the hotel lobby for more detailed information and suggestions.  Message Boards – Convention Registration Area Message boards will be located near the Registration and Information Counters.  Parking The hotel offers both valet (currently $37 daily) and self-park (currently $17 for up to two hours and $28 for 2-24 hours). Washington, DC, is a very “walkable” city and the Metro system, with a stop right out the front door of the Conference hotel, is easy to navigate, so a car is generally not needed. Stop by the Convention Registration Desk for a Metro map.  Poster Sessions and Exhibits – Exhibition Hall All posters will be displayed in the Exhibition Hall. The Hall will be open to Conference registrants on a 24-hour basis beginning at 5:00 pm, Wednesday, April 7, until 10:00 pm, Saturday, April 10. Security will be posted at the entrance to the Hall and only individuals with official Drosophila Conference registration badges will be admitted. All attendees are responsible for their own personal items and should not leave things unattended. Guest pass applications may be made at the registration counter during regular registration hours. Exhibit representatives will be in their booths: Thursday, April 8: 2:00 pm-4:00 pm and 8:00 pm-11:00 pm Friday, April 9: 2:00 pm-4:00 pm and 8:00 pm-11:00 pm Saturday, April 10: 1:30 pm-3:30 pm and 7:00 pm-10:00 pm Authors are expected to be present at their boards according to the following schedule: Thursday, April 8: 2:00 pm-3:00 pm Even-Numbered Posters 3:00 pm-4:00 pm Odd-Numbered Posters 8:00 pm-11:00 pm Open poster viewing (Authors not required to be present) Friday, April 9

2:00 pm-4:00 pm 8:00 pm-9:00 pm 9:00 pm-10:00 pm 10:00 pm-11:00 pm

Open poster viewing (Authors not required to be present) “C” posters “B” posters “A” posters

Saturday, April 10:

1:30 pm-2:30 pm 2:30 pm-3:30 pm 7:00 pm-10:00 pm

Odd-Numbered Posters Even-Numbered Posters Open poster viewing (Authors not required to be present)

All posters must be removed from poster boards no later than 11:00 pm on Saturday, April 10. After that time, remaining posters will be removed by vendors and may be lost or thrown away. The GSA Administrative Office does not take responsibility for posters that are not removed by 11:00 pm on Saturday.  Registration, Book and T-Shirt Pickup – Convention Registration Desk Conference registration and book pickup will be open as follows: Wednesday, April 7 3:30 pm-9:00 pm Thursday, April 8 8:00 am-5:00 pm Friday, April 9 8:30 am-5:00 pm Saturday, April 10 8:30 am-3:00 pm Note that attendees must be registered before attending the Opening General Session on Wednesday, April 7, 7:00 pm, in order to attend that session. Those who purchased t-shirts can pick them up at any time during normal registration hours but BEFORE noon on April 10. A limited number of additional t-shirts have been ordered and will be available for sale on site.

16

GENERAL INFORMATION

 Speaker Ready Room – Park Tower, Suite 8216 All speakers are required to load and check their presentation at least four hours (preferably the day before) in advance of the start of the session (i.e., not your specific time slot but the overall session start time) in the Speaker Ready Room. The Speaker Ready Room will be open according to the following schedule: Wednesday, April 7 Thursday, April 8 Friday, April 9 Saturday, April 10

3:00 pm-6:30 pm 7:00 am-3:00 pm 7:00 am-3:00 pm 7:00 am-3:00 pm

IMPORTANT – Even if you have loaded your presentation before the Conference you still must check in at the Speaker Ready Room. Presentations cannot be loaded in the meeting rooms.

SPEAKER PRESENTATION GUIDELINES

17

The computers in the session rooms will be Windows XP based PC with Microsoft PowerPoint 2007. Verification of proper performance in the Speaker Ready Room (Park Tower, Suite 8216) is essential, particularly if video and animation is included in the presentation. Please note that Internet access will not be available during your presentation.  Preparing Your Presentation New This Year: Speakers will receive an e-mail from PSAV that will include a link and individual login credentials to submit their presentations online prior to the start of the meeting. Acceptable formats for presentations: s0OWER0OINTPPT PPTX s!DOBE!CROBATPDF s&LASHSWF Macintosh Users: Please make sure that all inserted pictures are either JPEG or PNG file-types. QuickTime (.mov) files are also an accepted video format. Individuals using Apple Keynote should take their files directly to the Speaker Ready Room to have them correctly transferred to our system. Laptops: Personal laptops cannot be used in the session rooms. You must load your files via the Speaker Ready Room. However, support is available in the Speaker Ready Room for file transfers from your laptop. You should still bring a backup of the presentation on alternate media (see list of acceptable formats above). Please make sure you have all power, video, and networking adapters with you.  During Your Presentation Each session room will be staffed with an AV technician who will assist in starting each presentation. Once the presentation is launched, the presenter will control the program from the podium using a computer mouse or the up/ down/right/left keys on a keyboard.  How to Submit Your Presentation Advance Submission: Presenters will be able to submit their files via the Web and will receive their login credentials via e-mail. Online submission of your presentation files via Internet is not required, but is strongly encouraged. Presenters who send in their presentation files via the Web site will have faster check in at the Speaker Ready Room. Please make sure to upload all media files required for your presentation. Any videos, sounds, or fonts not included in your online upload folder will cause your presentation to fail in the meeting room. On-site Submission: Check in at the Speaker Ready Room preferably the day before your session to submit your files and to preview your presentation. If checking in on the day of your session, please come by at least 4 hours prior to the start of your session (note: this refers to the session start time, not the presentation start time). The PSAV technicians will assist with the upload of your files and provide the opportunity to preview and/or edit the presentation as necessary. Take a Backup: Be sure to take a backup copy of your presentation with you to the meeting. If you plan to upload files on site, bring two copies.  Speaker Ready Room – Park Tower Suite 8216 All speakers are required to load and check their presentation at least four hours (preferably the day before) in advance of the start of the session (i.e., not your specific time slot but the overall session start time) in the Speaker Ready Room. The Speaker Ready Room will be open according to the following schedule: Wednesday, April 7

3:00 pm–6:30 pm

Thursday, April 8

7:00 am–3:00 pm

Friday, April 9

7:00 am–3:00 pm

Saturday, April 10

7:00 am–3:00 pm

IMPORTANT - Even if you have loaded your presentation before the Conference you still must check in at the Speaker Ready Room. Presentations cannot be loaded in the meeting rooms. When reviewing your presentation in the Speaker Ready Room, make sure all fonts, images, and animations appear as expected and that all audio or video clips are working properly. The computers in the meeting rooms are the same as the computers in the Speaker Ready Room, therefore:

18

SPEAKER PRESENTATION GUIDELINES

IF THE PRESENTATION DOES NOT PLAY CORRECTLY IN THE SPEAKER READY ROOM, IT WILL NOT PLAY CORRECTLY IN THE MEETING ROOM.  Security u Presenters are required to provide identification in order to submit their presentation as well as to access it in the Speaker Ready Room. u Cameras and video equipment are not permitted in the Speaker Ready Room. u All files are deleted at the end of the Conference, unless permission has been granted to the Conference association to retain the presentation files.  PowerPoint Tips Video Formats: The recommended video format for Windows-based presentations is Windows Media (.wmv). For more detailed information regarding fonts, sound, video, and general compatibility, refer to http://office.microsoft.com/en-us/ powerpoint/FX100648971033.aspx. Using one of the codec’s from the following list will ensure proper performance: Microsoft - RLE, Video1, Windows Media Series 8 and 9 Divx 3/4/5 Intel Indeo Video 10 years experience in DNA sequencing, we are well-equipped to handle sequencing projects of all complexities.

 Landes Bioscience 114 1002 West Avenue Austin, TX 78701 Phone: 512/679-6050 Fax: 512/637-6079 E-mail: [email protected] URL: www.landesbioscience.com Fly is the first international peer-reviewed journal to focus exclusively on Drosophila research. Fly is abstracted/ indexed in: Medline/PubMed, Science Citation Index Expanded (available as Current Contents/Life Sciences, Zoological Record, Biological Abstract and Biosis Previews). We welcome submissions in all areas of Drosophila biology in a variety of formats.  Leica Microsystems 2345 Waukegan Bannockburn, IL 60015 Phone: 847/405-0123 800/248-0123 Fax: 847/405-0164 E-mail: [email protected] URL: www.leica-microsystems.com

106/107

Leica Microsystems will display imaging solutions designed to improve research. The world’s most powerful stereofluorescence microscope will be on display, the Leica M205 FA, which conducts time lapse, image overlay, and movie making. The Leica M205 is uiniquely designed with Fusion Optics, which allows high resolution and high depth of field imaging simultaneously, over the entire zoom range. Leica will also show the Leica SP E ‘personal’ confocal microscope.  Parter Medical Products 17015 Kingsview Ave. Carson, CA 90746 Phone: 610/972-5901 Fax: 310/327-8601 E-mail: [email protected] URL: www.partermedical.com

108

Parter Medical is the leading manufacturer of high quality plasticware for Drosophila research. Our disposable/ reusable vials and bottles are made in a wide selection of sizes, materials, and packaging choices. All of our products are manufactured for optimum durability and offer excellent value. Stop by and see why our fresh ideas lead to great Drosophila products.

SPONSOR AND EXHIBITORS  Percival Scientific, Inc. 505 Research Drive Perry, IA 50220 Phone: 515/205-9701 Fax: 515/465-9464 E-mail: [email protected] URL: www.percival-scientific.com

118

Percival Scientific, Inc. continues to set the standard of excellence for the environmental control industry, producing over 70 different models of growth chambers, special application chambers, low temperature chambers, environmental rooms and biological incubators.  Roboz Surgical Instrument Company P O Box 10710 Gaithersburg, MD 20898 Phone: 800/424-2984 x926 Fax: 888/424-3121 E-mail: [email protected] URL: www.roboz.com

102

Roboz Surgical Instrument Company is the leading name for high quality microdissecting instruments and related biomedical research products. Our catalog includes our new selection of tungsten and stainless steel microdissecting needles and minutien pins, our magnifying surgical loupes, microdissecting scissors and forceps, instrument care and handling products, and much more.  Sable Systems International 6000 S. Eastern Ave. Bldg 1 Las Vegas, NV 89119 Phone: 702/269-4445 Fax: 702/269-4446 E-mail: [email protected] URL: www.sablesys.com

103

Sable Systems International is the widely cited, international standard in high resolution metabolic screening and calorimetry. Our systems can measure Drosophila gas exchange in real time. Technical support is by published experts in insect respirometry. Please drop by our booth and discuss what we can do for your research.

 Union Biometrica 84 October Hill Road Holliston, MA 1746 Phone: 508/893-3115 Fax: 508/893-8044 E-mail: [email protected] URL: www.unionbio.com

23 115

Union Biometrica produces large-bore flow cytometers which automate the analysis, sorting and dispensing of objects too big for common cytometers, using parameters including size, and flourescent labesl. These objects include small model organism, large cells and cell clusters, combinatorial chemistry beads - virtually any object between 20-1500pm. We deliver high throughput with increased accuracy and reproducibility.  University of Maryland Insect Transformation Facility 9600 Gudelsky Dr Rockville, MD 20850 Phone: 240/314-6331 Fax: 240/314-6255 E-mail: [email protected] URL: www.umbi.umd.edu/itf-cbr

112

The University of Maryland’s Insect Transformation Facility specializes in transforming non-model insects. Services include ”fee for service” transformation (with established protocols), collaboration (to develop new protocols), training (microinjection, insect rearing) and consultation. The facility has a staff with broad and deep experience in insect biology and transformation technologies.

Marriott Wardman Park Hotel Exhibition Hall Washington, DC

24 FLOORPLAN: POSTERS AND EXHIBITS

OPENING GENERAL SESSION AND PLENARY SESSIONS I AND II 

WEDNESDAY, APRIL 7 7:00 pm–9:15 pm

Opening General Session Room: Marriott Ballroom Salons 1-3 Co-Moderators: Leslie Pick, University of Maryland, College Park and Mark Fortini, Thomas Jefferson University, Philadelphia, Pennsylvania

11:00 am

Regulation and Function of Autophagy During Cell Survival and Cell Death. Eric H. Baehrecke. University of Massachusetts Medical School, Worcester.

11:30 am

Cellular Mechanisms Controlling Oocyte Growth. Lynn Cooley. Department of Genetics and Department of Cell Biology, Yale School of Medicine; Department of MCDB, Yale University, New Haven, CT.

Presentations: 7:00 pm

Welcome and Opening Remarks. Leslie Pick. University of Maryland, College Park.

7:10 pm

GSA Executive Director. Sherry Marts. The Genetics Society of America, Bethesda, Maryland.

7:15 pm

Introduction of Larry Sandler Lecture. Janice Fischer. University of Texas, Austin.

7:20 pm

Larry Sandler Lecture.

7:50 pm

Historical Panel Viewpoints Featuring Thom Kaufman, Gerald M. Rubin, Susan E. Celniker, William M. Gelbart, Allan C. Spradling and Norbert Perrimon. Hugo Bellen. Baylor College of Medicine, Houston, Texas.



THURSDAY, APRIL 8 8:30 am–12:00 noon



SUNDAY, APRIL 11 8:30 AM–12:00 NOON

Plenary Session II Room: Marriott Ballroom Salons 1-3 Moderator: Deborah Andrew, Johns Hopkins University School of Medicine, Baltimore, Maryland Presentations: 8:30 am

Poster Award Presentation. Mark Fortini. Thomas Jefferson University, Philadelphia, Pennsylvania.

8:35 am

TRP Channels: From Sensory Signaling to Neurodegenerative Disease. Craig Montell. Johns Hopkins University School of Medicine, Baltimore, Maryland.

9:00 am

The Role of Dscam Proteins in Regulating Neural Circuit Assembly in Drosophila. Larry Zipursky. UCLA/HHMI, Los Angeles, California.

9:30 am

Sleep and Synaptic Plasticity. Chiara Cirelli. Department of Psychiatry, University of Wisconsin, Madison.

10:00 pm

Tribute to Dr. John Sisson. Bill Sullivan. University of California, Santa Cruz.

10:05 am

Break

10:30 am

The Process of Myoblast Fusion in Skeletal Muscle Cells. Elizabeth Chen. Johns Hopkins University School of Medicine, Baltimore, Maryland.

11:00 am

Microtubule Motors and the Oocyte Spindle. Sharyn Endow. Duke University Medical Center, Durham, North Carolina.

11:30 am

How We Study the Evolution of Novel Complex Traits. Antonia Monteiro. Yale University, New Haven, Connecticut.

Plenary Session I Room: Marriott Ballroom Salons 1-3 Moderator: Steven Hou, NIH, Frederick, Maryland Presentations: 8:30 am

Image Award Presentation. Brian Calvi. Indiana University, Bloomington.

8:35 am

Control of Organ Size and Tumorigenesis by the Hippo Signaling Pathway. Duojia (DJ) Pan. Johns Hopkins University School of Medicine, Baltimore, Maryland.

9:00 am

Growth Control by the Fat-Hippo Pathway in Drosophila. Kenneth D. Irvine. Waksman Inst., Rutgers University, Piscataway, New Jersey.

9:30 am

Cell Polarity - Understanding Pattern Formation at the Cellular Level. Elisabeth Knust. Max Planck Institute of Molecular Cell Biology & Genetics, Dresden, Germany.

10:00 am

Break Sponsored by Genetic Services, Inc. (booth 104)

10:30 am

Molecular and Cellular Mechanisms Underlying Ovarian Germline Stem Cell Regulation. Ting Xie. Stowers Institute, Kansas City, Missouri.

25

26 

WORKSHOPS WEDNESDAY, APRIL 7 12:00 NOON–6:00 pm

ECDYSONE WORKSHOP Room: Washington 2 Hall B North Organizers: Deborah Hoshizaki, University of Nevada, Las Vegas, and Christen Mirth, Janelia Farm Research Campus, HHMI The Ecdysone Workshop welcomes all those interested in the biochemistry, molecular biology, and physiology of insect hormones. We will discuss mechanisms of 20-hydroxyecdysone, juvenile hormone, and peptide hormone signaling in Drosophila, Manduca, Aedes, and other insect species. Platform talks of approximately 15 minutes will be grouped into sessions according to topic. Topics for presentation include (but will not be limited to): receptor complex/target gene interactions, downstream tissue-specific responses, and global effects of hormone exposure on insect development and physiology. Programs will be available upon request by email ([email protected] or [email protected]). 

FRIDAY, APRIL 9 1:45 pm–3:45 pm

THE MODENCODE PROJECT Room: Marriott Ballroom Salon 2 Organizers: Susan Celniker, Lawrence Berkeley National Laboratory, Gary Karpen, Lawrence Berkeley National Laboratory, Kevin White, University of Chicago and Argonne National Laboratory, and David MacAlpine, Duke University Medical Center We will give an update of the model organism ENCODE project now in its third year. The goals of the project are to identify all sequence-based functional elements in the D. melanogaster genome. Topics include the transcriptome, regulatory elements, chromatin and chromosomal proteins, small and microRNAs and origins of replication. We are using four cell lines, S2DRSC, Cl8, Kc167, DmBG3c2, and two strains, y;cn bw sp and Oregon R to conduct our studies. The data is being integrated in conjunction with a newly formed data analysis center and is available from the modENCODE website administered by the data coordination center.



FRIDAY, APRIL 9 1:45 pm–3:45 pm

CHEMICAL GENETICS AND DRUG SCREENING IN DROSOPHILA Room: Virginia Suite C Organizer: Tin Tin Su, University of Colorado, Boulder The workshop on “Chemical Genetics and Drug Screening” will cover the use of small molecules in combination with genetic manipulation to study biological phenomena. One goal of these studies is to leverage the results in designing screens for potential therapeutics for human diseases. 

FRIDAY, APRIL 9 1:45 pm–3:45 pm

RNAI SCREENING IN CELLS AND FLIES Room: Marriott Ballroom Salon 1 Organizers: Stephanie Mohr, Harvard Medical School, Cambridge, Massachusetts, Michael Boutros, German Cancer Research Center, Krystyna Keleman, Institute of Molecular Pathology, and Liz Perkins, Massachusetts General Hospital & HMS RNAi-based screening presents exciting ways for investigators to uncover gene function and genetic interactions on a genome scale. In the workshop, we will describe Drosophila RNAi resources and techniques. The first half of the workshop will discuss cell-based RNAi screening, with a focus on new innovations, such as multiplexed screening and high-content imaging. The second half will discuss resources and approaches to in vivo screening in whole animals. For both, completed or ongoing screens will be presented and discussed. The workshop will provide information on assay design, screening and analysis, as well as a list of resources.

WORKSHOPS 

FRIDAY, APRIL 9 1:45 pm–3:45 pm

DROSOPHOTOXICOLOGY: THE GROWING POTENTIAL FOR FLIES IN TOXICOLOGY RESEARCH Room: Marriott Ballroom Salon 3 Organizer: Matthew Rand, University of Vermont



27

SATURDAY, APRIL 10 6:45 pm–8:45 pm

APOPTOSIS, AUTOPHAGY AND OTHER CELL DEATH MECHANISMS Room: Marriott Ballroom Salon 2 Organizers: Andreas Bergmann, MD Anderson Cancer Center, Eli Arama, Weizmann Institute, Israel, and Michael Brodsky, University of Massachusetts Medical School

This workshop is dedicated to promoting the use of Drosophila in the modern regimen of toxicological testing. The growing demand for high throughput, high information content and low cost toxicity assays in the arenas of environmental chemical toxicology and drug development has turned considerable attention to application of small organism models. Use of Drosophila in toxicity testing is a direct response to the call for a paradigm shift to mechanism-based approaches jointly proposed by the EPA, National Toxicology Program (NTP) and National Institute of Health Chemical Genomics Center (NCGC). Presentations will highlight current examples Drosophilabased toxicological studies and discussions will center on gaining acceptance of Drosophila as a valid model for mainstream mechanism-based toxicity studies.

This workshop is a forum for the discussion of cell death mechanisms in Drosophila. Apoptosis is the most widely recognized form of cell death in development. However, there is increasing awareness that alternative cell death mechanisms exist. Autophagy has emerged as an important pathway for cell death during metamorphosis. Other non-apoptotic forms of cell death (Entosis, Necrosis) have also been described. The workshop is intended to highlight recent advances in cell death research and to foster communication and collaboration between individuals working in the field. Topics will include all aspects of cell death regulation for Drosophila biology.





SATURDAY, APRIL 10 6:45 pm–8:45 pm

SATURDAY, APRIL 10 6:45 pm–8:45 pm

EVERYTHING YOU EVER WANTED TO KNOW ABOUT SEX Room: Marriott Ballroom Salon 3 Organizers: Michelle Arbeitman, University of Southern California, Los Angeles, Artyom Kopp, University of California, Davis, Mark Siegal, NYU, and Mark Van Doren, Johns Hopkins University

DROSOPHILA RESEARCH AND PEDAGOGY AT PRIMARILY UNDERGRADUATE INSTITUTIONS (PUI) Room: Virginia Suite C Organizers: Alexis Nagengast, Widener University, Chester, Pennsylvania, Janet Rollins, College of Mount Saint Vincent, Riverdale, New York, and Thomas Onorato, LaGuardia Community College

The workshop will cover the molecular genetics, development, neurobiology, genomics, evolution, and population genetics of sexual dimorphism, with an emphasis on cross-disciplinary interactions.Presentations by invited speakers and selected abstracts from each discipline will be followed by moderated discussions. The speakers are encouraged to summarize the key ideas behind their research for people working in other fields, outline the main unsolved questions, offer their opinions about future directions, and suggest connections that could be built with other disciplines.

This workshop focuses on increasing the quality and visibility of research performed at primarily undergraduate institutions and facilitating faculty and students in these endeavors. The goals include: 1) encouraging undergraduate research by providing a forum for students to make oral presentations; 2) connecting people interested in this career path with current faculty at primarily undergraduate institutions; 3) connecting current PUI faculty for discussions and support on professional issues that differ from those at large institutions; 4) sharing concepts and techniques for using Drosophila as teaching tool in the classroom and laboratory.

28 

WORKSHOPS SATURDAY, APRIL 10 6:45 pm–8:45 pm

IMAGE ANALYSIS FOR DROSOPHILA RESEARCH Room: Marriott Ballroom Salon 1 Organizers: Pavel Tomancak, MPI-CBG, Dresden, and Uwe Ohler, Duke University, Durham, North Carolina Most primary data in biology, especially concerning phenotypes, are in the form of images. In recent years, the volume of image data has increased dramatically through high-throughput and high-resolution technologies and quantitative image analysis techniques without human intervention became indispensable for interpreting these datasets. In this workshop, we will highlight advances in image analysis on Drosophila data ranging from gene expression patterns in fixed samples, through electron microscopy of the brain, to 3d and 4d live imaging. We also aim to provide an overview of custom image analysis tools available to Drosophila research community. 

SATURDAY, APRIL 10 9:30 pm–11:30 pm

DEVELOPMENTAL REGULATION OF CELL PROLIFERATION Room: Virginia Suite C Organizer: Wu-Min Deng, Florida State University, Tallahassee, Florida The development of multicellular organisms depends on strict temporal and spatial regulation of cell proliferation patterns. In this workshop, we will focus on the regulation of several important aspects of cell proliferation in development. The topics will include: 1. Development signals that promote cell proliferation or cell cycle exit. 2. Cell cycle variations and their regulation in development. 3. Cell competition and compensatory proliferation. 

SATURDAY, APRIL 10 9:30 pm–11:30 pm

INSECT EVODEVO Room: Marriott Ballroom Salon 1 Organizer: Markus Friedrich, Wayne State University, Detroit, Michigan Drosophila is one of the most important molecular genetic systems for elucidating generic mechanisms of animal development. The gene regulatory networks, however, which organize Drosophila body plan development and organ formation, have diverse evolutionary roots. Comparative developmental studies in other insect species (insect evodevo) are essential for inferring the evolutionary origins of Drosophila development. The workshop will focus on developmental key studies in non-Drosophila insect species including other Diptera (Anopheles), beetles (Tribolium), hymenopterans (Nasonia), pea aphids (Acyrthosiphon) and crickets (Gryllus).



SATURDAY, APRIL 10 9:30 pm–11:30 pm

AUTOMATED TRACKING OF DROSOPHILA BEHAVIOR Room: Organizers:

Marriott Ballroom Salon 2 Tim Lebestky, California Institute of Technology, Pasadena, California, Andrew Straw, California Institute of Technology, Pasadena, California, and Kristin Branson, Janelia Farm Research Campus (HHMI)

The goal of this workshop is to introduce the tools and methodologies used for automated tracking and quantification of Drosophila behaviors. For those interested in questions of neural function, circuitry, and behavior, the use of these quantitative tools can facilitate both new avenues of behavioral research and a deeper understanding of phenotypic data. We will highlight the existing software that is publicly available, and provide a hands-on forum to see live hardware demos, and discuss the techniques and equipment that would be required to facilitate tracking experiments. 

SATURDAY, APRIL 10 9:30 pm–11:30 pm

GASES IN DROSOPHILA PHYSIOLOGY AND DEVELOPMENT Room: Marriott Ballroom Salon 3 Organizers: Dan Zhou, University of California, San Diego, and Greg Beitel, Northwestern University, Evanston, Illinois Gases including O2, NO and CO2 play critical roles in physiology and development. Presenters in this workshop will detail investigations of these roles as well as the molecular mechanisms by which the concentrations of specific gases are sensed and transduced to cellular processes.

Full text of all Drosophila Conference abstracts is available online at www.drosophila-conf.org where you may also conveniently access the Conference abstract search and program planner.

30

CONCURRENT PLATFORM SESSIONS THURSDAY, APRIL 8 4:30 pm–6:30 pm Program number is in bold above the title. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

Cell Biology and Signal Transduction

Evolution and Quantitative Genetics I

Moderator: Andreas Jenny, Albert Einstein College of Medicine, Bronx, NY Room: Marriott Ballroom Salon 2

Moderator: Lisa Nagy, University of Arizona, Tucson Room: Marriott Ballroom Salon 1

1 - 4:30 Cell flow reorients the axis of planar cell polarity in the Drosophila wing. Andreas Sagner1, Benoit Aigouy1, Reza Farhadifar2, Douglas Staple2, Jens-Christian Röper1, Frank Jülicher2, Suzanne Eaton1. 1) Max-Planck-Institute for Molecular Cell Biology and Genetics, Pfotenhauerstr. 108, 01307 Dresden, Germany; 2) Max-Planck-Institute for the Physics of Complex Systems, Nöthnitzer Str, 38, 01187 Dresden, Germany. 2 - 4:45 Fj kinase activity regulates Ds/Ft heterodimerization. Amy L. Brittle1, Ada Repiso2,3, José Casal3, Peter Lawrence3. 1) MRC Centre for Developmental and Biomedical Genetics, Unversity of Sheffield, UK; 2) MRC Laboratory of Molecular Biology, Cambridge, UK; 3) Department of Zoology, University of Cambridge, UK. 3 - 5:00 Clathrin adaptor complex AP-1 regulates Notch dependant binary cell fate decisions. Najate Benhra, Sylvie Lallet, Roland Le Borgne. CNRS UMR6061-IGDR, 2 av du Pr Bernard, 35000 Rennes, France. 4 - 5:15 The cytokinesis proteins Tum and Pav play a nuclear role in Wnt regulation. Amy Bejsovec1, Anna Chao1, Michael Zavortink2, Robert Saint2,3, Whitney Jones1. 1) Dept of Biology, Duke University, Durham, NC; 2) Research School of Biology, Australian National University, Canberra, Australia; 3) Dept. of Genetics, The University of Melbourne, Victoria, Australia. 5 - 5:30 FRET-FLIM assessment of a dJun Biosensor in response to Stress activation of the JNK Pathway in Cells and Embryos. Andrea M. Pereira1, Cicerone Tudor2, Hans Kanger2, Willy Supatto3, Vinod Subramaniam2, Enrique Martin-Blanco1. 1) Instituto de Biologia Molecular de Barcelona, Consejo Superior de Investigaciones Cientificas, Barcelona, Barcelona, Spain; 2) Biophysical Engineering Group, Faculty of Science and Technology, University of Twente, The Netherlands; 3) Department of Biology, California Institute of Technology, USA. 6 - 5:45 The Drosophila G-Protein Coupled Receptor Kinase Gprk2 and the B-Arrestin Kurtz Participate in Smoothened Signaling. Cristina Molnar, Mercedes Martín, Federico Mayor, Ana Ruiz-Gómez, Jose Félix de Celis. Centro de Biología Molecular “Severo Ochoa”, Universidad Autónoma de Madrid, CSIC, Madrid, Spain. 7 - 6:00 The role of the PAR-polarity complex in tracheal terminal cell development. Tiffani A. Jones, Mark M. Metzstein. Human Gen, Univ Utah, Salt Lake City, UT. 8 - 6:15 Identifying Targets of the Hippo Tumor Suppressor Pathway that regulate Growth and Proliferation. Maryam Jahanshahi1, Kuangfu Hsiao1,2, Andreas Jenny3, Cathie Pfleger1. 1) Department of Oncological Sciences, Mount Sinai School of Medicine, New York, NY; 2) Fishberg Department of Neuroscience, Mount Sinai School of Medicine, New York, NY; 3) Department of Molecular and Developmental Biology, Albert Einstein College of Medicine, Bronx, NY.

9 - 4:30 Distinct patterning mechanisms in the serially homologous appendages of the red flour beetle, Tribolium castaneum. David R. Angelini1,2, Moto Kikuchi2, Frank Smith2, Elizabeth Jockusch2. 1) Department of Biology, American University, Washington, DC; 2) Department of Ecology & Evolutionary Biology, University of Connecticut, Storrs, CT. 10 - 4:45 The evolution of gene expression in Drosophila embryogenesis. Alex T. Kalinka1, Karolina Jastrzebowska1, Dave T. Gerrard2, David Corcoran3, Stephan Preibisch1, Uwe Öhler3, Casey Bergman2, Pavel Tomancak1. 1) Max Planck Institute for Molecular Cell Biology and Genetics, Dresden, Germany; 2) Faculty of Life Sciences, The University of Manchester, 3) Institute for Genomce Sciences and Policy, Duke University. 11 - 5:00 Dynamic instability at a threshold-encoding regulatory element creates the clustered signature of developmental enhancers. Albert J. Erives, Justin Crocker. Dept Biological Sci, Dartmouth Col, Hanover, NH. 12 - 5:15 Conditionality in genetic networks: Studying the consequences of genetic background on genetic interactions using a genome wide modifier screen. Sudarshan Chari, Ian Dworkin. Zoology & EEBB, Michigan State University, East Lansing, MI. 13 - 5:30 Insights into the genetic basis of gene expression divergence in Drosophila. Colin D. Meiklejohn1, Joe D. Coolon2, Daniel L. Hartl4, Patricia J. Wittkopp2,3. 1) Biology Depart., Univ Rochester, NY; 2) Depart. of Ecology and Evolutionary Biology, Univ Michigan, Ann Arbor; 3) Depart. of Molecular, Cellular and Developmental Biology, Univ Michigan, Ann Arbor; 4) Department of Organismic and Evolutionary Biology, Harvard Univ, Cambridge, MA. 14 - 5:45 Genome-wide comparison of binding of transcription factors that control anterior-posterior patterning in D. melanogaster, D. yakuba, and D. pseudoobscura reveal pervasive quantitative changes arising from binding site turnover and chromatin divergence. Mathilde Paris1, Robert Bradley1, Xiao-Yong Li2, Mark Biggin3, Michael Eisen1,2,3. 1) Depart. of Molecular and Cell Biology, University of California Berkeley; 2) Howard Hughes Medical Institute, University of California Berkeley; 3) Genomics Division, Lawrence Berkeley National Lab, Berkeley, CA. 15 - 6:00 Development and use of a 400K SNPchip to identify highly diverged genomic regions between emerging Anopheles gambiae species and to identify loci involved in susceptibility to Plasmodium falciparum. Mara Lawniczak1, Dan Neafsey2, Seth Redmond1, Danny Park2, Mamadou Coulibaly3, Sekou Traore3, Roger Wiegand2, Frank Collins4, Nora Besansky4, Dyann Wirth5, Fotis Kafatos1, Marc Muskavitch6, George Christophides1. 1) Imperial College London, United Kingdom; 2) Broad Institute, Cambridge, MA; 3) Malaria Research and Training Center, Bamako, Mali; 4) University of Notre Dame, South Bend, IN; 5) Harvard School of Public Health, Boston, MA; 6) Boston College, Chestnut Hill, MA. 16 - 6:15 Molecular biology and evolution of candidate wasp receptors in Drosophila. Erin S. Keebaugh, Todd A. Schlenke. Dept Biol, Emory Univ, Altanta, GA.

CONCURRENT PLATFORM SESSIONS THURSDAY, APRIL 8 4:30 pm–6:30 pm Program number is in bold above the title. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

Physiology and Aging Co-Moderators: Eric Rulifson, and Sean Oldham, University of California, San Francisco Room: Marriott Ballroom Salon 3 17 - 4:30 Drosophila Sir2 maintains organismal energy balance via a nutrient-dependent catabolic switch. Tania Reis1, Marc Van Gilst2, Iswar Hariharan1. 1) Dept MCB, Univ California, Berkeley, Berkeley, CA; 2) Basic Sciences Dept, Fred Hutchinson Cancer Research Center, Seattle, WA. 18 - 4:45 Lifespan and reproduction regulation by juvenile hormone of adult Drosophila corpora allata. Marc Tatar1, Rochele Yamamoto1, Thomas Flatt1,3, Adam Dolezal2. 1) Dept Ecology & Evol Biol, Brown Univ, Providence, RI; 2) Arizona State University, School of Life Sciences Tempe, AZ; 3) Veterinärmedizinische Universität Wien, Austria. 19 - 5:00 Regulation of Receptor Tyrosine Kinase pathways in a Drosophila midgut stem cell tumor model during nutritional stress. Julio C. Cho1,2, Michele Markstein1, Norbert Perrimon1. 1) Genetics, Harvard Med Sch, Boston, MA; 2) U. Pierre et Marie Curie, Paris, France. 20 - 5:15 The Drosophila Estrogen-Related Receptor Establishes the Metabolic State that Supports Larval Growth. Jason M. Tennessen, Geanette Lam, Janelle Evans, Keith D. Baker, Carl S. Thummel. Dept. of Human Genetics, U. of Utah, Salt Lake City, UT. 21 - 5:30 Schlank, the Drosophila ceramide synthase homolog controls growth and body fat. Reinhard Bauer1, André Voelzmann1, Bernadette Breiden2, Ines Hahn1, Franka Eckardt1, Konrad Sandhoff2, Michael Hoch1. 1) LIMES-Institute, Program Unit Development & Genetics, Laboratory for Molecular Developmental Biology, University of Bonn; 2) LIMES-Institute, Program Unit Membrane Biology & Lipid Biochemistry, c/o Kekulé Institute of Organic Chemistry and Biochemistry, University of Bonn. 22 - 5:45 p38 MAP Kinase Regulates Aging and Oxidative Stress. Alysia D. Vrailas-Mortimer1,2, Subhabrata Sanyal1,2. 1) Department of Cell Biology, Emory University, Atlanta, GA; 2) Center for Behavioral Neuroscience, Atlanta, GA. 23 - 6:00 A mutation that deletes MAPK-Ak2, a direct substrate of p38 MAPK, extends lifespan in Drosophila. Erin A. Haase1, Barbara Jusiak2, Rui Chen1, Graeme Mardon1, Scott Pletcher3. 1) Molecular and Human Genetics, Baylor College of Medicine, Houston, TX; 2) Developmental Biology Program, Baylor College of Medicine, Houston, TX; 3) Department of Medicine and Interactive Physiology, University of Michigan Geriatrics Center, Ann Arbor, MI. 24 - 6:15 The non-coding RNA gene hsr-omega is a regulator of protein synthesis rates and thermotolerance in Drosophila. Travis K. Johnson, Fiona E. Cockerell, Lauren B. Carrington, Rebecca J. Hallas, Stephen W. McKechnie. Department of Biological Sciences, Monash University, Clayton, Victoria, Australia.

Notes

31

32

CONCURRENT PLATFORM SESSIONS FRIDAY, APRIL 9 8:30 am–10:15 am Program number is in bold above the title. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

Cell Biology and Cytoskeleton

Evolution and Quantitative Genetics II

Moderator: Richard Fehon, University of Chicago, Illinois Room: Marriott Ballroom Salon 2

Co-Moderators: Lisa Nagy, University of Arizona, Tucson and Leslie Pick, University of Maryland, College Park Room: Marriott Ballroom Salon 1

25 - 8:30 Integration of contractile forces during tissue invagination. Adam C. Martin1, Matthias Kaschube2, Eric F. Wieschaus1,3. 1) Dept Molecular Biol, Princeton Univ, Princeton, NJ; 2) Lewis Sigler Institute, Princeton Univ, Princeton, NJ; 3) Howard Hughes Medical Institute.

32 - 8:30 Evidence that adaptation in Drosophila is not limited by mutation at single sites. Dmitri A. Petrov1, Talia Karasov1,2, Philipp Messer1. 1) Dept Biology, Stanford University, Stanford, CA; 2) Program in Genetics, University of Chicago, Chicago, IL.

26 - 8:45 Rings lost (Rngo), an extraproteasomal polyubiquitin receptor regulates ring canal formation via the actin-cytoskeleton in Drosophila melanogaster oogenesis. Tobias Morawe, Andreas Wodarz. Department of Stem Cell Biology, University of Göttingen, Göttingen, Lower Saxony, Germany. 27 - 9:00 Dissecting the functions of Kelch during oogenesis. Andrew M. Hudson, Lynn Cooley. Dept Genetics, Yale School of Medicine, New Haven, CT. 28 - 9:15 Asymmetric distribution of Echinoid controls the planar polarity of the actin cytoskeleton during dorsal closure. Laura A. Nilson1, Caroline Laplante1,2. 1) Department of Biology, McGill University, Montreal, QC, Canada; 2) Molecular, Cell and Developmental Biology, Yale University, New Haven, CT. 29 - 9:30 Drosophila Auxilin is required for spermatid plasma membrane increase during spermatogenesis. Xin Zhou1, Lacramioara Fabian2, Jennifer Bayraktar1, Hongmei Ding1, Julie Brill2, Henry Chang1. 1) Department of Biological Sciences, Purdue University, 915 West State St, West Lafayette, IN 47907-2054, USA; 2) Program in Developmental and Stem Cell Biology, The Hospital for Sick Children, Toronto, Ontario M5G 1L7, CANADA. 30 - 9:45 Components of the single cell and multicellular wound healing responses in Drosophila. Maria T. Abreu-Blanco, Raymond Liu, Jeffrey M. Verboon, Susan M. Parkhurst. Basic Sciences Division, Fred Hutchinson Cancer Research Center. Seattle, WA 98109. 31 - 10:00 Making the apical/lateral border in Drosophila epithelial cells. Eurico Morais-de-Sá, Daniel St. Johnston. Gurdon Institute and Department of Genetics, University of Cambridge, United Kingdom.

33 - 8:45 The Effect of Inbreeding on the Metabolic Network. Anthony J. Greenberg1, Sean R. Hackett1, Lawrence G. Harshman2, Andrew G. Clark1. 1) Dept Molec Biol & Gen, Cornell Univ, Ithaca, NY; 2) School of Biol Sciences, Univ of Nebraska, Lincoln, NE. 34 - 9:00 Duplication pattern of nuclearly encoded mitochondrial genes reveals sexual antagonistic conflict in Drosophila. Miguel Gallach Caballero1, Chitra Chandrasekaran2, Esther Betrán1. 1) Department of Biology, University of Texas - Arlington. USA; 2) Department of Biology, Texas Wesleyan University. USA. 35 - 9:15 Fast rise and fall of selfish sex-ratio X chromosomes in Drosophila simulans revealed through spatio-temporal analysis of selective sweep in African populations. Héloïse Bastide, Michel Cazemajor, David Ogereau, Catherine MontchampMoreau. LEGS, CNRS UPR9034, 91198 Gif sur Yvette, France and Université Paris-Sud 11, 91405 Orsay, France. 36 - 9:30 Dosage compensation and demasculinization of X chromosomes in Drosophila. Doris Bachtrog, Nicholas Toda, Steven Lockton. Asst Prof, Integrative Biol, Univ California, Berkeley, Berkeley, CA. 37 - 9:45 Population dynamics of PIWI-RNAs (piRNAs) and their targets in Drosophila. Jian Lu, Andrew Clark. Molec Biol & Gen, Cornell Univ, Ithaca, NY. 38 - 10:00 Cryptic simplicity of the adaptive process: the role of TEs in adaptation to temperate climates. Josefa Gonzalez, Talia Karasov, Philipp Messer, Dmitri Petrov. Dept Biol, Stanford Univ, Stanford, CA.

CONCURRENT PLATFORM SESSIONS FRIDAY, APRIL 9 8:30 am–10:15 am Program number is in bold above the title. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

Neurogenetics and Neural Development Co-Moderators: Wei Xie, Southeast University, Nanjing, China and Yi Rao, Peking University, Beijing, PRC Room: Marriott Ballroom Salon 3 39 - 8:30 A novel gene implicated in synaptogenesis and N-Cadherin trafficking. Chao Tong1, Tomoko Ohyama1, Claire Haueter1, An-Chi Tien2, Akhila Rajan1, Hugo Bellen1,2,3. 1) Molecular and Human Genetics, Baylor College of Medicine, Houston, TX; 2) Program in Developmental Biology, Baylor College of Medicine, Houston, TX; 3) Howard Hughes Medical Institute,Baylor College of Medicine, Houston, TX. 40 - 8:45 Combinatorial specification of neuronal cell fates through independent temporal patterning between Notch-on and Notch-off neuronal siblings. Suewei Lin1,2, Huang-Hsiang Yu1, Jacob Sun-Jen Yang1, Yaling Huang1, Tzumin Lee1,2. 1) HHMI, Janelia Farm Research Campus, Ashburn, VA; 2) UMASS Medical School, Worcester, MA. 41 - 9:00 Functional Genomic Analyses of Transcriptional Regulation Mediating Class-IV da Neuron Dendrite Morphogenesis. Eswar P. R. Iyer, Srividya C. Iyer, Dennis Wang, Daniel N. Cox. Dept Molec & Microbiol, Krasnow Inst. Adv. Study, George Mason Univ, Fairfax, VA. 42 - 9:15 Bridging the gap between proneural genes and neuronal differentiation. Andrew P. Jarman, Sebastian Cachero, Ian Simpson, Petra Zur Lage, Lina Ma, Newton Fay. Centre for Integrative Physiology, University of Edinburgh, Edinburgh, United Kingdom. 43 - 9:30 Mutual Repression by the Transcription Factors Runt and Engrailed Specify Glial Identity. Joseph D. Watson1,2, Scott R. Wheeler1, Stephen T. Crews1. 1) Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, NC; 2) Developmental Biology Training Program, University of North Carolina, Chapel Hill, NC. 44 - 9:45 Class I and Class V HLH proteins form a cross-interacting regulatory network that regulates neuronal differentiation. Abhishek Bhattacharya, Nicholas E. Baker. Department of Genetics, Albert Einstein College of Medicine, Bronx, NY. 45 - 10:00 A 3D Compartment-Level Digital Atlas of the Adult Fruit Fly Brain. Hanchuan Peng. HHMI, Ashburn, VA.

Notes

33

34

CONCURRENT PLATFORM SESSIONS FRIDAY, APRIL 9 10:45 am–12:30 pm Program number is in bold above the title. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

Gametogenesis and Organogenesis I

Regulation of Gene Expression

Moderator: Mark Van Doren, Johns Hopkins University, Baltimore, Maryland Room: Marriott Ballroom Salon 2

Moderator: Ilaria Rebay, University of Chicago, Illinois Room: Marriott Ballroom Salon 1

46 - 10:45 Evolution of DNA binding in the Drosophila Transcription Factor hermaphrodite. Colin W. Brown1, Michael B. Eisen1,2. 1) Department of Molecular & Cell Biology, University of California, Berkeley, CA; 2) Howard Hughes Medical Institute, Berkeley, CA. 47 - 11:00 Testes specific neurotransmitter transporter required for male fertility in Drosophila melanogaster. Nabanita Chatterjee1, Janet Rollins2, Christopher Bazinet1. 1) Dept Biological Sci, St John’s Univ, Jamaica, NY; 2) Col Mt Saint Vincent, Riverdale, NY. 48 - 11:15 A sex-specific developmental regulator in the Drosophila germline. Shu Yuan Yang, Ellen Baxter, Mark Van Doren. Biology, Johns Hopkins University, Baltimore, MD. 49 - 11:30 Integrity of the nuclear lamina is required for female germline stem cell homeostasis. Belinda S. Pinto1, Lori L. Wallrath1,2, Pamela K. Geyer1,2. 1) Molecular and Cellular Biology Program, University of Iowa, Iowa City, IA; 2) Department of Biochemistry, University of Iowa, Iowa City, IA. 50 - 11:45 Polyadenylation of maternal mRNAs during oocyte maturation and egg activation in Drosophila melanogaster. Jun Cui, Mariana Wolfner. Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY. 51 - 12:00 gon1 encodes an ADAMTS required for proper cell migration during embryogenesis. Afshan Ismat, Alan Cheshire, Deborah J. Andrew. Dept Cell Biol, Johns Hopkins Sch Med, Baltimore, MD. 52 - 12:15 The Insulin Mediated PI3K Signaling Pathway Differentially Affects Apoptosis and Autophagy during Drosophila Oogenesis. Tracy L. Pritchett, Kim McCall. Department of Biology, Boston University, Boston, MA.

53 - 10:45 A novel histone fold domain-containing protein that replaces TAF6 in Drosophila SAGA is required for SAGA-dependent gene expression independent of the histone-modifying activities of the complex. Vikki M. Weake1, Selene K. Swanson1, Arcady Mushegian1,2, Laurence Florens1, Michael P. Washburn1,3, Susan M. Abmayr1,4, Jerry L. Workman1. 1) Stowers Institute for Medical Research, Kansas City, Missouri 64110; 2) Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas 66160; 3) Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, Kansas 66160; 4) Department of Anatomy and Cell Biology, University of Kansas Medical Center, Kansas City, Kansas 66160. 54 - 11:00 Shadow Enhancers Confer Robust, Adaptable Gene Expression. Alistair N. Boettiger1, Michael Perry2, Michael Levine3. 1) Biophysics Grad Group, Univ California, Berkeley, Berkleley, CA; 2) Dept Integrative Bio, Univ California, Berkeley, Berkleley, CA; 3) Dept Mol and Cell Bio, Univ California, Berkeley, Berkleley, CA. 55 - 11:15 EGFR signaling induces expression of pathway target genes by downregulating Groucho-dependent repression. Ze’ev Paroush1, Sharon Mezuman1, Dennis Kuo2, Einat Cinnamon1, Tonia Von Ohlen3, Gerardo Jiménez4, Albert Courey2, Aharon Helman1. 1) Developmental Biology and Cancer Research, IMRIC, Faculty of Medicine, The Hebrew University, Jerusalem, Israel; 2) Chemistry and Biochemistry, UCLA, Los Angeles, CA, USA; 3) Division of Biology, Kansas State University, Manhattan, KS, USA; 4) Institut de Biologia Molecular de Barcelona-CSIC and Institució Catalana de Recerca i Estudis Avançats, Barcelona, Spain. 56 - 11:30 Regulation of zerknüllt by MAPK Substrate Competition. Yoosik Kim, Stanislav Y. Shvartsman. Department of Chemical Engineering and Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ. 57 - 11:45 Analysis of cell-type specific differences in expressivity reveals a complex network motif driving robustness in the fly eye. Robert J. Johnston1, Yoshiaki Oshiaki2, Pranidhi Sood1, Edo Kussell1, Hideki Nakagoshi2, Claude Desplan1. 1) Department of Biology, New York University, New York, NY; 2) Okayama University, Japan. 58 - 12:00 Transcription Factor Recruitment and Dynamics at Endogenous Hsp70 loci. Katie L. Zobeck1, Martin S. Buckley1, Watt W. Webb2, Warren Zipfel3, John T. Lis1. 1) Mol Bio & Gen; 2) App Eng & Phys; 3) Biomed Eng, Cornell Univ, Ithaca, NY. 59 - 12:15 Runt-dependent regulation of enhancer-promoter interactions. J. Peter Gergen1, Lisa Prazak1,2. 1) Department of Biochemistry and Cell Biology and the Center for Developmental Genetics, Stony Brook University, Stony Brook, NY; 2) Graduate Program in Molecular and Cellular Biology.

CONCURRENT PLATFORM SESSIONS FRIDAY, APRIL 9 10:45 am–12:30 pm Program number is in bold above the title. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

Cell Division and Growth Control Moderator: Tian Xu, Yale University, New Haven, Connecticut Room: Marriott Ballroom Salon 3 60 - 10:45 Molecular Characterization of the drop out Locus during Cellularization. Daniel Hain, Arno Mueller. College of Life Sciences, Division of Cell and Developmental Biology, Dundee University, Dundee, United Kingdom. 61 - 11:00 Poly, a Novel Drosophila Protein,Promotes Insulin Receptor/TOR Signalling. Ekin Bolukbasi, Margarete Heck. Cardiovascular Sci, Univ Edinburgh, Edinburgh, United Kingdom. 62 - 11:15 Elimination of oncogenic neighbors by JNK-mediated supercompetition. Shizue Ohsawa1, Kaoru Sugimura2, Kyoko Takino1, Tian Xu3, Atsushi Miyawaki2, Tatsushi Igaki1. 1) Dept of Cell Biol, G-COE, Kobe Univ, Japan; 2) Lab for Cell Function and Dynamics, BSI, RIKEN, Japan; 3) Howard Hughes Medical Institute, Dept of Genetics, Yale Univ Sch of Med, USA. 63 - 11:30 Eiger/JNK signaling triggers a developmental checkpoint during regeneration and tissue neoplasia. Adrian Halme1,2, Abigail Gerhold2, Iswar K. Hariharan2. 1) Department of Cell Biology, University of Virginia, Charlottesville, VA; 2) Department of Molecular and Cell Biology, University of California, Berkeley, CA. 64 - 11:45 The apical membrane determinant Crumbs acts via the FERM-domain protein Expanded to control SWH signaling in Drosophila. Brian S. Robinson, Kenneth H. Moberg. Department of Cell Biology, Emory University School of Medicine, Atlanta, GA. 65 - 12:00 Modulating F-actin dynamics induces organ growth through the Hippo pathway. Wouter Bossuyt, Letitia Sansores, Chunyao Tao, Georg Halder. Biochem & Molec Biol, MD Anderson Cancer Ctr, University of Texas, Houston, TX, USA. 66 - 12:15 Insulin/TOR-Dependent Control of Ribosome Synthesis and Growth in Drosophila melanogaster . Lauren E. Killip1, Ling Li2, Savraj Grewal1. 1) Clark Smith Brain Tumour Center, Southern Alberta Cancer Research Institute, Department of Biochemistry and Molecular Biology, University of Calgary, Calgary AB, Canada; 2) Fred Hutchinson Cancer Research Center, Seattle WA, USA.

Notes

35

36

CONCURRENT PLATFORM SESSIONS FRIDAY, APRIL 9 4:30 pm–6:30 pm Program number is in bold above the title. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

Gametogenesis and Organogenesis II

Techniques and Functional Genomics I

Co-Moderators: Mary Van Doren, Johns Hopkins University, Baltimore, Maryland and Debbie Andrew, Johns Hopkins University, Baltimore, Maryland Room: Marriott Ballroom Salon 2

Moderator: Yikang Rong, National Institutes of Health, Bethesda, Maryland Room: Marriott Ballroom Salon 1

67 - 4:30 Nutrient stress affects polarized transport during Drosophila oogenesis. Yuko Shimada1,2, Katherine Burn2, Lynn Cooley2. 1) Graduate School of Life and Environmental Sciences, University of Tsukuba; 2) Department of Genetics, Yale University School of Medicine. 68 - 4:45 The cadherin Fat2 is required for planar cell polarity in the Drosophila ovary. Christian Dahmann, Ivana Viktorinova,Tina Koenig, Karin Schlichting. MPI-CBG, Dresden, Germany. 69 - 5:00 Swoosh, a novel MAP, is required for myonuclear positioning. Thomas Metzger1,2, Mu Xu1, Mary Baylies1. 1) Dept Development, Slaon-Kettering Institute, New York, NY; 2) BCMB program, Weill Graduate School of Medical Sciences of Cornell University, New York, NY. 70 - 5:15 The SUN protein Dspag4 recruits dynein to the nuclear periphery and cooperates with Yuri Gagarin to position basal bodies on spermatid nuclei. M. P. Kracklauer1,4, H. W. Wiora1,5, X. Chen2,6, W. J. Deery3, B. Bolival, Jr.2, D. Romanowicz1, R. A. Simonette3, M. T. Fuller2, J. A. Fischer1, K. M. Beckingham3. 1) Institute for Cell and Molecular Biology, UT Austin, 1 University Station A4800, Austin, TX 78712; 2) Departments of Developmental Biology and Genetics, Stanford University School of Medicine, Stanford, CA 94305; 3) Department of Biochemistry and Cell Biology, Rice University, Houston, TX 77005; 4) Life Sciences Institute, U Michigan, Ann Arbor, MI 48109-2216; 5) Children’s Memorial Research Center, Northwestern University, Chicago, IL 60614; 6) Department of Biology, Johns Hopkins University, Baltimore, MD 21218. 71 - 5:30 Elucidation of the mechanism involved in nuclei anchoring in muscles. Talila Volk, Hadas Elhanany-Tamir. Dept Molecular Genetics, Weizmann Inst Science, Rehovot, Israel. 72 - 5:45 Serrano (Sano) functions with the planar cell polarity genes to control tracheal tube length. Se-Yeon Chung1, Melissa Vining1, Pamela Bradley1, Chih-Chiang Chan2, Keith Wharton, Jr.2, Deborah Andrew1. 1) Dept Cell Biol, Johns Hopkins Univ, Baltimore, MD; 2) Departments of Pathology and Molecular Biology, UT Southwestern Medical Center, Dallas, TX. 73 - 6:00 Pak1 function in membrane transport of E-cadherin controls lumen shape and size. Carolyn M. Pirraglia, Jenna Walters, Monn Monn Myat. Cell & Developmental Biology, Weill Medical College of Cornell University, New York, NY. 74 - 6:15 Genome-wide transcriptional profiling reveals sex-specifically expressed transcription factors driving genital development. Sujash Chatterjee, Locke D. Uppendahl, Moin Chowdhury, Mark L. Siegal. Department of Biology, New York University, New York, NY.

75 - 4:30 MIMIC (Minos Mediated Cassette Exchange): a highly versatile transposable element for tagging genes in vivo. Koen J. T. Venken1, Karen Schulze2, Hongling Pan2, Yuchun He2, Nele Haelterman1, Joseph W. Carlson3, Roger A. Hoskins3, Hugo J. Bellen1,2,4. 1) Department of Molecular & Human Genetics, BCM, Houston, TX; 2) HHMI, BCM, Houston, TX; 3) Life Sciences Division, LBNL, Berkeley, CA; 4) Program in Developmental Biology, BCM, Houston, TX. 76 - 4:45 A tiled X chromosome duplication set with P[acman] clones. T. Kaufman1, E. Popodi1, K. Venken2, S. Holztman1, M. Phelps1, R. Eisman1, D. Miller1, K. Schulze2, J. Carlson3, R. Hoskins3, H. Bellen2. 1) DB, IU, Bloomington, IN; 2) DMHG, HHMI, BCM, Houston, TX; 3) LSD, LBNL, Berkeley, CA. 77 - 5:00 Expanding the range of a single-round targeted mutagenesis to 80 kb. Natalia Wesolowska, Yikang Rong. NCI/NIH, Bethesda, MD. 20892. 78 - 5:15 A large-scale community resource project to generate an X Chromosome Duplication Kit for genomic rescue experiments, genetic mapping and modifier screens. Kevin Cook, Russell Garton, Adam Brown, Megan Ward, Megan Deal, Jennifer Deal, Thom Kaufman, Kim Cook. Bloomington Drosophila Stock Center, Dept Biol, Indiana U, Bloomington, IN. 79 - 5:30 Rapid Identification of Heterozygous Mutations in Drosophila melanogaster using Genomic Capture Sequencing. Rui Chen1, Hui Wang1, Abanti Chattopadhyay1, Bryce Danies1, Yumei Li1, Zhe Li2, Kun Zhang2. 1) HGSC, Molec & Human Gen, Baylor Col Med, Houston, TX; 2) Department of Bioengineering, University of California at San Diego, La Jolla, California. 80 - 5:45 In toto imaging of Drosophila embryonic development. Willy Supatto, Thai V. Truong, Scott E. Fraser. California Institute of Technology, Pasadena, CA. 81 - 6:00 Bioprobe reveals localized signaling partners within aCC motoneuron during initiation of dendrites. Daichi Kamiyama1,2, Rie Kamiyama1, Mike Kim1,3, Akira Chiba1,2. 1) Molecular Institute for Molecular Imaging and Computation; 2) Biology Dept; 3) Molecular and Cellular Pharmacology Dept, University of Miami, FL. 82 - 6:15 The landscape of transcription initiation in the D. melanogaster embryo. Uwe Ohler1, Ting Ni1, David Corcoran1, Elizabeth Rach1, Eric Spana1, Yuan Gao2, Jun Zhu1. 1) Institute for Genome Sciences & Policy, Duke University, Durham, NC; 2) Virginia Commonwealth University, Richmond, VA.

CONCURRENT PLATFORM SESSIONS FRIDAY, APRIL 9 4:30 pm–6:30 pm Program number is in bold above the title. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

Chromatin and Epigenetics Moderator: Francois Karch, University of Geneva, Switzerland Room: Marriott Ballroom Salon 3 83 - 4:30 H2Av histone variant controls PARP1 activation in chromatin. Alexei Tulin, Elena Kotova, Aaron Pinnola, Yingbiao Ji. Epigenetics and Progenitor Cells Program, Fox Chase Cancer Ctr, Philadelphia, PA. 84 - 4:45 The H3K27me3-demethylase dUTX is a suppressor of Notchinduced tumors in Drosophila. Andreas Bergmann1, HansMartin Herz2, Laurence Madden3, Zhihong Chen1, Eugene Buff4, Ravi Gupta5, Ramana Davuluri5, Ali Shilatifard2, Iswar Hariharan3. 1) MD Anderson Cancer Ctr, Dept. of Biochemistry & Mol Biol, Houston, TX; 2) Stowers Institute, Kansas City, MO; 3) University of California at Berkeley Department of Molecular and Cell Biology Berkeley, CA; 4) Massachusetts General Hospital Charlestown, MA; 5) The Wistar Institute Philadelphia, PA. 85 - 5:00 The chromatin modifying complex PRC1 collaborates with sister-chromatid cohesion proteins to stabilize the synaptonemal complex and promote recombination during Drosophila meiosis. Pei Zhou, Sharon E. Bickel. Dept Biological Sci, Dartmouth College, Hanover, NH. 86 - 5:15 Drosophila Centromeric CID Nucleosome Contains Histone Octamers. Weiguo Zhang1,2, Gary Karpen1,2. 1) Life Sci Div, Lawrence Berkeley Nat Lab, Berkeley, CA; 2) Dept of Molecular and Cell Biol, University of California, Berkeley, CA. 87 - 5:30 Drosophila Piwi functions in Hsp83-mediated capacitance for morphological evolution. Vamsi Gangaraju, Hang Yin, Molly Weiner, Xiao Huang, Haifan Lin. Yale Stem Cell Center and Department of Cell Biology, Yale University School of Medicine, New Haven, CT. USA. 88 - 5:45 The endogenous siRNA pathway is involved in heterochromatin formation in Drosophila. Anne-Laure Bouge1, Delphine Fagegaltier1, Bassam Berry1, Emily Poisot2, Odile Sismeiro3, Jean-Yves Coppee3, Laurent Theodore2, Olivier Voinnet4, Christophe Antoniewski1. 1) Genetique et Epigenetique de la Drosophile, Institut Pasteur, Paris, France; 2) Laboratoire de Génétique et Biologie Cellulaire, Université de Versailles SaintQuentin-en-Yvelines, Versailles, France; 3) Genopole, Institut Pasteur, Paris, France; 4) Institut de Biologie Moleculaire des Plantes, Strasbourg, France. 89 - 6:00 Differential effects of RNA silencing on two chromatin insulators. Parul Nisha, Elissa Lei. LCDB, NIDDK, NIH, Bethesda, MD. 90 - 6:15 An insulator from even skipped mediates transgene homing and long-range enhancer-promoter communication. Miki Fujioka, James B. Jaynes. Dept Biochem & Molec Biol, Thomas Jefferson Univ, Philadelphia, PA.

Notes

37

38

CONCURRENT PLATFORM SESSIONS SATURDAY, APRIL 10 8:30 am–10:15 am Program number is in bold above the title. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

Drosophila Models of Human Disease I

Stem Cells

Moderator: Rolf Bodmer, Burnham Institute for Medical Research, La Jolla, California Room: Marriott Ballroom Salon 2

Moderator: Haifan Lin, Yale University, New Haven, Connecticut Room: Marriott Ballroom Salon 1

91 - 8:30 Smn regulates FGF signaling pathway components. Spyros Artavanis-Tsakonas1, Takakazu Yokokura1, Douglas Dimlich1, Mark Kankel1, Anindya Sen1, Anne Hart2, David Van Vactor1. 1) Dept Cell Biol, Harvard Med Sch, Boston, MA; 2) Dept Neuroscience, Brown University, Providence RI.

98 - 8:30 Paracrine UPD/JAK/STAT signaling controls intestinal stem cell self-renewal and lineage differentiation. Guonan Lin, Na Xu, Rongwen Xi. National Inst Biological Sci, Beijing, Beijing, China.

92 - 8:45 Motor neuron disease-associated mutations in P150/Glued disrupt processivity and initiation of retrograde axonal transport. Thomas E. Lloyd1,2, Katie O’Hara2, Jihan Kim1,2, Brooke Sahin1, Alex Kolodkin2. 1) Neurology, Johns Hopkins School of Medicine, Baltimore, MD; 2) Neuroscience and HHMI, Johns Hopkins School of Medicine, Baltimore, MD. 93 - 9:00 Distinct Mechanisms Underlying Tolerance to Intermittent and Constant Hypoxia in Drosophila melanogaster. Priti Azad1, Dan Zhou1, Gabriel Haddad1,2,3. 1) Dept Pediatrics, Univ California, San Diego, La Jolla, CA 92093; 2) Dept Neuroscience, Univ California, San Diego, La Jolla, CA 92093; 3) The Rady Children’s Hospital, San Diego, CA 92123, USA. 94 - 9:15 Pantethine rescues a Drosophila model for Pantothenate Kinase-Associated Neurodegeneration. Ody Sibon, Anil Rana. Cell Biology, University Medical Center Groningen, Groningen, Groningen, Netherlands. 95 - 9:30 A Drosophila model of diet-induced type 2 diabetes. Laura Palanker Musselman1, Prasanna V. Ramachandran1, Jill L. Fink1, Kirk Narzinski1, Sumitha Sukumar1, Bruce W. Patterson2, Adewole L. Okunade2, Ross L. Cagan3, Thomas J. Baranski1. 1) Endocrinology, Metabolism, and Lipid Research, Department of Medicine, Washington University School of Medicine, St. Louis, MO; 2) Division of Geriatrics and Nutritional Sciences, Department of Medicine, Washington University School of Medicine, Box 8127, 660 S. Euclid Ave, St. Louis, MO; 3) Department of Developmental and Regenerative Biology, Annenberg Building Floor 25 Room 40A, 1468 Madison Avenue, Mount Sinai School of Medicine, New York, NY. 96 - 9:45 The role of BTB zinc-finger containing proteins in regulating Drosophila neoplastic tumours. Karen Doggett, Nezaket Turkel, Helena Richardson, Anthony Brumby. Cell cycle and development, Peter MacCallum Cancer Centre, East Melbourne, Vic, Australia. 97 - 10:00 Anthrax toxins cooperate to inhibit endocytic recycling of signaling ligands. Annabel E. Guichard1, Beatriz CruzMoreno1, Shauna Mc. Gillivray2, Nina Van Sorge2, Victor Nizet2, Ethan Bier1. 1) Dept Biol, Univ California, San Diego, La Jolla, CA; 2) Dept of pediatrics, UCSD school of medicine, La Jolla CA.

99 - 8:45 STAT is required in male germline stem cells for adhesion to the niche, but not for the undifferentiated state. Judy Leatherman, Steve DiNardo. Dept Cell & Dev Biol, Univ Pennsylvania, Philadelphia, PA. 100 - 9:00 JAK/STAT regulates Heterochromatin formation to maintain Drosophila germline stem cells. Yalan Xing, Willis Li. Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY. 101 - 9:15 The NHL Domain Protein Mei-P26 Functions in both Germline Stem Cells and the Differentiating Daughters. Yun Li1, Jean Maines1, Dennis McKearin2, Michael Buszczak1. 1) Dept Molecular Biol, UT Southwestern Med Ctr, Dallas, TX,75390; 2) Howard Hughes Medical Institute, Chevy Chase, MD, 20815. 102 - 9:30 The germline stem cell self renewal factor, nanos, is a target of SXL regulation. Johnnie Chau, Helen Salz. Department of Genetics, Case Western Reserve University, Cleveland, OH. 103 - 9:45 Defining a genetic network for stem cell niche maintenance and activity in Drosophila. Justin Voog1,2, Tony D. Southall3, Gary R. Hime4, Margaret T. Fuller5, D. Leanne Jones1. 1) Laboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, CA 92037; 2) Department of Biomedical Sciences, University of California San Diego, La Jolla, CA 92037; 3) The Gurdon Institute and Department of Physiology, Development and Neuroscience, University of Cambridge, Tennis Court Road, Cambridge, UK CB2 1QN; 4) Department of Anatomy and Cell Biology, University of Melbourne, Victoria 3010, Australia and ARC Centre of Excellence in Biotechnology and Development; 5) Departments of Developmental Biology and Genetics, Stanford University School of Medicine, Stanford, CA 94305. 104 - 10:00 Tumor suppressors Sav/Scrib and oncogene Ras regulate stem cell transformation in adult Drosophila Malpighian Tubules. Xiankun Zeng, Shree Ram Singh, David Hou, Steven Hou. Mouse Cancer Genetics Program, NCI Frederick, Frederick, MD.21702.

CONCURRENT PLATFORM SESSIONS SATURDAY, APRIL 10 8:30 am–10:15 am Program number is in bold above the title. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

Pattern Formation Moderator: Paul Adler, University of Virginia, Charlottesville Room: Marriott Ballroom Salon 3 105 - 8:30 Use of FRAP in the Drosophila pupal wing to study the asymmetric localisation of the core planar polarity proteins. Samantha J. Warrington, David Strutt. University of Sheffield, Sheffield, UK. 106 - 8:45 Increased cell bond tension governs cell sorting at the Drosophila anteroposterior compartment boundary. Daiki Umetsu1, Katharina Landsberg1, Reza Farhadifar2, Jonas Ranft2, Thomas Widmann1, Thomas Bittig2, Amani Said1, Frank Jülicher2, Christian Dahmann1. 1) Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany; 2) Max Planck Institute for the Physics of Complex Systems, Dresden, Germany. 107 - 9:00 Insights into regulation of planar cell polarity by the FatDachsous pathway. Praveer Sharma1,2, Helen McNeill1,2. 1) University of Toronto, Canada; 2) Samuel Lunenfeld Research Institute, Toronto, Canada. 108 - 9:15 A genetic screen of the Drosophila second chromosome to identify genes involved in the left-right asymmetric development of the embryonic gut. Naotaka Nakazawa1, Mitsutoshi Nakamura1, Kiichiro Taniguchi1, Takashi Okumura1, Haruka Yamamoto1, Ryo Hatori1, Akira Ishio1, Ayumi Ozaki1, Reo Maeda1, Kenji Matsuno1,2. 1) Dept Biol Sci / Tec, Tokyo Univ Sci ,Noda, Japan; 2) Res Ins Sci / Tec, Tokyo Univ Sci, Noda, Japan. 109 - 9:30 Low-affinity Ci binding sites are optimal for activation of dpp and wingless by Hedgehog signaling. Scott Barolo1, Andrea I. Ramos1, David S. Parker1,2. 1) Dept. of Cell & Developmental Biology, University of Michigan Medical School, Ann Arbor, MI; 2) Current address: Dept. of Cell Biology, Duke University Medical Center, Durham, NC. 110 - 9:45 Requirements for regeneration and transdetermination. Margrit Schubiger, Anne Sustar, Gerold Schubiger. Dept Biol, Univ Washington, Seattle, WA. 111 - 10:00 Functional analysis of robustness and binding site structure in the even-skipped stripe 2 enhancer. Michael Z. Ludwig1, Manu Manu1, Ralph Kittler2, Kevin White2,1, Martin Kreitman1. 1) Dept Ecology & Evolution, Univ Chicago, Chicago, IL; 2) Dept Human Genetics, Univ Chicago, Chicago, IL.

Notes

39

40

CONCURRENT PLATFORM SESSIONS SATURDAY, APRIL 10 10:45 am–12:30 pm Program number is in bold above the title. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

Drosophila Models of Human Disease II

Techniques and Functional Genomics II

Co-Moderators: Rolf Bodmer, Burnham Institute for Medical Research, La Jolla, California and Mark Fortini, Thomas Jefferson University, Philadelphia, Pennsylvania Room: Marriott Ballroom Salon 2

Co-Moderators: Yikang Rong, National Institutes of Health, Bethesda, Maryland and Steve Hou, National Cancer Institute, Frederick, Maryland Room: Marriott Ballroom Salon 1

112 - 10:45 Loss of integrin-mediated adhesion results in muscle degeneration in Drosophila. Alexander D. Perkins, Stephanie J. Ellis, Parisa Asghari, Ash Shamsian, Edwin D. W. Moore, Guy Tanentzapf. Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, BC, Canada.

119 - 10:45 Identification of Functionally Related cis-Regulatory Enhancers. Thomas Brody1, Amar S. Yavatkar2, Leonard Tyson2, Mukta Kundu1, Jermaine Ross1, Alexander Kuzin1, Ward F. Odenwald1. 1) Neural Cell-Fate Determinants, NINDS/NIH, Bethesda, MD; 2) Information Technology Program, NINDS/ NIH, Bethesda, MD.

113 - 11:00 Dissection of the role of cerebral cavernous malformation (CCM) pathway genes in tubulogenesis using the Drosophila tracheal system as a model. Yanjun Song, Amin Ghabrial. University of Pennsylvania, School of Medicine, Philadelphia, PA.

120 - 11:00 Adaptive substitutions in Drosophila melanogaster. Bryan Kolaczkowski, Andrew Kern. Biology, Dartmouth College, Hanover, NH.

114 - 11:15 Defining the role of Muscle LIM protein in cardiomyopathy and skeletal myopathies. Kathleen A. Clark, Mary C. Beckerle. Dept. of Biology and Huntsman Cancer Inst, Univ Utah, Salt Lake City, UT. 115 - 11:30 Drosophila as a model for Emery-Dreifuss muscular dystrophy. Lori L. Wallrath1, Luka Zirbel1, Kaitlin Flannery1, Sean Speese2, Vivian Budnik2, Pamela K. Geyer1, George Dialynas1. 1) Deptartment of Biochemistry, University of Iowa, Iowa City, IA; 2) Deptartment of Neurobiology, University of Massachusetts, Worcester, MA. 116 - 11:45 Reduction of Wunen suppresses Dystrophin muscle phenotypes. Mario Pantoja, Karin Fischer, Hannele Ruohola-Baker. Dept Biochem, Univ Washington, Seattle, WA. 117 - 12:00 DSCAM and COL6A2 Cooperate to Produce Down Syndrome Congenital Heart Defects. Tamar R. Grossman1, Amir Gamliel2, Robert J. Wessells3, Ouarda Taghli-Lamallem4, Kristen Jepsen2, Karen Ocorr4, Kirk L. Peterson5, Julie R. Korenberg6, Michael G. Rosenfeld2, Rolf Bodmer4, Ethan Bier1. 1) Sec Cell & Dev Biol, UCSD, La Jolla, CA; 2) HHMI, School of Medicine, UCSD, La Jolla, CA; 3) Univ of Michigan, Ann Arbor, MI; 4) Burnham Institute of Medical Research, La Jolla, CA; 5) School of Medicine, UCSD, La Jolla, CA; 6) The Brain institute, School of Medicine, Univ of Utah, Salt Lake City, UT. 118 - 12:15 PP1 Regulatory Subunit Sds22: a Drosophila Model for Metastasis. Yuwei Jiang1, Su-Jin Kwak2, Keqing Wang5, Rui Chen1,5, Graeme Mardon1,2,3,4. 1) Dept Molecular and Human Genetics, Baylor College of Medicine, Houston, TX; 2) Pathology, Baylor College of Medicine, Houston, TX; 3) Neuroscience, Baylor College of Medicine, Houston, TX; 4) Program in Dev. Biology, Baylor College of Medicine, Houston, TX; 5) Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX.

121 - 11:15 Gene transpositions in the Drosophila genome. Mira Han1, Matthew Hahn1,2. 1) Dept Informatics, Indiana Univ, Bloomington, IN; 2) Dept Biology, Indiana Univ, Bloomington, IN. 122 - 11:30 Systematic identification and analysis of cis-regulatory regions using DNA binding motifs and pattern generating potential. Michael H. Brodsky1, Majid Kazemian2, Charles Blatti2, Adam Richards1, Michael McCutchan3, Sudhir Kumar3, Scot Wolfe1, Saurabh Sinha2. 1) University of Massachusetts Medical School, Worcester, MA; 2) University of Illinois at Urbana-Champaign; 3) Arizona State University. 123 - 11:45 Maximum Potential ORFs buffer the effects of frequent indels and changes in intron-exon structure during the rapid evolution of Drosophila proteins. R. C. Eisman, S. Middha, P. Cherbas, T. C. Kaufman. Dept Biol, Indiana U, Bloomington, IN. 124 - 12:00 Transformation in Sciara coprophila using a versatile vector piggyBac[3xP3-EGFPfa]attP-ZFNT. Yutaka Yamamoto1, 2 1 Fyodor Urnov , Susan Gerbi . 1) Brown University, Molecular Biology, Cell Biology and Biochemistry Dept, Providence, RI; 2) Sangamo BioSciences, Point Richmond Tech Center, Richmond, CA. 125 - 12:15 Evolutionary mirages: selection on binding site composition creates the illusion of conserved grammars in Drosophila enhancers. Richard W. Lusk1, Michael B. Eisen1,2. 1) Dept Mol & Cell Biol, UC Berkeley, Berkeley, CA; 2) HHMI UC Berkeley, Berkeley, CA.

CONCURRENT PLATFORM SESSIONS SATURDAY, APRIL 10 10:45 am–12:30 pm Program number is in bold above the title. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

RNA Biology Moderator: Richard Carthew, Northwestern University, Evanston, Illinois Room: Marriott Ballroom Salon 3 126 - 10:45 Defining microRNA function with precise spatiotemporal resolution in intact organisms. Tudor A. Fulga, Carlos M. Loya, Cecilia S. Lu, David Van Vactor. Department of Cell Biology, Harvard Medical School, Boston, MA. 127 - 11:00 Epigenetic Trans-Silencing Effect in the germline: towards a reciprocal dependance between piRNAs and heterochromatin. Augustin de Vanssay1, Anne-Laure Todeschini2, AnneLaure Bougé3, Laure Teysset1, Valérie Delmarre1, Christophe Antoniewski3, Stéphane Ronsseray1. 1) Biologie du Développement, CNRS - UMR7622, Paris, France; 2) Institut Jacques Monod, UMR7592, CNRS-Université Denis Diderot, Paris, France; 3) CNRS, URA2578, Institut Pasteur, 25 rue du Dr Roux, F75015 Paris, France. 128 - 11:15 HP1 recruitment in the absence of Argonaute proteins. Nellie Moshkovich1,2, Elissa Lei1. 1) Laboratory of Cellular and Developmental Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA, 20892; 2) The Graduate Program in Molecular and Cell Biology, University of Maryland, College Park, MD, USA 20742. 129 - 11:30 Reconstruction of Splicing Regulatory Networks from High Throughput Transcriptome Data. Panagiotis Papasaikas1, Peter Huggins2, Arvind Rao2, Judith Savitskaya1, A. Javier Lopez1,2. 1) Biological Sci, Carnegie Mellon Univ, Pittsburgh, PA; 2) Lane Center for Computational Biology, Carnegie Mellon Univ, Pittsburgh, PA. 130 - 11:45 Exon Junction Complex components are specifically required to process the large MAP kinase transcript in Drosophila. Jean Y. Roignant, Jessica Treisman. Dept Developmental Genetics, Skirball Inst, New York, NY. 131 - 12:00 High resolution analysis reveals the hierarchical assembly of endogenous oskar mRNA particles for motor-dependent transport in the Drosophila oocyte. Alvar Trucco, Imre Gaspar, Anne Ephrussi. Developmental Biology, European Molecular Biology Laboratory, Heidelberg, Germany. 132 12:15 Trailer hitch is a localization factor for a novel class of RNPs that contain the translational repressor Hubcap. James Wilhelm, Elena Monfort-Prieto, Risa Broyer. Section on Cell and Developmental Biology, UC San Diego, La Jolla, CA.

Notes

41

42

CONCURRENT PLATFORM SESSIONS SATURDAY, APRIL 10 4:00 pm–6:00 pm Program number is in bold above the title. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

Cell Cycle and Cell Death

Neural Physiology and Behavior

Moderator: Laura Johnston, Columbia University, New York Room: Marriott Ballroom Salon 2

M o d e ra t o r : Jay H i r s h , U n i ve r s i t y o f V i r g i n i a , Charlottsville Room: Marriott Ballroom Salon 1

133 - 4:00 The Drosophila Cks85A is required for the maintenance of genomic stability and interacts with mitotic Cdks and the SCFSkp2 complex. Mohammad Ghorbani, Andrew Swan, Emona Kraja. Biological Sciences, University of Windsor, windsor, Ontario, Canada.

141 - 4:00 The structure of the afferent auditory pathway in Drosophila melanogaster. Alexander G. Vaughan, Bruce Baker. Janelia Farm Research Campus, Ashburn, VA.

134 - 4:15 Cell death regulators control mitochondrial dynamics in late oogenesis. Elizabeth A. Tanner, Kim McCall. Dept Biol, Boston Univ, Boston, MA.

142 - 4:15 Genetic analysis of ecdysis behavior in Drosophila. John Ewer1, Eleanor Lahr2, Dean Derek3. 1) Centro de Neurociencia, Universidad de Valparaiso, Valparaiso, CHILE; 2) Division of Biological Sciences, The University of Montana, Missoula, MT; 3) Department of Biology, Williams College, Williamstown, MA.

135 - 4:30 Genome wide analysis of Drosophila follicle cell amplicons reveals diversity of amplification origin control mechanisms. Jane C. Kim, Helena Kashevsky, Terry L. Orr-Weaver. MIT Department of Biology & Whitehead Institute, Cambridge, MA.

143 - 4:30 The TRP channel painless mediates gustatory DEET sensation in Drosophila melanogaster. Jason C. Caldwell, Yifan Xu, W. Daniel Tracey. Dept Anesthesiology, Duke Univ Med Ctr, Durham, NC.

136 - 4:45 The pachytene checkpoint monitors chromosome axis structure and can induce interchromosomal effects on crossing over during female meiosis. Eric Joyce, Kim McKim. Waksman Inst, Rutgers Univ, Piscataway, NJ.

144 - 4:45 importin-A2 is Critical for Mushroom Body Development and Classical Conditioning. C. N. Serway1, B. S. Dunkelberger1, D. Beck1, N. W. C. Nolan1,2, S. Freer1,3, J. S. de Belle1. 1) UNLV, Las Vegas, NV; 2) Creighton University Medical School, Omaha, NE; 3) UNC, Chapel Hill, NC.

137 - 5:00 Fat-Hippo Signaling Regulates the Proliferation and Differentiation of Drosophila Optic Neuroepithelia. Venu Bommireddy Venkata, Cordelia Rauskolb, Ken Irvine. Molecular biology and Biochemistry Waksman Institute, Piscataway, NJ. 138 - 5:15 Reaper’s stability is regulated through a non-lysine ubiquitination mechanism. Celia Domingues, Hyung Don Ryoo. Dept Cell Biol, New York Univ, New York, NY. 139 - 5:30 A novel cell cycle program and an in vivo model of polyploid mitosis. Donald T. Fox1,2, Joseph G. Gall1, Allan C. Spradling1,2. 1) Dept Embryology, Carnegie Inst, Baltimore, MD; 2) Howard Hughes Medical Institute. 140 - 5:45 Psf2, a replication protein, plays a dual role in cell cycle progression. Laura Henderson, Tim Christensen. Dept Biol, East Carolina Univ, Greenville, NC.

145 - 5:00 The Drosophila Orb2, a gene required for stable long-term memory, has Prion-like properties. Amitabha Majumdar, Kausik Si. Si lab, Stowers Institute for Medical Research, Kansas City, MO. 146 - 5:15 Akt Regulates a Diametric Response to Alcohol by Neurons and Glia. Mark Eddison1, Douglas Guarnieri2, Che Hsiung Liu3, Kevin Moffat3, Ulrike Heberlein1. 1) UCSF, Dept of Anatomy, Box2822, San Francisco, CA 94158; 2) Dept. of Psychiatry and Neurobiology, Yale University School of Medicine, New Haven, CT 06510; 3) Dept of Biological Sciences, University of Warwick, Coventry CV4 7AL, U. K. 147 - 5:30 Regulation of Metabolism by Light, Behavior and the Circadian Clock. Daniel Seay, Carl Thummel. Human Genetics, University of Utah, Salt Lake City, UT. 148 - 5:45 The Dopamine Receptor (DopR) is Involved in Multiple Dimensions of Arousal. Tim J. Lebestky1, Jung Sook Chang1, Heiko Dankert2, Pietro Perona2, David Anderson1. 1) Department of Biology, 216-76, Caltech, Pasadena, CA; 2) Division of Engineering and Applied Science, 136-93, Caltech, Pasadena, CA.

CONCURRENT PLATFORM SESSIONS SATURDAY, APRIL 10 4:00 pm–6:00 pm Program number is in bold above the title. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

Immunity and Pathogenesis Moderator: Ylva Engstrom, University of Stockholm, Sweden Room: Marriott Ballroom Salon 3 149 - 4:00 Role of Rab14 during phagosome maturation in Drosophila melanogaster. Aprajita Garg, Melek Erdinc, Katherine Randle, Louisa Wu. University of Maryland Biotechnology Institute, College Park, MD. 150 - 4:15 Full of Bacteria (fob) is required for normal phagosome maturation. Mohammed A. Akbar, Charles Tracy, Helmut Krämer. Dept of Neuroscience, Univ Texas SW Medical Ctr, Dallas, TX. 151 - 4:30 Uric Acid: Balancing reactive oxygen damage to host and microbe during infection in Drosophila melanogaster. Moria C. Chambers, Alex Louie, David Schneider. MicroBiol & Immunology, Stanford Univ, Stanford, CA. 152 - 4:45 Regulation of the Drosophila innate immune response by stalled polymerase. Linh N. Pham, Daniel A. Gilchrist, Karen Adelman. Laboratory of Molecular Carcinogenesis, NIEHS, Research Triangle Park, NC. 153 - 5:00 Intestinal Dysplasia in Genetically Predisposed and Bacterially Infected Drosophila . Yiorgos Apidianakis1, Chrysoula Pitsouli2, Norbert Perrimon2, Laurence Rahme1. 1) Dept Surgery, Massachusetts General Hosp, Boston, MA; 2) Dept Genetics, Harvard Medical School, Boston, MA. 154 - 5:15 Pathogen Entrapment by Transglutaminase - a Conserved Early Innate Immune Mechanism. Zhi Wang1, Christine Wilhelmsson1, Pavel Hyrsl1,3, Torsten Loof2, Pavel Dobes1,3, Heiko Herwald2, Ulrich Theopold1. 1) Dept. of Molecular Biology and Functional Genomics, Stockholm University, Stockholm, Sweden; 2) Department of Clinical Sciences, Lund University, 22184 Lund, Sweden; 3) Department of Animal Physiology and Immunology, Institute of Experimental Biology, Masaryk University, 611 37 Brno, Czech Republic. 155 - 5:30 Drosophila C virus induced pathology in adult flies. Stanislava Chtarbanova, Delphine Galiana-Arnoux, Jean-Luc Imler. UPR9022 du CNRS , Strasbourg, France. 156 - 5:45 Insertions and Deletions as Mediators of Host-Pathogen Conflict in a Newly Discovered Immune-Response Protein. Nathaniel L. Clark, Sun Woo Kim, Charles F. Aquadro. Molecular Biology and Genetics, Cornell University, Ithaca, NY.

Notes

43

44

POSTER SESSIONS Poster board number is in bold above the title. See page 15 for presentation schedule. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

Cell biology and signal transduction 157A Identifying Rap1 Interacting Genes in Drosophila Eye Development. C. Amesoli1, E. Gonzalez-Nino1, K. Kee1, D. O’Keefe2, B. Edgar2, J. Curtiss1. 1) New Mexico State University; 2) Fred Hutchinson Cancer Research Center. 158B Molecular mechanisms by which Crumbs / CRB3 regulate epithelial integrity and tumour growth. François J. Chartier, Jim Boulanger, Patrick Laprise. Medical Biology, Laval University Cancer Research Center, CRCHUQ-Hôtel-Dieu de Québec, 9 McMahon, QC, G1R 2J6, Canada. 159C Characterization of the Early Frizzled PCP signal in the Drosophila wing. Simon Collier, Justin Hogan, Chris Cox, Kathryn Crim, Jessica Layne. Dept Biological Sci, Marshall Univ, Huntington, WV. 160A Javelin-like: A new player in polarizing Drosophila eggchamber. Dikla Dubin Bar, Amir Bitan, Anna Bakhrat, Uri Abdu. Department of Life sciences and the National Institute for Biotechnology in the Negev, Ben Gurion Univ, Beer-Sheva, Israel. 161B Four-jointed is a Golgi kinase that phosphorylates cadherin domains. Hiroyuki O. Ishikawa1, Hideyuki Takeuchi2, Robert S. Haltiwanger2, Kenneth D. Irvine3. 1) Graduate School of Science, Chiba University, Japan; 2) Institute for Cell and Developmental Biology, Stony Brook University, Stony Brook, NY; 3) HHMI/Waksman Institute, Rutgers University, Piscataway, NJ. 162C The Drosophila Planar Polarity proteins Multiple Wing Hairs and Inturned Interact Physically and Function Together. Qiuheng Lu, Jie Yan, Paul Adler. Biology Department, Morphogenesis and Regenerative Medicine Institute and Cancer Center,University of Virginia, Charlottesville, VA. 163A Zona Pellucida Domain proteins remodel the apical compartment for localized cell shape changes. Serge Plaza1, Isabelle Fernandes1,2, Helene Chanut1, Pierre Ferrer1, Yvan Latapie1, Lucas Waltzer1, Markus Afolter3, Francois Payre1. 1) Ctr de Biol du development, Univ Paul Sabatier, toulouse, France; 2) McGill University, Montreal, Quebec; 3) Biozentrum der Universität Basel, Basel, Switzerland. 164B Role of Ubiquitin in Regulating Planar Cell Polarity. Elizabeth Searle, Helen Strutt, David Strutt. University of Sheffield, Sheffield, United Kingdom. 165C Identification of genes required for axis elongation in Drosophila. Athea Vichas, Justina Sanny, Masako Tamada, Gillian Siegal, Jennifer Zallen. Howard Hughes Medical Institute, Dept Dev Bio, Sloan Kettering Institute, New York, NY.

166A Elucidating the role of javelin during Drosophila bristle elongation. Shira Avrani, Amir Bitan, Uri Abdu. Life Sciences, Ben-Gurion Univ, Beer-sheba, Israel. 167B Role of Drosophila chloride intracellular channel (Clic) in dorsal closure. M. Berryman1,3, K. Hawley1, R. Price2, S. Tanda2,3. 1) Dept. Biomedical Sciences; 2) Dept. Biological Sciences; 3) Molecular and Cellular Biology Program, Ohio University, Athens, OH 45701. 168C The Drosophila bristle is a model system for asymmetric microtubule organization in a polarized cell. Amir Bitan1, Gregory M. Guild2, Dikla Bar-Dubin1, Uri Abdu1. 1) Department of Life Sciences and the National Institute for Biotechnology in the Negev, Ben-Gurion University, Beer-Sheva, Israel; 2) Department of Biology, University of Pennsylvania, Philadelphia, PA, USA. 169A The Role of PIP2 in Drosophila Myoblast Fusion. Ingo Bothe, Mary Baylies. Developmental Biology, Memorial SloanKettering Cancer Center, New York, NY. 170B Contributions of the PINCH-Integrin Linked Kinase interaction to integrin function in Drosophila embryonic muscle. Maria C. Elias1,2, Julie L. Kadrmas1,2, Mary C. Beckerle1,2,3. 1) Dept of Oncological Sciences, University of Utah, Salt Lake City, UT; 2) Huntsman Cancer Institute, University of Utah, Salt Lake City, UT; 3) Dept of Biology, University of Utah, Salt Lake City, UT. 171C Drosophila RSU1 is regulated by its interaction with PINCH. Julie Kadrmas1,2, Maria Elias1,2, Stephen Pronovost1, Mary Beckerle1,2,3. 1) Huntsman Cancer Institute; 2) Department of Oncological Sciences; 3) Department of Biology, University of Utah, Salt Lake City, UT. 172A PAR-1 Phosphorylates Shot and Controls its Oocyte. Dmitry Nashchekin, Antonio Vega-Rioja, Daniel St. Johnston. Gurdon Institute, University of Cambridge, Cambridge, United Kingdom. 173B The WASp -based actin nucleation system is required in somatic cyst cells for spermatid release. Eyal D. Schejter, Shay Rotkopf, Ben-Zion Shilo. Dept Molec Gen, Weizmann Inst Sci, Rehovot, Israel. 174C Mining localized mRNAs in late-stage Drosophila oocytes. Huadi Zhang, Kathleen Raley-Susman, Nancy Pokrywka. Biology Department, Vassar College, Poughkeepsie, NY. 175A Characterizing the signaling pathways regulating myosin transcription during Drosophila dorsal closure. Xi Chen1, Weiping Shen2, Nicholas Harden1. 1) Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC, Canada; 2) Laboratory of Genetics, National Institute on Aging, NIH Biomedical Research Center, Baltimore, MD.

POSTER SESSIONS

45

Poster board number is in bold above the title. See page 15 for presentation schedule. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

176B Constraining Dpp Signaling Fields in the Embryonic Epidermis of Drosophila. Gregory B. Humphreys, Kate Monroe, Anthea Letsou. Human Gen, Univ Utah, Salt Lake City, UT. 177C Positive feedback regulation of WIT controls BMP signaling in Drosophila oogenesis. Rob Marmion, Nir Yakoby. Dept. Biology and Center for Computational and Integrative Biology, Rutgers University, Camden, NJ. 178A The Molecular Basis for Sog-mediated Transport of BMPs. C. Peluso1, D. Umulis2, Y. Kim1, M. O’Connor3, M. Serpe1. 1) PCRM, NICHD, NIH, MD; 2) Agr and Bio Engineering, U Purdue, IN; 3) GCD, HHMI/U Minnesota, MN. 179B Drosophila cytonemes are ligand-specific cell extensions that ferry signaling proteins. Sougata Roy, Frank Hsiung, Thomas B. Kornberg. Cardiovascular Research Institute, University of California San Francisco, San Francisco, CA. 180C Role of Chmp1 Protein in Drosophila. Meagan Valentine1, Maiyon Park2, Simon Collier1. 1) Marshall University, Huntington, WV; 2) Marshall University School of Medicine, Huntington, WV. 181A Distinct and common characteristics of ESCRT-II components vps22, vps25, and vps36. Sarah E. Woodfield1,2, Jacob Hernandez1, Hans-Martin Herz3, Andreas Bergmann1,2. 1) Biochemistry & Molecular Biology, Unit 1000, UT MD Anderson Cancer Center, Houston, TX; 2) Program in Developmental Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX; 3) Stowers Institute for Medical Research, Kansas City, MO. 182B Interactions of membrane-bound and extracellular matrix proteins in secretion and spreading of the Hedgehog morphogen in the Drosophila wing disc. Aphrodite Bilioni, Emanuela Mollica, Ainhoa Callejo, Javier Sierra, Nicole Gorfinkiel, Carlos Torroja, Carmen Ibañez, Isabel Guerrero. Centro de Biología Molecular Severo Ochoa, UAM-CSIC, Madrid 28049, Spain. 183C Drosophila Homologue of mammalian GOLPH3, Rotini, Modulates the Retrograde Trafficking of Exostosin Proteins in Golgi complex. Wei-Ling Chang, Che-Wei Chang, Yu-Yun Chang, Hsin-Ho Sung, Chung-Hao Chen, Tze-Bin Chou. Institute of Molecular and Cellular Biology, National Taiwan University, Taipei, Taiwan. 184A Gint3 function and expression during embryogenesis in Drosophila embryos. Clarissa M. Cheney, Kimberly M. Chau, Benjamin M. Kozak. Dept Biol, Pomona Col, Claremont, CA.

185B The sorting adaptor GGA in Drosophila melanogaster is essential and is required for normal lysosome function. Joel C. Eissenberg1, Anne M. Ilvarsonn1, William S. Stark3, Regina Pohlmann2, William S. Sly1, Abdul Waheed1, André C. Dennes2. 1) Dept Biochem & Molec Biol, St Louis Univ Med Sch, St Louis, MO, USA; 2) UKM Münster, Inst. Physiol Chem & Pathobiochem, Münster, Germany; 3) Dept Biology, St Louis Univ, St Louis, MO, USA. 186C Formation of Dorsal morphogen gradient: Insights from mathematical modeling. Jitendra S. Kanodia1,2, Stanislav Y. Shvartsman1,2. 1) Department of Chemical Engineering, Princeton Univ, Olden St, Princeton, NJ-08544; 2) Lewis Sigler Institute for Integrative Genomics, Princeton Univ, Washington Road, Princeton, NJ-08544. 187A Controlled Turnover of the Motor Regulator Halo. Nicholas P. Rizzo1, Susan L. Tran1, Joseph G. Gindhart2, Michael A. Welte1. 1) Department of Biology, University of Rochester, Rochester, NY; 2) Division of Cell Biology and Biophysics, NIGMS, The National Institute of Health, Bethesda, Maryland. 188B Quality control receptor Rer1 affects eye and bristle development in Drosophila. Milos R. Spasic, Wendy Vermeire, Hui Qi Lu, Wim Annaert. Laboratory for Membrane Trafficking, Center for Human Genetics (VIB - KU Leuven), Leuven, Belgium. 189C docked - dumpy Interactions During Wing Development. Justin R. Thackeray, Suresh Kumar Kandasamy, Kiley Maguire. Biology Department, Clark University, Worcester, MA. 190A Halo controls lipid-droplet motion via physical interactions with Kinesin-1 and Dynein. Michael A. Welte, Susan L. Tran, Gurpreet K. Arora. Dept Biol, Univ Rochester, Rochester, NY. 191B A dual function of the v-ATPase reveals a neuron-specific degradation pathway in Drosophila. W. Ryan Williamson1,3, Dong Wang1,3, P. Robin Hiesinger1,2. 1) Dept Physiology, UT Southwestern Med Ctr, Dallas, TX; 2) Green Center for Systems Biology, UT Southwestern Med Ctr, Dallas, TX; 3) equal contribution. 192C Klarsicht interacts with kinesin-1 and cytoplasmic dynein through separable domains. Yanxun V. Yu1, Sean L. Cotton2, Michael A. Welte1. 1) Dept. of Biology, University of Rochester, Rochester, NY; 2) Boston University, Boston, MA. 193A Identification of JAK/STAT pathway target genes as effectors of blood tumour formation. Samira Bina1,2, Victoria Wright1,2, Katie Fisher1,2, Marta Milo3, Martin Zeidler1,2. 1) Biomedical Sci, University of Sheffield, UK; 2) MRC Centre for Developmental & Biomedical Genetics; 3) NIHR Cardiovascular Biomedical Research Unit, Sheffield, UK. 194B The interaction between two JAK signaling ligands: Upd and Upd3. Qian Chen, Shanshan Pei, Douglas Harrison. Dept Biol, Univ Kentucky, Lexington, KY.

46

POSTER SESSIONS Poster board number is in bold above the title. See page 15 for presentation schedule. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

195C The Mighty Morphogen Powering the Ovary: The Distribution of the JAK/STAT Ligand Unpaired (Upd) During Oogenesis. D. W. Perry, T. R. Sexton, D. A. Harrison. Department of Biology, University of Kentucky, Lexington, KY. 196A Identification of Ligand-Specific Mechanisms of JAK/STAT Regulation. Victoria M. Wright, Stephen Brown, Martin P. Zeidler. Department of Biomedical Science, University of Sheffield, Sheffield, United Kingdom. 197B Fry is highly mobile in bristles and da neurons. Xiaolan Fang1, Kazuo Emoto2, Yuh-Nung Jan3, Paul Adler1. 1) Dept Biol, Univ Virginia, Charlottesville, VA; 2) Neural Morphogenesis Laboratory, National Institute of Genetics, Mishima, Japan; 3) Howard Hughes Medical Institute, Department of Physiology, University of California at San Francisco, San Francisco, CA. 198C Intrinsic and extrinsic factor regulate the in-vivo dynamics of integrin-mediated adhesion in fly muscles. Guy Tanentzapf, Lin Yuan, Mary Pines, Ari Franco-Cea, Michael Fairchild, Alexander Perkins. CPS Dept, Univ British Columbia, Vancouver, BC, Canada. 199A Spatiotemporal modulation of Rap1 GTPase activity structures epithelial invagination during Drosophila gastrulation. Yu-Chiun Wang, Eric Wieschaus. Department of Molecular Biology, Princeton University, Princeton, NJ. 200B Analysis of Border and Centripetal Cell Migration in Drosophila. Elena Domanitskaya, Yi Sun, Yan Yan, Natalie Denef, Trudi Schupbach. HHMI / Department of Molecular Biology, Princeton University, Princeton, NJ. 201C Trafficking through the recycling endosome spatially restricts Receptor Tyrosine Kinase activity during border cell migration. Gregory Emery1,2, Gloria Assaker1, Stephanie Wculek1. 1) IRIC, Université de Montréal, Montréal, Canada; 2) Département de Pathologie et Biologie Cellulaire, Université de Montréal, Montréal, Canada. 202A An in vivo RNAi screen for Genes that Control Collective Cell Migration in Drosophila. Li He, Xiaobo Wang, Anna C.-C. Jang, Denise Montell. Biological Chemistry, Johns Hopkins Univ, Baltimore, MD. 203B Characterization of a novel gene involved in border cell migration. Wei-Hao Li, Lei-Mei Pai. Chang Gung university 259 Wen-Hwa 1st Road, Kwei-Shan Tao-Yuan Taiwan. 204C Characterization of cell adhesion changes that promote detachment from the ovarian epithelium. Lathiena A. Manning, Michelle Starz-Gaiano. Biological Sciences, University of Maryland Baltimore County, Baltimore, MD.

205A The nesthocker mutation reveals requirement of O-GlcNAcylation for FGF-signalling in Drosophila. Daniel N. Mariyappa1, Kathrin Sauert2, Daniel Turnock3, Karina Mariño3, Vladimir Borodkin4, Daan Van Aalten4, Micheal Ferguson3, Arno Müller1. 1) Division of CDB, CLS, University of Dundee, Dundee, United Kingdom; 2) Institut für Genetik, Heinrich-Heine Universität Düsseldorf, Düsseldorf, Germany; 3) BCDD, CLS, University of Dundee, Dundee, United Kingdom; 4) Division of MM, CLS, University of Dundee, Dundee, United Kingdom. 206B A dominant modifier screen to identify novel components of Abl signaling pathways. Christopher S. Moline, Kristina M. Reiss, Caron M. Leonard, Traci L. Stevens. Biology, RandolphMacon College, Ashland, VA. 207C Phospholipid signaling regulates primordial germ cell migration. Brian E. Richardson1, Ruth Lehmann1,2. 1) Skirball Institute, Department of Cell Biology, NYU School of Medicine, New York, NY; 2) Howard Hughes Medical Institute. 208A The serine protease homologue gene scarface is a target of JNK signalling that regulates epithelial morphogenesis in Drosophila. Raphael Rousset1, Sophie Bono-Lauriol1, Melanie Gettings1, Magali Suzanne2, Pauline Spéder3, Stéphane Noselli1. 1) Institute of Developmental Biology and Cancer, CNRS UMR 6543, University of Nice, Nice, France; 2) HHMI, The Rockefeller University, New York, NY 10065, USA; 3) The Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge CB2 1QN, UK. 209B JNK Regulates Mmp1 Expression Post-Wounding in Drosophila melanogaster Larvae. Laura J. Stevens, Shaina Feldman, Andrea Page-McCaw. Dept Biol, RPI, Troy, NY. 210C Clasp Mediated Microtubule Bundling Regulates Directed Migration and Contact Inhibition in Drosophila Macrophages In Vivo. Brian Stramer1, Severina Moreira2, Tom Millard3, Iwan Evans4, Ola Sabet4, Martin Milner5, Graham Dunn1, Paul Martin2, Will Wood4. 1) Randall Division of Cell and Molecular Biophysics, King’s College London, London, United Kingdom; 2) Departments of Biochemistry and Pharmacology, University of Bristol, Bristol, United Kingdom; 3) Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom; 4) Department of Biology and Biochemistry, University of Bath, Bath, United Kingdom; 5) School of Biology, University of St. Andrews, St. Andrews, United Kingdom. 211A Repression of alternative fates is initiated by Notch and maintained by Polycomb Group genes in R7 photoreceptors. Jennifer K. Jeffress, Adam Miller, Tory Herman. Institute of Molecular Biology, University of Oregon, Eugene, OR.

POSTER SESSIONS

47

Poster board number is in bold above the title. See page 15 for presentation schedule. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

212B A Systems Biology Approach to Notch Signaling in Drosophila Reveals an Extensive Interaction Network with New Modules Linking Notch to Cancer. Abil Saj1, Zeynep Arziman2, Denise Stempfle1, Werner van Belle1, Thomas Horn2, Renato Paro1, Michael Boutros2, Gunter Merdes1. 1) Dpt. Biosystems Science and Engineering, ETH Zurich, Basel, Basel, Switzerland; 2) German Cancer Research Center (DKFZ), Division of Signaling and Functional Genomics, INF 580, 69120 Heidelberg, Germany. 213C uninflatable regulates Notch signaling in imaginal discs. Patrick Sturdivant, Liang Zhang, Robert Ward. Molecular Biosciences, University of Kansas, Lawrence, KS. 214A Drosophila Epsin functions as a Clathrin Adapter in Notch Signaling. Xuanhua Xie, Janice Fischer. Dept MCDB, Univ Texas, Austin, Austin, TX. 215B The vacuolar proton pump (V-ATPase) is required for Notch signaling and endosomal trafficking in Drosophila. Yan Yan1, Natalie Denef1,2, Trudi Schüpbach1,2. 1) Dept Molec Biol, Princeton Univ, Princeton, NJ; 2) HHMI. 216C Poly(ADP-ribose)Polymerase 1 Regulates Nucleolar Functions and Translation. Ernest Kojo Boamah, Alexei Tulin. Epigenetics and Progenitor Cells Program, Fox Chase Cancer Center, Philadelphia, PA. 217A Screen for genetic modifiers of the Atg1-induced rough eye phenotype in Drosophila. Guang-Chao Chen1,2, Hong-Wen Tang2, Li-Jin Chuang2. 1) Inst Biological Chemistry, Academia Sinica, Taipei, Taiwan; 2) Institute of Biochemical Sciences, National Taiwan University, Taipei, Taiwan. 218B Establishment of inter-muscular attachments requires the activity of Vestigial and DER signalling. Hua Deng1,2, John B. Bell2, Andrew J. Simmonds1. 1) Department of cell biology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada; 2) Department of Biological Sciences, Faculty of Science, University of Alberta, Edmonton, AB, Canada. 219C Characterization of an NFkB-mediated hematopoietic response to injury. Cory J. Evans, Amy McWhorter, Utpal Banerjee. Department of Molecular, Cell and Developmental Biology, UCLA, Los Angeles, CA 90095. 220A Repair of damaged 3’-ends of Drosophila DNA depends on TDP1 (GKT). Dongyu Guo1, Thomas Dexheimer2, Yves Pommier2, Howard Nash1. 1) NIMH, NIH, Bethesda, MD; 2) CCR, NCI, NIH, Bethesda, MD. 221B Identification of non-neuronal CO2 signaling pathway components using high throughput RNAi and small molecule screens. Iiro Taneli Helenius, Jacob I. Sznajder, Greg J. Beitel. Northwestern Univ, Evanston, IL.

222C Atg6, homolog of the tumor suppressor Beclin 1, functions in autophagy and endocytosis during development. Jahda H. Hill1, Louisa P. Wu1, Eric H. Baehrecke2. 1) Dept. of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD; 2) Dept. of Cancer Biology, University of Massachusetts Medical School, Worcester, MA. 223A A noncanonical role of septate junction proteins in the visceral mesoderm, essential for mesodermal closure in Drosophila. Yasuhito Kawakatsu, Takasi Okumura Okumura, Reo Maeda, Kiichirou Taniguchi, Naotaka Nakazawa, Kenji Matsuno. Tokyo university of science, noda, Japan. 224B Genetic interaction of POSH (Plenty of SH3 domains), a JNK signaling pathway scaffolding protein, and dmyc. Vicky Kuo. Biology, City College of New York, New York, NY. 225C Jabba mediates sequestration of histones on embryonic lipid droplets. Zhihuan Li, Michael Welte. Department of Biology, University of Rochester, Rochester, NY. 226A SNS Cytodomain Motifs and Potential Downstream Adaptors That Regulate Myoblast Fusion. Elspeth Pearce, Erin Katzfey, Susan Abmayr. Stowers Inst, Kansas City, MO. 227B DOA and MAP kinase signaling converge to regulate SRm160. Leonard Rabinow1, Yujie Fan1,2, Aryn Gittis1, Francois Juge3. 1) Univ Paris XI, CNRS UMR C8080, Orsay, 91140 France; 2) East China Normal University, School of Life Science, 200062 Shanghai People’s Republic of China; 3) Institut de Génétique Moléculaire, CNRS UMR 5535, 34293 Montpellier, France. 228C Genetic characterization of acal, a novel player in Drosophila embryonic dorsal closure and adult head formation. Luis Daniel Ríos-Barrera, Juan Rafael Riesgo-Escovar. Neurobiology Institute, Universidad Nacional Autónoma de México, Querétaro 76230, México. 229A A PTPome-wide analysis of Drosophila protein tyrosine phosphatases. Abirami Santhanam1,2, Dong-Yuan Chen1, Suh-Yuen Liang3, Hsueh-Yen Ku1, Guang-Chao Chen1,2, TzuChing Meng1,2. 1) Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan; 2) Taiwan International Graduate Program, Academia Sinica, Taipei Taiwan); 3) National Core Facility for Proteomic Research, Academia Sinica, Taipei, Taiwan. 230B Drosophila lysophospholipid acyltransferases are specifically required for germ cell development. Josefa Steinhauer1, Miguel Gijón2, Wayne Riekhof3, Dennis Voelker3, Robert Murphy2, Jessica Treisman1. 1) Dev Gen, Skirball Inst, New York Univ, New York, NY; 2) Dept of Pharmacology, University of Colorado Denver, Aurora, CO; 3) Dept of Medicine, Program in Cell Biology, National Jewish Health, Denver, CO.

48

POSTER SESSIONS Poster board number is in bold above the title. See page 15 for presentation schedule. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

231C Characterization of novel epidermal growth factor receptor target genes in Drosophila oogenesis. Lisa A. Kadlec, Jarrod Buzalewski, Justin Crawford, Michelle Junker. Department of Biology, Wilkes University, Wilkes-Barre, PA. 232A Retroactivity in a Developmental Signaling Network. Yoosik Kim1, Keisuke Ishihara1, Tsuyoshi Hirashima1, Gerardo Jiménez2, Ze’ev Paroush3, Stanislav Y. Shvartsman1. 1) Department of Chemical Engineering and Lewis-Sigler Institute for Integrative Genomics, Princeton University, NJ; 2) Institut de Biologia Molecular de Barcelona-CSIC and Institució Catalana de Recerca i Estudis Avançats, Parc Científic de Barcelona, Barcelona 08028, Spain; 3) Department of Developmental Biology and Cancer Research, Institute for Medical Research - Israel-Canada, The Hebrew University-Hadassah Medical School, PO Box 12272, Jerusalem 91120, Israel. 233B Which sites on the Drosophila insulin receptor mediate its role in growth regulation versus axon guidance? Caroline R. Li1, Dongyu Guo2, Julie Hou2, Leslie Pick1,2. 1) Program in Molecular and Cell Biology, University of Maryland, College Park, MD; 2) Department of Entomology, University of Maryland, College Park, MD. 234C Breathless Pathway Component Requirements in Branching Morphogenesis. Emily A. McMillan, Amin S. Ghabrial. Department of Cell and Developmental Biology, University of Pennsylvania, Philadelphia, PA. 235A The TF Lame duck is a direct target of ALK/jeb signaling pathway during muscle fusion in the trunk visceral mesoderm. Dmitry Popichenko, Ruth Palmer. Mol Biol Department, Univ Umea, Umea, Sweden. 236B EGFR regulates myoblast proliferation during adult myogenesis in Drosophila. Kumar Vishal, Krishan Badrinath, Sarah Elizabeth Bache-Wiig, Joyce Ferannades. Zoology, Miami Uuiversity, Oxford, OH. 237C Characterizing dominant enhancers of a trio mutant phenotype. Eric C. Liebl, Marcus J. Geer, Brian T. Lynch, Katie C. Palozola. Dept Biol, Denison Univ, Granville, OH. 238A dPak regulation of actomyosin contractility in the follicular epithelium during oogenesis. Stephanie Vlachos, Nicholas Harden. Molecular Biology & Biochemistry, Simon Fraser University, Burnaby, BC, Canada. 239B Maintaining osmotic homeostasis in gametes and their environment in the Drosophila female reproductive tract. Ido Apel1, Sandra L. Schnakenberg2, Mark L. Siegal2, Yael Heifetz1. 1) Department of Entomology, Hebrew University, Rehovot, Israel; 2) Department of Biology, New York University, New York, NY.

240C Wingless is released from secreting cells on exosome-like vesicles. Karen Beckett1, Solange Monier2, Roland Le Borgne2, Jean-Paul Vincent1. 1) National Institute for Medical Research, The Ridgeway, Mill Hill, London, NW7 1AA, United Kingdom; 2) CNRS UMR 6061, Université de Rennes 1, 2 avenue du Pr. Bernard, CS 34317, 35043 Rennes Cedex, France. 241A CrebA and its human homologs, Creb3L1 and Creb3L2, are major and direct regulators of secretory capacity. Rebecca M. Fox, Deborah J. Andrew. Dept Cell Biol, Johns Hopkins Univ, Baltimore, MD. 242B Earthbound Mediates Contextual Regulation of Wnt/Wingless Signaling by Promoting B-catenin/TCF Complex Formation. Hassina Benchabane1, Nan Xin1, Ai Tian1, Brian Hafler2, Kerrie Nguyen1, Yashi Ahmed1. 1) Dept Genetics, Dartmouth Medical School, Hanover, NH; 2) Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA. 243C Oligomeric State Determines the Role of CtBP as a Transcriptional Coactivator and Corepressor of Wingless Targets. Chandan Bhambhani, Ken Cadigan. Dept MCDB, Univ Michigan, Ann Arbor, MI. 244A Identification of tissue-specific components in the Wingless signaling pathway. Nan Xin, Hassina Benchabane, Ai Tian, Yashi Ahmed. Dept Gen, Dartmouth Med Sch, Hanover, NH. Cell cycle and checkpoints 245B Regulation of the Anaphase Promoting Complex (APC) in Drosophila female meiosis. Osamah Batiha, Alison Petrie, Andrew Swan. Department of Biology, University of Windsor. Windsor, ON. Canada. 246C Expression of Drosophila Chk2 leads to mid-oogenesis cell death in a p53-and caspase- independent manner. Anya Bakhrat1, Tracy Pritchett2, Kim McCall2, Uri Abdu1. 1) Life Sci, Ben Gurion Univ, Beersheba, Israel; 2) Department of Biology, Boston University, Boston, MA 02215 USA. 247A imp-B may act as a mediator between imp-A2 and kelch during Drosophila oogenesis and early embryogenesis. Sowjanya Kallakuri1, Tamás Szlanka1,2, Erika Virágh1,2, Istvan Kiss1,2, Bernard Mechler1. 1) German Cancer Research Centre, Developmental Genetics Department, A040, Heidelberg, INF581,Germany-69120; 2) Biological Research Centre, Hungarian Academy of Sciences,Department of Genetics,H-6720 Szeged, Hungary. 248B Characterizing the molecular link between the meiotic DNA damage checkpoint and the translational regulation of Gurken. Wei Li, Martha Klovstad, Trudi Schüpbach. HHMI/Department of Molecular Biology, Princeton University, Princeton, NJ 08544.

POSTER SESSIONS

49

Poster board number is in bold above the title. See page 15 for presentation schedule. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

249C Cell Cycle Regulation Via Inter-Nuclear Communication in Drosophila Melanogaster. Xuemin Lu, Jeff Drocco, David Tank, Eric Wieschaus. Molecular Biol Dept, Princeton Univ, Princeton, NJ. 250A Translational regulators dFMRP and Caprin control the cell cycle machinery at the midblastula transition. Ophelia Papoulas1, Kate Monzo1, Greg Cantin2, Cristian Ruse2, John R. Yates, III2, John C. Sisson1. 1) Section of MCD Biology, The Univ. of Texas at Austin, Austin, TX; 2) The Dept. of Chemical Physiology, The Scripps Research Institute, La Jolla, CA. 251B Detecting Common Fragile Sites in Drosophila. Matthew C. LaFave1, Lewis J. Overton2, Kelly A. Wolfe2, Jeff Sekelsky1,2. 1) Curriculum Gen/Molec Biol, Univ North Carolina, Chapel Hill, NC; 2) Department of Biology, University of North Carolina, Chapel Hill, NC. 252C Drosophila mus308 promotes alternative end-joining repair of DNA double-strand breaks. Mitch McVey, Sze Ham Chan, Amy Marie Yu. Dept. of Biology, Tufts University, Medford, MA. 253A Study of DNA replication in Drosophila using cell free in vitro system. Igor N. Chesnokov, Anton Svitin. Dept Biochem & Molec Gen, Univ Alabama, Birmingham, AL. 254B Characterization of Sld5, a Subunit of the Heterotetrameric GINS Complex. Catherine A. Gouge, Tim W. Christensen. Department of Biology, East Carolina Univ, Greenville, NC. 255C Understanding the Significance of the Mcm10-RecQ4 Interaction in Drosophila melanogaster. Chad M. Hunter. Department of Biology, East Carolina University, Greenville, NC. 256A The Threat of Re-Replication on Genome Integrity. Heidi S. Schindel1, Madhura Kadaba1, Sonam Mehrotra2, Brian R. Calvi1. 1) Indiana University, Bloomington, IN; 2) UMDNJ, Piscataway, NJ.

260B Pleiotropic effects of a Drosophila male sterile meiotic mutant. Silvia Volpi1, Silvia Bongiorni1, Barbara T. Wakimoto2, Giorgio Prantera1. 1) Dept. Agrobiology & Agrochemistry, Univ Tuscia, Viterbo, Italy; 2) Dept. of Biology, University of Washington, Seattle, USA.

Cell death 261C Investigating the role of engulfment genes in Drosophila developmental cell death. Christina K. McPhee1,2, Mary Logan3, Marc R. Freeman3, Eric H. Baehrecke1. 1) Dept Cancer Biol, Univ Massachusetts Med Sch, Worcester, MA; 2) Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD; 3) Howard Hughes Medical Institute, Department of Neurobiology, University of Massachusetts Medical School, Worcester, MA. 262A Role of autophagy and lysosome fusion genes in developmental nurse cell death in the ovary. Jeanne S. Peterson, Allison Timmons, Kim McCall. Dept Biol, Boston Univ, Boston, MA. 263B The possible role of NF-KB in autophagic cell death in salivary gland cell death. Qian Wang1, Adrienne L. Ivory2, Louisa P. Wu3. 1) Molecular and Cellular Biology, University of Maryland at College Park, College Park, MD; 2) Cell Biology and Molecular Genetics, University of Maryland at College Park, College Park, MD; 3) University of Maryland Biotechnology Institute, College Park, MD. 264C Roles of drICE and dcp-1 in naturally occurring cell death in the developing Drosophila optic lobe. Hiromi Akagawa, Yu Togane, Yusuke Hara, Rie Ayukawa, Keiichiro Hirai, Kengo Beppu, Tatsuro Enomoto, Takashi Takahashi, Hidenobu Tsujimura. Developmental Biology, Tokyo University of Agriculture and Technology, Fuchu, Tokyo 183-8509, Japan.

257B Defining the function of Dup (Cdt1) in DNA replication. Hua Zhong, MacKenzie Austgen, Brian R. Calvi. Biology, Indiana University, Bloomington, IN.

265A Caspase regulation and activity in Drosophila mid-oogenesis cell death. Adam P. Klein1, Mark Ditzel2, Pascal Meier3, Kim McCall1. 1) Department of Biology, Boston University, Boston, MA; 2) Institute of Genetics and Molecular Medicine, Edinburgh Cancer Research Centre, Edinburgh, UK; 3) The Breakthrough Toby Robins Breast Cancer Research Centre, Institute of Cancer Research, London, UK.

258C Fly Cyclin G, a regulator of cell growth and cell cycle. Floria Faradji, Sébastien Bloyer, Neel B. Randsholt, Frédérique Peronnet. Biologie du développement, UMR7622, CNRS, Université Pierre et Marie Curie, Paris, France.

266B The JNK pathway interacts with dpp signaling in the formation of head capsule. Sung-Yeon Park, Brian Stultz, Deborah Hursh. Division of Cellular and Gene Theraphies, CBER/FDA, Bethesda, MD20892.

259A Functional characterisation of a novel interaction partner of the cell cycle regulatory kinase Aurora-A. Thomas Kessler, Anne Kathrin Scholz, Johan Gobom, Eckhard Nordhoff, Hans Lehrach, Bodo Lange. Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Berlin, Germany.

267C Cell death and signals in the morphogenesis of the ovary. Laurent Théodore1,2, Thomas Rubin1, Fabienne Chalvet1, Nicolas Dos Santos1, Mathieu Bartoletti1, Jacqueline Leroy1. 1) Cell Memory, LGBC, Univ Versailles, CNRS UMR 8159, Versailles, France; 2) Université Paris Sud 11, 91405 Orsay France.

50

POSTER SESSIONS Poster board number is in bold above the title. See page 15 for presentation schedule. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

268A The complex interactions of Hippo signaling with the intrinsic cell death pathway in the regulation of Hippo-mediated cell death. Shlipi Verghese1, Shirani Gunashekere1, Lauren Scriappa1, Kieran Harvey4, Amit Singh1,2,3, Madhuri Kango-Singh1,2,3. 1) Department of Biology, University of Dayton, Dayton, OH; 2) Pre Med Program, University of Dayton, Dayton, OH; 3) Center for Tissue Regeneration and Engineering at Dayton, University of Dayton, 300 College Park Dayton, OH 45469; 4) Research Division, Peter MacCallum Cancer Centre St Andrew’s Place, East Melbourne VIC 3002. 269B Genetic analysis of ecdysone cascade in Drosophila optic lobe cell death. Yusuke Hara1,2, Yu Togane1,2, Hiromi Akagawa1, Takashi Takahashi1, Rie Ayukawa1, Keiichiro Hirai1, Kengo Beppu1, Tatsuro Enomoto1, Kikuo Iwabuchi2, Hidenobu Tsujimura1. 1) Developmental Biology, Tokyo Univ of Agri and Tech, Tokyo, Japan; 2) Applied Entomology, Tokyo Univ of Agri and Tech, Tokyo, Japan. 270C Mapping and expression analysis of persistent salivary gland (PSG) mutants. Robert Ihry, Yunsik Kang, Kevin Konieczko, Doug Braun, Arash Bashirullah. Sch Pharmacy, Univ Wisconsin, Madison, Madison, WI. 271A bulsa, a Novel Regulator of Programmed Cell Death During Metamorphosis. Yunsik Kang, Anne Sapiro, Robert Ihry, Arash Bashirullah. Sch Pharmacy, Univ Wisconsin, Madison, Madison, WI. 272B Regulating both apoptosis and proliferation by Hedgehog and Notch signaling. Audrey Christiansen, Tian Ding, Andreas Bergmann. Dept Biochemistry and Molecular Biology, UT MD Anderson Cancer Center, Houston, TX. 273C Molecular identification of the thread1 mutation using recombinant lines. Vishal K. Patel, Jeanne Peterson, Andrea Mislak, Kim McCall. Department of Biology, Boston University, Boston, MA. 274A HtrA2/Omi is involved in a noncanonical cell death program during normal elimination of germ cells in Drosophila. Eli Arama, Keren Yacobi-Sharon, Yuval Namdar. Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel. 275B Dual roles of Drosophila p53 in cell death and cell differentiation. Yun Fan1, Tom Lee1, Dongbin Xu1, Zhihong Chen1, AnneFrançoise Lamblin2, Hermann Steller3, Andreas Bergmann1. 1) Dept Biochem & Molec Biol, UT MD Anderson Cancer Ctr, Houston, TX; 2) U of Minnesota Interdisciplinary Informatics, OVPR, Saint Paul, MN; 3) Howard Hughes Medical Institute, The Rockefeller University, New York, NY.

276C Genetic Screens to Isolate Regulators of Apoptosis-Induced Compensatory Proliferation in Proliferating Drosophila Tissues. Shiuan Wang1,2, Yun Fan2, Andreas Bergmann1,2. 1) Program in Developmental Biology, Baylor College of Medicine, Houston, TX; 2) Department of Biochemistry & Molecular Biology, The University of Texas, MD Anderson Cancer Center, Houston, TX. 277A Apoptosis Regulation in Endocycling Cells. Bingqing Zhang1, Sonam Mehrotra2, Jhomar E. Marquez1, Brian R. Calvi1. 1) Department of Biology, Indiana University, Bloomington, IN; 2) Department of Radiation Oncology, CINJ-UMDNJ 195 Little Albany Street, New Brunswick, NJ,08903. 278B Daxx-like Protein Mediates Oxidative Stress- and UV-induced Apoptosis via JNK Signaling Pathway. Soojin Hwang, Yoon Seak Suh, Yoon Ki Hong, Gahee Choi, Seung Yeop Han, Kyoung Sang Cho. Konkuk University, Seoul, Korea. 279C The companion of reaper (corp) gene is a potent inducer of apoptosis. Christian W. Antonio1, Lei Zhou2, Yanping Zhang2, Rong Yuan2, Gina Chan2, Andreas Bergmann1. 1) Department of Biochemistry and Molecular Biology, Graduate Program in Genes and Development, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 1000, Houston, TX 77030, USA; 2) Department of Molecular Genetics and Microbiology, University of Florida, Gainesville, FL 32610-0232, USA.

Cell division and growth control 280A Identification of Novel Regulators of Cell Competition. Yassi Hafezi, Justin Bosch, Iswar Hariharan. Dept Molecular & Cell Biol, Univ California, Berkeley, Berkeley, CA. 281B Mahjong Involvement in Lgl-mediated Cell Competition. Yoichiro Tamori1, Yasuyuki Fujita2, Wu-Min Deng1. 1) Biological Science, Florida State University, Tallahassee, FL; 2) Cell and Developmental Biology, University College London, London, UK. 282C A Novel Role for dMyc in the Regulation of Organismal Growth and Metabolism. Federica Parisi1, Sara Riccardo1, Sheri Zola1, Carlina Lora1, Dalton Conley2, Daniela Grifoni3, Paola Bellosta1. 1) Biology, City College New York-CUNY, New York -NY; 2) Biology, NYU College of Arts and Science, New York -NY; 3) Biology, University of Bologna, BO -Italy. 283A Activated Stat92E behaves as a super-competitor. Aloma B. Rodrigues, Erika A. Bach. Dept Pharm, NYU Sch Med, New York, NY. 284B Cell cycle regulated phosphorylation and localization of Nuf, a Rab11 effector, may drive furrow formation in the Drosophila embryo. Justin M. Crest, William Sullivan. Dept MCD Biol, Univ California, Santa Cruz, CA.

POSTER SESSIONS

51

Poster board number is in bold above the title. See page 15 for presentation schedule. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

285C The molecular mechanism of Fwd function in Drosophila spermatocyte cytokinesis. Anya Cyprys1,2, Gordon Polevoy1, Julie Brill1,2. 1) Developmental and Stem Cell Biology Program, Hospital for Sick Children, Toronto, ON, CAN; 2) Department of Molecular Genetics, University of Toronto, Toronto, ON, CAN. 286A The role of the JAK/STAT pathway in control of proliferation. Tamara Reyes Robles, Aloma Rodrigues, Erika Bach. Pharmacology, New York University School of Medicine, New York, NY. 287B PiP(4,5)P2 regulates cortical dynamics in mitotic cells. Chantal Roubinet1,2, Barbara Decelle1, Gaetan Chicanne3, Bernard Payrastre3, François Payre2, Sebastien Carreno1. 1) IRIC , University of Montreal, Montreal, Quebec, Canada; 2) CBD, Université Toulouse III, UMR 5547, Toulouse, France; 3) Inserm U563, Université Toulouse III, Toulouse, France. 288C The role of Myb, a conserved DNA-binding protein, in cytokinesis. Heather Stalker, Joseph Lipsick. Departments of Genetics and Pathology, Stanford Univ, Stanford, CA. 289A Giant meiotic spindles in males from Drosophila species with giant sperm tails. Maurizio Gatti, Silvia Bonaccorsi, Ramona Lattao. Dept Gen & Molec Biol, Univ Rome La Sapienza, Rome, Italy. 290B Identification of Drosophila Meiotic MCM Proteins. Kathryn Kohl, Jeff Sekelsky. Univ North Carolina, Chapel Hill, NC. 291C Satellite DNA is associated with ring-Y-induced mitotic defects in lethal D. melanogaster embryos. Patrick M. Ferree, Daniel A. Barbash. Dept Molec Biol & Gen, Cornell Univ, Ithaca, NY. 292A Drosophila lin-52 is required for early embryonic development. Cuiyun Geng1, Debashis Sahoo1, Peter Lewis2, Michael Botchan2, Joseph Lipsick1. 1) Pathology and Genetics, Stanford University, Stanford, CA; 2) Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, CA. 293B Chromatin influences the restructuring of the mitotic spindle and cell shape. Shaila Kotadia, William Sullivan, Anne Royou. Molecular, Cell, and Developmental Biology, University of California Santa Cruz, Santa Cruz, CA. 294C The E1 SUMO activating enzyme is critical for cell proliferation in Drosophila. Kiriaki Kanakousaki1,2, Matthew C. Gibson1. 1) Stowers Inst Med Res, Kansas City, MO; 2) The Open University. 295A Functional analysis of CG7097 during Drosophila wing development. Martin D. Resnik-Docampo, Jose Felix de Celis. Centro de Biologia Molecular “Severo Ochoa”, Madrid, madrid, Spain.

296B Connecting Lar to Pak in the Drosophila egg chamber. Daniel T. Bergstralh, Daniel St. Johnston. Gurdon Inst, Univ Cambridge, Cambridge, United Kingdom. 297C Microtubule Depolymerizing Kinesin Klp10A Restricts Microtubule Growth in Drosophila Female Meiosis. Andrew Marc Harrison, Sarah J. Radford, Kim S. McKim. Waksman Institute and Department of Genetics, Rutgers, the State University of New Jersey, Piscataway, New Jersey 08854. 298A Characterization of New Meiotic Chromosome Segregation Mutants in Drosophila Females. Sarah J. Radford, Kim S. McKim. Waksman Institute, Rutgers University, Piscataway, NJ. 299B The Salvador-Warts-Hippo pathway in tissue regeneration. Felix A. Grusche1,2,3, Helena Richardson2,3, Kieran F. Harvey1,3. 1) Cell Growth and Proliferation Laboratory, Peter MacCallum Cancer Centre, Melbourne, Australia; 2) Cell Cycle and Development Laboratory, Peter MacCallum Cancer Centre, Melbourne, Australia; 3) University of Melbourne, Australia. 300C Polycomb regulation of the thor gene regulates growth of the imaginal discs. Heather Mason-Suares, Peter Harte. Dept. Genetics, Case Western Reserve Univ, Cleveland, OH. 301A Interkinetic nuclear movements during Drosophila wing disc cell proliferation. Emily J. Meyer, Matthew C. Gibson. Stowers Institute for Medical Research, Kansas City, MO, USA. 302B Temporal regulation of the Salvador-Warts-Hippo pathway in Drosophila eye development. Claire Milton, Xiaomeng Zhang, Nathaniel Albanese, Kieran Harvey. Research Division, Peter MacCallum Cancer Centre, East Melbourne, VIC, Australia. 303C A transgenic screen for novel regulators in wing growth and patterning. Neil J. Pearson, Epithelial Biology Department. CRUK London Reseasrch Institute, London, United Kingdom. 304A New genes functioning in Drosophila hematopoiesis. Kai Li Tan, Svetlana Minakhina, Ruth Steward. Rutgers University Molecular Biology and Biochemistry Waksman Institute Busch Campus Piscataway. NJ 08854. 305B The Drosophila Netrin Receptor Frazzled functions as a Tumor Suppressor during Development. Molly Duman-Scheel1,2. 1) Department of Medical & Molecular Genetics, Indiana University School of Medicine, South Bend, IN; 2) Department of Biological Sciences, Walther Cancer Institute, and Eck Institute for Global Health, University of Notre Dame, Notre Dame, IN. 306C Loss of the Retinoblastoma family protein (RBF) predisposes cells to dedifferentiation. Maxim Frolov, Brandon Nicolay. Biochem Molec Gen, Univ Illinois Chicago, Chicago, IL.

52

POSTER SESSIONS Poster board number is in bold above the title. See page 15 for presentation schedule. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

307A Slaughterhouse-five (Sfv) is a conditional growth suppressor that restricts organ size by targeting the Hippo tumor suppressor pathway. M. Melissa Gilbert1, Marla Tipping2, Alexey Veraksa2, Kenneth H. Moberg1. 1) Dept Cell Biology, Emory University, Atlanta, GA; 2) Dept Biology, University of Massachusetts, Boston, MA. 308B Dystroglycan Regulates the Extracellular Matrix and Cell Survival. Nicola Haines1,2, Waris Shah1, Bryan A. Stewart2, Salvatore Carbonetto1. 1) Centre for Research in Neuroscience, McGill University Health Center, Montreal, QC, Canada; 2) Department of Biology, University of Toronto, Mississauga, ON, Canada. 309C The archipelago tumor suppressor gene limits Rb/E2Fregulated apoptosis in an RTK-sensitive manner. Sarah C. Nicholson1, M. Melissa Gilbert1, Brandon, N. Nicolay2, Maxim, V. Frolov2, Kenneth, H. Moberg1. 1) Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322; 2) Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, IL 60607. 310A Phosphorylation-dependent and independent repression of Yorkie in Fat-Hippo signaling. Hyangyee Oh, B. V. V. G. Reddy, Ken Irvine. Howard Hughes Medical Institute, Waksman Institute and Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway NJ. 311B The apico-basal polarity proteins, Lgl, aPKC and Crumbs, regulate the Salvador/Warts/Hippo pathway through two distinct mechanisms to control tissue growth. Helena E. Richardson1, Nicola A. Grzeschik1, Linda M. Parsons1, Melinda L. Allott1, Kieran F. Harvey2. 1) Cell Cycle/Development,Res Div, Peter MacCallum Cancer Ctr, Melbourne, Australia; 2) Cell Growth/ Proliferation,Res Div, Peter MacCallum Cancer Ctr, Melbourne, Australia. 312C Rabex-5 negatively regulates Ras signaling to control growth and pattern formation in Drosophila. Hua Yan, Maryam Jahanshahi, Elizabeth Horvath, Hsiu-Yu Liu, Cathie Pfleger. Department of Oncological Sciences, Mount Sinai School of Medicine, New York, NY.

Chromatin and epigenetics 313A Assembly and function of Drosophila melanogaster centromeric chromatin in meiosis and development. Elaine Dunleavy, Gary Karpen. Department of Genome Dynamics, Lawrence Berkeley National Laboratory, Berkeley, CA. 314B HipHop interacts with HOAP and HP1 to protect Drosophila telomeres in a sequence—independent manner. Guanjun Gao1, Claude Walser Jean2, Michelle Beaucher1, Patrizia Morciano1, Natalia Wesolowska1, Jie Chen1, Yikang Rong1. 1) LBMB/NCI, Bethesda, MD; 2) LMCB, NIDDK, NIH, Bethesda, MD.

315C Analysis of the functional significance of the association of drosophila HP1 and dFACT complex in transcription. So Hee Kwon, Selene Swanson, Laurence Florens, Machael P. Washburn, Susan M. Abmayr, Jerry L. Workman. Workman Lab, Stower’s Institute for Medical Research, Kansas city, MO. 316A Yemanuclein-A, a functional partner of histone H3.3 chaperone HIRA, has an essential and specialized role in sperm chromatin remodelling at fertilization. Guillermo A. Orsi1, Régis Meyer2, Michèle Capri2, Ahmed Algazeery2, Pierre Couble1, Ounissa Aït-Ahmed2, Benjamin Loppin1. 1) Centre de Génétique Moléculaire et Cellulaire, UMR5534, Villeurbanne, France; 2) Institut de Génétique Humaine, CNRS UPR 1142, Montpellier, France. 317B Scaffold Attachment Factor A (SAF-A) characterization and localization in Drosophila melanogaster. John C. Aldrich, Keith A. Maggert. Department of Biology, Texas A&M University, College Station, TX. 318C Characterization of the Drosophila Scaffold Attachment Factor B (SAFB). Catalina Alfonso, Keith Maggert. Dept Biology, Texas A&M Univ, College Station, TX. 319A Spps, a Drosophila Sp1/KLF family member, binds to PREs and is required for PRE activity late in development. J. L. Brown, Judith Kassis. LMG/NIH, Bethesda, MD. 320B Role of Tip60 in APP mediated axonal arborization in Drosophila melanogaster. Keerthy Chandrasekar, Felice Elefant. Department of Biological Sciences, Drexel University, Philadelphia, PA 19104. 321C P[en] homing to the engrailed region of the genome. Yuzhong Cheng, Deborah Kwon, Judith Kassis. Lab Molecular Genetics, NICHD, Bethesda, MD. 322A Role of CTCF in the expression of the rDNA in Drosophila melanogaster. Paola A. Guerrero, Keith Maggert. Dept Biol, Texas A & M Univ, College Station, TX. 323B Identification of Mutations in Topoisomerase 2, a Protein Required for Somatic Pairing in Drosophila. Amber M. Hohl1,2, Morgan Thompson2, Jianhong Wu3, James Morris4, Tao Shih Hsieh3, C.-ting Wu2, Pamela K. Geyer1,5. 1) Graduate Program in Genetics, University of Iowa, Iowa City IA; 2) Department of Genetics, Harvard Medical School, Boston MA; 3) Department of Biochemistry, Duke University, Durham NC; 4) Department of Biology, Brandeis University, Waltham MA; 5) Department of Biochemistry, University of Iowa, Iowa City IA. 324C Influence of genomic context on chromatin patterns surrounding promoters and nucleosome-associated sequences. Sasha A. Langley1,2, Gary Karpen1,2. 1) Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, CA; 2) Department of Genome Dynamics, Lawrence Berkeley National Lab, Berkeley, CA.

POSTER SESSIONS

53

Poster board number is in bold above the title. See page 15 for presentation schedule. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

325A The rDNA is a regulator of chromatin balance. Silvana Paredes, Keith Maggert. Dept Biol, Texas A&M Univ, College Station, TX. 326B HipHop interacts with HOAP and HP1 to protect Drosophila telomeres in a sequence-independent manner. Yikang S. Rong. NCI/NIH, Bethesda, MD. 327C The histone acetyltransferase Tip60 plays an active role in controlling synaptic bouton formation at the Drosophila neuromuscular junction. Jessica Sarthi, Neetu Singh, Felice Elefant. Biological Sci, Drexel Univ, Philadelphia, PA. 328A Comparative Analysis of the Wanderer Genes Between the D. MELANOGASTER and D. VIRILIS Dot Chromosomes. Jeannette Wong, Wilson Leung, Chris Shaffer, Bio4342 Students, Sarah C. R. Elgin. Biology, Washington University in St. Louis, St. Louis, MO. 63130. 329B A potential role for DmelTip60 in axonal transport. Ashley A. Zervos, Felice Elefant. Dept Biol, Drexel Univ, Philadelphia, PA. 330C Characterization of DSB repair in heterochromatin. Irene Chiolo1, Ryan Kunitake2, Aki Minoda1, Serafin U. Colmenares1, Gary H. Karpen1,2. 1) Genome Biol, LBNL, Berkeley, CA; 2) MCB Dept, UCB, Berkeley, CA. 331A Flavors of heterochromatin: Identification of factors impacting sensitivity to repetitious element 1360. Kathryn L. Huisinga, Sarah C. R. Elgin. Dept. Biology, Washington Univ, St Louis, MO. 332B Cell-cycle-dependent binding of SUUR to Drosophila melanogaster polytene chromosomes. Tatiana D. Kolesnikova1, Darya S. Bebyakina2, Olga V. Posukh1, Evgenia N. Andreyeva1, Dmitri E. Koryakov1. 1) Inst Chemical Bioligy and Fundamental Medicine, Novosibirsk, Russia; 2) Bashkir State Pedagogical University, Ufa, Russia.

336C An evaluation of Drosophila Mcm10 conserved domains. Michael Reubens, Jen Apger, Tim W. Christensen. Department of Biology, East Carolina University, Greenville, NC. 337A Dynamic patterns of histone modifications and chromosomal proteins in Drosophila heterochromatin. Nicole C. Riddle, Akiko Minoda, Peter Kharchenko, Artyom Alekseyenko,Yuri B. Schwartz, Daniela Linder-Basso, Michael Tolstorukov, Andrey Gorchakov, Gregory Shanower, Mitzi Kuroda, Vincenzo Pirrotta, Peter Park, Sarah C. R. Elgin, Gary Karpen. modENCODE chromatin group. 338B Heterochromatin Protein 1a (HP1a) promotes an open chromatin structure between two divergently transcribed genes on chromosome 4. Michael W. Vitalini, Diane E. Cryderman, Lori L. Wallrath. Biochemistry, University of Iowa, Iowa City, IA. 339C STAT and heterochromatin protect genome stability. Shian-Jang Yan, Su Jun Lim, Anthony Scott, Song Shi, Pranabananda Dutta, Willis Li. Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY. 340A Heterochromatin protein 1 (HP1) family: Role in the Recognition of Double Strand Breaks in Drosophila melanogaster.Raghuvar G. Dronamraju, James M. Mason. Laboratory of Molecular Genetics, National Institute of Environmental Health Science, research Triangle Park, NC. 341B The Role of Histone H3K36 demethylase dKDM4A in Gene Transcription. Chia-Hui Lin, Ariel Paulson, Susan M. Abmayr, Jerry L. Workman. Stowers Institute for Medical Research, Kansas City, MO. 342C The use of epigenetic-based therapeutic drugs to investigate Tip60/AICD regulated transcription in Drosophila. Emily Mazanowski, Meridith Toth Lorbeck, Maria Lapchenko, Nikita Shah, Paul Donegan, Felice Elefant. Biology Dept, Drexel University, Philadelphia, PA.

333C The Role of CG7172 as a Putative Tumor Suppressor Gene. Su Jun Lim, Pranab Dutta, Willis Li. Biomedical Genetics, University of Rochester Medical Center, Rochester, NY.

343A Histone acetyltransferases in chorion gene amplification. Kristopher H. McConnell, Brian R. Calvi. Dept Biol, Indiana Univ, 1001 E Third St, Bloomington, IN 47405.

334A Divergent LHR orthologs have conserved properties of heterochromatin localization. Shamoni Maheshwari, Daniel Barbash. Dept Molec Biol & Gen, Cornell Univ, Ithaca, NY.

344B Genome-wide mapping of histone modifications and chromosomal proteins in Drosophila melanogaster. Akiko Minoda1, Peter Kharchenko2, Artyom Alekseyenko2, Nicole C. Riddle3, Yuri B. Schwartz4, Daniela Linder-Basso4, Michael Tolstorukov2, Andrey Gorchakov2, Gregory Shanower4, Mitzi Kuroda2, Vincenzo Pirrotta4, Peter Park2, Sarah C. R. Elgin3, Gary Karpen1, modENCODE chromatin group5. 1) Dept Genome Dynamics, Lawrence Berkeley Natl Lab, Berkeley, CA; 2) Dept. of Genetics, Harvard-Partners Center for Genetics & Genomics, Boston, MA; 3) Washington University / Dept Biology, St Louis, MO 63130; 4) Department of Molecular Biology and Biochemistry, Rutgers University , Piscataway, NJ; 5) USA.

335B SUUR copurifies with proteins involved in replication, DSB repair, cell cycle control, and heterochromatin maintenance. Olga Posukh1, Andrey Gorchakov1,2, Igor Zhimulev1. 1) Department of Molecular and Cellular Biology, Inst. of Chemical Biology and Fundamental Medicine, Novosibirsk, Russian Federation; 2) HHMI/ Harvard-Partners Center for Genetics and Genomics, Boston, MA, USA.

54

POSTER SESSIONS Poster board number is in bold above the title. See page 15 for presentation schedule. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

345C Tip60 HAT activity modulates APP function during Drosophila neuronal development. Meridith Toth, Felice Elefant. Dept Biol, Drexel Univ, Philadelphia, PA. 346A H2A.Z nucleosomes downstream of active gene promoters are homotypic. Christopher M. Weber1,2, Jorja G. Henikoff2, Steven Henikoff2,3. 1) Molecular and Cellular Biology Program, University of Washington, Seattle, WA; 2) Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA; 3) Howard Hughes Medical Institute, Seattle, WA. 347B Uncovering the interband nature. Maria B. Berkaeva1, Sergei A. Demakov1, Yuri B. Schwartz2, Igor F. Zhimulev1. 1) Dept Molecular and Cellular Biology, IChBFM SB RAS, Novosibirsk, Russian Federation; 2) Dept Molecular Biology and Biochemistry, Rutgers University, Piscataway, NJ, USA. 348C Identification and characterization of a barrier/insulator flanking an enhancer region in Drosophila. Nianwei Lin, Can Zhang, Lei Zhou. Dept Molecular Genetics & Microb, Univ Florida, Gainesville, FL. 349A WARI-mediated pairing-dependent repression within the apterous region. Martin Müller1, Daryl Gohl2,3, Paul Schedl3, Markus Affolter1. 1) Cell Biology, Biozentrum, Basel, Switzerland; 2) Department of Neurobiology, Stanford University, USA; 3) Department of Molecular Biology, Princeton University, USA. 350B Combinatorial binding of insulator proteins defines functional properties of associated chromatin insulator elements. Yuri B. Schwartz1, Peter Kharchenko2, Daniela Linder-Basso1, Michael Tolstorukov2, Andrey Gorchakov2, Akiko Minoda3, Gregory Shanower1, Artyom Alekseyenko2, Nicole C. Riddle4, Huabing Li1, Sarah Gadel4, Cameron Kennedy3, Sarah Marchetti4, Sarah C. R. Elgin4, Mitzi Kuroda2, Peter Park2, Gary Karpen3, Vincenzo Pirrotta1. 1) Dept. of Molecular Biology and Biochemistry, Rutgers University, Piscataway, NJ; 2) Harvard Medical School, Boston, MA; 3) Dept. Genome Dynamics, Lawrence Berkeley Natl. Lab, Berkeley, CA; 4) Depart. of Biology, Washington University, St. Louis, MO. 351C Exploring the Chromatin Landscape of a Molecularly Defined Telomere. Michelle L. Beaucher, Xiao-Feng Zheng, Yikang Rong. LBMB, NCI/NIHI, Bethesda, MD. 352A Rapid evolution of the mu2 gene. James M. Mason1, Raghuvar Dronamraju1, Rachelle Bienstock2. 1) Lab Molecular Genetics, NIH/NIEHS, Research Triangle Park, NC; 2) Scientific Computing Lab, NIH/NIEHS, Research Triangle Park, NC.

355A Clones mutant for polyhomeotic, a Polycomb Group gene, form ectopic endocrine glands that induce non-autonomous cell overproliferation. Siqian Feng1,2, Jianhua Huang2, Jian Wang1,2. 1) Program in Molecular and Cell Biology; 2) Department of Entomology, University of Maryland, College Park, Maryland 20742. 356B The Genetic and Biochemical Analysis of Su(z)2 Function. Son C. Nguyen1, Nicole Francis2, Chao-ting Wu1. 1) Dept of Genetics, Harvard Medical School, Boston, MA; 2) Dept of Molecular and Cellular Biology, Harvard University, Cambridge, MA. 357C Genome-wide patterns of alternative acetylation or trimethylation of histone H3K27 depend on an antagonistic balance between TrxG and PcG proteins. Feng Tie, Peter Scacheri, Peter Harte. Dept Genetics, Case Western Reserve Univ, Cleveland, OH. 358A The CHD1 chromatin remodeling factor alters global chromosome structure. Jennifer A. Armstrong, Lakshmi V. Bugga, Eugenie S. Hong, Rebecca Edwards, Devna Mangrola, Kelsey A. Schmidt. Joint Sci Dept, Claremont Colleges, Claremont, CA. 359B Alternative splicing of NURF301 generates distinct NURF chromatin remodeling complexes with altered modified histone binding specificities. Paul W. Badenhorst, So Yeon Kwon. School of Immunity & Infection, Institute of Biomedical Research, Edgbaston, United Kingdom. 360C Autoregulation of the large noncoding roX1 RNA gene to target chromatin modifications of the Drosophila male X chromosome. Chiat Koo Lim, Richard Kelley. Baylor College of Medicine, Houston, TX. 361A Mining functional DNA elements in the Drosophila genome. Per Stenberg1,2. 1) Molecular Biology, Umeå University, Umeå, Sweden; 2) Computaional Life Science Cluster (CLiC), Umeå University, Umeå, Sweden.

Drosophila models of human diseases 362B Glial regulation of behavioral responses to ethanol exposure. Fred W. Wolf1, Nasima Mayer2, Roland J. Bainton2, Eric C. Kong1. 1) Ernest Gallo Clinic and Research Center, Emeryville, CA; 2) Department of Anesthesia, University of California, San Francisco.

353B Mapping Tel using P element induced male recombination. Hemakumar M. Reddy, James M. Mason. Laboratory of Molecular Genetics, NIH/NIEHS, Research Triangle Park, NC.

363C Transgenic Drosophila for modeling environmental arsenic toxicity and pathology. Iain L. Cartwright1, Junjun Shang1, Jorge Muñiz Ortiz2. 1) Dept Molec Gen, Univ Cincinnati Col Med, Cincinnati, OH; 2) NHEERL, EPA, Research Triangle Park, NC.

354C Functional dissection of PRE transcribed non-coding RNAs. Daniel Enderle, Christian Beisel, Renato Paro. ETHZ, D-BSSE, Basel, Basel, Switzerland.

364A Heritability of Variable Toxicity Post Chemotherapy Treatment. Galina Dvorkina, Maura Murphy, Mahtab Jafari, Anthony Long. Ecology & Evolutionary Biol, Univ California, Irvine, CA.

POSTER SESSIONS

55

Poster board number is in bold above the title. See page 15 for presentation schedule. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

365B Functional Characterization of tumor suppressor Birt-HoggDubé (BHD) gene in Drosophila melanogaster. Kriti Gaur, Jinghong Li, Amy Tsurumi, Dakun Wang, Guan Wu, Willis Li. University of Rochester, 601 elmwood avenue, rochester, NY 14642. 366C Genetic identification of novel components of receptor tyrosine kinase down-regulation pathways in Drosophila melanogaster. Noor Hossain, Enio Polena, Roger Jacobs. Biol Dept, McMaster U, Hamilton, ON, Canada. 367A Investigation of how RasACT cooperates with RhoGEF2 overexpression and scribble mutants in tumourigenesis. Peytee Khoo, Anthony Brumby, Helena Richardson. Cell Cycle and Development, Peter McCallum Cancer Institute, East Melbourne, Victoria, Australia. 368B Structure and Function Analysis of Merlin and Merlin Interacting Proteins. Albert C. Leung1, Andrew J. Simmonds2, Sarah C. Hughes1. 1) Medical Genetics, University of Alberta, Edmonton, Alberta, Canada; 2) Cell Biology. 369C The Drosophila ortholog of WWOX tumor suppressor has functional interactions with superoxide dismutase. Louise V. O’Keefe, Alex Colella, Sonia Dayan, Qingwen Chen, Amanda Choo, Robert Richards. School of Molecular and Biomedical Science, The University of Adelaide, Adelaide, SA, Australia. 370A Analysis of human xpd mutations in Drosophila melanogaster. Karin Stettler, Beat Suter. Institute of Cell Biology, Bern, Bern, Switzerland.

375C Mutations in Prickle homologues cause seizures in flies, mice and humans. J. Robert Manak1, Levi Sowers2, Hirotaka Tao3, Naoto Ueno3, Jeffrey D. Axelrod4, Alex Bassuk2. 1) Dept Biol, Univ Iowa, Iowa City, IA; 2) Dept Pediatrics, Univ Iowa, Iowa City, IA; 3) Div Morphogen, Nat Inst Basic Biol, Okazaki, Japan; 4) Dept Pathol, Stanford Univ Sch of Med, Stanford, CA. 376A Kismet regulates axonal pruning and migration, learning/ memory, and locomotion in a Drosophila model of CHARGE Syndrome. Daniel R. Marenda1,2, David Melicharek1, Sukhdeep Singh1, Laura Ramirez1, Rhea Thompson1. 1) Dept. of Biology, Drexel University, Philadelphia, PA; 2) Dept. of Neurobiology and Anatomy , Drexel University College of Medicine, Philadelphia, PA. 377B Hazy and Orthodenticle cooperate for photoreceptor cell function and morphogenesis. Monalisa Mishra, Ashwini Oke, Zachary Plummer, Qunfeng Dong, Cindy Lebel, Andrew Zelhof. dept ofBiology, Indiana University, Bloomington, IN. 378C Cultured Drosophila Neurons Reveal Neurotoxicity of Commonly Prescribed Drugs. Linda L. Restifo1,2, Cayla Baynes1, Robert Kraft1. 1) Department of Neuroscience, University of Arizona, Tucson, AZ; 2) Department of Neurology, Arizona Health Sciences Center, Tucson, AZ. 379A Evaluation of the genotoxic potential of diverse extracts of Tecoma stans in the somatic cells of Drosophila melanogaster. Marco A. Carballo. Laboratorio de Genética, Facultad de Ciencias, UNAM, Ciudad de México, México.

371B Interaction between RasV12 and scribble clones induces tumor development in Drosophila. Ming Wu, José Pastor-Pareja, Tian Xu. Dept Genetics, Yale Univ, New Haven, CT.

380B Regulation of energy stores and feeding by neuronal and peripheral CREB activity in Drosophila. Kanae Iijima-Ando1, Koichi Iijima2. 1) Lab of Neurogenetics and Pathobiology, Farber Inst Neurosciences, Thomas Jefferson Univ, Philadelphia, PA; 2) Lab of Neurodegenerative and Metabolic Diseases, Farber Inst Neurosciences, Thomas Jefferson Univ, Philadelphia, PA.

372C Modeling Degenerative Disc Disease in Drosophila. Joseph A. Chiaro, Hemlata Mistry. Department of Biology, One University Place, Widener University, Chester, PA 19013.

381C Genetically Manipulated ER stress produces Drosophila Diabetic Models. Kyu-Sun Lee, Kweon Yu. Aging Res Ctr, KRIBB, Daejeon, 305-806, Korea.

373A Influence of genes nAchR-30D, Cam, slit and robo on manifestation of mutant dystrophin phenotype in Drosophila melanogaster. Nataliya Holub, Yulya Shalovylo, Daria Maksymiv, Yaroslava Chernyk. Department of Genetics & Biotechnology, Ivan Franko National University of Lviv, Hrushevsky St, 4, 79005 Lviv, Ukraine.

382A Development of Type II Diabetes in Drosophila melanogaster. Siti Nur Sarah Morris, Bilal Fawaz, Johannes Bauer. Biological Sciences, Southern Methodist University, Dallas, TX.

374B ATP7 of Drosophila is involved in Ras-extracellular signalrelated kinase signaling. Oky Maeng1,2, Wonseok Son2, Ook-Jun Yoo2, Young-Ha Lee1, Guang-Ho Cha1. 1) Dept. of Infection Biology, College of Medicine, Chungnam National University , Daejeon, Korea; 2) Dept. of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, Korea.

383B A fly model of cell stress underlying neonatal diabetes. SooYoung Park1, Michael Ludwig2, Calvin Williams2, Honggang Ye1, Natalia Tamara1, Graeme Bell1, Martin Kreitman2. 1) Dept, of Medicine, University of Chicago, Chicago, IL; 2) Dept. of Ecology & Evolution University of Chicago Chicago IL 60637. 384C Developing Drosophila melanogaster as a model for aminoglycosidic antibiotic toxicity. Alicia R. Martin, Celeste A. Berg. University of Washington, Seattle, WA.

56

POSTER SESSIONS Poster board number is in bold above the title. See page 15 for presentation schedule. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

385A Characterization of B-amyloid properties in treated Drosophila models of Alzheimer’s disease. Jim Mediatore, Jimmy Symonds, Alfred T. Villaluz, Marianna O. Foos, Emily Lund, Devin Keefe, Marie E. Fitzpatrick, Lenard Diggins, Phil O’Neil, Matt B. Mahoney, Carol M. Singh. Vitruvean LLC, Watertown, MA. 386B Mutations in the Mitochondrial Methionyl-tRNA Synthetase Cause Neurodegeneration in Drosophila and Humans. Vafa Bayat1,2, Manish Jaiswal3, Taraka Donti3, Zhihong Li3, Claire Haueter4, Brett Graham3, Hugo Bellen1,3,4,5. 1) Developmental Biology Program, Baylor College of Medicine, Houston, TX; 2) Medical Scientist Training Program, Baylor College of Medicine, Houston, TX; 3) Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX; 4) Howard Hughes Medical Institute, Baylor College of Medicine, Houston, TX; 5) Department of Neuroscience, Baylor College of Medicine, Houston, TX. 387C The role of Microtubule Associate Proteins in progressive neurodegeneration. Bonnie J. Bolkan, Doris Kretzschmar. CROET, L606, Oregon Hlth & Sci Univ, Portland, OR. 388A Identification of a Drosophila melanogaster functional ortholog of human HspB8 and analysis of Dm-HspB8 and h-HspB8 implication in protein folding diseases. Serena Carra, Alessandra Boncoraglio, Bart Kanon, Jeanette Brunsting, Ody Sibon, Harm Kampinga. Cell Biology, University Medical Center Groningen, Groningen, Groningen, Netherlands. 389B Largescale genetic screen in Drosophila to identify novel regulators of Parkinson’s disease genes. Caroline P. Fernandes, Yong Rao. Centre for Research in Neuroscience and Department of Biology, McGill University Health Centre, Montreal, Canada. 390C Investigation of the role of TDP-43 in motor neuron function and neurodegeneration. Dennis Hazelett, Judy Stewart, Archana Thomas, David Morton. Integrative Biosci, OHSU, Portland, OR. 391A Hsp70 and Hsp90 Contribute to the Proteasomal Degradation of TPIsugarkill . Stacy L. Hrizo1,2, Fortuna O. Arumeni2, Michael J. Palladino2. 1) Biology, Slippery Rock University, Slippery Rock, PA; 2) Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA. 392B Role of TATA-box Binding Protein (TBP) in PolyQ Mediated Neurodegenerative Diseases: Implication of Transcription Dysfunction. Tun-Chieh Hsu, Chun-Yen Yang, Ming-Tsan Su. Department of Life Science, National Taiwan Normal University, Taipei, Taiwan. 393C Exposure to Fungal volatile organic compounds cause loss of expression of dopaminergic neurons in Drosophila melanogaster.Arati A. Inamdar, Edward Mark, Shweta Mehra, Prakash Masurekar, Joan Bennett. Rutgers University, New Brunswick, NJ 08901.

394A The Mechanism of ER stress induced Apoptosis in Drosophila. Min-Ji Kang, Jaehoon Chung, Hyung Don Ryoo. Dept Cell Biol, New York Univ Sch Med, New York, NY. 395B Effects of the immunophilin FKBP52 in a Drosophila model of Alzheimer’s beta-amyloid toxicity. Mary Konsolaki1, Weihuan Cao1, Reiko Sanokawa-Akakura2, Raymond Birge2. 1) Dept Genetics, Rutgers, The State University of NJ, Piscataway, NJ; 2) Department of Biochem and Mol Biol, University of Medicine and Dentistry of New Jersey, Newark, NJ. 396C Drosophila as a model for RNA mediated dominant expanded repeat disease. Kynan Lawlor, Catherine McLeod, Louise O’Keefe, Saumya Samaraweera, Clare van Eyk, Robert Richards. School of Molecular and Biomedical Sciences, University of Adelaide, Adelaide, SA, Australia. 397A Genetic Basis of Cell Death in Neurodegeneration in Alzheimer’s Disease. Rohan M. Modi1,2, Jaison J. Nainaparampil1,2, Pedro Fernandez-Funez3, Amit Singh1,2,4. 1) Premedical Program, University of Dayton, 300 College Park Drive, Dayton, OH; 2) Department of Biology, University of Dayton, 300 College Park Drive, Dayton, OH; 3) Department of Neurology, L3-100 McKnight Brain Institute, Newell Drive, Gainesville, FL. 32610; 4) Center for Tissue Regeneration and Engineering at Dayton (TREND), University of Dayton, 300 College Park Drive, Dayton, OH. 398B ATM inactivation in Drosophila causes neurodegeneration through altered expression of cell cycle, germline, and innate immunity genes. Andrew Petersen, Stacey Rimkus, David Wassarman. University of Wisconsin-Madison, Madison, WI. 399C Sequence-Dependent Prion protein Misfolding and Neurotoxicity. Jonatan Sanchez-Garcia1, Yan Zhang1, Diego E. Diego E.1,2, Diego E. Diego E.1. 1) Department of Neurology, University of Florida, Gainesville, FL, 32610; 2) Department of Neurology, UTMB, Galveston, TX 77555. 400A Small quinone-tryptophan molecules rescue Alzheimer’s disease model. Daniel Segal1, Roni Scherzer-Attali1, Dorit Farfara2, Anat Frydman-Marom1, Michal Levy-Sakin1, Sivan Peled1, Tali Benromano2, Dan Frenkel2, Ehud Gazit1. 1) Molecular Microbiol & Biotech, Tel Aviv Univ, Tel Aviv, Israel; 2) Neurobiology, Tel Aviv Univ, Tel Aviv, Israel. 401B The Therapeutic Effects of Resveratrol in an Alzheimer’s Model. Kalebi C. Shayo, Binh Pham, Nicole BourniasVardiabasis. Biology Department, Cal State San Bernardino, San Bernardino, CA. 402C Histological and biochemical validation of neurodegenerative disease models in Drosophila. Alfred T. Villaluz, Emily A. Lund, Jim Symonds, Marianna Foos, James Mediatore, Lenard T. Diggins, Phil O’Neil, Matt B. Mahoney, Carol M. Singh. Vitruvean, LLC, Watertown, MA.

POSTER SESSIONS

57

Poster board number is in bold above the title. See page 15 for presentation schedule. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

403A Tws, a regulatory subunit of PP2A, acts independently of Pink1 to promote apoptosis through mitochondrial fragmentation and oxidative stress. Yu-Chun Wang. Department of Life science, National Taiwan Normal University, Taipei 11677, Taiwan, ROC.

410B The Dynamic Localization of Polycystin-2 homolog (Amo) During Spermatogenesis in Drosophila testis. Weizhe Li, Kristy Chu, Stacey Cook, Michael Kottgen, Terry Watnick. Nephrology, Johns Hopkins University School of Medicine, Baltimore, MD.

404B The role of chaperones in a fly model of a human neurodegenerative disease. John M. Warrick, John Daniel, Paul Hargarten. Dept Biol, Univ Richmond, Richmond, VA.

411C Ubc9-dependent modulation of NF-KB-dependent inflammation in Drosophila. Indira Paddibhatla1,2, Mark . J. Lee1, Roberto Ferrarese1, Marta. E. Kalamarz1,2, Shubha Govind1,2. 1) Biol Dept, City Col New York, New York, NY; 2) The Graduate Center, The City College of the City University of New York,.

405C Crag is required for long term light adaptation. Bo Xiong1, Vafa Bayat1,2, Manish Jaiswal3, Shinya Yamomoto1, Ke Zhang4, Hector Sandova3, Wu-Lin Charng1, Xiao Shi1,2, Adeel Jawaid3, Claire Haueter5, Yong-Qi Lin5, Hugo Bellen1,3,5,6. 1) Program in Developmental Biology; 2) Medical Scientist Training Program; 3) Department of Molecular and Human Genetics,; 4) Program in Structural and Computational Biology and Molecular Biophysics; 5) Howard Hughes Medical Institute; 6) Department of Neuroscience, Baylor College of Medicine, Houston, TX. 406A B-methylamino-L-alanine Induces Chronic Neurotoxicity in Drosophila. Shaoyun Zang1, Xianchong Zhou1, Wilfredo Escala3, Spyridon Papapetropoulos4,5, Grace Zhai1,2. 1) Molecular and Cellular Pharmacology, University of Miami, Miami, FL; 2) Neuroscience Program, Miller School of Medicine, University of Miami, Miami, FL; 3) University of Miami Bridges to the Future Program, Miami Dade Honors College, Miami, Florida 33132, USA; 4) Department of Neurology, University of Miami School of Medicine, Miami, Florida 33136, USA; 5) Present address: Biogen Idec Inc, Cambridge, Massachusetts, USA. 407B Characterization of a novel gene related to Leigh syndrome. Ke Zhang1, Manish Jaiswal2, Shinya Yamamoto3, Vafa Bayat3, Bo Xiong3, Hector Sandoval2, Wu-lin Charng3, Xiao Shi3,4, Adeel Jawaid2, Yong Lin5, Clair Haueter5, Hugo Bellen1,2,3,5,6. 1) Program in Structural and Computational Biology and Molecular Biophysics,; 2) Department of Molecular and Human Genetics; 3) Program in Developmental Biology; 4) Medical Scientist Training Program; 5) Howard Hughes Medical Institute; 6) Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030. 408C The ER stress transcription factor XBP1s protects against Amyloid-beta neurotoxicity. Yan Zhang1, Jonatan SanchezGarcia1, Kurt Jensen1, Sergio Casas-Tinto1, Diego RinconLimas2, Pedro Fernandez-Funez1. 1) Dept of Neurology, University of Florida, Gainesville, FL; 2) Dept of Neurology, UTMB, Galveston, TX. 409A Diaphanous mutations disrupt auditory cytoskeleton. Frances L. Hannan1, Hima Ammana1, Peter O’Brien1, Cynthia Schoen2, Sarah Emery3, Margit Burmeister2,4, Marci M. Lesperance3. 1) Cell Bio, New York Med Col, Valhalla, NY; 2) Mol Behav Neuro, Univ Mich Ann Arbor, MI; 3) Oto-HNS, Univ Mich Ann Arbor, MI; 4) Hum Gen, Psych, Univ Mich Ann Arbor, MI.

412A dCASK plays a role in locomotion in Drosophila melanogaster. Justin Slawson, Elena Kuklin, Eugene Kim, Lilly Ostrovsky, Leslie Griffith. Biology, Brandeis University, Waltham, MA. 413B Modeling Spinal Muscular Atrophy in Drosophila. David L. Van Vactor1, Howard Chang1, Doug Dimlich1, April Duckworth1, Vasanthi Sridhar1, Tudor A. Fulga1, Mark Kankel1, Anindya Sen1, Ashim Mukherjee1, Melanie Smith1, Takakazu Yokokura1, Maria Dimitriadi2, Amy K. Walker2, Anne C. Heart2, Spyros Artavanis-Tsakonas1. 1) Dept Cell Biol/Neuroscience, Harvard Med Sch, Boston, MA; 2) Dept of Neuroscience, Brown University, Providence , RI. 414C Notch Signaling: A Role in Survival of Drosophila during Chronic Hypoxia. DeeAnn W. Visk1, Dan Zhou2, Mary Hsiao2, Gabriel G. Haddad2,3. 1) Division of Biology, University of California, San Diego, La Jolla, CA; 2) Department of Pediatrics, School of Medicine, University of California, San Diego, La Jolla, CA; 3) Rady Children’s Hospital, San Digeo, CA. 415A Conferring oxidant resistance in Drosophila melanogaster: role of JNK cascade. Huiwen W. Zhao1, Dan Zhou1, Victor Nizet1,2,4, Steven A. Wasserman3, Gabriel G. Haddad1,4. 1) Dept Pediatrics, Univ California, La Jolla, CA; 2) The Skaggs School of Pharmacy and Pharmaceutical Sciences, Univ California, La Jolla, CA; 3) Section of Cell and Developmental Biology, Univ California, La Jolla, CA; 4) Rady Children’s Hospital, San Diego, CA. 416B Metabolic Adaptation to Chronic Hypoxia in Drosophila melanogaster. Dan Zhou1, Sameh Ali3, Mary Hsiao1, Jin Xue1, Laura Dugan3, Gabriel Haddad1,2,4. 1) Dept Pediatrics, Univ Califonia, San Diego, La Jolla, CA; 2) Dept Neurosciences, Univ California, San Diego, La Jolla, CA; 3) Dept Medicine, Univ California, San Diego, La Jolla, CA; 4) Rady Children’s Hospital-San Diego, San Diego, CA. 417C Drosophila Agnostic Locus Bearing a Gene for LIMK1: From Heterochromatin Via Non-Coding RNAs to Complex Behavior. Ekatherina Nikitina, Anna Medvedeva, Alexandr Zhuravlev, Elena Savvateeva-Popova. Dept Neurogenetics, Pavlov Inst Physiology, St Petersburg, Russian Federation.

58

POSTER SESSIONS Poster board number is in bold above the title. See page 15 for presentation schedule. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

Evolution and quantitative genetics 418A Convergent duplication and subfunctionalization of armadillo/ B-catenin during insect evolution. Riyue Bao1, Markus Friedrich1,2. 1) Department of Biological Sciences, Wayne State University, 5047 Gullen Mall, Detroit, MI; 2) Department of Anatomy and Cell Biology, Wayne State University, School of Medicine, 540 East Canfield Avenue, Detroit, MI. 419B Evolutionary analysis of the bag of marbles gene elucidates both intraspecific function and the consequences of interspecific divergence. Heather A. Flores, Daniel A. Barbash, Charles F. Aquadro. Dept Molec Biol & Gen, Cornell Univ, Ithaca, NY. 420C Shavenbaby shadow enhancers contribute to phenotypic robustness. Nicolas Frankel1, Gregory Davis2, Diego Vargas1, Shu Wang1, François Payre3, David Stern1. 1) Howard Hughes Medical Institute and Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ, USA; 2) Department of Biology, Bryn Mawr College, Park Science Building, 101 N. Merion Ave, Bryn Mawr, PA, USA; 3) Centre de Biologie du Développement, UMR5547, Bat IVR3, 118 route de Narbonne, Toulouse, France. 421A Evolution of the Rhomboid Enhancer RhoBAD and Oenocyte Specification in Drosopholids. Lisa M. Gutzwiller, Kevin A. Burns, Brian Gebelein. Dev Biol, Cincinnati Children’s Hosp, Cincinnati, OH. 422B Evolution of the Hox gene fushi tarazu in arthropods. Alison Heffer1, Jeffrey Shultz2, Leslie Pick1,2. 1) Prog. in Molecular and Cell Biology; 2) Dept Entomology, Univ Maryland, College Park, MD. 423C Evolution of Enhancer Position in the Drosophila yellow Gene. Gizem Kalay1, Patricia Wittkopp1,2. 1) MCDB Dept, University of Michigan, Ann Arbor, MI; 2) EEB Dept, University of Michigan, Ann Arbor, MI. 424A Conserved and divergent wing vein patterning mechanisms in the red flour beetle Tribolium castaneum. Tingjia Lao1,2, Padmapriyadarshini Ravisankar1,2, Yoshinori Tomoyasu1. 1) Department of Zoology, Miami University, Oxford, OH; 2) cofirst author. 425B Identification of candidate genes for a methylmercury tolerance trait. Cecon T. Mahapatra1, Jeffrey Bond2, David M. Rand3, Matthew D. Rand1. 1) Anatomy and Neurobiology, University of Vermont, Burlington, VT; 2) Department of Microbiology and Molecular Genetics, Bioinformatics Core, College of Medicine, University of Vermont; 3) Department of Ecology & Evolutionary Biology, Brown University, Providence, RI.

426C Highly dynamic cell behavior during early development in the intermediate germ insect Gryllus bimaculatus, as revealed by analyses of transgenic embryos. Taro Mito1, Taro Nakamura2, Masato Yoshizaki1, Tetsuya Bando1, Hideyo Ohuchi1, Sumihare Noji1. 1) Life Systems, The University of Tokushima, Tokushima, Tokushima, Japan; 2) Venture Business Laboratory, The University of Tokushima, Tokushima, Tokushima, Japan. 427A Systematic analysis of BMP signaling dynamics across Drosophila species during oogenesis. Matthew G. Niepielko1, Jitendra S. Kanodia2, Nir Yakoby1. 1) Dept Biol and Center for Computational and Integrative Biol, Rutgers University, Camden, NJ 08102; 2) Dept Chem Eng and Lewis Sigler Institute, Princeton University, Princeton NJ 08544. 428B Expression pattern evolution of retroduplicated genes in Drosophila species. Ryan S. O’Neill, Denise V. Clark. Biology Department, University of New Brunswick, Fredericton, New Brunswick, Canada. 429C Convergent duplication and subfunctionalization of armadillo/Bcatenin during insect evolution. Bao Riyue, Friedrich Markus. Department of Biological Sciences, Wayne State University, Detroit, MI. 430A Lineage-specific isoform duplication of an alternatively spliced gene within the genus Drosophila, Galpha49B. Kawther Abdilleh, Sarah R. Moore, Cristian I. Castillo-Davis. Dept. of Biology, University of Maryland, College Park, MD. 431B Functional characterization of DPLGs, transposase-derived genes, in Drosophila. Esther Betran, Daniel Szalay, Cedric Feschotte. Department of Biology, University of Texas Arlington, Arlington, TX. 432C Genome-wide assessment of allelic gene conversion in Drosophila melanogaster using population genomics data. Claudio Casola1, Carrie Ganote2, Matthew Hahn1,2. 1) Department of Biology, Indiana University, Bloomington, IN; 2) School of Informatics and Computing, Indiana University, Bloomington, IN. 433A Study of function of two nuclear transport retrogenes (Dntf-2r and Ran-like) in relation to sex chromosome evolution. Susana Domingues, Mansi Motiwale, Esther Betrán. University of Texas at Arlington, Arlington, TX. 434B Examination of piRNA pathway evolution using D. melanogaster and D. simulans interspecific hybrids. Erin Kelleher, Daniel Barbash. Dept Molec Biol & Gen, Cornell Univ, Ithaca, NY. 435C Analysis of non-autonomous mobile elements of the retrovirus type without LTRs of the Clade I DMRT super family in the Drosophila virilis species group. Alex M. Kulikov, Oleg E. Lazebny. Dept Genetics, Koltsov Inst Dev Biology/RAS, Moscow, Russian Federation.

POSTER SESSIONS

59

Poster board number is in bold above the title. See page 15 for presentation schedule. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

436A Transpositionally active episomal hAT transposable elements. David A. O’Brochta1, Christina D. Stosic2, Kristina Pilitt1, Ramanand A. Subramanian1, Robert H. Hice2, Peter W. Atkinson2,3. 1) Center for Biosystems Research University of Maryland Biotechnology Institute Rockville, MD; 2) Department of Entomology University of California Riverside, CA; 3) Institute for Integrative Genome Biology, University of California Riverside, CA. 437B Open reading frame length polymorphisms within Drosophila melanogaster. Josephine A. Reinhardt1, David J. Begun2, Corbin D. Jones1. 1) Dept Biol, Univ North Carolina, Chapel Hill, NC; 2) Dept Ecology and Evolution, Univ California, Davis, CA. 438C Adaptive Impact of the Chimeric Gene Quetzalcoatl in Drosophila melanogaster. Rebekah L. Rogers1, Trevor Bedford2, Ana M. Lyons1, Daniel L. Hartl1. 1) Organismic & Evol Bio, Harvard Univ, Cambridge, MA; 2) Department of Ecology and Evolutionary Biology University of Michigan, Ann Arbor, MI.

445A Transposition efficiencies of P elements in Drosophila melanogaster: FP element vs. KP element. Masanobu Itoh1,2, Kazushi Miyatake1, Aki Yamamoto1. 1) Dept Applied Biol, Kyoto Inst Tech, Kyoto, Japan; 2) Insect Biomedical Research Center, Kyoto Inst Tech, Kyoto, Japan. 446B Spatial Variation of Sex-Biased Gene Expression in Drosophila willistoni. Richard Meisel, Andrew Clark. Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY. 447C The contribution of the Y chromosome to interspecific divergence of gene expression in Drosophila. Timothy Sackton, Daniel Hartl. Organismic & Evol Bio, Harvard Univ, Cambridge, MA.

439A Ultra-fine scale recombination intensity estimation in D. melanogaster. Nadia Singh, Charles Aquadro, Andrew Clark. Molec Biol & Gen, Cornell Univ, Ithaca, NY.

448A In situ localization of the Dras1 gene on the polytene chromosomes of sibling species and hybrids between them of the Drosophila virilis species group. Anna I. Chekunova1, Helen S. Zelentsova2, George N. Bakhtojarov1, Larisa N. Gause1, Vyacheslav G. Sergienko1, Alex M. Kulikov1, Svetlana Yu. Sorokina1, Vladimir G. Mitrofanov1. 1) Dept Genetics, Koltsov Inst Dev Biol, RAS, Moscow, Russian Federation; 2) Dept of Molecular Mechanisms of Biological Adaptation, Engelhadt Institute of Molecular Biology Russian Academy of Sciences,Moscow, Russian Federation.

440B Complete mitochondrial genome sequence of D. littoralis (Diptera: Drosophilidae) in aspect of Drosophila virilis species group phylogeny. Svetlana Y. Sorokina1, Boris V. Andrianov2, Vladimir G. Mitrofanov1. 1) Koltsov Inst Dev Biology, Moscow, Russian Federation; 2) Vavilov Inst General Genet, Moscow, Russian Federation.

449B Investigating the Relationship between Intron Size and Phylogenetic Distance in Drosophila species. Stacey Lytle1, Alexis Nagengast2, Justin DiAngelo3, Robert Morris1,2, Bruce Grant1. 1) Dept Biology; 2) Dept Biochemistry, Widener University, Chester, PA; 3) Dept Neuroscience/HHMI, University of Pennsylvania School of Medicine, Philadelphia, PA.

441C The evolution of heteromorphic sex chromosomes in mosquitoes. Melissa A. Toups, Matthew W. Hahn. Biology, Indiana University, Bloomington, IN.

450C From endemism to cosmopolitanism: the evolutionary history of the Afrotropical drosophilid, Zaprionus indianus, a new invader of the Palearctic Region and the Americas. Amir Yassin. Sackler Institute for Comparative Genomics, American Museum of Natural History, New York, NY.

442A The molecular evolution of inversion breakpoints in Drosophila pseudoobscura. Andre Wallace, Stephen Schaeffer. Dept Biol, The Pennsylvania State Univ, 208 Mueller Lab, University Park, PA. 16802. 443B Sex peptide is required for the release of stored sperm in mated Drosophila females. Frank W. Avila1, Kritipati Ravi Ram1, Margaret Bloch Qazi1,2, Mariana F. Wolfner1. 1) Dept Mol Biol & Gen, Cornell Univ, Ithaca, NY; 2) Dept Biol, Gustavus Adolphus College, Saint Peter, MN. 444C Fine-scale recombination rate variation within Drosophila melanogaster. Josep M. Comeron1,2, Ramesh Ratnappan1, Samuel S. Bailin1. 1) Department of Biology, University of Iowa, Iowa City, IA; 2) Roy J. Carver Center for Genomics, University of Iowa.

451A Natural Variation in Olfactory Receptor Neuron Response. J. Roman Arguello, Andrew Clark. Molec Biol & Gen, Cornell, Ithaca, NY. 452B A neutrality test free of equilibrium assumptions for TE insertions. Justin P. Blumenstiel1, Miaomiao He2, Casey M. Bergman2. 1) Ecology and Evolutionary Biology, University of Kansas, Lawrence, KS; 2) Faculty of Life Sciences, Computational and Evolutionary Biology, University of Manchester, Manchester, UK. 453C The roles of mutation and selection on copy number variation: lessons from two fly genomes. Margarida Cardoso-Moreira1, J. J. Emerson2, Andrew G. Clark1, Manyuan Long3. 1) Dept Molecular Biology and Genetics, Cornell University, Ithaca, NY; 2) Genomics Research Center, Academia Sinica, Taipei, Taiwan; 3) Dept Ecology & Evolution, University of Chicago, Chicago, IL.

60

POSTER SESSIONS Poster board number is in bold above the title. See page 15 for presentation schedule. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

454A Parasitoids and the pleiotropic effects of natural variation in Dopa decarboxylase on fitness in Drosophila melanogaster. Theresa K. Delaney1, Kate Laskowski2, Jeff Leips1. 1) Department of Biological Sciences, University of Maryland Baltimore County, Baltimore, MD; 2) Department of Animal Biology, University of Illinois, Urbana, IL. 455B Population genomics of transposable elements in Drosophila melanogaster. Anna-Sophie Fiston-Lavier, Mikhail Lipatov, Kapa Lenkov, Josefa González, Dmitri A. Petrov. Biology, Stanford University, Stanford, CA. 456C Adaptive Response of Drosophila melanogaster to P Element Invasion. Grace Y. C. Lee1,2, Charles H. Langley1,2. 1) Center for Population Biology, University of California, Davis, Davis, CA; 2) Department of Evolution and Ecology, University of California, Davis, Davis, CA. 457A Genetic variation in social preference depends on population context in Drosophila melanogaster. Julia B. Saltz1,2. 1) Dept Population Biol, Univ California, Davis, Davis, CA; 2) Molecular and Computational Biology, Univ of Southern California, Los Angeles, CA. 458B Population genetics using NGS of pooled samples. Christian Schlotterer1, Andreas Futschik2, Pablo Orozco1, Robert Kofler1, Viola Nolte1. 1) Inst Population Gen, Wien, Austria; 2) Inst. Statistics, Univ. Wien, Austria. 459C DDT association study confirms recent, repeated adaptive evolution of the cytochrome p450 Cyp6g1. Joshua Schmidt, Robert Good, Charles Robin. Genetics Department, The University of Melbourne, Melbourne, Australia. 460A Copy number variation within 39 high-quality Drosophila melanogaster whole-genome assemblies. Daniel R. Schrider1,2, Kristian Stevens3,4, Matthew W. Hahn1,2, Charles H. Langley3,4. 1) Department of Biology, Indiana University, Bloomington, IN; 2) School of Informatics and Computing, Indiana University, Bloomington, IN; 3) Department of Evolution and Ecology, University of California Davis, Davis, CA; 4) Center for Population Biology, University of California Davis, Davis, CA. 461B Female D. melanogaster harbor significant genetic variation for reduction in immune resistance due to mating. Sarah M. Short, Brian P. Lazzaro. Field of Genetics and Development, Cornell University, Ithaca, NY. 462C Hidden genetic variation in the ability of repair of fate map shift caused by 6 copies of bcd gene in a natural population. Kentaro M. Tanaka1, Aya Takahashi1,2, Masanobu Itho3, Toshiyuki Takano-Shimizu1,2,4,5. 1) Department of Genetics, Graduate University for Advanced Studies, Mishima, Japan; 2) Department of Population Genetics, National Institute of Genetics, Mishima, Japan; 3) Department of Applied Biology, Kyoto Institute of Technology, Kyoto, Japan; 4) Department of Biosystems Science, Graduate University for Advanced Studies, Hayama, Japan; 5) Department of Biological Science, Graduate School of Science, University of Tokyo, Japan.

463A Clusters of mutation and linkage disequilibrium. Ronny C. Woodruff. Dept Biol Sci, Bowling Green State Univ, Bowling Green, OH. 464B Genetic basis for natural variation in fecundity in Drosophila melanogaster. Alan O. Bergland1, Anne Genissel2, Sergey Nuzhdin3, Marc Tatar1. 1) Dept Ecology & Evolution, Brown Univ, Providence, RI; 2) Section of Ecology and Evolution, UC Davis, Davis, CA; 3) Molecular and Computational Biology,USC, Los Angeles, CA. 465C Body size variations and flight adaptations in altitudinal populations of Drosophila kikkawai from Indian subcontinent. Veer Bhan. Department of Biotechnology, University Institute of Engineering & Technology, M. D. University, Rohtak, Haryana, India. 466A Genetic divergence of life history traits in outdoor field cage and laboratory populations of Drosophila melanogaster. Veer Bhan. Department of Biotechnology, University Institute of Engineering & Technology, M D University, Rohtak, Haryana, India. 467B Antagonistic chemosensory responses to ethanol in Drosophila melanogaster. Kultaran S. Chohan1, Robert R. H. Anholt1,2, Trudy F. C. Mackay1. 1) Genetics, North Carolina State University, Raleigh, NC; 2) Biology, North Carolina State University, Raleigh, NC. 468C Male x Female Interactions in Drosophila Sperm Competition: SP x SPR. Clement Y. Chow, Mariana F. Wolfner, Andrew G. Clark. Dept Molec Biol & Gen, Cornell Univ, Ithaca, NY. 469A The influence of diet and reproduction on genetically based variation in lifespan and immune response. Mary F. Durham, Jeff Leips. Biological Sciences, University of Maryland, Baltimore County, Baltimore, MD. 470B Quantitative genetic mapping of natural variation in the posterior lobe of the genital arch within Drosophila melanogaster. Casey L. McNeil, Stuart J. Macdonald. Molecular Biosciences, University of Kansas, Lawrence, KS. 471C Causes and consequences of metabolic fitness in D. melanogaster. Kristi L. Montooth, Luke A. Hoekstra. Dept Biol, Indiana Univ, Bloomington, IN. 472A Age-Specific Genetic Variation Influencing Quantitative Traits in Drosophila melanogaster. Adrienne M. Starks, Jeff Leips. Biological Sciences, UMBC, Baltimore, MD. 473B Effect of Hsp genes on canalization and developmental stability. Kazuo H. Takahashi1, Siu F. Lee2, Lea Rako2, Ary A. Hoffmann2, Toshiyuki Takano-Shimizu3. 1) Okayama University, Okayama, Okayama, Japan; 2) Centre for Environmental Stress and Adaptation Research , The University of Melbourne, Melbourne, Australia; 3) Department of Population Genetics, National Institute of Genetics, Mishima, Shizuoka, Japan.

POSTER SESSIONS

61

Poster board number is in bold above the title. See page 15 for presentation schedule. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

474C Gynandromorph symmetry: Evidence for a developmental homeostasis drive? James N. Thompson, Clayton N. Hallman. Dept Zoology, Univ Oklahoma, Norman, OK. 475A Partial behavioral isolation between DDT resistant populations and their unselected controls under long term selection and isolation in Drosophila melanogaster. Patricia K. Arenson, Jazlen Samboy, Kylee Yam, Phillip T. Barnes. Biology Department, Connecticut College, New London, CT. 476B The evolution of gene regulation in the sensory system and brain of the female fly. Rita M. Graze1,2, Lauren M. McIntyre1,2,5, Bradley J. Main4, Marta L. Wayne3,2, Sergey V. Nuzhdin4. 1) Molecular Genetics and Microbiology, UF, Gainesville, FL; 2) Genetics Institute, UF, Gainesville, FL; 3) Department of Zoology, UF, Gainesville, FL; 4) Molecular and Computational Biology, USC, Los Angeles, CA; 5) Department of Statistics, UF, Gainesville, FL. 477C Reinforcement of Gametic Isolation in Drosophila. Daniel R. Matute1, Jerry A. Coyne2. 1) Ecology and Evolution, University of Chicago, Chicago, IL; 2) University of Chicago, Chicago, IL. 478A Adaptive changes in Drosophila santomea associated with a new habitat. Ramesh Ratnappan1, Ana Llopart1,2, Josep M. Comeron1,2. 1) Department of Biology, University of Iowa, Iowa City, IA; 2) Roy J. Carver Center for Genomics, University of Iowa, IA.

Gametogenesis and organogenesis 479B The Drosophila dosage compensation complex binding sites are enriched with a new, non-described, sequence motif. Miguel Gallach Caballero1, Vicente Arnau2, Ignacio Marín3. 1) Department of Biology. University of Texas - Arlington. USA; 2) Departamento de Informática. Universidad de Valencia. Spain; 3) Instituto de Biomedicina de Valencia. Consejo Superior de Investigaciones Científicas. Spain. 480C The repressive mechanism of the MSL complex in dosage compensation. Lin Sun, Harvey Fernandez, James Birchler. Biological Sci Div, Univ Missouri, Columbia, Columbia, MO. 481A Mipp1 is involved in Drosophila tracheal tube size and branch migration regulation. Yim Ling Cheng, Deborah Andrew. Cell Biology, Johns Hopkins School of Medicine, Baltimore, MD. 482B Tracheal Development in Drosophila eye. Wei-Chen Chu1,2, Yuan-Ming Lee1,3, Yi Henry Sun1,2,3. 1) Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan; 2) Graduate Institute of Life Sciences, National Defense Medical Center, Taipei, Taiwan; 3) Department of Life Sciences and Institute of Genome Sciences, National Yang Ming University, Taipei, Taiwan.

483C The metal ion transporter Malvolio is required for proper salivary gland invagination in Drosophila embryos. Rika Maruyama, Deborah Andrew. Dept Cell Biol, Johns Hopkins Sch Med, Baltimore, MD. 484A Cloning and characterization of sidewinder, a gene required for tracheal morphogenesis and septate junction function. Molly M. McGraw, Bethany G. Lucas, Liang Zhang, Robert Ward. Dept Molecular Biosciences, Univ Kansas, Lawrence, KS. 485B Notch and Wingless signaling regulate Cut levels and the balance between proliferation and differentiation of airway progenitors in Drosophila. Chrysoula Pitsouli1, Norbert Perrimon1,2. 1) Dept Gen, Harvard Med Sch, Boston, MA; 2) Howard Hughes Medical Institute. 486C Investigating the role of Crumbs and other polarity proteins in tracheal tube length control. Renée M. Robbins, Greg J. Beitel. Biochemistry, Molecular Biology, and Cell Biology, Northwestern University, Evanston, IL. 487A The role of Zpr1 in tracheal terminal cell lumen formation. Oscar E. Ruiz, Mark M. Metzstein. Dept Human Genetics, Univ Utah, Salt Lake City, UT. 488B A screening strategy to identify genes responsible for postembryonic heart development and function. Maik Drechsler, Achim Paululat. Department of Zoology/Developmental Biology, University of Osnabrueck, Osnabrueck, Germany. 489C The non-redundant role of the integrin binding sites of talin in integrin-mediated adhesion. Stephanie J. Ellis, Mary Pines, Ari Franco-Cea, Michael J. Fairchild, Sylvia T. Y. Cheung, Guy Tanentzapf. Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, BC, Canada. 490A The Actin Binding Domain and the Dimerization Motif of Talin are required for its function in Drosophila melanogaster embryonic muscles. Ari Franco-Cea, Michael Fairchild, Sylvia Cheung, Stephanie Ellis, Lin Yuan, Guy Tanentzapf. Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, British Columbia, Canada. 491B Syndecan is required for cardiac cell polarisation and lumen formation during Drosophila Cardiogenesis. Tanya F. Mahmood, Candice Soldaat, Martin Komosa, Katherine Moyer, Luz de Lourdes Vazquez Paz, J. Roger Jacobs. Biology, McMaster University, Hamilton, Ontario, Canada. 492C The Drosophila claudin Kune-kune is required for septate junction organization and tracheal tube size control. Kevin S. Nelson1, Mikio Furuse2, Greg J. Beitel1. 1) Dept. of Biochemistry, Molecular Biology, and Cell Biology, Northwestern University, Evanston, IL, USA; 2) Division of Cell Biology, Kobe University Graduate School of Medicine, Kobe, Japan.

62

POSTER SESSIONS Poster board number is in bold above the title. See page 15 for presentation schedule. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

493A Drosophila Src42 has an instructive role in tracheal tube size control and acts downstream of the lumenal extracellular matrix. Kevin S. Nelson, Greg J. Beitel. Dept of BMBCB, Northwestern University, Evanston, IL. 494B Regeneration and maintenance of basement membranes in the larva requires COPII-mediated secretion of Collagen IV by the fat body. Jose C. Pastor-Pareja, Tian Xu. Dept. Genetics, Yale University-HHMI, New Haven, CT. 495C Receptor Guanylyl Cyclase Gyc76C mediates integrindependent adhesion at myotendinous junctions. Unisha B. Patel, Monn Monn Myat. Dept Cell & Developmental Biol, WMC of Cornell Univ, New York, NY.

503B Search for and analysis of new fusion-relevant genes during the muscle development of Drosophila melanogaster. Bettina Bonn1, Gabor Daum2, Detlev Buttgereit1, Renate RenkawitzPohl1. 1) Developmental Biology, Philipps-Universität Marburg, Marburg, Hessen, Germany; 2) Faculty of Bio Sciences, Heidelberg University, Heidelberg, Germany. 504C Requirement of Mib2 for the correct development of Drosophila adult muscles. Marta Carrasco-Rando, Mar Ruiz-Gómez. Centro de Biología Molecular Severo Ochoa, CSIC, UAM, Madrid, Spain. 505A Identification of Mechanisms Regulating Muscle Size and Shape. Krista C. Dobi, Mary K. Baylies. Dept Dev Biol, SloanKettering Inst, New York, NY.

496A Shaping tissue morphogenesis through differential regulation of integrin-mediated adhesion, signalling and turnover. Mary K. Pines, Ari Franco-Cea, Michael J. Fairchild, Ellen Ryu, Guy Tanentzapf. Cellular and Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.

506B Specification of muscle identity in Drosophila: A genetic screen. Laurence Dubois, Jean-Louis Frendo, Johnatan Enriquez, Hadi Boukhatmi, Michele Crozatier, Alain Vincent. CNRS, centre de biologie du développement, toulouse, toulouse, France.

497B Dynamic shape changes of ECM-producing cells drive morphogenesis of ball-and-socket joints in the fly leg. Reiko Tajiri, Shigeo Hayashi. RIKEN Ctr DevelopmentalBiology, Kobe, Japan.

507C Three ways of screening to identify new genes in myoblast fusion. Verena Groth, Jing Kou, Yvonne Roger, Renate Renkawitz-Pohl, Susanne-Filiz Önel. Philipps-Universität Marburg, Marburg, Hessen, Germany.

498C Integrins are required for Slit and Robo localization during assembly of the Drosophila heart. Luz de Lourdes Vazquez Paz, Allison MacMullin, Jessica Vanderploeg, Roger Jacobs. Biology, McMaster University, Hamilton, Ontario, Canada.

508A RAW modulates JNK Signaling during Embryonic Gonad Morphogenesis. Jennifer C. Jemc, Mark Van Doren. Dept Biol, Johns Hopkins Univ, Baltimore, MD.

499A Hrp48 Attenuates Sxl Expression to Allow for Proper Notch Expression and Signaling in Wing Development. Offer Gerlitz1, Yaron Suissa1, Yossi Kalifa2, Tama Dinur1, Girish Deshpande3, Paul Schedl3. 1) Developmental Biology and Cancer Research, IMRIC, The Hebrew University-Hadassah Medical School, Jerusalem, Israel; 2) Department of Molecular Genetics Weizmann Institute of Science Rehovot Israel; 3) Department of Molecular Biology, Princeton University, Princeton, NJ 08540, USA. 500B Larval translucida (ltl) is a novel feedback regulator of DPP/ BMP signaling during Drosophila wing disc development. Milan Szuperak, Sally Salah, Emily Meyer, Aissam Ikmi, Matthew Gibson. Stowers Inst Med Res, Kansas City, MO. 501C Identification and characterization of genes regulated by Broad at the onset of metamorphosis in leg imaginal discs. Xiaochen Wang, Elspeth Pearce, Robert Ward. Dept Molec Biosci, Univ Kansas, Lawrence, KS. 502A Rac1 is required for myoblast migration during adult myogenesis in Drosophila. Krishan Badrinath, Joyce Fernandes. Dept Zoology, Miami Univ, Oxford, OH.

509B Forward mutagenesis screen reveals novel genetic loci required for muscle morphogenesis. Victoria K. Kalasinsky1, Thomas J. Metzger1, Mu Xu1, Mary K. Baylies2. 1) Weill Cornell Graduate School of Medical Sciences, New York, NY; 2) Sloan Kettering Institute, New York, NY. 510C Imaging and genetic analysis of Drosophila myogenic fusion mutants. Kate M. Rochlin, Mary Baylies. Dept Dev Biol, Sloan-Kettering Inst, New York, NY. 511A The role of terminal filament precursor number and ovarian mediolateral axis length in generating ovariole number. Didem P. Sarikaya, Cassandra Extavour. Organismic and Evolutionary Biology, Harvard Universtiy, Cambridge, MA. 512B Identification of novel components regulating Drosophila hematopoiesis. Jiwon Shim1,2, Cory Evans1,2, Tanya Hioe1, Jesse Zaretsky1, Utpal Banerjee1. 1) Mol Cell and Dev Biology, UCLA, Los Angeles, CA; 2) These authors contributed equally to this work. 513C The testes of Drosophila melanogaster are surrounded by multinucleated smooth muscles. Loreen Susic, Christina Hornbruch, Renate Renkawitz-Pohl. Developmental Biology, Philipps-Universität, Marburg, Hessen, Germany.

POSTER SESSIONS

63

Poster board number is in bold above the title. See page 15 for presentation schedule. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

514A Analysis of epithelial sheath muscle cell proliferation and development. Akemi J. Tanaka, Lynn Cooley. Department of Genetics, Yale School of Medicine, New Haven, CT 06520. 515B Myogenesis in wing hearts. Markus Tögel1,2, Christine Lehmacher1, Günther Pass2, Achim Paululat1. 1) Department of Zoology/ Developmental Biology, University of Osnabrueck, Osnabrueck, Germany; 2) Department of Evolutionary Biology, University of Vienna, Vienna, Austria. 516C Elucidating the role of a Drosophila insulator protein in the female germline. Ryan M. Baxley1, Alexey A. Soshnev1, Amber M. Hohl2, Michael W. Klein3, Aaron Liao3, Pamela K. Geyer1,2,3. 1) Molecular and Cellular Biology Program, University of Iowa; 2) Genetics Program, University of Iowa; 3) Biochemistry Department, University of Iowa, Iowa City, IA. 517A Protein Interaction Networks During Eggshell Assembly. Jessica M. Beauchamp, Gail Waring. Biological Sciences, Marquette University, Milwaukee, WI. 518B How to achieve the perfect centrosome number? Ines Bento, Mónica Bettencourt-Dias. Cell Cycle Regulation Lab, Instituto Gulbenkian de Ciência, Oeiras, Portugal. 519C Nutrient Stress Affects Polarized Protein Transport in the Drosophila Ovary. Katherine M. Burn1, Yuko Shimada2, Lynn Cooley1. 1) Gen, Cooley Lab, Yale Sch Med NSB388, New Haven, CT; 2) University of Tsukuba, 1-1-1 Tennoudai 3058572 Tsukuba, Ibaraki 305-8572 Japan. 520A The effect of clueless mutations on germcell mitochondria. Rachel T. Cox, Aditya Sen, Vanessa T. Damm. Dept. of Biochemistry and Molecular Biology, Uniformed Services University, Bethesda, MD. 521B ECR/USP mediates a ligand-regulated gate for tissue-specific chorion gene amplification. Leonard L. Dobens, Jennifer Hackney, Bridget Biersmith. School of Biological Sci, Univ Missouri-Kansas City, Kansas City, MO. 522C A role for Cyclin J in oogenesis revealed by interactions with the piRNA pathway. Russell L. Finley1,2, Govindaraja Atikukke2, Huamei Zhang1, Dongmei Liu1. 1) Ctr Molecular Med & Gen, Wayne State Univ Med Sch, Detroit, MI; 2) Department of Biochem. & Mol Biol, Wayne State Univ Med Sch, Detroit, MI. 523A Hypoxia Transiently Sequesters Mps1 and Polo to CollagenaseSensitive Filaments in Drosophila Prometaphase Oocytes. William D. Gilliland1,2, Dana L. Vietti2,3, Nicole M. Schweppe2,4, Fengli Guo2, Teri J. Johnson2, R. Scott Hawley2,5. 1) Depaul University, Chicago, IL; 2) Stowers Institute for Medical Research, Kansas City, MO; 3) University of Kansas Medical Center, Kansas City, KS; 4) Kansas City University of Medicine and Biosciences, Kansas City, MO; 5) Dept. of Physiology, University of Kansas Medical Center, Kansas City, KS.

524B Investigating the molecular function of A-Endosulfine and Early Girl in Drosophila female meiosis. Min-Young Kim, Daniela Drummond-Barbosa. Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD. 525C Translational regulation at oocyte maturation, egg activation, and the onset of embryogenesis in Drosophila. Iva Kronja, Terry Orr-Weaver. Whitehead Institute for Biomedical Research, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA. 526A Myosin Phosphatase and Incomplete Cytokinesis during Drosophila Female Germline Cyst Formation. SengKai Ong, Change Tan. Bond Life Sciences Center, Biological Sci, Uni Missouri-Columbia, Columbia, MO. 527B Quantitative analysis of epithelial folding during dorsal appendage morphogenesis. Miriam Osterfield1, Eric Wieschaus2,3, Trudi Schüpbach2,3, Stanislav Shvartsman1. 1) Lewis-Sigler Inst, Princeton Univ, Princeton, NJ; 2) Dept. Mol Biol, Princeton Univ, Princeton, NJ; 3) HHMI. 528C Tubulogenesis: Revealing the fundamental morphogenic mechanisms of tube formation. Nathaniel Peters1,2, Celeste Berg1,2. 1) Genome Sciences Department, University of Washington, Seattle, WA; 2) Molecular and Cellular Biology Program, University of Washington, Seattle, WA. 529A New lawc mutation exclusively affects oogenesis in Drosophila melanogaster. Olga B. Simonova, Julia Vorontsova, Roman Cherezov. Genetics of Morphogenesis, Koltzov Institute of Developmental Biology, Moscow, Russian Federation. 530B The Drosophila phosphatidylinositol 4-kinase IIIA is required for actin organization, polarity, and cell cycle control during oogenesis. Julie Tan1,2, David Hipfner3, Julie Brill1,2. 1) Prog Dev & Stem Cell Biol, Hosp Sick Children, Toronto ON, Canada; 2) Mol Genetics, Univ of Toronto, Toronto ON, Canada; 3) Instit de Recherches Clin de Montréal, Montréal QC, Canada. 531C Somatic versus germline roles of prostaglandins during oogenesis. Tina L. Tootle, Alexander Hubb. Anatomy and Cell Biology, University of Iowa, Carver College of Medicine, Iowa City, IA. 532A Investigation of Ribosomal Protein L10Ab function in Shrimp and Drosophila. Monwadee Wonglapsuwan1,2, Wilaiwan Chotigeat2, Kim McCall1. 1) Department of Biology, Boston University, Boston, MA; 2) Department of Molecular Biology and Bioinformatics, Faculty of Science, Prince of Songkla University, Thailand. 533B A mutation in uncle donald results in male and female sterility marked by germline cell loss. Qiao Zhang, Michael Buszczak. Department of Molecular Biology, UT Southwestwern Medical Center, Dallas, TX.

64

POSTER SESSIONS Poster board number is in bold above the title. See page 15 for presentation schedule. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

534C Phosphoproteomic Studies of Egg Activation in Drosophila melanogaster. Amber R. Krauchunas, Mariana F. Wolfner. MBG, Cornell Univ, Ithaca, NY. 535A Counting ovarioles: the role of nuclear BTB factors. Laurent Théodore1,2, Thomas Rubin1, Fabienne Chalvet1,2, Mathieu Bartoletti1, Nicolas Dos Santos1, Emilie Poisot1, Jacqueline Leroy1, Delphine Cumenal3, Frédérique Peronnet3. 1) Cell Memory, LGBC, Université Versailles, CNRS UMR 8159, Versailles, France; 2) Université Paris Sud 11, 91405 Orsay France; 3) UMR7622 - Biologie du Développement CNRS - UPMC Bâtiment C - 7ème étage - case 24 9, quai SaintBernard 75005 - Paris, France. 536B Dac and Dll interact with each other in leg to wing transdetermination. Alexander M. Tseng, Matt Becker, Anne Sustar, Gerold Schubiger. University of Washington, Seattle, WA. 537C Rho GTPase and DAAM regulate collective migration of the embryonic salivary gland. Na Xu. Dept Cell & Dev Biol, Weill Med Col Cornell, New York, NY. 538A Jak-STAT regulation of germ cell sex determination. Gretchen H. McConnell, Tigist Tamir, Thomas M. FitzGibbon, Carla Wood, Matthew Wawersik. Dept Biol, College William & Mary, Williamsburg, VA. 539B Sexual Compatibility Between the Germline And Soma of the Drosophila Testis. Sheryl Southard, Mark Van Doren. Johns Hopkins University, Baltimore, MD. 540C The role of doublesex in development of somatic sexual identity. Cale Whitworth, Mark Van Doren. Dept Biol, Johns Hopkins Univ, Baltimore, MD. 541A Sex-biased gene expression in the embryonic soma. Emily Clough, Renhua Li, Leonie Hempel, Brian Oliver. LCDB, NIDDK, Bethesda, MD. 542B A screen of GFP-tagged protein traps reveals candidate regulators of post-meiotic spermatogenesis. Nour Aqeel, Yanell Innabi, Shannon Nardozzi, James Fabrizio. Biology Department, College of Mt. St. Vincent, Bronx, NY. 543C Phenotypic and molecular analyses of mulet (mlt) and purity of essence (poe), two genes involved in spermatogenesis in Drosophila melanogaster. Nour Aqeel1, Yanell Innabi1, Shannon Nardozzi1, Astrid Estevez1, Joshian Estevez1, David Guerrero1, Ana Uruena1, Christopher Bazinet2, James Fabrizio1, Janet Rollins1. 1) Biology Department, College of Mt. St. Vincent, Bronx, NY; 2) Department of Biological Sciences, St. John’s University, Janiaca, NY.

544A Functional copies of the Mst77F gene on the Y chromosome of Drosophila melanogaster. Bernardo Carvalho, Flavia Krsticevic, Henrique Santos, Suelen Januaqrio, Carlos Guerra. Dept de Gen, Univ Fed Rio de Janeiro, Rio de Janeiro, Brazil. 545B Genome-wide postmeiotic transcription in Drosophila melanogaster. Domitille S. Chalopin1,2, Maria D. Vibranovski2, Hedibert F. Lopes3, Manyuan Long2, Timothy L. Karr4. 1) Ecole Normale Supérieure de Lyon, Lyon, 69007, FRANCE; 2) Department of Ecology and Evolution, The University of Chicago, Chicago, Illinois, 60637, USA; 3) The University of Chicago Booth School of Business, Chicago, Illinois, 60637, USA; 4) The Biodesign Institute, Arizona State University, Tempe, Arizona, 85287, USA. 546C Structural heterogeneity of the 26S proteasome in Drosophila spermatogenesis: Expression patterns and functional roles of testis specific regulatory particle subunits. Jing Dai, Xiazhen Li, John Belote. Biology, Syracuse University, Syracuse, NY. 547A Spermeye, A novel Drosophila gene implicated in chromatin remodeling. Roshni Ghosh1, Bibi Shalimar Yamin1, Janet Rollins1,2, Christopher Bazinet1. 1) Dept of Biological Sc, St Johns University, Jamaica, NY; 2) Dept of Biological Sc,The College of Mount Saint Vincent,Riverdale Avenue, Riverdale, NY. 548B Identification and characterization of a candidate gene for ms(2)1400, a gene required for unfurling and elongation of mitochondrial derivatives during Drosophila spermatogenesis. Lauren E. Ivey1, Dylan Coughtrey-Davenport1, Cricket G. Wood2, Patricia G. Wilson2, Anthony Mahowald2,4, Margaret T. Fuller2,3, Karen G. Hales1,3. 1) Department of Biology, Davidson College, Davidson, NC; 2) Department of Developmental Biology, Stanford University School of Medicine, Stanford CA; 3) Department of Genetics, Stanford University School of Medicine, Stanford CA; 4) Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago IL. 549C An AAA ATPase required for mitochondrial morphogenesis in developing Drosophila spermatids associates with both mitochondria and centrosomes. Samantha B. Lightcap, Hunter H. Stone, Bevin C. English, Sheena E. Favors, Karen G. Hales. Department of Biology, Davidson College, Davidson, NC. 550A Characterization of peroxiredoxin 3 protein expression in Drosophila melanogaster testes. Thomas M. Onorato1, Melissa Rivera1, Janet Rollins2. 1) Natural Sciences, LaGuardia Community College, Long Island City, NY 11101; 2) Division of Natural Science, College of Mount Saint Vincent, Riverdale, NY 10471. 551B The poly(A) polymerase GLD2 regulates post-meiotic spermatid development in Drosophila. Caroline Sartain, Jun Cui, Mariana Wolfner. Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY.

POSTER SESSIONS

65

Poster board number is in bold above the title. See page 15 for presentation schedule. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

552C Identification of Dtopors domains required for localization in soma and germline tissues. John E. Tomkiel, Fidele Byungura, Maiko Matsui, Krishn Sharma. Dept Biol, Univ North Carolina, Greensboro, NC.

Immunity and pathogenesis

562A ATP sensitive potassium channels modulate antiviral RNAi in the Drosophila heart. Ioannis Eleftherianos1, Stanislava Chtarbanova1, Karen Ocorr2, Rolf Bodmer2, Bruce Beutler3, Jules Hofmann1, Jean-Luc Imler1. 1) Inst Biol Molec et Cellulaire, Strasbourg, France; 2) The Burnham Institute, La Jolla, CA; 3) TSRI, La Jolla, CA.

553A Regulation of immune system development and homeostasis by the Drosophila beta-arrestin Kurtz. Saima Ghafoor Anjum, Alexey Veraksa. Dept. of Biology, University of Massachusettes, Boston MA 02125.

563B Identification of host factors and pathways essential for West Nile virus replication. Sheri L. Hanna1, Robert W. Doms1, Sara Cherry1,2. 1) Dept Microbiology, Univ Pennsylvania, Philadelphia, PA; 2) Penn Genome Frontiers Inst, Univ Pennsylvania, Philadelphia, PA.

554B Identifying and characterizing a novel immune-specific phagocytosis mutant. Elizabeth A. Gonzalez, Becky K. Brisson, Louisa P. Wu. CBMG, UMCP, College Park, MD. 555C Genetic controls of age related phagocytic ability in Drosophila. Lucas A. Horn, Jeff Leips, Michelle Starz-Gaiano. University of Maryland Baltimore County, Baltimore, MD. 556A Pathways in Drosophila hemocyte activation and differentiation. Jesper Kronhamn1, Ines Anderl1,3, Jens-Ola Ekström1, Michael Williams2, AnnaKarin Kronhamn1, Dan Hultmark1,3. 1) Umeå University, Umeå, Sweden; 2) University of Aberdeen, Aberdeen, UK; 3) University of Tampere, Tampere, Finland. 557B Drosophila Rel proteins are central regulators of a robust, multi-organ immune network. Nina M. Matova. Inst Mol Med, Lisbon, Portugal. 558C Molecular and functional characterisation of the hematopoietic niche in Drosophila melanogaster. Delphine Pennetier, Justine Oyallon, Ismael Morin-Poulard, Alain Vincent, Michèle Crozatier. CNRS, centre de biologie du développement, toulouse, toulouse, France. 559A Exploring the roles of hemocytes in the antiviral response of Drosophila. Javier Robalino, Louisa Wu. Center for Biosystems Research, University of Maryland, College Park, MD. 560B Zfrp8, JAK/STAT and Hematopoiesis. William Tan, Svetlana Minakhina, Ruth Steward. Waksman Institute Rutgers University 190 Frelinghuysen Rd Piscataway, NJ 08854. 561C RNAi screening reveals new players in the defense against RNA viruses. Jie Xu1, Leah Sabin1, Rui Zhou2, Gregory Hannon3, Sara Cherry1. 1) School of Medicine, University of Pennsylvania, Philadelphia, PA; 2) Department of Genetics, Harvard Medical School, Howard Hughes Medical Institute, Boston, MA; 3) Watson School of Biological Sciences, Howard Hughes Medical Institute, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.

564C The role of Drosophila Toll-like receptors in viral infection and autophagy. Maggie Nakamoto, Shelly Bambina, Spencer Shelly, Sara Cherry. Department of Microbiology, University of Pennsylvania School of Medicine, Philadelphia, PA. 565A Drosophila as a model of cholera: Identification of Vibrio cholerae genes important for virulence in Drosophila melanogaster. Alexandra E. Purdy, Sarah Chang, Cindy Capitolin, Paula Watnick. Division of Infectious Diseases, Children’s Hospital Boston, Boston, MA. 566B Identification and Characterization of Mutants that Affect Antiviral Immunity in Drosophila melanogaster. Jessica Tang, Anne Macgregor, Louisa Wu. University of Maryland Biotechnology Institute, College Park, MD. 567C Host and pathogen glycosaminoglycan-binding proteins modulate antimicrobial peptide responses. Zhipeng Wang, Lindsay Flax, Miriam Baron. Channing laboratory, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA. 568A IMD cleavage and K63-polyubiquitination in NF-KB innate immune signaling. Li Chen, Neal Silverman, Nicholas Paquette. Med/Div Infectious Dis, Univ Massachusetts Med Sch, Worcester, MA. 569B Genome wide association tests for age-specific immunocompetence in Drosophila. Christopher H. Ferguson, Arunkumar Junuthula*, Sameen Raza*, Michael Topper*, Won Woo*, Nebyat Yonas*, Jeff Leips, * authors that contributed to this work. Dept. of Biological Sciences, University of Maryland Baltimore County, Baltimore, MD. 570C The Endocytic Pathway is Required for Drosophila Toll Innate Immune Signaling. Hon-Ren Huang1, Zhijian ‘James’ Chen2, Sam Kunes1, Geen-Dong Chang3, Tom Maniatis1. 1) Harvard University, Cambridge, MA; 2) UT Southwestern Medical Center, Dallas, TX; 3) National Taiwan University, Taipei, Taiwan. 571A Output of JAK/STAT signaling is modulated by ken and CtBP in Drosophila melanogaster hematopiesis. Soichi Tanda1,2, William Johnson1, Aditi Vyas2. 1) Dept Biological Sci; 2) Molecular and Cellular Biology Program, Ohio Univ, Athens, OH.

66

POSTER SESSIONS Poster board number is in bold above the title. See page 15 for presentation schedule. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

572B The Role of Pdm1/nub in Drosophila immunity. Widad Dantoft, Hanna Uvell, Anna Junell, Ylva Engström. Dept. of Molecular Biology and Functional Genomics, Stockholm University, Sweden. 573C The Drosophila homologue of human multidrug resistanceassociated protein 4 (dMRP4) is a negative regulator of the Imd pathway in hypoxia. He Huang, Ying Lu-Bo, Gabriel Haddad. Univ California, San Diego, La Jolla, CA. 574A Wolbachia encoded factors determine differential targeting of stem cell niche. Horacio M. Frydman1,2, Kanchana Panaram1, Michelle Toomey1, Fast Eva1, Cathy Beaty1, Barrett Steinberg1. 1) Dept Biol, Boston Univ, Boston, MA; 2) National Emerging Infectious Diseases Laboratories,Boston, MA. 575B Endosymbiont Wolbachia pipientis selectively inhibits West Nile virus infection of Drosophila melanogaster. Robert L. Glaser1,2. 1) Wadsworth Ctr, New York State Dept Hlth, Albany, NY; 2) Dept Biomedical Sciences, University at Albany, Albany, NY. 576C Wolbachia encoded factors determine differential targeting of stem cell niches. Kanchana Panaram1, Michelle Toomey1,2, Fast Eva1, Cathy Beatty1, Barrett Steinberg1, Horacio Frydman1,2. 1) Dept Biology, Boston University, Boston, MA; 2) National Emerging Infectious Diseases Laboratories, Boston, MA.

Neural physiology and behavior 577A Age-Related Deterioration of Recovery Sleep. Marishka K. Brown, Nirinjini Naidoo. Center for Sleep & Respiratory Neurobiology, Univ of Pennsylvania, Philadelphia, PA. 578B Molecular Timing of Iron Homeostasis in Drosophila melanogaster. Konstantinos Mandilaras, Fanis Missirlis. SBCS, Queen Mary University of London, United Kingdom. 579C Glial Cells Regulate Circadian Behavior and Neuronal Clock Protein Abundance. Shui-Ying Ng1, Ozge Tasdemir2, F. Rob Jackson1. 1) Department of Neuroscience and Center for Neuroscience Research, Tufts University School of Medicine, Boston, MA; 2) Department of Neurobiology, University of Massachusetts Medical School, Worcester, MA. 580A jim lovell, A Gene with Structural and Functional Similarities to fruitless. Kathleen M. Beckingham, Sonia Bjorum. Dept Biochem & Cell Biol, Rice Univ, Houston, TX. 581B The serotonin 5-HT7Dro receptor is essential for normal courtship and mating in Drosophila. Jaime T. Becnel, Oralee Johnson, Charles Nichols. Dept Pharmacology, LSU Health Sciences Ctr, New Orleans, LA.

582C Ecdysone receptor acts in fruitless-expressing neurons to mediate Drosophila courtship behaviors. Justin Dalton1, Matthew Lebo1, Laura Sanders1, Fengzhu Sun1, Michelle Arbeitman1,2. 1) Molecular and Computational Biology, University of Southern California, Los Angeles, CA; 2) Neurobiology, University of Southern California, Los Angeles, CA. 583A Neural masculinization in the Drosophila brain is controlled by the recruitment of chromatin regulators Rpd3 or HP1 to a Fruitless-containing protein complex. Hiroki Ito1,2,3, Masayuki Koganezawa1, Manabu Ote1,2, Ken Matsumoto2, Chihiro Hama3, Daisuke Yamamoto1,2. 1) Graduate School of Life Sciences, Tohoku University, Sendai, Japan; 2) Advanced Institute for Science and Engineering, Waseda University, Nishi-Tokyo, Japan; 3) Center for Developmental Biology, RIKEN, Kobe, Japan. 584B A large scale screening of GAL4 lines to search for command neurons in the Drosophila brain. Moto Yoshihara1, Thomas Flood1, Michael Gorczyca1, Benjamin White2, Kei Ito3. 1) Dept of Neurobiol, UMass Med Sch, Worcester, MA; 2) Lab of Mol Biol, NIMH, Bethesda, MD; 3) Inst of Mol and Cell Biosci, Univ of Tokyo, Tokyo, Japan. 585C The Role of Metal Ion Homeostasis in Feeding Behavior. Angie D. LaMora1, Jennifer Duncan2, Yehuda Ben-Shahar1. 1) Biology, Washington University, St Louis, MO; 2) Pediatrics, Washington University, St Louis, MO. 586A A possible role for the doublesex-related factor DMRT93B in digestive tract function. Diana O’Day, William Mattox. The University of Texas MD Anderson Cancer Center, Department of Genetics, Houston, TX. 587B Interactions Between Juvenile Hormone and Dopamine. Kathryn J. Argue, Amber Yun, Wendi Neckameyer. Saint Louis University, St. Louis, MO. 588C Eclosion Gates Neuronal Competence to Release the Hormone Bursicon. Nathan Peabody, Benjamin White. Lab Molecular Biology, NIMH/NIH, Bethesda, MD. 589A The Role of Nicotinic Acetylcholine Receptors in Development and Insecticide Resistance. Jude Mitchell, Phil Daborn, Phil Batterham, Trent Perry. Genetics, University of Melbourne, Melbourne, Victoria, Australia. 590B Insecticide resistance - a tool for dissecting nicotinic acetylcholine receptor biology. Trent Perry, Jason Somers, Philip Batterham. Bio21 Institute - Genetics, The University of Melbourne, Parkville, Victoria, Australia. 591C Reduction of narrow abdomen function blunts photic behaviors in Drosophila larvae. David J. Sandstrom1, Kelley L. Hagerich2, Howard A. Nash1. 1) Laboratory of Molecular Biology, NIMH, NIH Bethesda, MD; 2) University of Pittsburgh, Pittsburgh, PA.

POSTER SESSIONS

67

Poster board number is in bold above the title. See page 15 for presentation schedule. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

592A Complex electroretinogram phenotypes reveal the influence of the narrow abdomen ion channel on neuronal circuits. Robert L. Scott, Howard A. Nash. Laboratory of Molecular Biology, NIMH, NIH, Bethesda, MD. 593B The Drosophila TRPA1 Channel Is Required for Thermal and Mechanical Nociception. Lixian Zhong1, Daniel W. Tracey2,3,4. 1) Dept of Pharmacology; 2) Dept of Cell Biology; 3) Dept of Neurobiology; 4) Dept of Anesthesiology, Duke Univ, Durham, NC. 594C Non-genomic actions of the steroid hormone ecdysone in adult Drosophila. Hiroshi Ishimoto1, Zhe Wang2, Chun-Fang Wu2, Toshi Kitamoto1. 1) Anesthesia, Univ Iowa, Iowa City, IA; 2) Biology, Univ Iowa, Iowa City, IA. 595A Drosophila CPEB protein Orb2 and long-term memory formation. Alfonso Martin-Peña, Ronald Davis. Neuroscience, The Scripps Research Institute, Jupiter, FL. 596B Pharmacological rescue of NF1-associated learning defects. Linnea R. Vose, Peter O’Brien, Frances Hannan. Cell Biology and Anatomy, New York Medical College, Valhalla, NY. 597C Drosophila short neuropeptide F and receptor modulate cAMPPKA-CREB pathway through GAs in Drosophila BG2-c6 cells. Seung-Hyun Hong, Kyu-Sun Lee, Ae-Kyeong Kim, Kweon Yu. Aging Research Center, KRIBB, Daejeon, Korea. 598A BMP signaling in a Drosophila neuronal subset co-regulates multiple neuropeptides that are required for execution of an innate behavior. Lyubov Veverytsa, Douglas W. Allan. Department of Cellular and Physiological Sceinces, University of British Columbia, Vancouver, British Columbia, Canada. 599B Analysis of Catecholamines up,mechanisms of action in the regulation of dopamine Synthesis and Transport in Drosophila. Olugbenga M. Doherty, Janis O’Donnell. Department of Biological Sciences,University of Alabama,Tuscaloosa, AL 35487. 600C Histamine and eGFP distribution in transgenic flies bearing an Hdc promoter-eGFP gene fusion. Embriette Hyde, Wendi-Jo Ervin, Martin G. Burg. Biomedical Sciences, Grand Valley State University, Allendale, MI 49426, MI. 601A The Genetic Basis of Startle-Induced Locomotion in Drosophila melanogaster. Yazmin L. Serrano1,2, Akihiko H. Yamamoto1,2, Robert R. H. Anholt1,2,3, Trudy F. C. Mackay2,3. 1) Biology, NCSU, Raleigh, NC; 2) WM Keck Center for Behavioral Biology, NCSU, Raleigh, NC; 3) Genetics, NCSU, Raleigh, NC. 602B Proteolysis regulators in the seminal fluid of Drosophila melanogaster males. Jessica Lynn Sitnik, Mariana Wolfner. Dept. of Molecular Biology and Genetics, Cornell University, Ithaca, NY.

603C RNAi-mediated dissection of olfactory behavioral response profiles of odorant binding proteins in Drosophila melanogaster. Shilpa Swarup1,2, Trudy Mackay1,2, Robert Anholt1,2,3. 1) Department of Genetics; 2) W. M. Keck Center for Behavioral Biology; 3) Department of Biology, North Carolina State University, Raleigh, NC 27695. 604A Spontaneous decision making in maze running behavior in flies undergoing long-term selection for extreme geotactic response. Daniel P. Toma1, Richard W. Cross2, Justin Perlich1, Chad Taylor1, Elijah Wreh1. 1) Dept Biological Sci, Minnesota State Univ, Mankato, MN; 2) AccountabilityWorks, 7315 Wisconsin Avenue, Bethesda, MD. 605B Deletion mapping of a candidate gene with a spontaneous mutation that causes flightlessness in Drosophila melanogaster. Tara L. Travaline, Justine Miller, Phillip T. Barnes. Biology Department, Connecticut College, New London, CT. 606C The Drosophila larval hypoxia escape response is mediated through atypical soluble guanylyl cyclases and cGMP gated ion channels. Anke Vermehren, David Morton. Integrative Biosci, OHSU, Portland, OR. 607A Epistatic Interactions Attenuate Mutations that Affect Startle Behavior in Wild-Derived Lines of Drosophila melanogaster . Akihiko Yamamoto1,2, Robert Anholt1,2,3, Trudy Mackay2,3. 1) Dept Biology, North Carolina State Univ, Raleigh, NC; 2) W. M. Keck Center for Behavioral Biology, North Carolina State University, Raleigh, NC; 3) Dept Genetics, North Carolina State Univ, Raleigh, NC. 608B Daytime sleep shows greater variance than nighttime sleep in Drosophila melanogaster. John E. Zimmerman, May T. Chan, Allan I. Pack. Center for Sleep and Respiratory Neurobiology, University of Pennsylvania School of Medicine, Philadelphia, PA. 609C Alternate NOMPC channel pore isoforms in mechanosensory organs. Shao-Kuei Huang1, Maurice Kernan2. 1) Program in Neuroscience, Stony Brook University, Stony Brook, NY; 2) Center for Developmental Genetics, Stony Brook University, NY. 610A Regulation of social behaviors by Deg/ENaC signaling in Drosophila. Beika Lu, Yehuda Ben-Shahar. Biology, Washington University in St. Louis, St. Louis, MO. 611B Translation of Olfactory Input into Behavioral Output in the Drosophila Larva. Shelby A. Montague1,2, Dennis Mathew2, John R. Carlson2. 1) Department of Cellular and Molecular Physiology, Yale University, New Haven, CT; 2) Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT.

68

POSTER SESSIONS Poster board number is in bold above the title. See page 15 for presentation schedule. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

Neurogenetics and neural development 612C The unfulfilled/DHR51 gene is required for the development of mushroom body neuropil KE Bates, C Sung, S Robinow; Dept of Zoology, University of Hawaii, Honolulu, HI. Karen E. Bates, Carl S. Sung, Steven Robinow. Department of Zoology, University of Hawaii, Honolulu, HI. 613A The Sponge/Elmo complex functions in CNS development in concert with N-cadherin. Erika R. Geisbrecht, Bridget Biersmith, Kenny Bauman, Cindy (Ze) Liu. Cell Biology and Biophysics, University of Missouri-Kansas City, Kansas City, MO. 614B Down Syndrome Cell Adhesion Molecule (DSCAM) and Neuronal Connection Respecification. Hitesh Kathuria. School of Natural Science and Mathematics, Indiana University East, Richmond, IN. 615C Characterizing the Molecular Mechanisms of Axon Guidance: Activation and Regulation of the Axon Guidance Receptor Plexin. Taehong Yang, Jonathan Terman. Departments of Neuroscience and Pharmacology, and Neuroscience Graduate Program, The University of Texas Southwestern Medical Center, Dallas, TX 75390. 616A Datou functions downstream of Lethal Giant Larvae and is required for mislocalization of cell fate determinants in lgl mutants. Lihui Goh1,2, Shuping Lin1, Xiaohang Yang1,2. 1) Institute of Molecular and Cell Biology, Singapore; 2) National University of Singapore, Singapore. 617B Identification of Sub-Pattern-Specific cis-Regulatory Modules for a CNS Neuroblast Temporal Network Gene. Mukta R. Kundu, Thomas Brody, Jermaine Ross, Alexander Kuzin, Ward F. Odenwald. Neural Cell Fate Determinants, NINDS, Bethesda, MD. 618C Role of Poxn in Drosophila brain development: fate determination of ellipsoid body large-field neurons and ventral projection neurons. Shilpi Minocha, Werner Boll, Markus Noll. Institute of Molecular Biology,University of Zürich,Switzerland. 619A Investigating the role of Startled during asymmetric cell division of neural progenitors. Ying Ying Sung1,2, Newman Tze3, Xiaohang Yang1,2. 1) Agency for Science, Technology and Research (A*STAR), Singapore; 2) National University of Singapore (NUS), Singapore; 3) Nanyang Technological University, Singapore. 620B Cell lineage analysis of the Drosophila central complex, the insect brain center for locomotor control. Shun-Jen J. Yang, Hung-Hsiang Yu, Julie Simpson, Tzumin Lee. Janelia Farm Research Campus, HHMI, Ashburn, VA 20147.

621C Assembly of the Olfactory Neural Circuit in the Drosophila Antennal Lobe. Hung-Hsiang Sam Yu1, Jacob Yang1, ChihFei Kao2, Tzumin Lee1,2. 1) Janelia Farm Research Campus, Howard Hughes Medical School, Ashburn, VA; 2) Department of Neurobiology, University of Massachusetts, Wocester, MA. 622A The COPII Coat Protein Sec31 Regulates da Neuron Dendrite Morphogenesis. Srividya Chandramouli Iyer, Aravinda Kuntimaddi, Daniel N. Cox. Molec & Microbiol, Krasnow Inst Adv Study, George Mason University, Fairfax, VA. 623B dilatory, a direct target of Atonal, is required for the structure ad function of mechanosensory cilia in Drosophila. Lina Ma1, Sebastian Cachero2, Andrew Jarman1. 1) Ctr Integrative Physiology, Univ Edinburgh, Edinburgh, United Kingdom; 2) MRC Laboratory of Molecular Biology,Cambridge, United Kingdom. 624C The role of post-transcriptional gene regulation in dendritic morphogenesis of the Drosophila larval peripheral nervous system. Eugenia C. Olesnicky, Elizabeth R. Gavis. Molecular Biology, Princeton University, Princeton, NJ. 625A The Drosophila RhoGEF, Trio, Mediates Class-Specific Dendrite Morphogenesis via Differential Regulation of the Actin Cytoskeleton. Riaz Shinwari, Dennis Wang, Eswar PR Iyer, Srividya C. Iyer, Daniel N. Cox. Molec. & Microbiol, Krasnow Inst Adv Study, George Mason University, Fairfax, VA. 626B Nmnat is required for maintaining dendritic field coverage of Drosophila sensory neurons. Yuhui Wen, R. Grace Zhai, Michael Kim. Department of Molecular and Cellular Pharmacology, University of Miami, Miller School of Medicine, Miami, FL. 627C Netrins guide glial cell migration in the Drosophila embryo. Benjamin Altenhein, Christian von Hilchen, Gerhard Technau. Institute of Genetics, University of Mainz, Germany. 628A Glial remodeling during abdominal segmental nerve fusion in the pupa. Soumya Banerjee, Matt Seifert, Bridget Hartman, Meredith Dorr, Joyce Fernandes. Dept Zoology, Miami Univ, Oxford, OH. 629B Degeneration of optic lamina caused by defective endocytic function in glial cells. Yuan M. Lee1,2, Y. Henry Sun1,2. 1) N415, Inst Molecular Biology, Taipei, Taiwan; 2) Institute of Genomic Science, National Yang Ming University, Taipei, Taiwan. 630C Identifying novel modes of transcriptional regulation in CNS midline glia. Joseph Pearson, Joseph Watson, Scott Wheeler, Stephen Crews. Biochemistry and Biophysics, UNC Chapel Hill, Chapel Hill, NC.

POSTER SESSIONS

69

Poster board number is in bold above the title. See page 15 for presentation schedule. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

631A meanie jim, a new CNS-specific gene related to dachshund that regulates ecdysone receptor expression in the larval mushroom body. Stuart Newfeld, Michael Stinchfield, Norma Takaesu. Sch Life Sci, Arizona State Univ, Tempe, AZ. 632B Expression of the Methuselah-like GPCRs in Drosophila. Dana A. Hallal, Meghna V. Patel, Denise N. Bronner, Rami K. Zeina, Mark F. A. VanBerkum. Biological Sciences, Wayne State University, Detroit, MI. 633C The function of dRFX in central brain neurons. Anne Laurencon, Guillaume Grenier, Joëlle Thomas, Elisabeth Cortier, Bénédicte Durand. CGMC UMR 5534, Univ Lyon-1, Villeurbanne, France. 634A Nanos regulation and function in Drosophila dendritic arborization neurons. Xin Xu1, Jillian Brechbiel2, Elizabeth Gavis1. 1) Molec Biol, Princeton Univ, NJ; 2) The Joseph Stokes Jr. Research Institute, PA. 635B Cis-Regulatory Integration of Intrinsic Transcription Factors with Target-Derived Signals in Neuronal Differentiation. Anthony J. E. Berndt1, Marc Ridyard1, Jonathan C. Y. Tang2, Douglas Allan1. 1) Dept of Cellular & Physiological Science Life Sciences Centre 2350 Health Sciences Mall University of British Columbia Vancouver BC Canada V6T 1Z3; 2) Department of Molecular and Cellular Biology Harvard University 16 Divinity Ave. Cambridge, MA 02138. 636C Genetic interactions between CK2, E(spl), Notch and PP2A during Drosophila neurogenesis. Anasua Bose, Bhaskar Kahali, Clifton Bishop, Ashok Bidwai. Biology, West Virginia Univ, Morgantown, WV. 637A Characterization of rhomboid enhancer activity in a subset of embryonic head cells required for growth and viability. Amy L. Gresser, David Li-Kroeger, Lorraine Witt, Brian Gebelein. Division of Developmental Biology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH. 638B The brain insulin-producing cell neuroblast identity is the default fate of a neurogenic placode equivalence group. Helen Hwang, Eric Rulifson. Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Diabetes Center, Univ of California San Francisco. 639C Chinmo specifies discrete blocks of neuronal temporal cell fates in a rapidly changing neuronal lineage. Chih-Fei Kao1, HungHsiang Yu2, Tzumin Lee1,2. 1) Department of Neurobiology, UMass Medical School, Worcester, MA 01605, USA; 2) Janelia Farm Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.

640A O-glucosylation of multiple EGF-like repeats of Notch by Rumi is required for optimal Notch signaling. Jessica Leonardi1,4, Rodrigo Fernandez-Valdivia4, Nadia A. Rana2, Hideyuki Takeuchi2, Yi-Dong Li4, Amanda Simcox3, Robert S. Haltiwanger2, Hamed Jafar-Nejad1,4. 1) Program in Developmental Biology, Baylor College of Medicine, Houston, TX; 2) Stony Brook University, Stony Brook, NY; 3) Ohio State University, Columbus, OH; 4) IMM, UT Health Science Center, Houston, TX. 641B The Role of the Forkhead Gene fd3F in Drosophila Chordotonal Neuron Differentiation. Fay Newton, Andew Jarman. Centre for Integrative Physiology, School of Biomedical Sciences, University of Edinburgh, Edinburgh, United Kingdom. 642C Dorsal eye selector pannier (pnr) suppresses retinal differentiation in the Drosophila eye. Sarah M. Oros1,2, Meghana Tare2, Amit Singh1,2,3. 1) Premedical Programs, University of Dayton, Dayton, OH 45469; 2) Department of Biology, University of Dayton, Dayton, OH 45469; 3) Center for Tissue Regeneration and Engineering at Dayton (TREND), University of Dayton, Dayton, OH 45469. 643A Ttk69-dependent repression of lozenge prevents the ectopic development of R7 cells. John A. Pollock1, Nicole Siddall2, Gary Hime2, Phil Batterham2. 1) Duquesne Univ, Pittsburgh, PA 15282; 2) Univ of Melbourne, Parkville, 3010,Victoria, Australia. 644B Genetic control of rhodopsin switch during metamorphosis. Maria Tsachaki, Simon Sprecher. University of Fribourg, Fribourg, Switzerland. 645C Genetic interactions of p38a, CK2 and Notch during Drosophila eye development. Chong Yin, Bhaskar Kahali, Anasua Bose, Sophia Zhang, Clifton Bishop, Ashok Bidwai. Biology, West Virginia University, Morgantown, WV 26506. 646A A Trophic Role for Serotonin in the Development of a Simple Feeding Circuit. Wendi S. Neckameyer, Parag Bhatt. Dept Pharmac & Physiol Sci, St Louis Univ School Med, St Louis, MO. 647B An enhancer based approach to the neuronal cell types of the optic lobe. Aljoscha Nern1, Barret Pfeiffer1, Teri Ngo1, Arnim Jennet1, Heather Dionne1, Chris Murphy1, Larry Zipursky2, Gerald Rubin1. 1) HHMI/Janelia Farm Research Campus, Ashburn, VA; 2) HHMI/UCLA, Los Angeles, CA. 648C A Screen for Ion Channels Functionally Required for Larval Nociception. Kia C. E. Walcott1, W. Daniel Tracey Jr.2,3,4. 1) Dept. of Pharmacology, Duke University, Durham, NC; 2) Dept. of Anesthesiology, Duke University, Durham, NC; 3) Dept. of Cell Biology, Duke University, Durham, NC; 4) Dept. of Neurobiology, Duke University, Durham, NC.

70

POSTER SESSIONS Poster board number is in bold above the title. See page 15 for presentation schedule. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

649A The proprioceptive and contractile systems in Drosophila are both patterned by the EGR family transcription factor Stripe. Adi Salzberg, Yifat Klein, Naomi Halachmi, Matia Nirit, Moran Toder. Gen/Rappaport Fac Medicine, Technion Israel Ins Technology, Haifa, Israel. 650B TU-tagging identifies trithorax-group regulators of neural progenitor proliferation. Mike Cleary, Sarah Min, Miguel Manansala, Frank Weckerle, Maxine Umeh. University of California, Merced, Merced, CA. 651C Characterization of a Dominant Negative EMS-Induced Mutation That Affects the Asymmetric Organization of Dividing Drosophila Neuroblasts. Zhenxing Huang1,3, Greg Somers2, Xiaohang Yang1,3. 1) Insitute of Molecular & Cellular Biology, 61 Biopolis, Drive, Singapore; 2) Temasek Life Sciences Laboratory, 1 Reserch Link, Singapore; 3) Department of Anatomy, National University of Singapore, Singapore. 652A Inactivation of both foxo and reaper promotes long-term adult neurogenesis in Drosophila. Sarah E. Siegrist1, Najm S. Haque1, Chun-Hong Chen2, Bruce A. Hay3, Iswar K. Hariharan1. 1) Dept. of Molecular and Cell Biology, Univ of California, Berkeley, CA; 2) Division of Molecular and Genomic Medicine, National Health Research Institutes, Taiwan; 3) Biochemistry & Molecular Biophysics, California Institute of Technology, Pasadena, CA. 653B The endocytic protein A-Adaptin inhibits self-renewal of Drosophila neural stem cells. Yan Song1,2, Bingwei Lu1,2. 1) Dept Pathology, Stanford Univ, Stanford, CA; 2) GRECC/ VAPAHCS, Palo Alto, CA. 654C Three Drosophila Liprins interact to control synapse formation. Sergio Astigarraga, Hofmeyer Kerstin, Reza Farajian, Jessica Treisman. Developmental Genetics, Skirball Institute, NYU School of Medicine, New York, NY. 655A Drosophila Neuroligin Is Critically Required for Synapse Formation and Post-synaptic Differentiation at the NMJ. Mingkuan Sun1, Guanglin Xing1, Guangming Gan1, Sheila Irene With2, Fading Chen1, Xiankun Zeng1, Ming Fang1, Liudi Yuan1, Gabrielle L. Boulianne2, Wei Xie1. 1) Southeast University Medical School, 87 Dingjiaqiao Road, Nanjing 210009, China; 2) The Hospital for Sick Children, Toronto, ON, Canada, M5G 1L7.

Pattern formation 656B Nubbin promotes wing blade development by repressing unpaired expression and restricting JAK/STAT signaling to the wing hinge. Erika A. Bach, Aidee Ayala-Camargo, Michelle Krasny, Maria Sol Flaherty. Dept Pharm, MSB-497B, New York Univ Sch Med, New York, NY.

657C Dorsal fate induction along the anterior-posterior axis of the follicular epithelium. Jean-François Boisclair Lachance, Nigel Burke, Laura Nilson. McGill University, Dept. of Biology, Montreal, QC, Canada. 658A The fat facets deubiquitinase modulates Dpp responsiveness in dorsal-ventral pattern formation. Stuart Newfeld, Michael Stinchfield, Ashley Castillo, Norma Takaesu. Sch Life Sci, Arizona State Univ, Tempe, AZ. 659B defective proventriculus (dve), a new member of DV patterning in the eye. Oorvashi Roy G. Puli1, Takeshi Yorimitsu3, Hideki Nakagoshi3, Amit Singh1,2,4. 1) Department of Biology, University of Dayton, Dayton, OH; 2) Premedical Program, University of Dayton, 300 College Park Drive, Dayton OH; 3) Graduate School of Natural Science and Technology, Okayama University, 3-1-1 Tsushima-naka, Kita-ku, Okayama 700-8530, Japan; 4) Center for Tissue Regeneration and Engineering at Dayton (TREND), University of Dayton. 660C Quantitative imaging of the Dorsal nuclear gradient reveals limitations to threshold-dependent patterning in Drosophila. Gregory T. Reeves, Louisa M. Liberman, Angelike Stathopoulos. Div Biol, Caltech, Pasadena, CA. 661A Multiscale modeling of diffusion in the early Drosophila embryo. Christine Sample, Stanislav Shvartsman. Department of Chemical Engineering and Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ. 662B Syntaxin-1A regulates Gurken trafficking for efficient dorsalventral axis patterning. Ai-Guo Tian, Yoichiro Tamori, Yi-Chun Huang, Natalia Toledo Melendez, Wu-Min Deng. Dept of Biol Sci, Florida State Univ, Tallahassee, FL. 663C Functional analysis of Drosophila ADI1 in border cell migration. He-Yen Chou, Ying-Hao Wen, Yen-Hsien Lee, Shu-Heng Zeng, Guan-Lin Shiu, Li-Mei Pai. Chang Gung University, Tao-Yuan, Taiwan, R.O.C. 664A Organisation and function of the microtubule network during tracheal morphogenesis. Pierre-Marie Le Droguen, Antoine Guichet, Véronique Brodu. Group Polarity and Morphogenesis Institut Jacques MONOD University Paris 7, Paris, France. 665B The Role of Extramacrochaetae; a HLH Protein Involved in D/V and A/P Patterning Within the Retina. Carrie M. Spratford, Justin Kumar. Dept. of Biology, Indiana University, Bloomington, IN, 47405.

POSTER SESSIONS

71

Poster board number is in bold above the title. See page 15 for presentation schedule. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

666C Negative feedback bends the gene expression boundary in a developing tissue. Jeremiah J. Zartman1, Lily S. Cheung1, Christine Bonini1, Benjamin Haley2, Stanislav Y. Shvartsman1. 1) Lewis Sigler Institute and Department of Chemical Engineering, Carl Icahn Laboratory, Washington Road, Princeton University, Princeton, NJ 08544, USA; 2) Department of Molecular Cell Biology, Division of Genetics, Genomics, and Development, Center for Integrative Genomics, University of California, Berkeley, California 94720-3200, USA. 667A Sine oculis positively and negatively regulates eyeless expression during eye development. Mardelle R. Atkins1, Yuwei Jiang2, Graeme Mardon1,2,3,4,5. 1) Interinstitutional Program in Developmental Biology, Baylor College of Medicine, Houston, TX; 2) Dept. of Genetics, Baylor College of Medicine, Houston, TX; 3) Dept. of Neuroscience, Baylor College of Medicine, Houston, TX; 4) Dept. of Pathology, Baylor College of Medicine, Houston, TX; 5) Dept. of Opthalmology, Baylor College of Medicine, Houston, TX. 668B Role of Spastin in rhabdomere elongation and morphogenesis of Drosophila photoreceptor. Sang-Chul Nam. Department of Biology, Baylor University, Waco, TX. 669C Role of an E3 ubiquitin ligase in ventral eye development. Meghana Tare1, Madhuri Kango-Singh1,2,3, Amit Singh1,2,3. 1) Department of Biology, University of Dayton, 300 College Park Drive, Dayton OH; 2) Premedical Program, University of Dayton, 300 College Park Drive, Dayton OH; 3) Center for Tissue Regeneration and Engineering at Dayton (TREND), University of Dayton. 670A upd3 regulates Drosophila eye development. Yu-Chen Tsai1, Yu-Ting Huang1, Yu-Ting Chiu2, Shih-Han Lin1. 1) Dept Life Science, Tung-hai Univ, Taichung, Taiwan; 2) Institute of Mol biol, Academia Sinca, Taipei, Taiwan. 671B Ey-Cut Antagonism Controls Eye-Antenna Division. ChengWei Wang1,2, Y. Henry Sun1,2. 1) Institute of Molecular Biology, Academia Sinica, Nankang, Taipei, Taiwan, Republic of China; 2) Institute of Genetics, National Yang-Ming University, Shipai, Taipei, Taiwan, Republic of China. 672C Notch Mediated Growth in the Eye Requires the So-Eya Complex. Bonnie Weasner, Justin Kumar. Dept. of Biology, Indiana University, Bloomington, IN. 673A Regulation of the Sex combs reduced gene within the transverse row bristle primordia of legs in the first thoracic segment. Emily R. Wyskiel, Stuti Shroff, Teresa V. Orenic. Laboratory for Molecular Biology, Dept of Biological Sciences, University of IL at Chicago, Chicago, IL. 674B Regulation of leg size and shape by the Dachsous/Fat signalling pathway during cricket leg regeneration. Sumihare Noji, Tetsuya Bando, Taro Mito, Taro Nakamura, Takahito Watanabe, Hideyo Ohuchi. University of Tokushima Graduate School, Tokushima city, 770-8506, Japan.

675C The hth isoform carrying a 3bp micro-exon exhibits distinct developmental functions. Ling Wen Chang, Y. Henry Sun. Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan. 676A A Model for Cell Counting: Establishing Cell Proliferation, Death, and Gene Expression Dynamics of Terminal Filament Formation in D. melanogaster. Delbert A. Green1, Cassandra Extavour2. 1) Molecular and Cellular Biology, Harvard University, Cambridge, MA; 2) Organismic and Evolutionary Biology, Harvard University, Cambridge, MA. 677B Identification and Characterization of the wings apart gene in Drosophila. Ginny Morriss, Carmelita Jaramillo, Richard Cripps. Biol, Univ New Mexico, Albuquerque, NM. 678C The role of Fat protein interactors in Planar Cell Polarity and tissue growth. Robyn Rosenfeld1,2, Anson Sing1,2, Helen McNeill1,2. 1) Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada; 2) Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, ON, Canada. 679A Blistered Germ-Line Clones Reveal a Requirement in Early Embryonic Development. Francisco Javier Carmona Aldana, Juan Rafael Riesgo Escovar. Departamento de Neurobiología del Desarrollo y Neurofisiología, Instituto de Neurobiología, Universidad Nacional Autónoma de México, campus Juriquilla, Juriquilla, Querétaro, Mexico. 680B The generation and control of spatial noise during segmentation gene expression: transcriptional regulation of hunchback. David M. Holloway1, Francisco JP Lopes2, Luciano da F. Costa3, Bruno AnN Travencolo;olo3, Alexander V. Spirov4. 1) Mathematics, British Col Inst Tech, Burnaby; Biology, U Victoria, BC, Canada; 2) Inst. de Biofisica, Univ Fed do Rio de Janeiro, Brazil; 3) Inst de Fisica de Sao Carlos, Univ Sao Paulo, Brazil; 4) Comp Sci and CEWIT, Stony Brook Univ, NY, USA. 681C Artificial selection on egg size perturbs early pattern formation in Drosophila melanogaster cycle 14 embryos. Cecelia M. Miles1, Susan Lott2, Cris Luengo Hendriks3, Marty Kreitman1. 1) Dept Ecology & Evolution, Univ Chicago, Chicago, IL; 2) Dept Molec & Cell Biol, Univ California Berkeley, Berkeley, CA; 3) Centre for Image Analysis, Swedish University of Agricultural Sciences, Uppsala, Sweden. 682A The Bicoid gradient in Drosophila is still puzzling: new data requires new concepts. Alexander V. Spirov1, Theodore Alexandrov2, David M. Holloway3, Nina E. Golyandina4. 1) Computer Science, State Univ New York, Stony Brook, NY; 2) Center for Industrial Mathematics, Univ Bremen, Bremen, Germany; 3) Mathematics, British Columbia Institute of Technology, Burnaby; Biology, Univ Victoria, BC, Canada; 4) Mathematics and Mechanics, St-Petersburg State Univ, StPetersburg, Russia.

72

POSTER SESSIONS Poster board number is in bold above the title. See page 15 for presentation schedule. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

683B Stable border of hunchback gene expression is formed by canalization of the Bicoid morphogen variability in the Drosophila blastoderm. Gursky Vitaly1, Manu Manu2, John Reinitz3, Alexander Samsonov1, Maria Samsonova4. 1) Theoretical Department, Ioffe Physico-Technical Institute of the Russian, St Petersburg, Russia; 2) Chicago Center for Systems Biology, University of Chicago, Chicago, USA; 3) Department of Applied Mathematics and Statistics, and Center for Developmental Genetics, Stony Brook University, Stony Brook, USA; 4) Department of Computational Biology, Center for Advanced Studies, St Petersburg State Polytechnical University, St Petersburg, Russia. 684C Self-induced Patched receptor degradation adjusts cell sensitivity to the Hedgehog morphogen gradient. Andreu Casali. Institut de Biologia Molecular de Barcelona (IBMBCSIC) and Institute for Research in Biomedicine (IRB). Baldiri Reixach 10, 08028 Barcelona, Spain. 685A The vein organizing activities of abrupt and knirps in Drosophila wing. Orna Cook, Nina Nguyen, Ethan Bier. Dept Biol, Univ California, San Diego, San Diego, CA. 686B Essential roles for the zinc finger protein Bowl in control of growth, patterning and morphogenesis of the Drosophila notum. Steven DelSignore, Victor Hatini. Anatomy Department, Tufts University School of Medicine, Boston, MA. 687C The role of CG11148 during embryogenesis and wing patterning in Drosophila. Jeanine Schibler, Vidya Chandrasekaran. Saint Mary’s College of California 1928 Saint Mary’s Road Moraga, CA 94556. 688A Reversible Phosphorylation of Smoothened Transduces Graded Hedgehog Signaling. Ying Su, Jason Ospina, Junzheng Zhang, Andrew Michelson, Adam Schoen, Alan Jian Zhu. Dept Cell Biol, NC10, Lerner Res Inst, Cleveland, OH. 689B An O-glycosyltransferase promotes cell adhesion during development by influencing secretion of an extracellular matrix integrin ligand. Liping Zhang, Duy D. Tran, Kelly G. Ten Hagen. NIDCR/NIH, Bethesda, MD.

Physiology and aging 690C Dominant-negative Dmp53 extends life span through the dTOR pathway in D. melanogaster. Johannes H. Bauer1,2, Chengyi Chang2, Gina Bae2, Siti Nur Sarah Morris2, Stephen L. Helfand2. 1) Biological Sciences, Southern Methodist University, Dallas, TX; 2) Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, RI. 691A Molecular Correlates of Life History Trade-offs. Sarah M. Morgan1,3,4, David Raubenheimer2,3, Peter K. Dearden1,3,4. 1) Genetics, C/- Dept of Biochemistry, University of Otago, PO Box 56, Dunedin 9054, New Zealand; 2) Massey University, Private Bag 102-904, Auckland, New Zealand; 3) National Research Centre for Growth & Development; 4) Genetics Otago.

692B Identifying the Effects of Resveratrol on Lifespan Extension and Gene Expression in Drosophila melanogaster. Neha Sirohi1, Alexis Nagengast2. 1) Department of Biology; 2) Department of Biochemistry, Widener University, Chester, PA. 693C Characterization of the Scavenger Receptor Class B type I (SR-BI) family in Drosophila melanogaster. Leire Herboso, Ana Talamillo, Coralia Pérez, Rosa Barrio. CIC bioGUNE, Derio, Bizkaia, Spain. 694A The nuclear receptor DHR4 regulates the termination of feeding during larval development of Drosophila melanogaster. Qiuxiang Ou, Kirst King-Jones. Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada. 695B The control of lipid storage by the circadian clock and age in Drosophila melanogaster. Justin R. DiAngelo1, Kanyan Xu1, Michael Hughes2, John Hogenesch2, Amita Sehgal1. 1) Dept Neuroscience, Univ Pennsylvania/HHMI, Philadelphia, PA; 2) Dept Pharmacology, Univ Pennsylvania, Philadelphia, PA. 696C Mito-Nuclear epistasis for longevity, fecundity, and mitochondrial function in mtDNA introgression strains of Drosophila. Marissa A. Holmbeck, Max Rubinstein, Kristi L. Montooth, Colin Meiklejohn, Dawn Abt, David Rand. Brown University, Providence, RI. 697A A dominant mutation in the fatty acid transporter-encoding gene dFatp provides increased stress resistance and lifespan extension on a wide variety of diets. Nicole M. Piazza, Samantha Morley, Joanna Jennens, Michael Hayes, Robert Wessells. Geriatrics and Internal Medicine. University of Michigan, Ann Arbor, MI. 698B Regulation of Lipid Homeostasis by the Drosophila DHR96 Nuclear Receptor. Matt Sieber, Carl Thummel. Dept Human Gen, Univ Utah, Salt Lake City, UT. 699C Lipin is a central regulator of fat body development and function in Drosophila . Rupali B. Ugrankar, Michael Lehmann. Dept Biological Sci, Univ Arkansas, Fayetteville, AR. 700A Caffeine Sensitivity in Drosophila melanogaster. Ran Zhuo, Brian Lee, Elizabeth Silva, Stanley Tiong, Kirst King-Jones, Shelagh Campbell. Biological Sciences Dept, University of Alberta, Edmonton, Alberta, Canada. 701B Nuclear Receptor DHR96 acts as a sensor for low cellular cholesterol concentrations. Akila Gopalakrishnan, Kirst King-Jones. Department of Biological Sciences CW 405, Biological Sciences Bldg. University of Alberta Edmonton, Alberta Canada T6G 2E9.

POSTER SESSIONS

73

Poster board number is in bold above the title. See page 15 for presentation schedule. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

702C Curcumin Extends Lifespan, Improves Healthspan, and Modulates the Expression of Age-Associated Aging Genes in Drosophila melanogaster. Kyung-Jin Min1, Byung-Sup Lee1, Kyu-Sun Lee2, Kwon Yu2, Chae-Yoon Um3, Hyun-Jin Jeon3, Sahar Semnani4, Agnesa Avanesian Avanesian4, Mahtab Jafari4. 1) Dept Biol Sci, Inha University, Incheon, Korea; 2) Aging Research Center, Korean Research Institute of Bioscience and Biotechnology, Daejeon, Korea; 3) Insan Daejin High School, Goyang, Korea; 4) Department of Pharmaceutical Sciences, University of California, Irvine, CA. 703A Functional Analysis of Evolutionarily-Conserved Mitochondrial Proteins in Drosophila melanogaster. Daniel K. Bricker1, Jared Rutter2, Carl S. Thummel1. 1) Department of Human Genetics, University of Utah School of Medicine, Salt Lake City, UT; 2) Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT. 704B TGF-B Signaling Regulates Drosophila Metamorphosis by Activating Expression of JHAMT, a Key Regulatory Enzyme in Juvenile Hormone Biosynthesis. Jianhua Huang1, Ling Tian2, Cheng Peng1, Mohamed Abdou1, Ying Wang1, Sheng Li2, Jian Wang1. 1) Department of Entomology, University of Maryland, College Park, MD; 2) Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China. 705C Cell intrinsic and cell extrinsic contributions to aging of Drosophila male germline stem cells. Matthew R. Wallenfang, Noor Al-Husayni, Margarita Borovka, Debbie Chen, Fahmida Islam, Sarah Ishal, Denisse Izquierdo, Sarah Nickel. Dept Biological Sci, Barnard College, New York, NY. 706A Effects of oxidative stress and aging on the transcriptional regulation of the de novo purine synthesis pathway in Drosophila melanogaster. Amy M. Botta, Denise V. Clark. Biology, University Of New Brunswick, Fredericton, New Brunswick, Canada. 707B Levels of Heat Tolerance in Drosophila melanogaster Associate With Hsp90 Level. Fiona E. Cockerell, Travis K. Johnson, Carla Sgrò, Stephen W. McKechnie, Centre for Environmental Stress and Adaptation Research (CESAR). School of Biological Sciences, Monash University, Melbourne, Australia. 708C Overexpression of the PGC1-A ortholog spargel phenotypically mimics endurance exercise training. Joanna M. Jennens, Erin Matthys, Robert Wessells. Geriatrics and Internal Medicine. University of Michigan, Ann Arbor, MI. 709A The Contribution of Starvation and Desiccation to ColdInduced Mortality in Drosophila. Robert Kobey, Jesicca Rice, Elizabeth Eggleston, Kristi Montooth. Indiana University, Bloomington, IN.

710B Transcriptional activation of novel signaling molecules in response to mitochondrial oxidative stress. Sanjay Nag, Atanu Duttaroy. Dept Biol, Howard Univ, Washington, DC. 711C Impact of body melanisation on desiccation resistance in montane populations of D. melanogaster: analysis of seasonal variation. V. Sharma, R. Parkash, K. Bhawna. Genetics, Maharshi Dyanand,University, Rohtak, India. 712A Phosphorylation of Slpr/MLK as a sensor for heat stress. Beth Stronach, Rebecca Gonda. Dept Biol Sci, Univ Pittsburgh, Pittsburgh, PA.

Regulation of gene expression 713B NMNAT to the Rescue: Understanding the Transcriptional Regulation of a Novel Neuroprotective Stress Chaperone. Yousuf O. Ali1, Ryan McCormack2, Grace Zhai1,3. 1) Molecular & Cellular Pharmacology, University of Miami, Miami, FL; 2) Program in MD/PhD, Miller School of Medicine, University of Miami, Miami, FL; 3) Neuroscience Program, Miller School of Medicine, University of Miami, FL. 714C Drosophila FTZ-F1 is required for JH activation of E75A in S2 cells. Travis J. Bernardo, Veronica Dubrovskaya, Heather Bryan, Robert DiFilippo, Edward Dubrovsky. Dept of Biol. Sciences, Fordham University, Bronx, NY. 715A The role of MEF2 in adult myogenesis. Anton Bryantsev, MaryAnn Jaramillo, Richard Cripps. Dept of Biology, University of New Mexico, Albuquerque, NM. 716B Transcriptional regulation of Enhancer of Split (E(spl)) targets by various mercury species. Julie C. Dao, Gregory Engel, Matthew D. Rand. Anatomy and Neurobiology, University of Vermont College of Medicine, Burlington, VT. 717C Chromatin Landscape Dictates Heat Shock Factor Binding to its Target DNA Elements. Michael J. Guertin, John T. Lis. Molecular Biology and Genetics, Cornell University, Ithaca, NY. 718A A Molecular Mechanism of Temperature Sensitivity for Mutations Affecting the Drosophila Muscle Regulator Myocyte Enhancer Factor-2. TyAnna L. Lovato, Melanie M. Adams, Phillip W. Baker, Melody M. Martinez, Richard M. Cripps. Biol, Univ New Mexico, Albuquerque, NM. 719B Transcriptional regulation of the purine de novo synthesis gene Prat in Drosophila melanogaster. Eric M. Merzetti. University of New Brunswick, Fredericton, New Brunswick, Canada.

74

POSTER SESSIONS Poster board number is in bold above the title. See page 15 for presentation schedule. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

720C Akirin links Twist transcription with the Brahma chromatin remodeling complex during embryogenesis. Scott J. Nowak1, Hitoshi Aihara2, Katie Gonzalez3, Yutaka Nibu2, Mary K. Baylies1. 1) Developmental Biology, Sloan Kettering Institute, New York, NY 10065; 2) Cell and Developmental Biology, Weill Cornell Medical College, New York, NY 10065; 3) Molecular Diagnostic Services, Inc, San Diego, CA. 721A Identification of Protein Cofactors of Drosophila Myb by Biotin-tagging. Choon Kiat Sim, Joe Lipsick. Department of Pathology, L216, Stanford University School of Medicine, 300 Pasteur Drive Stanford, CA 94305-5324.

729C Transcription Start Sites and Promoter Architecture in the D. melanogaster Embryo. Jane Landolin1, Roger Hoskins1, Jeremy Sandler1, Timo Lassmann2, Benjamin Booth1, Lucy Cherbas3, Charles Yu1, Kenneth Wan1, Li Yang4, Nathan Boley5, Peter Bickle5, Peter Cherbas3, Brenton Graveley4, Piero Carninci2, Joseph Calrson1, Susan Celniker1. 1) Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA; 2) RIKEN Institute, Yokohama, Japan; 3) Dept. Biology and Center for Genomics and Bioinformatics, Indiana University, Bloomington, IN; 4) Dept. Genetics and Developmental Biology, University of Connecticut Health Center, Farmington, CT; 5) Dept. Statistics, University of California, Berkeley, CA.

722B A potential role of dMyc in cell fate determination during the differentiation of the Drosophila eye. Vimala Baksh, Paola Bellosta. Biology, City College of New York, New York, NY.

730A The role of Zelda as a timer of the maternal to zygotic transition in Drosophila embryos. Hsiao-Lan Liang, Rachael Barry, Christine Rushlow. Biology, New York Univ, New York, NY.

723C Integrated genome analysis of genetic networks regulated by eyeless during retinal development in Drosophila. Yiyun Chen, Yumei Li, Hui Wang, Bryce Daines, Xingzhi Song, Keqing Wang, Rui Chen. Human Genome Sequencing Center, Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX.

731B Iro-C genes regulate lateral transverse muscle identity by modulating the expression of downstream target genes. Antonio S. Tutor1, Marta Carrasco-Rando1, Silvia Prieto-Sánchez1, Esther González-Pérez1, Natalia Barrios1, Analisa Letizia2, Sonsoles Campuzano1, Mar Ruiz-Gómez1. 1) Centro de Biología Molecular Severo Ochoa. Spanish National Research Council. Madrid, Spain; 2) IBMB, Spanish National Research Council. Barcelona, Spain.

724A Maintenance of neuronal differentiation in adult neurons. Kevin T. Eade, Douglas W. Allan. Cellular and Physiological Sciences, University of British Columbia, Vancouver, British Columbia, Canada. 725B The updated BDGP genome-wide embryonic spatial gene expression pattern resource includes a completed set of transcription factors. Erwin Frise, Ann Hammonds, Bill Fisher, Richard Weiszmann, Susan Celniker. BDGP, Lawrence Berkeley Nat Lab, Berkeley, CA. 726C Identifing Zelda-regulated early zygotic microRNAs in Drosophila embryo. Shengbo Fu, Chung-Yi Nien, Hsiao-Lan Liang, NiKolai Kirov, Christine Rushlow. Biol, New York Univ, New York, NY. 727A Genetic Epistasis Analysis of dMyc With the Amino Acid Transporter mnd. Mina Girgis, Eunice Anderson, Carlina Lora, Lulu Nanogi, Paola Bellosta. Biology, City College of New York, New York, NY. 728B Investigating dmyc cis-regulatory elements by studying reporter activity: site specific phage FC31 system versus random P-Element insertion. Jasmine Kharazmi1, Hans Peter Lipp2. 1) Molec Biol Lab, Biotech Ctr Zurich, Zurich, Switzerland; 2) Institute of Anatomy, University of Zurich, Winterthurerstrasse 190, CH-8055 Zurich, Switzerland.

732C Shared cis-acting elements mediate Capicua-dependent repression of terminal gap genes. Leiore Ajuria1, Claudia Nieva1, Núria Samper1, Aharon Helman2, Sergio GonzálezCrespo1, Ze’ev Paroush2, Gerardo Jiménez1,3. 1) IBMBCSIC, Parc Científic de Barcelona, Barcelona 08028, Spain; 2) Department of Developmental Biology and Cancer Research, IMRIC, Faculty of Medicine, The Hebrew University, Jerusalem 91120, Israel; 3) Institució Catalana de Recerca i Estudis Avançats, Barcelona 08010, Spain. 733A Identification of cis-regulatory elements of D. melanogaster TpnC41C gene required for its muscle-specific expression. Maria Chechenova, TyAnna Lovato, Richard Cripps. Biol, Univ New Mexico, Albuquerque, NM. 734B Mechanisms of transcriptional repression in the Drosophila embryo: Anti-looping and Pol II stalling. Vivek S. Chopra, David Hendrix, Nikki Kong, Michael Levine. Department of Molecular & Cell Biology, University of California Berkeley, Berkeley, CA. 735C REDfly: The Regulatory Element Database for Drosophila. Marc S. Halfon1,2, Steven M. Gallo1,2, Michael Simich1, Dave T. Gerrard3, Casey M. Bergman3. 1) SUNY at Buffalo, Buffalo, NY; 2) NYS Center of Excellence in Bioinformatics & Life Sciences, Buffalo, NY; 3) University of Manchester, Manchester, UK.

POSTER SESSIONS

75

Poster board number is in bold above the title. See page 15 for presentation schedule. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

736A The Boundary Element-Associated Factors BEAF-32A and BEAF-32B affect regulation of genes in the Antennapedia complex. Craig M. Hart1, Swarnava Roy1,2, Nan Jiang1,3. 1) Dept Biological Sci, Louisiana State Univ, Baton Rouge, LA; 2) NIDDK, NIH, Bethesda, MD; 3) Dept Molec Biol, Cell Biol and Biochem, Brown Univ, RI. 737B Analysis of specific cis-regulatory elements of the repo locus in Drosophila. Robert W. Johnson, Jamie L. Wood, Bradley W. Jones. Department of Biology, The University of Mississippi, Oxford, MS. 738C Probing the Structural Complexity of a Temporally Regulated Neuroblast Enhancer. Alexander B. Kuzin, Mukta Kundu, Thomas Brody, Ward Odenwald. Neural Cell-Fate Determinents Section, NINDS/NIH, Bethesda, MD. 739A Spatial regulation of achaete via global activation and repression by Hairy and Delta. Ji Inn Lee, Meghana Joshi, Teresa Orenic. Dept Biological Sci, Univ Illinois, Chicago, Chicago, IL. 740B A cis-regulatory map of the Drosophila genome. Nicolas Negre1, Casey Brown1, Rebecca Spokony1, Ulrich Wagner4, Zirong Li4, Haruhiko Ishi4, Steve Miller4, Pouya Kheradpour5, Steve Bristow5, Nick Bild1, Carolyn Morriso1, Jennifer Zieba1, Sarah Suchy1, Jia Chen2, Marc Domanus3, Jim Posakony4, Bing Ren4, Robert Grossman2, Manolis Kellis5, Kevin White1. 1) IGSB, Univ Chicago, Chicago, IL; 2) UIC, Chicago, IL; 3) Argonne National Lab, Argonne, IL; 4) UCSD, San Diego, CA; 5) MIT, Cambridge, MA. 741C Deciphering cis-regulation in different adult muscle subgroups: enhancers for IFM-specific genes. Cloyce E. Nelson, Anton Bryantsev, Tyanna Lovato, Richard M. Cripps. Biol, Univ New Mexico, Albuquerque, NM. 742A Shadow enhancers in the anterior-posterior patterning system. Michael W. Perry1, Alistair N. Boettiger2, Michael Levine3. 1) Department of Integrative Biology, UC Berkeley, Berkeley, CA 94720; 2) Biophysics Program, UC Berkeley, Berkeley, CA 94720; 3) Department of Molecular & Cell Biology, Division of Genetics, Genomics, and Development, Center for Integrative Genomics, UC Berkeley, Berkeley, CA. 743B Prediction and global analysis of BMP target genes. George Pyrowolakis1, Alisa Fuchs1, Anaïs Flore Bardet2, Enrica Charbonnier1, Robin Vuilleumier1, Alex Weiss3, Markus Affolter3, Alexander Stark2. 1) Biology I, University of Freiburg, Germany; 2) IMP, Vienna, Austria; 3) Biozentrum, University of Basel, Switzerland.

744C Deletion and bioinformatic analyses of the promoter region of the enhancer of rudimentary gene reveal that zeste is a transcriptional activator of e(r). Nicholas P. Rizzo1,2, Zehu Tan3, Hannah J. Cushman1, Stuart I. Tsubota1. 1) Biology, The College at Brockport, SUNY, Brockport, NY; 2) Biology, University of Rochester, Rochester, NY; 3) Biology, Saint Louis University, St. Louis, MO. 745A Dissecting the cis-regulatory enhancers that control pdm-1 and pdm-2 neuroblast gene expression. Jermaine Ross1,2, Thomas Brody1, Mukta Kundu1, Alexander Kuzin1, Ward F. Odenwald1. 1) Neural Cell-Fate Determinants Section, NINDS, NIH, Bethesda, MD; 2) Brown University, Providence, RI. 746B seven-up is expressed in the founder cells of a subset of somatic muscles in Drosophila melanogaster and is required for their formation. Kathryn M. Ryan, Grace A. Mason, Richard M. Cripps. Dept Biol, Univ New Mexico, Albuquerque, NM. 747C Flexible configurations of binding sites mediate Hox complex formation with Extradenticle and Homothorax on DNA. Juli D. Uhl1, Tiffany Cook1,2, Brian Gebelein1. 1) Developmental Biology, Cincinnati Children’s Hospital, Cincinnati, OH; 2) Pediatric Ophthalmology, Cincinnati Children’s Hospital, Cincinnati, OH. 748A A transcriptional repressor Blimp-1 works as an hourglass timer during metamorphosis. Kazutaka Akagi1, Moustafa Sarhan1, Hitoshi Ueda1,2. 1) Grad sch, Nat Sci and Tech, Okayama Univ, Okayama, Japan; 2) Dept Biol, Fac Sci, Okayama Univ, Okayama, Japan. 749B Towards a Comprehensive Map of Embryonic Transcription Factor Expression Patterns. Chris A. Bristow1,2,5, Ann Hammonds3,5, Kheradpour Pouya1, Volker Hartenstein4, Erwin Frise3, Richard Weiszmann3, Bill Fisher3, Manolis Kellis1,2, Sue Celniker3. 1) Computer Science, MIT, Cambridge, MA; 2) Broad Institute of MIT and Harvard, Cambridge, MA; 3) Department of Genome and Computational Biology, Lawrence Berkeley National Laboratory, Berkeley, CA; 4) Department of Molecular Cell and Developmental Biology, University of California, Los Angeles, CA; 5) These authors contributed equally to this work. 750C micro RNAs play a role in the regulation of the Drosophila female mating response. Ido Carmel1, Sandra L. Schnakenberg2, Mark L. Siegal2, Yael Heifetz1. 1) Department of Entomology, Hebrew University, Rehovot, Israel; 2) Department of Biology, New York University, New York, NY. 751A CAGE analysis of whole larval RNA. Mitchell S. Dushay1, Yizhi Zhang2, Eric Bremer3. 1) Biology Division, Illinois Inst Tech, Chicago, IL; 2) Applied Mathematics, IIT, Chicago, IL; 3) Precision Biomarker Resources, Inc, Evanston, IL. 752B Position effects on transposable element remobilization. Caroline Esnault, Kristina Pilitt, David O’Brochta. CARB UMBI, Rockville, MD.

76

POSTER SESSIONS Poster board number is in bold above the title. See page 15 for presentation schedule. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

753C Requirement of male-specific dosage compensation in Drosophila females. Jamila I. Horabin, Natalie Gladstein, Meghan McKeon. Dept Biomedical Sciences, Florida State Univ, Tallahassee, FL. 754A The identification of Drosophila regulatory motif instances and their characterization in relation to chromatin marks and transcription factor binding. Pouya Kheradpour1, Jason Ernst1, Christopher Bristow1, Rachel Sealfon1, Alexander Stark3, Manolis Kellis1,2. 1) Computer Science and Artificial Intelligence Lab, MIT, Cambridge, MA; 2) Broad Institute of MIT and Harvard, Cambridge, MA; 3) Research Institute of Molecular Pathology (IMP), Vienna, Austria. 755B Global regulation of chromatin in Drosophila melanogaster males. S. Kiran Koya1, Xinxian Deng1,3, Ying Kong1, Victoria Meller1,2. 1) Dept of Biological Sciences, Wayne State University, Detroit, MI; 2) Molecular Biology and Genetics Program, Barbara Ann Karmanos Cancer Institute, Detroit, MI; 3) Current address: Department of Pathology, University of Washington School of Medicine, Seattle, WA. 756C A time course of sex-specific transcription in early embryogenesis revealed by single embryo RNA-seq. Susan E. Lott1, Jacqueline E. Villalta2, Leath A. Tonkin3, Michael B. Eisen1,2. 1) Department of Molecular and Cell Biology, Univ California, Berkeley, CA; 2) Howard Hughes Medical Institute, Univ California, Berkeley, CA; 3) Vincent J. Coates Functional Genomics Sequencing Laboratory, Univ California, Berkeley, CA. 757A Females and males differ in response to changes in gene dose. John H. Malone1, Dong Yeon Cho2, Teresa Przytycka2, Justen Andrews3, Brian Oliver1. 1) Laboratory of Cellular and Developmental Biology, National Institute of Diabetes, Digestive, and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, 20892 USA; 2) National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Computational Biology Branch, Bethesda, MD 20894; 3) Department of Biology, Indiana University, Bloomington, IN 47405. 758B The Y chromosome is a potent modifier of X-chromosome dosage compensation. Debashish Menon, Victoria Meller. Wayne State Univ, Dept of Biological sciences, Detroit, MI. 759C Transcriptional Control of Xenobiotic Detoxification in Drosophila. Jyoti R. Misra, Michael A. Horner, Carl S. Thummel. Dept Human Gen, Univ Utah, Salt Lake City, UT. 760A Epigenetic stability increases during differentiation within the follicle stem cell lineage of the Drosophila ovary. Andrew Skora, Allan Spradling. Dept of Embrology, Carnegie Institution of Science, Baltimore, MD.

761B Interaction between physiology and circadian gene expression in the Drosophila fat body. Kanyan Xu1, Micheal Hughes2, John Hogenesch2, Amita Sehgal3. 1) Dept Neuroscience, Univ Pennsylvania, Philadelphia, PA; 2) Penn Genome Frontiers Institute Institute for Translational Medicine and Therapeutics University of Pennsylvania School of Medicine, Philadelphia, PA; 3) University of Pennsylvania Medical School 219 Stemmler Hall Philadelphia, PA. 762C The functional role of the mitochondrial transcription termination factor 3 (MTERF3) in Drosophila melanogaster. Ana M. Bratic1,2, Anna Wredenberg1,2, Rolf Wibom2, Linda Partridge1, Nils-Goran Larsson1,2. 1) Max-Planck Institute for Biology of Ageing, Gleueler Strasse 50a, D-50931, Cologne; 2) Division of Metabolic Diseases, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden. 763A En cofactor interactions that influence repression of the slp locus. Z. Cofer1, M. Fujioka1, X. Wu1, B. Gebelein2, J. B. Jaynes1. 1) Biochemistry and Molecular Biology, Thomas Jefferson Univ, Philadelphia, PA; 2) Division of Developmental Biology, Cincinnati Children‘s Hospital, Cincinnati, OH. 764B Regulation via micro-RNAs, an alternative pathway for regulation by dMyc. Kaveh Daneshvar, Abid Khan, Julie Goodliffe. Biol, UNC at Charlotte, Charlotte, NC. 765C Combinatorial Regulation of Enhancer of split HLHmgamma in Drosophila melanogaster. Deborah A. Eastman, Erica Hildebrand, Colleen Megley. Department of Biology, Connecticut College, New London, CT. 766A Repressors define both the dorsal and ventral borders of Dorsal target genes. Mayra Garcia, Angelike Stathopoulos. Division of Biology, California Institute of Technology, Pasadena, CA. 767B Drosophila microRNAs 263a/b are required during pattern formation in the developing retina to protect nascent sense organs from apoptosis. Valérie Hilgers1,3, Natascha Bushati1,4, Stephen Cohen1,2. 1) Temasek Lifesciences Laboratory, 1 Research Link, Singapore 117604; 2) Department of Biological Sciences, National University of Singapore, 1 Research Link, Singapore 117604; 3) European Molecular Biology Laboratory (EMBL), Meyerhofstr. 1, 69117 Heidelberg, Germany; 4) present address: National Institute for Medical Research Mill Hill, London, NW7 1AA, UK. 768C Sumoylation Modulates the Activity of Spalt-like Proteins in Drosophila. Jonatan Sanchez-Garcia1,2, Ana Talamillo2, Fernando Lopitz-Otsoa2, Coralia Perez2, Manuel S. Rodriguez2,3,4, Rosa Barrio2. 1) Department of Neurology, University of Florida, Gainesville, FL, 32610; 2) CIC bioGUNE, Bizkaia Technology Park, Building 801-A, 48160 DERIO, Bizkaia, Spain; 3) CIC bioGUNE-CIBERehd; 4) Biochemistry and Molecular Biology Department, University of the Basque Country, 48940 Leioa, Bizkaia, Spain.

POSTER SESSIONS

77

Poster board number is in bold above the title. See page 15 for presentation schedule. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

769A Molecular identification of single genes that produce an inverse dosage effect. Weiwu Xie, James Birchler. Biological Sci Div, Univ Missouri-Columbia, Columbia, MO.

RNA biology 770B A transposon-based genetic screen in Drosophila for miRNA pathway genes. Xiaohong Wang, Sigal Pressman, Richard Carthew. Department of Biochemistry, Molecular Biology, and Cell Biology, Northwestern University, Evanston, IL. 60208. 771C A long non-coding RNA gene is involved in the regulation of sleep homeostasis in Drosophila. Alexey A. Soshnev1, Hiroshi Ishimoto2, Bryant F. McAllister3, Xingguo Li4, Misty D. Wehling4, Toshihiro Kitamoto2, Pamela K. Geyer1,4. 1) Molecular and Cellular Biology Program, Univ Iowa, Iowa City, IA; 2) Anesthesia Dept, Univ Iowa, Iowa City, IA; 3) Biology Dept, Univ Iowa, Iowa City, IA; 4) Biochemistry Dept, Univ Iowa, Iowa City, IA. 772A Evolution and Function of long intergenic noncoding RNAs in Drosophila. Robert S. Young, Chris P. Ponting, Ji-Long Liu. MRC Functional Genomics Unit, Dept. Physiology, Anatomy and Genetics, Oxford, United Kingdom. 773B Mechanisms and Functions of SMAUG in Posttranscriptional Regulation. Linan E. Chen1, Xiao Li1, Craig Smibert1,2, Howard Lipshitz1. 1) Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; 2) Biochemistry, Univeristy of Toronto, Toronto, Ontario, Canada. 774C Bicaudal-C and Ccr4 repress nanos expression during oogenesis. Chiara Gamberi, Paul Lasko. Dept Biol, McGill Univ, Montreal, PQ, Canada. 775A Post-transcriptional regulation of maternal RNAs by PUMILIO in Drosophila melanogaster. Mariana Kekis1, Hua Luo1, Timothy R. Hughes1,2, Howard D. Lipshitz1. 1) Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada; 2) Banting and Best Department of Medical Research, University of Toronto, Toronto, ON, Canada. 776B Translational regulation of gurken (grk) mRNA during oogenesis. Amanda Norvell, Young Il-Seo. Dept Biol, Col of New Jersey, Ewing, NJ. 777C A Novel Zinc-Finger RNA-Binding Protein in Drosophila That Regulates Poly(A)-Tail Length And Neuronal Function. Changhui Pak1,2,4, Seth Kelly2, Luciano Apponi3, Brenda Huang4, Sara Stahley5, Anita Corbett2, Kenneth Moberg1. 1) Dept. of Cell Biology, Emory Univ Sch Med, Atlanta, GA; 2) Dept. of Biochemistry, Emory Univ Sch Med, Atlanta, GA; 3) Dept. of Pharmacology, Emory Univ Sch Med, Atlanta, GA; 4) Graduate program in Genetics and Molecular Biology, Emory Univ Sch Med, Atlanta, GA; 5) Graduate program in Biochemistry, Cell and Developmental Biology, Emory Univ Sch Med, Atlanta, GA.

778A Analysis of tissue-specific requirements for the nonsense mediated mRNA decay pathway. Alex Chapin, Mark M. Metzstein. Department of Human Genetics, Univ Utah, Salt Lake City, UT 84112. 779B Analysis of nonsense mediated decay transcript targeting in vivo. Kimberly A. Frizzell, Shawn Rynearson, Mark M. Metzstein. Dept Human Genetics, Univ Utah, Salt Lake City, UT. 780C Identification of a cup-dependent mRNA localization pathway for the early oocyte. Risa Broyer, Elena Monfort-Prieto, James Wilhelm. Section on Cell and Developmental Biology, UC San Diego, La Jolla, CA. 781A Does the Cajal body play a role in regulating the Gypsy retrotransposon? Daniel Escobar, Joseph Gall. Carnegie Institution of Washington Dept. of Embryology 3520 San Martin Drive Baltimore, MD 21218. 782B Determinants of RNA Localisation Efficiency in the Drosophila Oocyte. David J. Finnegan1, Eve Hartwood1, James C. Brodie1, Georgia Vendra1,3, Ilan Davis1,2. 1) Institute of Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom; 2) Department of Biochemistry, University of Oxford, Oxford, United Kingdom; 3) Department of Neuronal Cell Biology, Medical University of Vienna. 783C Splicing and a novel cis-acting element control oskar mRNA localization in the Drosophila oocyte. Sanjay Ghosh, Virginie Marchand, Alvar Trucco, Anne Ephrussi. Dev Biol, European Molec Biol Lab, Heidelberg, Germany. 784A The GLS stem-loop is required for Drosophila gurken mRNA localization and message stability. Lan Lan1, Shengyin Lin2, Robert Cohen1. 1) Dept Molec Biosci, Univ Kansas, Lawrence, KS; 2) Dept Neuroscience, Univ Toledo Med Ctr, Toledo, OH. 785B Lost and Rump interact to mediate maternal mRNA localization. Kristina S. Sinsimer, Roshan A. Jain, Elizabeth R. Gavis. Molecular Biology, Princeton University, Princeton, NJ. 786C Cajal body mutants have properly processed splicing snRNAs and normal histone locus bodies. Svetlana Deryusheva, Zehra Nizami, Joseph Gall. Embryology, Carnegie Institution, Baltimore, MD. 787A Evidence for alternative splicing in the complex Drosophila dumpy gene. Amber Carmon, Ross MacIntyre. Dept Molec Biol & Genetics, Cornell Univ, Ithaca, NY. 788B The Control of Lipid Metabolism by Splicing in Drosophila. Thomas J. Carr Jr.1, Timothy Rudolph1, Neha Sirohi2, Justin DiAngelo3, Alexis Nagengast1. 1) Dept Biochemistry; 2) Dept Biology, Widener University, Chester, PA; 3) Dept Neuroscience/HHMI, University of Pennsylvania School of Medicine, Philadelphia, PA.

78

POSTER SESSIONS Poster board number is in bold above the title. See page 15 for presentation schedule. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

789C Mechanism of a U1snRNA-dependent Regulatory Module. Michael Y. Chen, Panagiotis Papasaikas, Stephanie Hughes, A. Javier Lopez. Dept Biological Sci, Carnegie Mellon Univ, Pittsburgh, PA. 790A RNA electrophoretic mobility shift analysis of Drosophila rnp-4f splicing assembly factor 5’-UTR intron splicing regulation by dADAR isoforms. Girija Lakshmi, Gabriel Jones, Jing Chen, Jack Vaughn. Zoology Department, Miami University, Oxford, OH.

Stem cells 791B HnRNP Poly(ADP-ribosyl)ation is Required During Drosophila Oogenesis. Yingbiao Ji, Alexei Tulin. Dept Basic Sci, Fox Chase Cancer Ctr, Philadelphia, PA. 792C Elucidating the role of the Drosophila CIAPIN1-like protein in Fe/S cluster biogenesis and its function in stem cell maintenance. Gabriella Peretz, Anya Bakhrat, Uri Abdu. Dept Life Sci, Ben-Gurion Univ, Beer-Sheva, Israel. 793A The role of insulin signaling and nutrition in the regulation of Drosophila male germline stem cells. Therese M. Roth1, C.-Y. Ason Chiang1, Caitlin E. Roth1, Yukiko M. Yamashita1,2. 1) Life Sci Inst (5183), Univ Michigan, Ann Arbor, MI; 2) Dept of Cell and Developmental Biology, Univ Michigan, Ann Arbor, MI. 794B Systematic functional characterization of histone demethylases and histone deacetylases in germline stem cells. Nevine A. Shalaby, Shane Scoggin, Susan Eliazer, Dhananjay Chatuvedi, Michael Buszczak. Molecular Biology, UTSouthwestern Medical Center at Dallas, Dallas, TX. 795C The ISWI-containing chromatin remodeling complex NURF maintains Drosophila ovarian germline stem cells. Pei Wen1,2, Rongwen Xi1. 1) National Institute of Biological Sciences, Beijing, China; 2) College of Life Sciences, Beijing Normal University, Beijing, China. 796A Male germline stem cells in the Drosophila testis do not asymmetrically segregate chromosome strands. Swathi Yadlapalli, Yukiko M. Yamashita. Center for Stem Cell Biology, Life Sciences Institute; Dept of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI. 797B Function of CG2264 in Drosophila male germline stem cell maintenance. Qi Zheng1, Yiwen Wang2, Eric Vargas2, Stephen DiNardo2. 1) Department of Biology, University of Pennsylvania, School of Arts and Sciences, Philadelphia, PA; 2) Cell and Developmental Biology, University of Pennsylvania, School of Medicine, Philadelphia, PA. 798C Lsd1 controls the size of the Drosophila Germline Stem Cell Niche. Susan Eliazer, Michael Buszczak. Molecular Biology Department, University of Texas Southwestern Medical Center, Dallas, TX.

799A Btk29A-dependent tyrosine phosphorylation of Armadillo/Bcatenin is essential for soma-to-germ signaling in Drosophila oogenesis. Noriko Hamada-Kawaguchi1, Beston F. Nore2, C. I. Edvard Smith2, Daisuke Yamamoto1. 1) Department of Developmental Biology and Neurosciences, Tohoku University Graduate School of Life Sciences, Sendai 980-8578, Japan; 2) Karolinska Institutet, Clinical Research Center at Novum, Karolinska University Hospital Huddinge, SE-141 86 Huddinge, Sweden. 800B Target of Rapamycin modulates ovarian stem cell activity, and the proliferation, growth and survival of their progeny. Leesa M. LaFever1,2, Alexander I. Feoktistov1, Hwei-Jan Hsu1,2, Daniela Drummond-Barbosa1,2. 1) Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, TN; 2) Department of Biochemistry and Molecular Biology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD. 801C Are there stem cells in the regeneration blastema of imaginal discs? Anne E. Sustar1, Marianne Bonvin Cuddapah2, Gerold Schubiger1. 1) Dept Biology, Univ Washington, Seattle, WA; 2) Fred Hutchinson Cancer Research Center, Seattle, WA. 802A PIAS, a negative regulator of JAK-STAT signaling, regulates stem cell function in the Drosophila testis. Margaret de Cuevas, Erika Matunis. Department of Cell Biology, Johns Hopkins School of Medicine, Baltimore, MD. 803B Tuberous Sclerosis Complex restricts the growth but promotes the division of intestinal stem cells in Drosophila. Alla Amcheslavsky1, Naoto Ito1, Jin Jiang2, Tony Ip1. 1) Program in Molecular Medicine University of Massachusetts Medical School Worcester, MA 01605, USA; 2) Center for Developmental Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390. 804C A circuit discriminating somatic stem cells and niche cells in the testis. Tishina C. Okegbe1,2, Natalie Terry1, Sarah Freilich1, Lindsey Wingert1, Stephen DiNardo1,2. 1) Cell & Developmental Biology, University of Pennsylvania, School of Medicine, Philadelphia, PA; 2) The Institute for Regenerative Medicine, University of Pennsylvania, Philadelphia, PA. 805A Investigating Cell fate decisions of the Adult Intestinal Stem Cell. Carolina N. Perdigoto, Francois Schweisguth, Allison Bardin. Dev Biol Dept, Pasteur Inst, Paris, France.

Techniques and functional genomics 806B ChIP-chip and ChIP-seq of GFP-tagged transcription factors: A case study of caudal binding sites. Rebecca F. Spokony1, Nicolas Nègre1, Christopher D. Brown1, Koen Venken2, Carolyn A. Morrison1, Nicholas A. Bild1, Michael Ludwig1, Sarah Suchy1, Jennifer Zieba2, Hugo Bellen1, Kevin White1. 1) Institute for Genomics and Systems Biology, Univ Chicago, Chicago, IL; 2) Department of Molecular and Human Genetics, BCM, Houston, TX.

POSTER SESSIONS

79

Poster board number is in bold above the title. See page 15 for presentation schedule. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

807C Doublesex Occupancy Determined by ChIP-seq. Renhua Li, Leonie Hempel, Yu Zhang, David Sturgill, Brian Oliver. NIDDK/NIH, Bethesda, MD. 808A Promoter targeting preferences of the Drosophila melanogaster P-element. Casey M. Bergman, Raquel Linheiro. Faculty of Life Sciences, University Manchester, Manchester, United Kingdom. 809B Dissecting the Genetic Basis of Complex Traits in D. sechellia. Eric J. Earley, Corbin Jones. Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC. 810C T-LEX: Transposable element frequency estimate using soLEXa data. Anna-Sophie Fiston-Lavier, Matthew Carrigan, Dmitri Petrov, Josefa González. biology, Stanford University, Stanford, CA. 811A FlyExpress: A Platform for Discovering Co-expressed Genes via Comparative Image Analysis of Spatial Patterns in Drosophila Embryogenesis. Charlotte Konikoff1,2, Sudhir Kumar1,2, FlyExpress Consortium. 1) School of Life Sciences, Arizona State Univ, Tempe, AZ; 2) Center for Evolutionary Functional Genomics, Biodesign Institute, Arizona State Univ, Tempe, AZ. 812B Evaluation of splice junction detection in RNA-SEQ data with simulated reads. David Sturgill1, ModENCODE Consortium2, Brian Oliver1. 1) NIDDK/NIH, Bethesda, MD; 2) http://www. modencode.org. 813C Completion of the Bloomington Deletion Project and release of a new molecularly defined Deficiency Kit. Kevin Cook, Stacey Christensen, Thom Kaufman, Kim Cook. Bloomington Drosophila Stock Center, Dept Biol, Indiana Univ, Bloomington, IN. 814A A High Resolution Map of the Drosophila Transcriptome by Paired-End RNA-Sequencing. Bryce Daines1, Liguo Wang3, Hui Wang1,2, Yumei Li1,2, David Emmert4, William Gelbart4, Wei Li3,5, Rui Chen1,2, Flybase Consortium. 1) Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX; 2) Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX; 3) Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX; 4) Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA; 5) Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX. 815B Investigation of Mcm10 interactions using a novel yeast threehybrid approach. Jennifer Apger, Tim Christensen, Michael Reubens. Department of Biology, East Carolina University, Greenville, NC.

816C A Protein Complex Map of the Drosophila melanogaster Interactome. Robert Obar1, Jean-François Rual1, Guruharsha Kuthethur1, Bo Zhai1, Julian Mintseris1, Pujita Vaidya1, Namita Vaidya1, Saumini Shah1, Mark Stapleton2, Kenneth Wan2, Bayan Parsa2, Joseph Carlson2, Xiao Chen2, Bhaveen Kapadia2, Charles Yu2, K. VijayRaghavan3, Steven Gygi1, Susan Celniker2, Spyros Artavanis-Tsakonas1. 1) Dept of Cell Biology, Harvard Medical School, Boston, MA, 02115, USA; 2) Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA; 3) National Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore 560065, India. 817A Comparative PCR-assay of D. melanogaster vg gene mutations induced by G-rays and neutrons. Kristina Afanasieva, Igor Alexandrov, Margarita Alexandrova. Joint Institute for Nuclear Research, Dubna, Russian Federation. 818B Expanding the coverage and versatility of the Gene Disruption Project collection. Robert W. Levis1, Koen J. T. Venken2, Yuchun He2,3, Joseph W. Carlson4, Martha Evans-Holm4, Karen L. Schulze2,3, Roger A. Hoskins4, Allan C. Spradling1,3, Hugo J. Bellen2,3. 1) Dept Embryology, Carnegie Inst Science, Baltimore, MD; 2) Dept Molecular & Human Genetics, BCM, Houston, TX; 3) HHMI; 4) Dept Genome Dynamics, Lawrence Berkeley National Laboratory, Berkeley, CA. 819C Unusual molecular picture of radiation mutagenesis at the small black gene of Drosophila melanogaster. Liliana Namolovan, Igor Alexandrov, Margarita Alexandrova. Joint Institute for Nuclear Research, Dubna, RU, Russian Federation. 820A Purification of Drosophila plasma membrane: A head membrane sub-proteome. Mansi R. Khanna1, Bruce A. Stanley2, Graham H. Thomas1. 1) Biology and BMB, The Pennsylvania State University, University Park, PA; 2) Section of Research Resources, Pennsylvania State University College of Medicine, Hershey, PA. 821B Data in FlyBase: Have your say! Peter McQuilton, Gillian Millburn, Steven Marygold, The FlyBase Consortium. Genetics, Univ Cambridge, Cambridge, United Kingdom. 822C Substantially better yields of intact embryonic nuclei through optimized preparation. David Molnar, Boris Adryan. Cambridge Systems Biology Centre & Department of Genetics University of Cambridge Tennis Court Road, Cambridge, CB2 1QR, United Kingdom. 823A Drosophila TransgeneOme 1.0 - a platform for genome scale tag based protein function analysis. Mihail S. Sarov1, Radoslav Ejsmont2, Pavel Tomacak2. 1) TransgeneOmics, MPI-CBG, Dresden, Germany; 2) MPI-CBG, Dresden, Germany.

80

POSTER SESSIONS Poster board number is in bold above the title. See page 15 for presentation schedule. The first author is the presenter. Full abstracts can be found online at www.drosophila-conf.org

824B Tools to examine phospho-specific signaling in Drosophila. Richelle Sopko1,2, Mona Moghimi1,2, Jayson Baum3, Kristen Cullen3, Peter Hornbeck3, Jon Kornhauser3, Christopher Salvadore3, Roby Polakiewicz3, Kate Crosby3, Randall Wetzel3, Norbert Perrimon1,2. 1) Department of Genetics, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA; 2) Howard Hughes Medical Institute, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA; 3) Cell Signaling Technology, 3 Trask Lane, Danvers, MA 01923, USA. 825C The Drosophila Gene Collection: Status and Uses for Functional Genomics. Kenneth H. Wan, Charles Yu, Ben Booth, Joe Carlson, Xiao J. Chen, Ann Hammonds, Jane Landolin, Soo Park, Jeremy Sandler, Richard Weiszmann, Roger Hoskins, Susan Celniker. Dept of Genome Dynamics, Lawrence Berkeley National Lab, Berkeley, CA. 826A Light-mediated activation reveals a key role for Rac in collective guidance of cell movement in vivo. Xiaobo Wang1, Li He1, Yi Wu2, Klaus Hahn2, Denise Montell1. 1) Biological Chemistry, Johns Hopkins Sch Med, Baltimore, MD; 2) epartment of Pharmacology,Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill Chapel Hill, NC. 827B “The Ultimate System” for generating reporters in Drosophila. Radoslaw K. Ejsmont, Pavel Tomancak. Tomancak Lab, MPICBG, Dresden, Germany. 828C inSITE: A genetically convertible enhancer trap system for combinatorial dissection of expression patterns. Daryl Gohl, Thomas Clandinin. Dept. of Neurobiology, Stanford University, Stanford, CA. 829A Recombineering - Making High-Copy Number DNA Vectors without Restriction Enzymes and DNA Ligase. Zachary T. Robbins, Matthew O. Garringer, Hitesh Kathuria. School of Natural Science and Mathematics, Indiana University East, Richmond, IN. 830B The TRiP: The Transgenic RNAi Project at Harvard Medical School. Laura Holderbaum1, Donghui Yang-Zhou1, Jian-qian Ni1, Luping Liu1, Norbert Perrimon1,2, Lizabeth Perkins1,3. 1) Harvard Medical School, Department of Genetics, Boston, MA 02115; 2) Howard Hughes Medical Institute; 3) Pediatric Surgical Research Labs, Mass. General Hospital, Boston MA 02114. 831C Who said off-targets were so bad? Exploiting the many targets of miRNAs to screen the whole genome with only 150 crosses. Michele Markstein1, William Yee2, Djade Soumana1, Leslie Kim1, Michael Schnall-Levin2, Eric Lai3, Norbert Perrimon1. 1) Harvard Medical School, Boston, MA; 2) MIT, Cambridge, MA; 3) Memorial Sloan Kettering Cancer Center, NY, NY.

832A Permeabilization of Drosophila embryos for introduction of small molecules. Matthew D. Rand, Alison L. Kearney, Julie Dao, Todd Clason. Dept Anatomy Neurobiology, Univ Vermont, Burlington, VT.

Educational initiatives 833B Comparative Genomic Analysis of the Drosophila Dot Chromosome. Julie T. Bryant, Susan Parrish. Biology, McDaniel College, Westminster, MD. 834C The Genomics Education Partnership: Bringing Genomics into the Undergraduate Curriculum in Diverse Settings. SCR Elgin1, M. Burg2, V. Chandrasekaran3, HM Chung4, D. Dorer5, D. Johnson6, CJ Jones7, L. Kadlec8, SC Silver Key9, G. McNeil10, A. Nagengast11, DW Paetkau12, S. Parrish13, S. Smith14, J. Stamm15, M. Wawersik16, L. Zhou17, W. Leung1, C. Shaffer1, D. Lopatto18. 1) Washington Univ-St Louis MO; 2) Grand Valley St Univ MI; 3) St Mary’s Coll CA; 4) Univ West Florida FL; 5) Hartwick Coll NY; 6) George Washington Univ DC; 7) Moravian Coll PA; 8) Wilkes Univ PA; 9) NC Central Univ NC; 10) York Coll CUNY NY; 11) Widener Univ PA; 12) St Mary’s Coll IN; 13) McDaniel Coll MD; 14) Arcadia Univ PA; 15) Univ Evansville IN; 16) Coll William & Mary VA; 17) Univ Pittsburgh PA; 18) Grinnell Coll IA. 835A Annotation of a 49 kb segment of the Drosophila erecta Dot Chromosome. Jana Langley, Micah Shelton, Susan Parrish. Biology, McDaniel College, Westminster, MD. 836B Negative synergistic epistasis in Drosophila melanogaster. Ronny C. Woodruff, Caitlin M. Rex, Sarah J. Rossiter, Amanda C. Lyons. Dept Biol Sci, Bowling Green State Univ, Bowling Green, OH. 837C The instability of overdominance due to beneficial mutations. Ronny C. Woodruff. Dept Biol Sci, Bowling Green State Univ, Bowling Green, OH. 838A Rare male mating advantage in Drosophila melanogaster. Ronny C. Woodruff, Jennifer L. Benson, Adam M. Boulton, Amanda C. Lyons, Sarah J. Rossiter. Dept Biol Sci, Bowling Green State Univ, Bowling Green, OH. 839B The Drosophila erecta Dot Chromosome: A Collaborative Annotation. Bryan Yarrington, Sarah Hirsch, Susan Parrish. Biology, McDaniel College, Westminster, MD.

SPEAKER AND AUTHOR INDEX

81

This index includes name of speakers for the Opening General Session and for Plenary Sessions I and II, and names of all authors of programmed abstracts. The number following an author’s name refers to the abstract program number. A, B, or C following a number indicates a poster presentation. The presenting author of an abstract is noted with an asterisk. Please note that the complete text of abstracts is available online at www.drosophila-conf.org

A Abdilleh, Kawther, ...................... 430A* Abdou, Mohamed, ....................... 704B Abdu, Uri, ......................... 160A, 166A, 168C, 246C, 792C Abmayr, Susan, ........................... 226A Abmayr, Susan M., ...... 53, 315C, 341B Abreu-Blanco, Maria T., .................. 30* Abt, Dawn, ................................... 696C Adams, Melanie M.,..................... 718A Adelman, Karen,.............................152 Adler, Paul, ........................ 162C, 197B Adryan, Boris, .............................. 822C Afanasieva, Kristina, ................... 817A* Affolter, Markus,................. 349A, 743B Afolter, Markus,............................ 163A Ahmed, Yashi, .................... 242B, 244A Aigouy, Benoit,....................................1 Aihara, Hitoshi, ............................ 720C Aït-Ahmed, Ounissa, ................... 316A Ajuria, Leiore, .............................732C* Akagawa, Hiromi, ............ 264C*, 269B Akagi, Kazutaka,......................... 748A* Akbar, Mohammed A., .................. 150* Albanese, Nathaniel, ................... 302B Aldrich, John C., ......................... 317B* Alekseyenko, Artyom, ................. 337A, 344B, 350B Alexandrov, Igor, ................817A, 819C Alexandrov, Theodore,................. 682A Alexandrova, Margarita,.....817A, 819C Alfonso, Catalina,........................318C* Algazeery, Ahmed, ...................... 316A Al-Husayni, Noor,......................... 705C Ali, Sameh, .................................. 416B Ali, Yousuf O.,.............................. 713B* Allan, Douglas, ............................ 635B Allan, Douglas W., ............. 598A, 724A Allott, Melinda L., ......................... 311B Altenhein, Benjamin,...................627C* Amcheslavsky, Alla, .................... 803B* Amesoli, C., ................................ 157A* Ammana, Hima,........................... 409A Anderl, Ines, ................................ 556A Anderson, David, ............................148 Anderson, Eunice, ....................... 727A Andrew, Deborah,........72, 481A, 483C Andrew, Deborah J., .............. 51, 241A Andrews, Justen, ......................... 757A Andreyeva, Evgenia N., ............... 332B Andrianov, Boris V.,...................... 440B Angelini, David R., ............................ 9* Anholt, Robert, .................. 603C, 607A Anholt, Robert R. H., ......... 467B, 601A Anjum, Saima Ghafoor, .............. 553A* Annaert, Wim,.............................. 188B Antoniewski, Christophe, ..........88, 127 Antonio, Christian W., .................279C*

Apel, Ido, .................................... 239B* Apger, Jen, .................................. 336C Apger, Jennifer,........................... 815B* Apidianakis, Yiorgos, .................... 153* Apponi, Luciano,.......................... 777C Aqeel, Nour,.................... 542B*, 543C* Aquadro, Charles,........................ 439A Aquadro, Charles F., ............ 156, 419B Arama, Eli, .................................. 274A* Arbeitman, Michelle, .................... 582C Arenson, Patricia K.,................... 475A* Argue, Kathryn J.,....................... 587B* Arguello, J. Roman, .................... 451A* Armstrong, Jennifer A.,............... 358A* Arnau, Vicente, ............................ 479B Arora, Gurpreet K., ...................... 190A Artavanis-Tsakonas, Spyros,......... 91*, 413B, 816C Arumeni, Fortuna O., ................... 391A Arziman, Zeynep,......................... 212B Asghari, Parisa, ..............................112 Assaker, Gloria, ........................... 201C Astigarraga, Sergio, ....................654C* Atikukke, Govindaraja,................. 522C Atkins, Mardelle R., .................... 667A* Atkinson, Peter W., ...................... 436A Austgen, MacKenzie,................... 257B Avanesian, Agnesa Avanesian, ... 702C Avila, Frank W., ........................... 443B* Avrani, Shira, .............................. 166A* Axelrod, Jeffrey D., ...................... 375C Ayala-Camargo, Aidee,................ 656B Ayukawa, Rie,.................... 264C, 269B Azad, Priti, ...................................... 93*

B Bach, Erika, ................................. 286A Bach, Erika A.,..................283A, 656B* Bache-Wiig, Sarah Elizabeth,...... 236B Bachtrog, Doris,.............................. 36* Badenhorst, Paul W., .................. 359B* Badrinath, Krishan,...........236B, 502A* Bae, Gina,.................................... 690C Baehrecke, Eric H.,...................Plenary Session I*, 222C, 261C Bailin, Samuel S., ........................ 444C Bainton, Roland J., ...................... 362B Baker, Bruce, ..................................141 Baker, Keith D., .................................20 Baker, Nicholas E., ...........................44 Baker, Phillip W.,.......................... 718A Bakhrat, Anna,............................. 160A Bakhrat, Anya, ................. 246C*, 792C Bakhtojarov, George N., .............. 448A Baksh, Vimala,............................ 722B* Bambina, Shelly, .......................... 564C Bando, Tetsuya, ................. 426C, 674B

Banerjee, Soumya, ..................... 628A* Banerjee, Utpal,................. 219C, 512B Bao, Riyue, ................................. 418A* Baranski, Thomas J., ........................95 Barbash, Daniel, ................ 334A, 434B Barbash, Daniel A.,............ 291C, 419B Bardet, Anaïs Flore,..................... 743B Bardin, Allison,............................. 805A Bar-Dubin, Dikla, ......................... 168C Barnes, Phillip T., ............... 475A, 605B Barolo, Scott, ................................ 109* Baron, Miriam, ............................. 567C Barrio, Rosa,......................693C, 768C Barrios, Natalia, ........................... 731B Barry, Rachael, ............................ 730A Bartoletti, Mathieu, ............ 267C, 535A Bashirullah, Arash, ............ 270C, 271A Bassuk, Alex,............................... 375C Bastide, Héloïse, ............................ 35* Bates, Karen E., .........................612C* Batiha, Osamah,......................... 245B* Batterham, Phil, ................. 589A, 643A Batterham, Philip, ........................ 590B Bauer, Johannes,......................... 382A Bauer, Johannes H., ...................690C* Bauer, Reinhard,............................. 21* Baum, Jayson, ............................. 824B Bauman, Kenny,........................... 613A Baxley, Ryan M.,.........................516C* Baxter, Ellen, ....................................48 Bayat, Vafa,............ 386B*, 405C, 407B Baylies, Mary, ..............69, 169A, 510C Baylies, Mary K.,......505A, 509B, 720C Baynes, Cayla,............................. 378C Bayraktar, Jennifer, ...........................29 Bazinet, Christopher, ... 47, 543C, 547A Beatty, Cathy,............................... 576C Beaty, Cathy,................................ 574A Beauchamp, Jessica M., ............ 517A* Beaucher, Michelle, ..................... 314B Beaucher, Michelle L., ................351C* Bebyakina, Darya S., ................... 332B Beck, D., .........................................144 Becker, Matt,................................ 536B Beckerle, Mary, ............................ 171C Beckerle, Mary C., ............... 114, 170B Beckett, Karen, ...........................240C* Beckingham, Kathleen M.,.......... 580A* Beckingham, K. M.,...........................70 Becnel, Jaime T., ........................ 581B* Bedford, Trevor,............................ 438C Begun, David J., .......................... 437B Beisel, Christian,.......................... 354C Beitel, Greg J.,........221B, 486C, 492C, 493A Bejsovec, Amy, ................................. 4* Bell, Graeme,............................... 383B Bell, John B., ............................... 218B Bellen, H., .........................................76

82

SPEAKER AND AUTHOR INDEX

Bellen, Hugo, .......................... Opening General Session, 39, 386B, 405C, 407B, 806B Bellen, Hugo J., ..................... 75, 818B Bellosta, Paola,........282C, 722B, 727A Belote, John,................................ 546C Benchabane, Hassina, .....242B*, 244A Benhra, Najate,................................. 3* Bennett, Joan, ............................. 393C Benromano, Tali, .......................... 400A Ben-Shahar, Yehuda, ......... 585C, 610A Benson, Jennifer L.,..................... 838A Bento, Ines,................................. 518B* Beppu, Kengo, ................... 264C, 269B Berg, Celeste,.............................. 528C Berg, Celeste A., ......................... 384C Bergland, Alan O., ...................... 464B* Bergman, Casey, ..............................10 Bergman, Casey M.,......... 452B, 735C, 808A* Bergmann, Andreas,............ 84*, 181A, 272B, 275B, 276C, 279C Bergstralh, Daniel T., .................. 296B* Berkaeva, Maria B., .................... 347B* Bernardo, Travis J., .....................714C* Berndt, Anthony J. E.,................. 635B* Berry, Bassam, .................................88 Berryman, M.,............................. 167B* Besansky, Nora,................................15 Betran, Esther,............................ 431B* Betrán, Esther,....................... 34, 433A Bettencourt-Dias, Mónica, ........... 518B Beutler, Bruce, ............................. 562A Bhambhani, Chandan,................243C* Bhan, Veer, ..................... 465C*, 466A* Bhatt, Parag,................................ 646A Bhattacharya, Abhishek,................. 44* Bhawna, K., ................................. 711C Bickel, Sharon E., .............................85 Bickle, Peter,................................ 729C Bidwai, Ashok, ...................636C, 645C Bienstock, Rachelle, .................... 352A Bier, Ethan, .................... 97, 117, 685A Biersmith, Bridget, ............. 521B, 613A Biggin, Mark, ....................................14 Bild, Nicholas A., ......................... 806B Bild, Nick,..................................... 740B Bilioni, Aphrodite,........................ 182B* Bina, Samira, .............................. 193A* Birchler, James, ................. 480C, 769A Birge, Raymond, .......................... 395B Bishop, Clifton, ..................636C, 645C Bitan, Amir, ............ 160A, 166A, 168C* Bittig, Thomas,................................106 Bjorum, Sonia,............................. 580A Blatti, Charles, ................................122 Bloch Qazi, Margaret,.................. 443B Bloyer, Sébastien,........................ 258C Blumenstiel, Justin P.,................. 452B* Boamah, Ernest Kojo,.................216C* Bodmer, Rolf,....................... 117, 562A Boettiger, Alistair N., ............. 54*, 742A Boisclair Lachance, Jean-François,...... 657C* Boley, Nathan, ............................. 729C

Bolival, B., Jr.,...................................70 Bolkan, Bonnie J.,.......................387C* Boll, Werner, ................................ 618C Bolukbasi, Ekin, .............................. 61* Bommireddy Venkata, Venu,......... 137* Bonaccorsi, Silvia, ....................... 289A Boncoraglio, Alessandra,............. 388A Bond, Jeffrey,............................... 425B Bongiorni, Silvia,.......................... 260B Bonini, Christine, ......................... 666C Bonn, Bettina, ............................. 503B* Bono-Lauriol, Sophie, .................. 208A Bonvin Cuddapah, Marianne, ...... 801C Booth, Ben,.................................. 825C Booth, Benjamin, ......................... 729C Borodkin, Vladimir,....................... 205A Borovka, Margarita, ..................... 705C Bosch, Justin, .............................. 280A Bose, Anasua, ................. 636C*, 645C Bossuyt, Wouter,............................. 65* Botchan, Michael, ........................ 292A Bothe, Ingo, ................................ 169A* Botta, Amy M., ............................ 706A* Bouge, Anne-Laure, ....................... 88* Bougé, Anne-Laure, .......................127 Boukhatmi, Hadi, ......................... 506B Boulanger, Jim,............................ 158B Boulianne, Gabrielle L., ............... 655A Boulton, Adam M., ....................... 838A Bournias-Vardiabasis, Nicole,...... 401B Boutros, Michael,......................... 212B Bradley, Pamela,...............................72 Bradley, Robert,................................14 Bratic, Ana M., ............................762C* Braun, Doug, ............................... 270C Brechbiel, Jillian,.......................... 634A Breiden, Bernadette,.........................21 Bremer, Eric,................................ 751A Bricker, Daniel K., ....................... 703A* Brill, Julie, .................... 29, 285C, 530B Brisson, Becky K., ....................... 554B Bristow, Chris A., ........................ 749B* Bristow, Christopher,.................... 754A Bristow, Steve, ............................. 740B Brittle, Amy L., .................................. 2* Brodie, James C., ........................ 782B Brodsky, Michael H., ..................... 122* Brodu, Véronique,........................ 664A Brody, Thomas,.................. 119*, 617B, 738C, 745A Bronner, Denise N., ..................... 632B Brown, Adam, ...................................78 Brown, Casey,.............................. 740B Brown, Christopher D., ................ 806B Brown, Colin W., ............................. 46* Brown, J. L., ................................ 319A* Brown, Marishka K., ................... 577A* Brown, Stephen, .......................... 196A Broyer, Risa, .......................132, 780C* Brumby, Anthony,................... 96, 367A Brunsting, Jeanette,..................... 388A Bryan, Heather, ........................... 714C Bryant, Julie T., ........................... 833B* Bryantsev, Anton,............. 715A*, 741C Buckley, Martin S., ............................58

Budnik, Vivian, ................................115 Buff, Eugene, ....................................84 Bugga, Lakshmi V., ...................... 358A Burg, M., ...................................... 834C Burg, Martin G., ........................... 600C Burke, Nigel, ................................ 657C Burmeister, Margit, ...................... 409A Burn, Katherine, ...............................67 Burn, Katherine M., ....................519C* Burns, Kevin A., ........................... 421A Bushati, Natascha, ...................... 767B Buszczak, Michael,..............101, 533B, 794B, 798C Buttgereit, Detlev, ........................ 503B Buzalewski, Jarrod,...................... 231C Byungura, Fidele, ........................ 552C

C Cachero, Sebastian, .............. 42, 623B Cadigan, Ken,.............................. 243C Cagan, Ross L.,................................95 Caldwell, Jason C., ....................... 143* Callejo, Ainhoa, ........................... 182B Calrson, Joseph,.......................... 729C Calvi, Brian, ..............Plenary Session I Calvi, Brian R.,.................. 256A, 257B, 277A, 343A Campbell, Shelagh, ..................... 700A Campuzano, Sonsoles,................ 731B Cantin, Greg, ............................... 250A Cao, Weihuan, ............................. 395B Capitolin, Cindy,........................... 565A Capri, Michèle,............................. 316A Carballo, Marco A.,..................... 379A* Carbonetto, Salvatore,................. 308B Cardoso-Moreira, Margarida, .....453C* Carlson, J., .......................................76 Carlson, Joe, ............................... 825C Carlson, John R.,......................... 611B Carlson, Joseph, ......................... 816C Carlson, Joseph W.,............... 75, 818B Carmel, Ido, ................................750C* Carmon, Amber, ......................... 787A* Carmona Aldana, Francisco Javier,...... 679A* Carninci, Piero, ............................ 729C Carra, Serena, ............................ 388A* Carrasco-Rando, Marta, ............504C*, 731B Carreno, Sebastien,..................... 287B Carrigan, Matthew, ...................... 810C Carrington, Lauren B., ......................24 Carr Jr., Thomas J., .................... 788B* Carthew, Richard,........................ 770B Cartwright, Iain L., ......................363C* Carvalho, Bernardo,.................... 544A* Casal, José,........................................2 Casali, Andreu, ...........................684C* Casas-Tinto, Sergio, .................... 408C Casola, Claudio, .........................432C* Castillo, Ashley,............................ 658A Castillo-Davis, Cristian I., ............ 430A Cazemajor, Michel, ...........................35 Celniker, Sue, .............................. 749B

Celniker, Susan, ............... 725B, 729C, 816C, 825C Centre for Environmental Stress and Adaptation Research (CESAR), ................................. 707B Cha, Guang-Ho, .......................... 374B Chalopin, Domitille S., ................ 545B* Chalvet, Fabienne,............. 267C, 535A Chambers, Moria C., .................... 151* Chan, Chih-Chiang, ..........................72 Chan, Gina, ................................. 279C Chan, May T.,............................... 608B Chan, Sze Ham, .......................... 252C Chandramouli Iyer, Srividya,....... 622A* Chandrasekar, Keerthy, .............. 320B* Chandrasekaran, Chitra, ..................34 Chandrasekaran, V., .................... 834C Chandrasekaran, Vidya, .............. 687C Chang, Chengyi,.......................... 690C Chang, Che-Wei, ......................... 183C Chang, Geen-Dong, .................... 570C Chang, Henry,...................................29 Chang, Howard,........................... 413B Chang, Jung Sook, .........................148 Chang, Ling Wen, .......................675C* Chang, Sarah, ............................. 565A Chang, Wei-Ling, ........................183C* Chang, Yu-Yun, ............................ 183C Chanut, Helene,........................... 163A Chao, Anna,........................................4 Chapin, Alex, .............................. 778A* Charbonnier, Enrica,.................... 743B Chari, Sudarshan, .......................... 12* Charng, Wu-lin,............................ 407B Charng, Wu-Lin,........................... 405C Chartier, François J.,................... 158B* Chatterjee, Nabanita,...................... 47* Chatterjee, Sujash, ......................... 74* Chattopadhyay, Abanti,.....................79 Chatuvedi, Dhananjay,................. 794B Chau, Johnnie, ............................. 102* Chau, Kimberly M., ...................... 184A Chechenova, Maria, ................... 733A* Chekunova, Anna I., ................... 448A* Chen, Chung-Hao,....................... 183C Chen, Chun-Hong,....................... 652A Chen, Debbie,.............................. 705C Chen, Dong-Yuan, ....................... 229A Chen, Elizabeth, .........Plenary Session Chen, Fading, .............................. 655A Chen, Guang-Chao, .........217A*, 229A Chen, Jia, .................................... 740B Chen, Jie, .................................... 314B Chen, Jing, .................................. 790A Chen, Li, ..................................... 568A* Chen, Linan E.,........................... 773B* Chen, Michael Y., ........................789C* Chen, Qian, ................................ 194B* Chen, Qingwen,........................... 369C Chen, Rui,........................ 23, 79*, 118, 723C, 814A Chen, X.,...........................................70 Chen, Xi,..................................... 175A* Chen, Xiao,.................................. 816C Chen, Xiao J., .............................. 825C

SPEAKER AND AUTHOR INDEX

83

Chen, Yiyun, ...............................723C* Chen, Zhihong, ...................... 84, 275B Chen, Zhijian ‘James’, ................. 570C Cheney, Clarissa M.,................... 184A* Cheng, Yim Ling, ........................ 481A* Cheng, Yuzhong, ........................321C* Cherbas, Lucy,............................. 729C Cherbas, P., ....................................123 Cherbas, Peter,............................ 729C Cherezov, Roman, ....................... 529A Chernyk, Yaroslava, ..................... 373A Cherry, Sara, .................... 561C, 563B, 564C Cheshire, Alan, .................................51 Chesnokov, Igor N., .................... 253A* Cheung, Lily S., ........................... 666C Cheung, Sylvia, ........................... 490A Cheung, Sylvia T. Y., .................... 489C Chiang, C.-Y. Ason,...................... 793A Chiaro, Joseph A., ......................372C* Chiba, Akira, .....................................81 Chicanne, Gaetan,....................... 287B Chiolo, Irene, ..............................330C* Chiu, Yu-Ting, .............................. 670A Cho, Dong Yeon, .......................... 757A Cho, Julio C., .................................. 19* Cho, Kyoung Sang,...................... 278B Chohan, Kultaran S., .................. 467B* Choi, Gahee, ............................... 278B Choo, Amanda,............................ 369C Chopra, Vivek S., ........................ 734B* Chotigeat, Wilaiwan, .................... 532A Chou, He-Yen, ............................663C* Chou, Tze-Bin,............................. 183C Chow, Clement Y.,.......................468C* Chowdhury, Moin,.............................74 Christensen, Stacey,.................... 813C Christensen, Tim, ................ 140, 815B Christensen, Tim W.,.......... 254B, 336C Christiansen, Audrey,.................. 272B* Christophides, George,.....................15 chromatin group, modENCODE, . 344B Chtarbanova, Stanislava,.... 155*, 562A Chu, Kristy, .................................. 410B Chu, Wei-Chen, .......................... 482B* Chuang, Li-Jin, ............................ 217A Chung, HM, ................................. 834C Chung, Jaehoon, ......................... 394A Chung, Se-Yeon, ............................ 72* Cinnamon, Einat, ..............................55 Cirelli, Chiara, ........... Plenary Session* Clandinin, Thomas,...................... 828C Clark, Andrew, ...................... 37, 439A, 446B, 451A Clark, Andrew G., ........33, 453C, 468C Clark, Denise V., ................ 428B, 706A Clark, Kathleen A., ....................... 114* Clark, Nathaniel L.,....................... 156* Clason, Todd,............................... 832A Cleary, Mike, ............................... 650B* Clough, Emily,............................. 541A* Cockerell, Fiona E., .............. 24, 707B* Cofer, Z.,..................................... 763A* Cohen, Robert, ............................ 784A Cohen, Stephen,.......................... 767B

Colella, Alex,................................ 369C Collier, Simon, ................. 159C*, 180C Collins, Frank,...................................15 Colmenares, Serafin U., .............. 330C Comeron, Josep M., ........ 444C*, 478A Conley, Dalton, ............................ 282C Consortium, ModENCODE,......... 812B Cook, Kevin, ....................... 78*, 813C* Cook, Kim, ............................. 78, 813C Cook, Orna, ................................ 685A* Cook, Stacey,............................... 410B Cook, Tiffany, ............................... 747C Cooley, Lynn, ............................Plenary Session I*, 27, 67, 514A, 519C Coolon, Joe D., .................................13 Coppee, Jean-Yves, .........................88 Corbett, Anita,.............................. 777C Corcoran, David,.........................10, 82 Cortier, Elisabeth, ........................ 633C Costa, Luciano da F.,................... 680B Cotton, Sean L.,........................... 192C Couble, Pierre,............................. 316A Coughtrey-Davenport, Dylan, ...... 548B Coulibaly, Mamadou, ........................15 Courey, Albert,..................................55 Cox, Chris,................................... 159C Cox, Daniel N., ............ 41, 622A, 625A Cox, Rachel T., ........................... 520A* Coyne, Jerry A.,........................... 477C Crawford, Justin,.......................... 231C Crest, Justin M.,.......................... 284B* Crews, Stephen, .......................... 630C Crews, Stephen T., ...........................43 Crim, Kathryn, ............................. 159C Cripps, Richard,................ 677B, 715A, 733A Cripps, Richard M.,........... 718A, 741C, 746B Crocker, Justin, .................................11 Crosby, Kate, ............................... 824B Cross, Richard W.,....................... 604A Crozatier, Michèle,....................... 558C Crozatier, Michele,....................... 506B Cruz-Moreno, Beatriz, ......................97 Cryderman, Diane E.,.................. 338B Cui, Jun, ............................... 50*, 551B Cullen, Kristen, ............................ 824B Cumenal, Delphine, ..................... 535A Curtiss, J.,.................................... 157A Cushman, Hannah J.,.................. 744C Cyprys, Anya, .............................285C*

D Daborn, Phil,................................ 589A Dahmann, Christian,............... 68*, 106 Dai, Jing,.....................................546C* Daines, Bryce, ..................723C, 814A* Dalton, Justin,.............................582C* Damm, Vanessa T.,...................... 520A Daneshvar, Kaveh, ..................... 764B* Daniel, John,................................ 404B Danies, Bryce, ..................................79 Dankert, Heiko,...............................148 Dantoft, Widad,........................... 572B*

84

SPEAKER AND AUTHOR INDEX

Dao, Julie,.................................... 832A Dao, Julie C., .............................. 716B* Daum, Gabor, .............................. 503B Davis, Gregory, ............................ 420C Davis, Ilan,................................... 782B Davis, Ronald, ............................. 595A Davuluri, Ramana,............................84 Dayan, Sonia, .............................. 369C Deal, Jennifer,...................................78 Deal, Megan, ....................................78 Dearden, Peter K., ....................... 691A de Belle, J. S.,.................................144 de Celis, Jose Felix,..................... 295A de Celis, Jose Félix, ...........................6 Decelle, Barbara,......................... 287B de Cuevas, Margaret, ................. 802A* Deery, W. J.,......................................70 Delaney, Theresa K., .................. 454A* Delmarre, Valérie, ...........................127 DelSignore, Steven,.................... 686B* Demakov, Sergei A., .................... 347B Denef, Natalie, ................... 200B, 215B Deng, Hua, ................................. 218B* Deng, Wu-Min,................... 281B, 662B Deng, Xinxian, ............................. 755B Dennes, André C., ....................... 185B Derek, Dean, ..................................142 Deryusheva, Svetlana,................786C* Deshpande, Girish,...................... 499A Desplan, Claude, ..............................57 de Vanssay, Augustin,................... 127* Dexheimer, Thomas,.................... 220A Dialynas, George,...........................115 DiAngelo, Justin,................ 449B, 788B DiAngelo, Justin R., .................... 695B* Diego E., Diego E., ............399C, 399C DiFilippo, Robert,......................... 714C Diggins, Lenard, .......................... 385A Diggins, Lenard T.,....................... 402C Dimitriadi, Maria, ......................... 413B Dimlich, Doug, ............................. 413B Dimlich, Douglas,..............................91 DiNardo, Stephen, ............. 797B, 804C DiNardo, Steve,.................................99 Ding, Hongmei,.................................29 Ding, Tian, ................................... 272B Dinur, Tama,................................. 499A Dionne, Heather,.......................... 647B Ditzel, Mark,................................. 265A Dobens, Leonard L., ................... 521B* Dobes, Pavel,..................................154 Dobi, Krista C., ........................... 505A* Doggett, Karen, .............................. 96* Doherty, Olugbenga M.,.............. 599B* Dolezal, Adam, .................................18 Domanitskaya, Elena,................. 200B* Domanus, Marc, .......................... 740B Domingues, Celia, ........................ 138* Domingues, Susana, .................. 433A* Doms, Robert W., ........................ 563B Donegan, Paul,............................ 342C Dong, Qunfeng, ........................... 377B Donti, Taraka,............................... 386B Dorer, D., ..................................... 834C Dorr, Meredith,............................. 628A

Dos Santos, Nicolas, ......... 267C, 535A Drechsler, Maik,.......................... 488B* Drocco, Jeff,................................. 249C Dronamraju, Raghuvar, ............... 352A Dronamraju, Raghuvar G., ......... 340A* Drummond-Barbosa, Daniela, .....524B, 800B Dubin Bar, Dikla,......................... 160A* Dubois, Laurence, ...................... 506B* Dubrovskaya, Veronica, ............... 714C Dubrovsky, Edward,..................... 714C Duckworth, April, ......................... 413B Dugan, Laura,.............................. 416B Duman-Scheel, Molly,................. 305B* Duncan, Jennifer,......................... 585C Dunkelberger, B. S.,........................144 Dunleavy, Elaine, ........................ 313A* Dunn, Graham, ............................ 210C Durand, Bénédicte,...................... 633C Durham, Mary F., ........................ 469A* Dushay, Mitchell S., .................... 751A* Dutta, Pranab,.............................. 333C Dutta, Pranabananda, ................. 339C Duttaroy, Atanu, ........................... 710B Dvorkina, Galina, ........................ 364A* Dworkin, Ian,.....................................12

Engel, Gregory,............................ 716B English, Bevin C., ........................ 549C Engström, Ylva,............................ 572B Enomoto, Tatsuro,.............. 264C, 269B Enriquez, Johnatan, .................... 506B Ephrussi, Anne, ................... 131, 783C Epithelial Biology Department, .... 303C Erdinc, Melek,.................................149 Erives, Albert J., ............................. 11* Ernst, Jason,................................ 754A Ervin, Wendi-Jo, .......................... 600C Escala, Wilfredo,.......................... 406A Escobar, Daniel, ......................... 781A* Esnault, Caroline, ....................... 752B* Estevez, Astrid,............................ 543C Estevez, Joshian,......................... 543C Eva, Fast,...........................574A, 576C Evans, Cory, ................................ 512B Evans, Cory J., ...........................219C* Evans, Iwan, ................................ 210C Evans, Janelle, .................................20 Evans-Holm, Martha,................... 818B Ewer, John,................................... 142* Extavour, Cassandra, ........ 511A, 676A

E

Fabian, Lacramioara,........................29 Fabrizio, James,................. 542B, 543C Fagegaltier, Delphine,.......................88 Fairchild, Michael,.............. 198C, 490A Fairchild, Michael J., .......... 489C, 496A Fan, Yujie, .................................... 227B Fan, Yun,.......................... 275B*, 276C Fang, Ming,.................................. 655A Fang, Xiaolan,............................. 197B* Faradji, Floria,.............................258C* Farajian, Reza, ............................ 654C Farfara, Dorit,............................... 400A Farhadifar, Reza, ........................1, 106 Favors, Sheena E., ...................... 549C Fawaz, Bilal, ................................ 382A Fay, Newton, .....................................42 Feldman, Shaina, ........................ 209B Feng, Siqian, .............................. 355A* Feoktistov, Alexander I.,............... 800B Ferannades, Joyce, ..................... 236B Ferguson, Christopher H., .......... 569B* Ferguson, Micheal, ...................... 205A Fernandes, Caroline P., .............. 389B* Fernandes, Isabelle, .................... 163A Fernandes, Joyce, ............. 502A, 628A Fernandez, Harvey, ..................... 480C Fernandez-Funez, Pedro,........... 397A, 408C Fernandez-Valdivia, Rodrigo, ...... 640A Ferrarese, Roberto, ..................... 411C Ferree, Patrick M., ......................291C* Ferrer, Pierre, .............................. 163A Feschotte, Cedric,........................ 431B Fink, Jill L.,........................................95 Finley, Russell L.,........................522C* Finnegan, David J.,..................... 782B* Fischer, J. A., ....................................70 Fischer, Janice,............................ 214A

Eade, Kevin T.,............................ 724A* Earley, Eric J.,............................. 809B* Eastman, Deborah A., ................765C* Eaton, Suzanne, .................................1 Eckardt, Franka, ...............................21 Eddison, Mark, ............................. 146* Edgar, B.,..................................... 157A Edwards, Rebecca, ..................... 358A Eggleston, Elizabeth,................... 709A Eisen, Michael, .................................14 Eisen, Michael B.,.......... 46, 125, 756C Eisman, R., .......................................76 Eisman, R. C.,............................... 123* Eissenberg, Joel C., ................... 185B* Ejsmont, Radoslav, ...................... 823A Ejsmont, Radoslaw K., ............... 827B* Ekström, Jens-Ola, ...................... 556A Elefant, Felice, ........320B, 327C, 329B, 342C, 345C Eleftherianos, Ioannis, ................ 562A* Elgin, Sarah C. R., ............ 328A, 331A, 337A, 344B, 350B Elgin, SCR, .................................834C* Elhanany-Tamir, Hadas, ...................71 Elias, Maria,................................. 171C Elias, Maria C., ........................... 170B* Eliazer, Susan,..................794B, 798C* Ellis, Stephanie,........................... 490A Ellis, Stephanie J., ..............112, 489C* Emerson, J. J., ............................. 453C Emery, Gregory,..........................201C* Emery, Sarah,.............................. 409A Emmert, David,............................ 814A Emoto, Kazuo, ............................. 197B Enderle, Daniel, ..........................354C* Endow, Sharyn, ..........Plenary Session

F

Fischer, Karin, ................................116 Fisher, Bill, ......................... 725B, 749B Fisher, Katie,................................ 193A Fiston-Lavier, Anna-Sophie, ...... 455B*, 810C* FitzGibbon, Thomas M., .............. 538A Fitzpatrick, Marie E.,.................... 385A Flaherty, Maria Sol,...................... 656B Flannery, Kaitlin, .............................115 Flatt, Thomas,...................................18 Flax, Lindsay,............................... 567C Flood, Thomas,............................ 584B Florens, Laurence,................. 53, 315C Flores, Heather A., ..................... 419B* Flybase Consortium, ................... 814A FlyBase Consortium, ................... 821B FlyExpress Consortium, .............. 811A Foos, Marianna,........................... 402C Foos, Marianna O., ...................... 385A Fortini, Mark, ..............Plenary Session Fox, Donald T.,.............................. 139* Fox, Rebecca M.,........................ 241A* Francis, Nicole, ............................ 356B Franco-Cea, Ari, ............... 198C, 489C, 490A*, 496A Frankel, Nicolas, .........................420C* Fraser, Scott E., ................................80 Freeman, Marc R.,....................... 261C Freer, S., .........................................144 Freilich, Sarah,............................. 804C Frendo, Jean-Louis, ..................... 506B Frenkel, Dan, ............................... 400A Friedrich, Markus,........................ 418A Frise, Erwin,......................725B*, 749B Frizzell, Kimberly A.,................... 779B* Frolov, Maxim, ............................306C* Frolov, Maxim, V.,......................... 309C Frydman, Horacio, ....................... 576C Frydman, Horacio M., ................. 574A* Frydman-Marom, Anat,................ 400A Fu, Shengbo, ..............................726C* Fuchs, Alisa, ................................ 743B Fujioka, M., .................................. 763A Fujioka, Miki,................................... 90* Fujita, Yasuyuki, ........................... 281B Fulga, Tudor A., .................. 126*, 413B Fuller, Margaret T.,............... 103, 548B Fuller, M. T., ......................................70 Furuse, Mikio, .............................. 492C Futschik, Andreas,....................... 458B

G Gadel, Sarah, .............................. 350B Galiana-Arnoux, Delphine, .............155 Gall, Joseph,......................781A, 786C Gall, Joseph G.,..............................139 Gallach Caballero, Miguel,............. 34*, 479B* Gallo, Steven M., ......................... 735C Gamberi, Chiara, ........................774C* Gamliel, Amir, .................................117 Gan, Guangming, ........................ 655A Gangaraju, Vamsi, .......................... 87* Ganote, Carrie, ............................ 432C

SPEAKER AND AUTHOR INDEX

85

Gao, Guanjun, ............................ 314B* Gao, Yuan, ........................................82 Garcia, Mayra, ............................ 766A* Garg, Aprajita, .............................. 149* Garringer, Matthew O., ................ 829A Garton, Russell,................................78 Gaspar, Imre,..................................131 Gatti, Maurizio, ........................... 289A* Gaur, Kriti, .................................. 365B* Gause, Larisa N.,......................... 448A Gavis, Elizabeth,.......................... 634A Gavis, Elizabeth R., ........... 624C, 785B Gazit, Ehud,................................. 400A Gebelein, B.,................................ 763A Gebelein, Brian,................ 421A, 637A, 747C Geer, Marcus J., .......................... 237C Geisbrecht, Erika R., .................. 613A* Gelbart, William, .......................... 814A Geng, Cuiyun,............................. 292A* Genissel, Anne, ........................... 464B Gerbi, Susan,..................................124 Gergen, J. Peter,............................. 59* Gerhold, Abigail, ...............................63 Gerlitz, Offer, .............................. 499A* Gerrard, Dave T., ................... 10, 735C Gettings, Melanie,........................ 208A Geyer, Pamela K.,..........49, 115, 323B, 516C, 771C Ghabrial, Amin,...............................113 Ghabrial, Amin S., ....................... 234C Ghorbani, Mohammad,................. 133* Ghosh, Roshni,........................... 547A* Ghosh, Sanjay, ...........................783C* Gibson, Matthew,......................... 500B Gibson, Matthew C., .......... 294C, 301A Gijón, Miguel,............................... 230B Gilbert, M. Melissa,.......... 307A*, 309C Gilchrist, Daniel A., .........................152 Gilliland, William D., .................... 523A* Gindhart, Joseph G., ................... 187A Girgis, Mina, ............................... 727A* Gittis, Aryn,.................................. 227B Gladstein, Natalie, ....................... 753C Glaser, Robert L., ....................... 575B* Gobom, Johan, ............................ 259A Goh, Lihui, .................................. 616A* Gohl, Daryl, ..................... 349A, 828C* Golyandina, Nina E.,.................... 682A Gonda, Rebecca,......................... 712A Gonzalez, Elizabeth A., .............. 554B* Gonzalez, Josefa,........................... 38* González, Josefa,.............. 455B, 810C Gonzalez, Katie, .......................... 720C González-Crespo, Sergio, ........... 732C Gonzalez-Nino, E., ...................... 157A González-Pérez, Esther,.............. 731B Good, Robert,.............................. 459C Goodliffe, Julie, ............................ 764B Gopalakrishnan, Akila,................ 701B* Gorchakov, Andrey,........... 335B, 337A, 344B, 350B Gorczyca, Michael, ...................... 584B Gorfinkiel, Nicole, ........................ 182B Gouge, Catherine A.,.................. 254B*

Govind, Shubha,.......................... 411C Graham, Brett, ............................. 386B Grant, Bruce, ............................... 449B Graveley, Brenton, ....................... 729C Graze, Rita M., ........................... 476B* Green, Delbert A., ...................... 676A* Greenberg, Anthony J.,................... 33* Grenier, Guillaume,...................... 633C Gresser, Amy L.,......................... 637A* Grewal, Savraj, .................................66 Griffith, Leslie,.............................. 412A Grifoni, Daniela,........................... 282C Grossman, Robert, ...................... 740B Grossman, Tamar R.,.................... 117* Groth, Verena, ............................507C* Grusche, Felix A., ....................... 299B* Grzeschik, Nicola A., ................... 311B Guarnieri, Douglas, ........................146 Guerra, Carlos, ............................ 544A Guerrero, David, .......................... 543C Guerrero, Isabel,.......................... 182B Guerrero, Paola A.,..................... 322A* Guertin, Michael J.,.....................717C* Guichard, Annabel E., .................... 97* Guichet, Antoine, ......................... 664A Guild, Gregory M., ....................... 168C Gunashekere, Shirani, ................. 268A Guo, Dongyu, ...................220A*, 233B Guo, Fengli, ................................. 523A Gupta, Ravi,......................................84 Gutzwiller, Lisa M., ..................... 421A* Gygi, Steven, ............................... 816C

H Haase, Erin A., ............................... 23* Hackett, Sean R., .............................33 Hackney, Jennifer,........................ 521B Haddad, Gabriel, ......... 93, 416B, 573C Haddad, Gabriel G., .......... 414C, 415A Haelterman, Nele,.............................75 Hafezi, Yassi, .............................. 280A* Hafler, Brian,................................ 242B Hagerich, Kelley L.,...................... 591C Hahn, Ines, .......................................21 Hahn, Klaus, ................................ 826A Hahn, Matthew,.................... 121, 432C Hahn, Matthew W., ............ 441C, 460A Hain, Daniel, ................................... 60* Haines, Nicola, ........................... 308B* Halachmi, Naomi, ........................ 649A Halder, Georg, ..................................65 Hales, Karen G., ................ 548B, 549C Haley, Benjamin,.......................... 666C Halfon, Marc S., ..........................735C* Hallal, Dana A.,........................... 632B* Hallas, Rebecca J.,...........................24 Hallman, Clayton N.,.................... 474C Halme, Adrian,................................ 63* Haltiwanger, Robert S.,...... 161B, 640A Hama, Chihiro,............................. 583A Hamada-Kawaguchi, Noriko, ...... 799A* Hammonds, Ann,.....725B, 749B, 825C Han, Mira, ..................................... 121* Han, Seung Yeop, ........................ 278B

86

SPEAKER AND AUTHOR INDEX

Hanna, Sheri L., ......................... 563B* Hannan, Frances, ........................ 596B Hannan, Frances L., ................... 409A* Hannon, Gregory, ........................ 561C Haque, Najm S., .......................... 652A Hara, Yusuke,....................264C, 269B* Harden, Nicholas, .............. 175A, 238A Hargarten, Paul, .......................... 404B Hariharan, Iswar, ............. 17, 84, 280A Hariharan, Iswar K.,............... 63, 652A Harrison, Andrew Marc,..............297C* Harrison, D. A., ............................ 195C Harrison, Douglas,....................... 194B Harshman, Lawrence G.,..................33 Hart, Anne, .......................................91 Hart, Craig M., ............................ 736A* Harte, Peter, ......................300C, 357C Hartenstein, Volker,...................... 749B Hartl, Daniel,................................ 447C Hartl, Daniel L.,...................... 13, 438C Hartman, Bridget, ........................ 628A Hartwood, Eve, ............................ 782B Harvey, Kieran, .................. 268A, 302B Harvey, Kieran F.,............... 299B, 311B Hatini, Victor,................................ 686B Hatori, Ryo,.....................................108 Haueter, Clair,.............................. 407B Haueter, Claire,............ 39, 386B, 405C Hawley, K.,................................... 167B Hawley, R. Scott,.......................... 523A Hay, Bruce A.,.............................. 652A Hayashi, Shigeo,.......................... 497B Hayes, Michael, ........................... 697A Hazelett, Dennis, ........................390C* He, Li, ...............................202A*, 826A He, Miaomiao,.............................. 452B He, Yuchun,............................ 75, 818B Heart, Anne C.,............................ 413B Heberlein, Ulrike, ............................146 Heck, Margarete, ..............................61 Heffer, Alison, ............................. 422B* Heifetz, Yael, ...................... 239B, 750C Helenius, Iiro Taneli, ................... 221B* Helfand, Stephen L.,.................... 690C Helman, Aharon,.................... 55, 732C Hempel, Leonie, ................541A, 807C Henderson, Laura,........................ 140* Hendrix, David, ............................ 734B Henikoff, Jorja G., ........................ 346A Henikoff, Steven,.......................... 346A Herboso, Leire, ...........................693C* Herman, Tory, .............................. 211A Hernandez, Jacob, ...................... 181A Herwald, Heiko, ..............................154 Herz, Hans-Martin, ................ 84, 181A Hice, Robert H.,........................... 436A Hiesinger, P. Robin,...................... 191B Hildebrand, Erica, ........................ 765C Hilgers, Valérie,........................... 767B* Hill, Jahda H., .............................222C* Hime, Gary,.................................. 643A Hime, Gary R.,................................103 Hioe, Tanya, ................................. 512B Hipfner, David, ............................. 530B Hirai, Keiichiro,................... 264C, 269B

Hirashima, Tsuyoshi, ................... 232A Hirsch, Sarah,.............................. 839B Hoch, Michael,..................................21 Hoekstra, Luke A., ....................... 471C Hoffmann, Ary A., ........................ 473B Hofmann, Jules,........................... 562A Hogan, Justin,.............................. 159C Hogenesch, John,.............. 695B, 761B Hohl, Amber M.,............... 323B*, 516C Holderbaum, Laura,.................... 830B* Holloway, David M., ..........680B*, 682A Holmbeck, Marissa A.,................696C* Holub, Nataliya, .......................... 373A* Holztman, S., ....................................76 Hong, Eugenie S., ....................... 358A Hong, Seung-Hyun, ....................597C* Hong, Yoon Ki, ............................. 278B Horabin, Jamila I.,.......................753C* Horn, Lucas A.,...........................555C* Horn, Thomas,............................. 212B Hornbeck, Peter,.......................... 824B Hornbruch, Christina, .................. 513C Horner, Michael A.,...................... 759C Horvath, Elizabeth, ...................... 312C Hoskins, R., ......................................76 Hoskins, Roger, .................729C, 825C Hoskins, Roger A.,................. 75, 818B Hossain, Noor, ............................366C* Hou, David,.....................................104 Hou, Julie,.................................... 233B Hou, Steven, ...................................104 Hrizo, Stacy L., ........................... 391A* Hsiao, Kuangfu, ..................................8 Hsiao, Mary,....................... 414C, 416B Hsieh, Tao Shih,........................... 323B Hsiung, Frank, ............................. 179B Hsu, Hwei-Jan, ............................ 800B Hsu, Tun-Chieh, .......................... 392B* Huang, Brenda, ........................... 777C Huang, He, .................................573C* Huang, Hon-Ren,........................570C* Huang, Jianhua, ...............355A, 704B* Huang, Shao-Kuei, .....................609C* Huang, Xiao,.....................................87 Huang, Yaling,...................................40 Huang, Yi-Chun, .......................... 662B Huang, Yu-Ting, ........................... 670A Huang, Zhenxing, .......................651C* Hubb, Alexander, ......................... 531C Hudson, Andrew M., ....................... 27* Huggins, Peter, ...............................129 Hughes, Michael,......................... 695B Hughes, Micheal,......................... 761B Hughes, Sarah C., ....................... 368B Hughes, Stephanie, ..................... 789C Hughes, Timothy R., .................... 775A Huisinga, Kathryn L., .................. 331A* Hultmark, Dan,............................. 556A Humphreys, Gregory B.,............. 176B* Hunter, Chad M., ........................255C* Hursh, Deborah, .......................... 266B Hwang, Helen, ............................ 638B* Hwang, Soojin, ........................... 278B* Hyde, Embriette,.........................600C* Hyrsl, Pavel,....................................154

I Ibañez, Carmen,.......................... 182B Igaki, Tatsushi, ..................................62 Ihry, Robert,..................... 270C*, 271A Iijima, Koichi, ............................... 380B Iijima-Ando, Kanae, .................... 380B* Ikmi, Aissam, ............................... 500B Il-Seo, Young,............................... 776B Ilvarsonn, Anne M.,...................... 185B Imler, Jean-Luc, ................... 155, 562A Inamdar, Arati A.,........................393C* Innabi, Yanell,..................... 542B, 543C Ip, Tony,........................................ 803B Irvine, Ken, .......................... 137, 310A Irvine, Kenneth D., ....................Plenary Session I*, 161B Ishal, Sarah, ................................ 705C Ishi, Haruhiko,.............................. 740B Ishihara, Keisuke, ........................ 232A Ishikawa, Hiroyuki O., ................. 161B* Ishimoto, Hiroshi,............. 594C*, 771C Ishio, Akira, .....................................108 Islam, Fahmida, ........................... 705C Ismat, Afshan,................................. 51* Itho, Masanobu, ........................... 462C Ito, Hiroki, ................................... 583A* Ito, Kei,......................................... 584B Ito, Naoto, .................................... 803B Itoh, Masanobu,.......................... 445A* Ivey, Lauren E.,........................... 548B* Ivory, Adrienne L.,........................ 263B Iwabuchi, Kikuo,........................... 269B Iyer, Eswar P. R.,............................. 41* Iyer, Eswar PR, ............................ 625A Iyer, Srividya C.,..................... 41, 625A Izquierdo, Denisse, ...................... 705C

J Jackson, F. Rob,........................... 579C Jacobs, J. Roger, ......................... 491B Jacobs, Roger,...................366C, 498C Jafari, Mahtab, ...................364A, 702C Jafar-Nejad, Hamed,.................... 640A Jahanshahi, Maryam, .............8*, 312C Jain, Roshan A., .......................... 785B Jaiswal, Manish, ......386B, 405C, 407B Jan, Yuh-Nung, ............................ 197B Jang, Anna C.-C., ........................ 202A Januaqrio, Suelen,....................... 544A Jaramillo, Carmelita, .................... 677B Jaramillo, MaryAnn, ..................... 715A Jarman, Andew,........................... 641B Jarman, Andrew,.......................... 623B Jarman, Andrew P.,......................... 42* Jastrzebowska, Karolina,..................10 Jawaid, Adeel, ................... 405C, 407B Jaynes, James B.,.............................90 Jaynes, J. B.,................................ 763A Jean, Claude Walser,................... 314B Jeffress, Jennifer K., ................... 211A* Jemc, Jennifer C.,....................... 508A* Jennens, Joanna, ........................ 697A Jennens, Joanna M., ..................708C*

Jennet, Arnim, ............................. 647B Jenny, Andreas, ..................................8 Jensen, Kurt, ............................... 408C Jeon, Hyun-Jin,............................ 702C Jepsen, Kristen,..............................117 Ji, Yingbiao, .......................... 83, 791B* Jiang, Jin, .................................... 803B Jiang, Nan, .................................. 736A Jiang, Yuwei, ....................... 118*, 667A Jiménez, Gerardo, .......55, 232A, 732C Jockusch, Elizabeth,...........................9 Johnson, D.,................................. 834C Johnson, Oralee, ......................... 581B Johnson, Robert W., ................... 737B* Johnson, Teri J.,........................... 523A Johnson, Travis K., ............... 24*, 707B Johnson, William,......................... 571A Johnston, Robert J., ....................... 57* Jones, Bradley W., ....................... 737B Jones, CJ,.................................... 834C Jones, Corbin, ............................. 809B Jones, Corbin D., ......................... 437B Jones, D. Leanne, ...........................103 Jones, Gabriel, ............................ 790A Jones, Tiffani A., ............................... 7* Jones, Whitney,...................................4 Joshi, Meghana, .......................... 739A Joyce, Eric, ................................... 136* Juge, Francois, ............................ 227B Jülicher, Frank, ...........................1, 106 Junell, Anna,................................ 572B Junker, Michelle, .......................... 231C Junuthula*, Arunkumar, ............... 569B Jusiak, Barbara,................................23

K Kadaba, Madhura, ....................... 256A Kadlec, L.,.................................... 834C Kadlec, Lisa A.,...........................231C* Kadrmas, Julie,...........................171C* Kadrmas, Julie L.,........................ 170B Kafatos, Fotis,...................................15 Kahali, Bhaskar,.................636C, 645C Kalamarz, Marta. E.,.................... 411C Kalasinsky, Victoria K., ............... 509B* Kalay, Gizem,..............................423C* Kalifa, Yossi,................................. 499A Kalinka, Alex T., .............................. 10* Kallakuri, Sowjanya, ................... 247A* Kamiyama, Daichi,.......................... 81* Kamiyama, Rie, ................................81 Kampinga, Harm, ........................ 388A Kanakousaki, Kiriaki, ..................294C* Kang, Min-Ji,............................... 394A* Kang, Yunsik, ....................270C, 271A* Kanger, Hans,.....................................5 Kango-Singh, Madhuri,......268A, 669C Kankel, Mark,......................... 91, 413B Kanodia, Jitendra S., ....... 186C*, 427A Kanon, Bart, ................................ 388A Kao, Chih-Fei,.................. 621C, 639C* Kapadia, Bhaveen, ...................... 816C Karasov, Talia,.............................32, 38

SPEAKER AND AUTHOR INDEX

87

Karpen, Gary, ............. 86, 313A, 324C, 337A, 344B, 350B Karpen, Gary H., ......................... 330C Karr, Timothy L., .......................... 545B Kaschube, Matthias, .........................25 Kashevsky, Helena, ........................135 Kassis, Judith, ...................319A, 321C Kathuria, Hitesh,...............614B*, 829A Katzfey, Erin,................................ 226A Kaufman, T.,.................................... 76* Kaufman, T. C., ...............................123 Kaufman, Thom, .................... 78, 813C Kawakatsu, Yasuhito, .................. 223A* Kazemian, Majid, ............................122 Kearney, Alison L.,....................... 832A Kee, K., ........................................ 157A Keebaugh, Erin S.,.......................... 16* Keefe, Devin, ............................... 385A Kekis, Mariana,........................... 775A* Kelleher, Erin, ............................. 434B* Kelley, Richard, ............................ 360C Kellis, Manolis,.........740B, 749B, 754A Kelly, Seth,................................... 777C Kennedy, Cameron, ..................... 350B Kern, Andrew, .................................120 Kernan, Maurice, ......................... 609C Kerstin, Hofmeyer, ....................... 654C Kessler, Thomas, ........................ 259A* Khan, Abid, .................................. 764B Khanna, Mansi R., ...................... 820A* Kharazmi, Jasmine, .................... 728B* Kharchenko, Peter, ..................... 337A, 344B, 350B Kheradpour, Pouya, ..........740B, 754A* Khoo, Peytee, ............................. 367A* Kikuchi, Moto, .....................................9 Killip, Lauren E., ............................. 66* Kim, Ae-Kyeong,.......................... 597C Kim, Eugene, ............................... 412A Kim, Jane C., ................................ 135* Kim, Jihan,........................................92 Kim, Leslie, .................................. 831C Kim, Michael, ............................... 626B Kim, Mike,.........................................81 Kim, Min-Young, ......................... 524B* Kim, Sun Woo, ................................156 Kim, Y.,......................................... 178A Kim, Yoosik, .........................56*, 232A* King-Jones, Kirst, ............. 694A, 700A, 701B Kirov, NiKolai, .............................. 726C Kiss, Istvan, ................................. 247A Kitamoto, Toshi, ........................... 594C Kitamoto, Toshihiro, ..................... 771C Kittler, Ralph, ..................................111 Klein, Adam P., ........................... 265A* Klein, Michael W., ........................ 516C Klein, Yifat,................................... 649A Klovstad, Martha, ........................ 248B Knust, Elisabeth,..... Plenary Session I* Kobey, Robert, ............................ 709A* Koenig, Tina,.....................................68 Kofler, Robert,.............................. 458B Koganezawa, Masayuki, .............. 583A Kohl, Kathryn, ............................. 290B*

Kolaczkowski, Bryan,.................... 120* Kolesnikova, Tatiana D.,.............. 332B* Kolodkin, Alex, ..................................92 Komosa, Martin, .......................... 491B Kong, Eric C.,............................... 362B Kong, Nikki, ................................. 734B Kong, Ying, .................................. 755B Konieczko, Kevin,......................... 270C Konikoff, Charlotte, ..................... 811A* Konsolaki, Mary, ......................... 395B* Korenberg, Julie R., ........................117 Kornberg, Thomas B.,.................. 179B Kornhauser, Jon, ......................... 824B Koryakov, Dmitri E., ..................... 332B Kotadia, Shaila, .......................... 293B* Kotova, Elena, ..................................83 Kottgen, Michael,......................... 410B Kou, Jing,..................................... 507C Koya, S. Kiran, ............................ 755B* Kozak, Benjamin M.,.................... 184A Kracklauer, M. P., ............................ 70* Kraft, Robert, ............................... 378C Kraja, Emona,.................................133 Krämer, Helmut,..............................150 Krasny, Michelle,.......................... 656B Krauchunas, Amber R., ..............534C* Kreitman, Martin, ................. 111, 383B Kreitman, Marty, .......................... 681C Kretzschmar, Doris, ..................... 387C Kronhamn, AnnaKarin, ................ 556A Kronhamn, Jesper, ..................... 556A* Kronja, Iva, .................................525C* Krsticevic, Flavia,......................... 544A Ku, Hsueh-Yen,............................ 229A Kuklin, Elena,............................... 412A Kulikov, Alex M.,............... 435C*, 448A Kumar, Justin, .................... 665B, 672C Kumar, Sudhir, ..................... 122, 811A Kumar Kandasamy, Suresh, ........ 189C Kundu, Mukta, ........... 119, 738C, 745A Kundu, Mukta R.,........................ 617B* Kunes, Sam, ................................ 570C Kunitake, Ryan, ........................... 330C Kuntimaddi, Aravinda,.................. 622A Kuo, Dennis, .....................................55 Kuo, Vicky, .................................. 224B* Kuroda, Mitzi,...........337A, 344B, 350B Kussell, Edo,.....................................57 Kuthethur, Guruharsha, ............... 816C Kuzin, Alexander,....... 119, 617B, 745A Kuzin, Alexander B., ...................738C* Kwak, Su-Jin,..................................118 Kwon, Deborah,........................... 321C Kwon, So Hee,............................315C* Kwon, So Yeon,............................ 359B

L LaFave, Matthew C., ................... 251B* LaFever, Leesa M., ..................... 800B* Lahr, Eleanor, .................................142 Lai, Eric,....................................... 831C Lakshmi, Girija,........................... 790A* Lallet, Sylvie, ......................................3 Lam, Geanette,.................................20

88

SPEAKER AND AUTHOR INDEX

Lamblin, Anne-Françoise,............ 275B LaMora, Angie D.,.......................585C* Lan, Lan,..................................... 784A* Landolin, Jane, ................ 729C*, 825C Landsberg, Katharina, ....................106 Lange, Bodo, ............................... 259A Langley, Charles H., .......... 456C, 460A Langley, Jana,............................. 835A* Langley, Sasha A.,......................324C* Lao, Tingjia, ................................ 424A* Lapchenko, Maria, ....................... 342C Laplante, Caroline, ...........................28 Laprise, Patrick, ........................... 158B Larsson, Nils-Goran,.................... 762C Lasko, Paul, ................................. 774C Laskowski, Kate,.......................... 454A Lassmann, Timo, ......................... 729C Latapie, Yvan, .............................. 163A Lattao, Ramona, .......................... 289A Laurencon, Anne, .......................633C* Lawlor, Kynan, ............................396C* Lawniczak, Mara,............................ 15* Lawrence, Peter,.................................2 Layne, Jessica, ............................ 159C Lazebny, Oleg E., ........................ 435C Lazzaro, Brian P.,......................... 461B Leatherman, Judy, .......................... 99* Lebel, Cindy, ................................ 377B Lebestky, Tim J., ........................... 148* Lebo, Matthew, ............................ 582C Le Borgne, Roland,.................. 3, 240C Le Droguen, Pierre-Marie, .......... 664A* Lee, Brian, ................................... 700A Lee, Byung-Sup, .......................... 702C Lee, Grace Y. C., .........................456C* Lee, Ji Inn, .................................. 739A* Lee, Kyu-Sun, ........381C*, 597C, 702C Lee, Mark . J., .............................. 411C Lee, Siu F.,................................... 473B Lee, Tom, ..................................... 275B Lee, Tzumin, ..... 40, 620B, 621C, 639C Lee, Yen-Hsien,............................ 663C Lee, Young-Ha, ............................ 374B Lee, Yuan M., .............................. 629B* Lee, Yuan-Ming, ........................... 482B Lehmacher, Christine,.................. 515B Lehmann, Michael, ...................... 699C Lehmann, Ruth, ........................... 207C Lehrach, Hans, ............................ 259A Lei, Elissa, ................................89, 128 Leips, Jeff, ........................ 454A, 469A, 472A, 555C, 569B Lenkov, Kapa, .............................. 455B Leonard, Caron M.,...................... 206B Leonardi, Jessica,....................... 640A* Leroy, Jacqueline, .............. 267C, 535A Lesperance, Marci M., ................. 409A Letizia, Analisa, ........................... 731B Letsou, Anthea, ........................... 176B Leung, Albert C.,......................... 368B* Leung, W.,.................................... 834C Leung, Wilson,............................. 328A Levine, Michael,........... 54, 734B, 742A Levis, Robert W., ........................ 818B* Levy-Sakin, Michal, ..................... 400A

Lewis, Peter, ................................ 292A Li, Caroline R.,............................ 233B* Li, Huabing, ................................. 350B Li, Jinghong, ................................ 365B Li, Ling, .............................................66 Li, Renhua, ...................... 541A, 807C* Li, Sheng, .................................... 704B Li, Wei,..............................248B*, 814A Li, Wei-Hao, ................................ 203B* Li, Weizhe, .................................. 410B* Li, Willis,.............................. 100, 333C, 339C, 365B Li, Xiao,........................................ 773B Li, Xiao-Yong, ...................................14 Li, Xiazhen,.................................. 546C Li, Xingguo,.................................. 771C Li, Yi-Dong, .................................. 640A Li, Yumei, ..................... 79, 723C, 814A Li, Yun, .......................................... 101* Li, Zhe,..............................................79 Li, Zhihong,.................................. 386B Li, Zhihuan,.................................225C* Li, Zirong,..................................... 740B Liang, Hsiao-Lan, .............726C, 730A* Liang, Suh-Yuen, ......................... 229A Liao, Aaron, ................................. 516C Liberman, Louisa M.,................... 660C Liebl, Eric C., ..............................237C* Lightcap, Samantha B., ..............549C* Li-Kroeger, David,........................ 637A Lim, Chiat Koo, ...........................360C* Lim, Su Jun,..................... 333C*, 339C Lin, Chia-Hui,.............................. 341B* Lin, Guonan, ................................... 98* Lin, Haifan, .......................................87 Lin, Nianwei, ...............................348C* Lin, Shengyin,.............................. 784A Lin, Shih-Han,.............................. 670A Lin, Shuping,................................ 616A Lin, Suewei, .................................... 40* Lin, Yong, ..................................... 407B Lin, Yong-Qi, ................................ 405C Linder-Basso, Daniela, ............... 337A, 344B, 350B Linheiro, Raquel, ......................... 808A Lipatov, Mikhail, ........................... 455B Lipp, Hans Peter, ......................... 728B Lipshitz, Howard, ......................... 773B Lipshitz, Howard D.,..................... 775A Lipsick, Joe,................................. 721A Lipsick, Joseph, ................. 288C, 292A Lis, John T.,............................ 58, 717C Liu, Che Hsiung, .............................146 Liu, Cindy (Ze), ............................ 613A Liu, Dongmei, .............................. 522C Liu, Hsiu-Yu, ................................ 312C Liu, Ji-Long, ................................. 772A Liu, Luping, .................................. 830B Liu, Raymond, ..................................30 Llopart, Ana, ................................ 478A Lloyd, Thomas E.,........................... 92* Lockton, Steven, ...............................36 Logan, Mary,................................ 261C Long, Anthony,............................. 364A Long, Manyuan,................. 453C, 545B

Loof, Torsten, ..................................154 Lopatto, D., .................................. 834C Lopes, Francisco JP,.................... 680B Lopes, Hedibert F., ...................... 545B Lopez, A. Javier, .................. 129, 789C Lopitz-Otsoa, Fernando, .............. 768C Loppin, Benjamin,........................ 316A Lora, Carlina, ..................... 282C, 727A Lott, Susan, ................................. 681C Lott, Susan E., ............................756C* Louie, Alex, .....................................151 Lovato, Tyanna,............................ 741C Lovato, TyAnna, ........................... 733A Lovato, TyAnna L., ...................... 718A* Loya, Carlos M., .............................126 Lu, Beika,.................................... 610A* Lu, Bingwei, ................................. 653B Lu, Cecilia S., .................................126 Lu, Hui Qi,.................................... 188B Lu, Jian, .......................................... 37* Lu, Qiuheng, ...............................162C* Lu, Xuemin, ................................249C* Lu-Bo, Ying, ................................. 573C Lucas, Bethany G., ...................... 484A Ludwig, Michael,................ 383B, 806B Ludwig, Michael Z.,....................... 111* Luengo Hendriks, Cris, ................ 681C Lund, Emily, ................................. 385A Lund, Emily A., ............................ 402C Luo, Hua, ..................................... 775A Lusk, Richard W.,.......................... 125* Lynch, Brian T., ............................ 237C Lyons, Amanda C., ............ 836B, 838A Lyons, Ana M.,............................. 438C Lytle, Stacey,............................... 449B*

M Ma, Lina,............................... 42, 623B* Macdonald, Stuart J.,................... 470B Macgregor, Anne, ........................ 566B MacIntyre, Ross,.......................... 787A Mackay, Trudy, ................... 603C, 607A Mackay, Trudy F. C., ........... 467B, 601A MacMullin, Allison,....................... 498C Madden, Laurence,...........................84 Maeda, Reo, ........................ 108, 223A Maeng, Oky,................................ 374B* Maggert, Keith, ........318C, 322A, 325A Maggert, Keith A.,........................ 317B Maguire, Kiley, ............................. 189C Mahapatra, Cecon T., ................. 425B* Maheshwari, Shamoni, ............... 334A* Mahmood, Tanya F.,.................... 491B* Mahoney, Matt B.,..............385A, 402C Mahowald, Anthony, .................... 548B Main, Bradley J., .......................... 476B Maines, Jean, .................................101 Majumdar, Amitabha,.................... 145* Maksymiv, Daria, ......................... 373A Malone, John H., ........................ 757A* Manak, J. Robert, .......................375C* Manansala, Miguel, ..................... 650B Mandilaras, Konstantinos, .......... 578B* Mangrola, Devna, ........................ 358A

Maniatis, Tom,.............................. 570C Manning, Lathiena A.,.................204C* Manu, Manu,........................ 111, 683B Marchand, Virginie,...................... 783C Marchetti, Sarah, ......................... 350B Mardon, Graeme, .......... 23, 118, 667A Marenda, Daniel R.,.................... 376A* Marín, Ignacio,............................. 479B Mariño, Karina, ............................ 205A Mariyappa, Daniel N., ................. 205A* Mark, Edward, ............................. 393C Markstein, Michele,...............19, 831C* Markus, Friedrich,........................ 429C Marmion, Rob, ............................177C* Marquez, Jhomar E., ................... 277A Martin, Adam C.,............................. 25* Martin, Alicia R., .........................384C* Martín, Mercedes, ..............................6 Martin, Paul, ................................ 210C Martin-Blanco, Enrique, ......................5 Martinez, Melody M., ................... 718A Martin-Peña, Alfonso, ................. 595A* Marts, Sherry, ......................... Opening General Session Maruyama, Rika, ........................483C* Marygold, Steven,........................ 821B Mason, Grace A.,......................... 746B Mason, James M., ...................... 340A, 352A*, 353B Mason-Suares, Heather,.............300C* Masurekar, Prakash,.................... 393C Mathew, Dennis, .......................... 611B Matova, Nina M., ........................ 557B* Matsui, Maiko,.............................. 552C Matsumoto, Ken,.......................... 583A Matsuno, Kenji, .................... 108, 223A Matthys, Erin,............................... 708C Mattox, William, ........................... 586A Matunis, Erika,............................. 802A Matute, Daniel R.,.......................477C* Mayer, Nasima,............................ 362B Mayor, Federico, .................................6 Mazanowski, Emily, ....................342C* McAllister, Bryant F., .................... 771C McCall, Kim, ............................52, 134, 246C, 262A, 265A, 273C, 532A McConnell, Gretchen H., ............ 538A* McConnell, Kristopher H.,........... 343A* McCormack, Ryan, ...................... 713B McCutchan, Michael, ......................122 Mc. Gillivray, Shauna, .......................97 McGraw, Molly M., ...................... 484A* McIntyre, Lauren M.,.................... 476B McKearin, Dennis, ..........................101 McKechnie, Stephen W.,........ 24, 707B McKeon, Meghan, ....................... 753C McKim, Kim, ...................................136 McKim, Kim S., .................. 297C, 298A McLeod, Catherine, ..................... 396C McMillan, Emily A., .....................234C* McNeil, Casey L., ....................... 470B* McNeil, G.,................................... 834C McNeill, Helen, .................... 107, 678C McPhee, Christina K.,.................261C* McQuilton, Peter, ........................ 821B*

SPEAKER AND AUTHOR INDEX

89

McVey, Mitch,..............................252C* McWhorter, Amy, ......................... 219C Mechler, Bernard, ........................ 247A Mediatore, James, ....................... 402C Mediatore, Jim, ........................... 385A* Medvedeva, Anna,....................... 417C Megley, Colleen, .......................... 765C Mehra, Shweta, ........................... 393C Mehrotra, Sonam,.............. 256A, 277A Meier, Pascal, .............................. 265A Meiklejohn, Colin, ........................ 696C Meiklejohn, Colin D.,....................... 13* Meisel, Richard,.......................... 446B* Melicharek, David, ....................... 376A Meller, Victoria, .................. 755B, 758B Meng, Tzu-Ching, ........................ 229A Menon, Debashish,..................... 758B* Merdes, Gunter,........................... 212B Merzetti, Eric M.,......................... 719B* Messer, Philipp, ..........................32, 38 Metzger, Thomas, ........................... 69* Metzger, Thomas J., .................... 509B Metzstein, Mark M., ................ 7, 487A, 778A, 779B Meyer, Emily, ............................... 500B Meyer, Emily J., .......................... 301A* Meyer, Régis,............................... 316A Mezuman, Sharon, ...........................55 Michelson, Andrew, ..................... 688A Middha, S., .....................................123 Miles, Cecelia M., .......................681C* Millard, Tom, ................................ 210C Millburn, Gillian, ........................... 821B Miller, Adam,................................ 211A Miller, D.,...........................................76 Miller, Justine,.............................. 605B Miller, Steve, ................................ 740B Milner, Martin,.............................. 210C Milo, Marta,.................................. 193A Milton, Claire,.............................. 302B* Min, Kyung-Jin, ...........................702C* Min, Sarah, .................................. 650B Minakhina, Svetlana, ......... 304A, 560B Minocha, Shilpi, ..........................618C* Minoda, Aki,................................. 330C Minoda, Akiko, .................337A, 344B*, 350B Mintseris, Julian,.......................... 816C Mishra, Monalisa, ....................... 377B* Mislak, Andrea,............................ 273C Misra, Jyoti R.,............................759C* Missirlis, Fanis, ............................ 578B Mistry, Hemlata,........................... 372C Mitchell, Jude,............................. 589A* Mito, Taro, ........................ 426C*, 674B Mitrofanov, Vladimir G.,...... 440B, 448A Miyatake, Kazushi,....................... 445A Miyawaki, Atsushi, ............................62 Moberg, Kenneth, ........................ 777C Moberg, Kenneth, H., .................. 309C Moberg, Kenneth H., ............. 64, 307A Modi, Rohan M., ......................... 397A* Moffat, Kevin, ..................................146 Moghimi, Mona, ........................... 824B Moline, Christopher S., ............... 206B*

Mollica, Emanuela, ...................... 182B Molnar, Cristina, ............................... 6* Molnar, David,.............................822C* Monfort-Prieto, Elena,.......... 132, 780C Monier, Solange,.......................... 240C Monroe, Kate, .............................. 176B Montague, Shelby A., ................. 611B* Montchamp-Moreau, Catherine,.......35 Monteiro, Antonia, .... Plenary Session* Montell, Craig, .......... Plenary Session* Montell, Denise,................. 202A, 826A Montooth, Kristi, .......................... 709A Montooth, Kristi L., .......... 471C*, 696C Monzo, Kate,................................ 250A Moore, Edwin D. W.,........................112 Moore, Sarah R., ......................... 430A Morais-de-Sá, Eurico,..................... 31* Morawe, Tobias,.............................. 26* Morciano, Patrizia, ....................... 314B Moreira, Severina, ....................... 210C Morgan, Sarah M.,...................... 691A* Morin-Poulard, Ismael, ................ 558C Morley, Samantha,....................... 697A Morris, James, ............................. 323B Morris, Robert,............................. 449B Morris, Siti Nur Sarah, ..... 382A*, 690C Morriso, Carolyn, ......................... 740B Morrison, Carolyn A.,................... 806B Morriss, Ginny,............................ 677B* Morton, David, ...................390C, 606C Moshkovich, Nellie,....................... 128* Motiwale, Mansi,.......................... 433A Moyer, Katherine,......................... 491B Mueller, Arno, ...................................60 Mukherjee, Ashim,....................... 413B Müller, Arno, ................................ 205A Müller, Martin,............................. 349A* Muñiz Ortiz, Jorge, ...................... 363C Murphy, Chris,.............................. 647B Murphy, Maura,............................ 364A Murphy, Robert, ........................... 230B Mushegian, Arcady, ..........................53 Muskavitch, Marc,.............................15 Myat, Monn Monn,................. 73, 495C

N Nag, Sanjay, ............................... 710B* Nagengast, A.,............................. 834C Nagengast, Alexis,...449B, 692B, 788B Naidoo, Nirinjini, .......................... 577A Nainaparampil, Jaison J., ............ 397A Nakagoshi, Hideki,................. 57, 659B Nakamoto, Maggie,.....................564C* Nakamura, Mitsutoshi,....................108 Nakamura, Taro, ................ 426C, 674B Nakazawa, Naotaka, .......... 108*, 223A Nam, Sang-Chul, ........................ 668B* Namdar, Yuval,............................. 274A Namolovan, Liliana, ....................819C* Nanogi, Lulu, ............................... 727A Nardozzi, Shannon, ........... 542B, 543C Narzinski, Kirk,..................................95 Nash, Howard,............................. 220A Nash, Howard A., .............. 591C, 592A

90

SPEAKER AND AUTHOR INDEX

Nashchekin, Dmitry,.................... 172A* Neafsey, Dan, ...................................15 Neckameyer, Wendi,.................... 587B Neckameyer, Wendi S., .............. 646A* Negre, Nicolas, ........................... 740B* Nègre, Nicolas, ............................ 806B Nelson, Cloyce E., ......................741C* Nelson, Kevin S., ............ 492C*, 493A* Nern, Aljoscha, ........................... 647B* Newfeld, Stuart, .............. 631A*, 658A* Newton, Fay, ............................... 641B* Ng, Shui-Ying, ............................579C* Ngo, Teri, ..................................... 647B Nguyen, Kerrie,............................ 242B Nguyen, Nina,.............................. 685A Nguyen, Son C., ......................... 356B* Ni, Jian-qian,................................ 830B Ni, Ting, ............................................82 Nibu, Yutaka,................................ 720C Nichols, Charles, ......................... 581B Nicholson, Sarah C.,...................309C* Nickel, Sarah, .............................. 705C Nicolay, Brandon,......................... 306C Nicolay, Brandon, N., ................... 309C Nien, Chung-Yi, ........................... 726C Niepielko, Matthew G.,................ 427A* Nieva, Claudia, ............................ 732C Nikitina, Ekatherina,....................417C* Nilson, Laura, .............................. 657C Nilson, Laura A., ............................. 28* Nirit, Matia, .................................. 649A Nisha, Parul, ................................... 89* Nizami, Zehra, ............................. 786C Nizet, Victor,........................... 97, 415A Noji, Sumihare, .................426C, 674B* Nolan, N. W. C.,...............................144 Noll, Markus,................................ 618C Nolte, Viola, ................................. 458B Nordhoff, Eckhard,....................... 259A Nore, Beston F., ........................... 799A Norvell, Amanda, ........................ 776B* Noselli, Stéphane, ....................... 208A Nowak, Scott J.,..........................720C* Nuzhdin, Sergey, ......................... 464B Nuzhdin, Sergey V., ..................... 476B

Ohyama, Tomoko, .............................39 Oke, Ashwini,............................... 377B O’Keefe, D.,.................................. 157A O‘Keefe, Louise, .......................... 396C O‘Keefe, Louise V., .....................369C* Okegbe, Tishina C., ....................804C* Okumura, Takashi,..........................108 Okumura, Takasi Okumura, ......... 223A Okunade, Adewole L., ......................95 Olesnicky, Eugenia C.,................624C* Oliver, Brian, ..................... 541A, 757A, 807C, 812B O’Neil, Phil,.................................. 402C O’Neil, Phil,.................................. 385A O’Neill, Ryan S., ......................... 428B* Önel, Susanne-Filiz, .................... 507C Ong, SengKai, ............................ 526A* Onorato, Thomas M., .................. 550A* Orenic, Teresa, ............................ 739A Orenic, Teresa V.,......................... 673A Oros, Sarah M., ..........................642C* Orozco, Pablo, ............................. 458B Orr-Weaver, Terry,........................ 525C Orr-Weaver, Terry L., ......................135 Orsi, Guillermo A., ...................... 316A* Oshiaki, Yoshiaki,..............................57 Ospina, Jason,............................. 688A Osterfield, Miriam, ...................... 527B* Ostrovsky, Lilly, ............................ 412A Ote, Manabu,............................... 583A Ou, Qiuxiang,.............................. 694A* Overton, Lewis J.,........................ 251B Oyallon, Justine, .......................... 558C Ozaki, Ayumi, .................................108

O Obar, Robert,..............................816C* O’Brien, Peter, ................... 409A, 596B O’Brochta, David, ........................ 752B O’Brochta, David A., ................... 436A* O’Connor, M., .............................. 178A Ocorr, Karen, ....................... 117, 562A O’Day, Diana,.............................. 586A* Odenwald, Ward, ......................... 738C Odenwald, Ward F., ... 119, 617B, 745A O’Donnell, Janis, ......................... 599B Ogereau, David, ...............................35 Oh, Hyangyee,............................ 310A* O’Hara, Katie, ...................................92 Ohler, Uwe,..................................... 82* Öhler, Uwe,.......................................10 Ohsawa, Shizue,............................. 62* Ohuchi, Hideyo, ................. 426C, 674B

P Pack, Allan I.,............................... 608B Paddibhatla, Indira,.....................411C* Paetkau, DW, ............................... 834C Page-McCaw, Andrea,................. 209B Pai, Lei-Mei,................................. 203B Pai, Li-Mei,................................... 663C Pak, Changhui, ...........................777C* Palanker Musselman, Laura, .......... 95* Palladino, Michael J., ................... 391A Palmer, Ruth,............................... 235A Palozola, Katie C., ....................... 237C Pan, Duojia (DJ) .......Plenary Session I Pan, Hongling, ..................................75 Panaram, Kanchana, ....... 574A, 576C* Pantoja, Mario,.............................. 116* Papapetropoulos, Spyridon, ........ 406A Papasaikas, Panagiotis,......129*, 789C Papoulas, Ophelia, ..................... 250A* Paquette, Nicholas,...................... 568A Paredes, Silvana,........................ 325A* Paris, Mathilde, ............................... 14* Parisi, Federica,..........................282C* Park, Danny, .....................................15 Park, Maiyon,............................... 180C Park, Peter, ..............337A, 344B, 350B Park, Soo, .................................... 825C Park, Soo-Young,........................ 383B* Park, Sung-Yeon,........................ 266B*

Parkash, R.,................................. 711C Parker, David S.,.............................109 Parkhurst, Susan M., ........................30 Paro, Renato,..................... 212B, 354C Paroush, Ze’ev,............................ 232A Paroush, Ze’ev,.....................55*, 732C Parrish, S., ................................... 834C Parrish, Susan, ........833B, 835A, 839B Parsa, Bayan, .............................. 816C Parsons, Linda M.,....................... 311B Partridge, Linda, .......................... 762C Pass, Günther, ............................. 515B Pastor-Pareja, José, .................... 371B Pastor-Pareja, Jose C.,............... 494B* Patel, Meghna V.,......................... 632B Patel, Unisha B., .........................495C* Patel, Vishal K., ..........................273C* Patterson, Bruce W.,.........................95 Paulson, Ariel, ............................. 341B Paululat, Achim,................. 488B, 515B Payrastre, Bernard,...................... 287B Payre, François, ................. 287B, 420C Payre, Francois, ........................... 163A Peabody, Nathan, .......................588C* Pearce, Elspeth, .............. 226A*, 501C Pearson, Joseph,........................630C* Pearson, Neil J., .........................303C* Pei, Shanshan, ............................ 194B Peled, Sivan,................................ 400A Peluso, C., .................................. 178A* Peng, Cheng,............................... 704B Peng, Hanchuan, ............................ 45* Pennetier, Delphine, ...................558C* Perdigoto, Carolina N., ............... 805A* Pereira, Andrea M.,........................... 5* Peretz, Gabriella,........................792C* Perez, Coralia, ............................. 768C Pérez, Coralia,............................. 693C Perkins, Alexander,...................... 198C Perkins, Alexander D., .................. 112* Perkins, Lizabeth, ........................ 830B Perlich, Justin, ............................. 604A Perona, Pietro,................................148 Peronnet, Frédérique,........ 258C, 535A Perrimon, Norbert, ...................19, 153, 485B, 824B, 830B, 831C Perry, D. W., ................................195C* Perry, Michael, ..................................54 Perry, Michael W., ....................... 742A* Perry, Trent,.......................589A, 590B* Peters, Nathaniel, .......................528C* Petersen, Andrew, ...................... 398B* Peterson, Jeanne,........................ 273C Peterson, Jeanne S., .................. 262A* Peterson, Kirk L., ............................117 Petrie, Alison,............................... 245B Petrov, Dmitri, ........................ 38, 810C Petrov, Dmitri A.,................... 32*, 455B Pfeiffer, Barret,............................. 647B Pfleger, Cathie, ........................ 8, 312C Pham, Binh, ................................. 401B Pham, Linh N.,.............................. 152* Phelps, M.,........................................76 Piazza, Nicole M.,....................... 697A*

Pick, Leslie, ...............Opening General Session, 233B, 422B Pilitt, Kristina,..................... 436A, 752B Pines, Mary,.......................198C, 489C Pines, Mary K., ........................... 496A* Pinnola, Aaron, .................................83 Pinto, Belinda S., ............................ 49* Pirraglia, Carolyn M., ...................... 73* Pirrotta, Vincenzo,............. 337A, 344B, 350B Pitsouli, Chrysoula,............. 153, 485B* Plaza, Serge, .............................. 163A* Pletcher, Scott, .................................23 Plummer, Zachary,....................... 377B Pohlmann, Regina, ...................... 185B Poisot, Emilie, .............................. 535A Poisot, Emily, ....................................88 Pokrywka, Nancy, ........................ 174C Polakiewicz, Roby, ....................... 824B Polena, Enio, ............................... 366C Polevoy, Gordon,.......................... 285C Pollock, John A., ......................... 643A* Pommier, Yves, ............................ 220A Ponting, Chris P., ......................... 772A Popichenko, Dmitry, .................... 235A* Popodi, E., ........................................76 Posakony, Jim,............................. 740B Posukh, Olga, ............................. 335B* Posukh, Olga V., .......................... 332B Pouya, Kheradpour, ..................... 749B Prantera, Giorgio, ........................ 260B Prazak, Lisa,.....................................59 Preibisch, Stephan, ..........................10 Pressman, Sigal, ......................... 770B Price, R.,...................................... 167B Prieto-Sánchez, Silvia, ................ 731B Pritchett, Tracy, ............................ 246C Pritchett, Tracy L., ........................... 52* Pronovost, Stephen, .................... 171C Przytycka, Teresa, ....................... 757A Puli, Oorvashi Roy G., ................ 659B* Purdy, Alexandra E., ................... 565A* Pyrowolakis, George,.................. 743B*

R Rabinow, Leonard,...................... 227B* Rach, Elizabeth, ...............................82 Radford, Sarah J.,.............297C, 298A* Rahme, Laurence, ..........................153 Rajan, Akhila, ...................................39 Rako, Lea, ................................... 473B Raley-Susman, Kathleen,............ 174C Ramachandran, Prasanna V.,...........95 Ramirez, Laura, ........................... 376A Ramos, Andrea I.,...........................109 Rana, Anil, ........................................94 Rana, Nadia A., ........................... 640A Rand, David,................................ 696C Rand, David M.,........................... 425B Rand, Matthew D., . 425B, 716B, 832A* Randle, Katherine,..........................149 Randsholt, Neel B.,...................... 258C Ranft, Jonas, ..................................106 Rao, Arvind,....................................129

SPEAKER AND AUTHOR INDEX

91

Rao, Yong,.................................... 389B Ratnappan, Ramesh,........444C, 478A* Raubenheimer, David, ................. 691A Rauskolb, Cordelia, ........................137 Ravi Ram, Kritipati,...................... 443B Ravisankar, Padmapriyadarshini, . 424A Raza*, Sameen, .......................... 569B Reddy, B. V. V. G., ........................ 310A Reddy, Hemakumar M., .............. 353B* Redmond, Seth,................................15 Reeves, Gregory T., ....................660C* Reinhardt, Josephine A., ............ 437B* Reinitz, John,............................... 683B Reis, Tania, ..................................... 17* Reiss, Kristina M.,........................ 206B Ren, Bing,.................................... 740B Renkawitz-Pohl, Renate, .............503B, 507C, 513C Repiso, Ada, .......................................2 Resnik-Docampo, Martin D.,....... 295A* Restifo, Linda L.,.........................378C* Reubens, Michael,........... 336C*, 815B Rex, Caitlin M., ............................ 836B Reyes Robles, Tamara,............... 286A* Riccardo, Sara, ............................ 282C Rice, Jesicca, .............................. 709A Richards, Adam, .............................122 Richards, Robert, ..............369C, 396C Richardson, Brian E.,..................207C* Richardson, Helena, ..............96, 299B, 367A Richardson, Helena E.,............... 311B* Riddle, Nicole C., .............337A*, 344B, 350B Ridyard, Marc, ............................. 635B Riekhof, Wayne,........................... 230B Riesgo Escovar, Juan Rafael,...... 679A Riesgo-Escovar, Juan Rafael, ..... 228C Rimkus, Stacey, ........................... 398B Rincon-Limas, Diego, .................. 408C Ríos-Barrera, Luis Daniel, ..........228C* Rivera, Melissa, ........................... 550A Riyue, Bao, .................................429C* Rizzo, Nicholas P., .......... 187A*, 744C* Robalino, Javier, ......................... 559A* Robbins, Renée M.,....................486C* Robbins, Zachary T.,................... 829A* Robin, Charles,............................ 459C Robinow, Steven,......................... 612C Robinson, Brian S.,......................... 64* Rochlin, Kate M., ........................510C* Rodrigues, Aloma, ....................... 286A Rodrigues, Aloma B.,.................. 283A* Rodriguez, Manuel S., ................. 768C Roger, Yvonne, ............................ 507C Rogers, Rebekah L.,...................438C* Roignant, Jean Y.,......................... 130* Rollins, Janet, ....................... 47, 543C, 547A, 550A Romanowicz, D.,...............................70 Rong, Yikang, .............. 77, 314B, 351C Rong, Yikang S., ......................... 326B* Ronsseray, Stéphane,.....................127 Röper, Jens-Christian,........................1 Rosenfeld, Michael G., ...................117

Rosenfeld, Robyn, ......................678C* Ross, Jermaine,.........119, 617B,745A* Rossiter, Sarah J., ............. 836B, 838A Roth, Caitlin E.,............................ 793A Roth, Therese M., ....................... 793A* Rotkopf, Shay,.............................. 173B Roubinet, Chantal,...................... 287B* Rousset, Raphael, ...................... 208A* Roy, Sougata, ............................. 179B* Roy, Swarnava,............................ 736A Royou, Anne, ............................... 293B Rual, Jean-François,.................... 816C Rubin, Gerald, ............................. 647B Rubin, Thomas, ................. 267C, 535A Rubinstein, Max,.......................... 696C Rudolph, Timothy, ........................ 788B Ruiz, Oscar E., ........................... 487A* Ruiz-Gómez, Ana, ..............................6 Ruiz-Gómez, Mar,.............. 504C, 731B Rulifson, Eric, .............................. 638B Ruohola-Baker, Hannele, ...............116 Ruse, Cristian, ............................. 250A Rushlow, Christine,............ 726C, 730A Rutter, Jared, ............................... 703A Ryan, Kathryn M.,....................... 746B* Rynearson, Shawn, ..................... 779B Ryoo, Hyung Don, ............... 138, 394A Ryu, Ellen, ................................... 496A

S Sabet, Ola,................................... 210C Sabin, Leah, ................................ 561C Sackton, Timothy, .......................447C* Sagner, Andreas,.............................. 1* Sahin, Brooke, ..................................92 Sahoo, Debashis, ........................ 292A Said, Amani, ...................................106 Saint, Robert, .....................................4 Saj, Abil, ..................................... 212B* Salah, Sally, ................................. 500B Saltz, Julia B.,............................. 457A* Salvadore, Christopher, ............... 824B Salz, Helen, ....................................102 Salzberg, Adi, ............................. 649A* Samaraweera, Saumya, .............. 396C Samboy, Jazlen, .......................... 475A Samper, Núria, ............................ 732C Sample, Christine, ...................... 661A* Samsonov, Alexander, ................. 683B Samsonova, Maria,...................... 683B Sanchez-Garcia, Jonatan, .........399C*, 408C, 768C* Sanders, Laura, ........................... 582C Sandhoff, Konrad,.............................21 Sandler, Jeremy, ................729C, 825C Sandova, Hector, ......................... 405C Sandoval, Hector, ........................ 407B Sandstrom, David J., ..................591C* Sanny, Justina, ............................ 165C Sanokawa-Akakura, Reiko,.......... 395B Sansores, Letitia,..............................65 Santhanam, Abirami, .................. 229A* Santos, Henrique,........................ 544A Sanyal, Subhabrata, .........................22

92

SPEAKER AND AUTHOR INDEX

Sapiro, Anne, ............................... 271A Sarhan, Moustafa, ....................... 748A Sarikaya, Didem P.,..................... 511A* Sarov, Mihail S.,.......................... 823A* Sartain, Caroline,........................ 551B* Sarthi, Jessica, ...........................327C* Sauert, Kathrin, ........................... 205A Savitskaya, Judith,..........................129 Savvateeva-Popova, Elena,......... 417C Scacheri, Peter, ........................... 357C Schaeffer, Stephen, ..................... 442A Schedl, Paul, ..................... 349A, 499A Schejter, Eyal D., ........................ 173B* Scherzer-Attali, Roni,................... 400A Schibler, Jeanine, .......................687C* Schindel, Heidi S., ...................... 256A* Schlenke, Todd A.,............................16 Schlichting, Karin,.............................68 Schlotterer, Christian, ................. 458B* Schmidt, Joshua, ........................459C* Schmidt, Kelsey A.,...................... 358A Schnakenberg, Sandra L.,...........239B, 750C Schnall-Levin, Michael,................ 831C Schneider, David, ...........................151 Schoen, Adam, ............................ 688A Schoen, Cynthia, ......................... 409A Scholz, Anne Kathrin,.................. 259A Schrider, Daniel R., .................... 460A* Schubiger, Gerold,...............110, 536B, 801C Schubiger, Margrit, ....................... 110* Schulze, K., ......................................76 Schulze, Karen, ................................75 Schulze, Karen L., ....................... 818B Schupbach, Trudi, ........................ 200B Schüpbach, Trudi, ............. 215B, 248B, 527B Schwartz, Yuri B.,.............. 337A, 344B, 347B, 350B* Schweisguth, Francois,................ 805A Schweppe, Nicole M.,.................. 523A Scoggin, Shane, .......................... 794B Scott, Anthony,............................. 339C Scott, Robert L., ......................... 592A* Scriappa, Lauren, ........................ 268A Sealfon, Rachel, .......................... 754A Searle, Elizabeth, ....................... 164B* Seay, Daniel,................................. 147* Segal, Daniel, ............................. 400A* Sehgal, Amita, ................... 695B, 761B Seifert, Matt, ................................ 628A Sekelsky, Jeff,.................... 251B, 290B Semnani, Sahar, .......................... 702C Sen, Aditya, ................................. 520A Sen, Anindya, ........................ 91, 413B Sergienko, Vyacheslav G.,........... 448A Serpe, M.,.................................... 178A Serrano, Yazmin L.,..................... 601A* Serway, C. N., ............................... 144* Sexton, T. R., ............................... 195C Sgrò, Carla, ................................. 707B Shaffer, C.,................................... 834C Shaffer, Chris,.............................. 328A Shah, Nikita, ................................ 342C

Shah, Saumini, ............................ 816C Shah, Waris, ................................ 308B Shalaby, Nevine A., .................... 794B* Shalovylo, Yulya, .......................... 373A Shamsian, Ash, ..............................112 Shang, Junjun,............................. 363C Shanower, Gregory,.................... 337A, 344B, 350B Sharma, Krishn,........................... 552C Sharma, Praveer,.......................... 107* Sharma, V., .................................711C* Shayo, Kalebi C., ........................ 401B* Shelly, Spencer,........................... 564C Shelton, Micah,............................ 835A Shen, Weiping, ............................ 175A Shi, Song, .................................... 339C Shi, Xiao, ........................... 405C, 407B Shilatifard, Ali,...................................84 Shilo, Ben-Zion, ........................... 173B Shim, Jiwon, ............................... 512B* Shimada, Yuko, .....................67*, 519C Shinwari, Riaz,............................ 625A* Shiu, Guan-Lin,............................ 663C Short, Sarah M., ......................... 461B* Shroff, Stuti,................................. 673A Shultz, Jeffrey, ............................. 422B Shvartsman, Stanislav, ...... 527B, 661A Shvartsman, Stanislav Y., ..... 56, 186C, 232A, 666C Si, Kausik,.......................................145 Sibon, Ody, ........................... 94*, 388A Siddall, Nicole,............................. 643A Sieber, Matt, ............................... 698B* Siegal, Gillian,.............................. 165C Siegal, Mark L., ........... 74, 239B, 750C Siegrist, Sarah E.,....................... 652A* Sierra, Javier,............................... 182B Silva, Elizabeth, ........................... 700A Silver Key, SC, ............................. 834C Silverman, Neal, .......................... 568A Sim, Choon Kiat,......................... 721A* Simcox, Amanda, ........................ 640A Simich, Michael, .......................... 735C Simmonds, Andrew J.,....... 218B, 368B Simonette, R. A.,...............................70 Simonova, Olga B.,..................... 529A* Simpson, Ian,....................................42 Simpson, Julie, ............................ 620B Sing, Anson, ................................ 678C Singh, Amit, ...................... 268A, 397A, 642C, 659B, 669C Singh, Carol M.,.................385A, 402C Singh, Nadia, .............................. 439A* Singh, Neetu,............................... 327C Singh, Shree Ram, .........................104 Singh, Sukhdeep, ........................ 376A Sinha, Saurabh,..............................122 Sinsimer, Kristina S., .................. 785B* Sirohi, Neha,.....................692B*, 788B Sismeiro, Odile, ................................88 Sisson, John C., .......................... 250A Sitnik, Jessica Lynn, ................... 602B* Skora, Andrew, ........................... 760A* Slawson, Justin,.......................... 412A* Sly, William S., ............................. 185B

Smibert, Craig, ............................ 773B Smith, C. I. Edvard, ...................... 799A Smith, Frank, ......................................9 Smith, Melanie,............................ 413B Smith, S., ..................................... 834C Soldaat, Candice, ........................ 491B Somers, Greg, ............................. 651C Somers, Jason,............................ 590B Son, Wonseok, ............................ 374B Song, Xingzhi, ............................. 723C Song, Yan,................................... 653B* Song, Yanjun,................................ 113* Sood, Pranidhi, .................................57 Sopko, Richelle,.......................... 824B* Sorokina, Svetlana Y.,................. 440B* Sorokina, Svetlana Yu.,................ 448A Soshnev, Alexey A., ......... 516C, 771C* Soumana, Djade,......................... 831C Southall, Tony D.,............................103 Southard, Sheryl,........................ 539B* Sowers, Levi, ............................... 375C Spana, Eric, ......................................82 Spasic, Milos R.,......................... 188B* Spéder, Pauline, .......................... 208A Speese, Sean, ................................115 Spirov, Alexander V.,.........680B, 682A* Spokony, Rebecca,...................... 740B Spokony, Rebecca F., ................. 806B* Spradling, Allan, .......................... 760A Spradling, Allan C.,.............. 139, 818B Spratford, Carrie M., ................... 665B* Sprecher, Simon, ......................... 644B Sridhar, Vasanthi,......................... 413B Stahley, Sara, .............................. 777C Stalker, Heather, .........................288C* Stamm, J., ................................... 834C Stanley, Bruce A., ........................ 820A Staple, Douglas, .................................1 Stapleton, Mark, .......................... 816C Stark, Alexander, ............... 743B, 754A Stark, William S., ......................... 185B Starks, Adrienne M.,................... 472A* Starz-Gaiano, Michelle, .....204C, 555C Stathopoulos, Angelike, ..... 660C, 766A Steinberg, Barrett, .............574A, 576C Steinhauer, Josefa,..................... 230B* Steller, Hermann,......................... 275B Stempfle, Denise, ........................ 212B Stenberg, Per,............................. 361A* Stern, David,................................ 420C Stettler, Karin,............................. 370A* Stevens, Kristian,......................... 460A Stevens, Laura J., ....................... 209B* Stevens, Traci L., ......................... 206B Steward, Ruth,................... 304A, 560B Stewart, Bryan A., ....................... 308B Stewart, Judy, .............................. 390C Stinchfield, Michael,........... 631A, 658A St. Johnston, Daniel,.... 31, 172A, 296B Stone, Hunter H.,......................... 549C Stosic, Christina D., ..................... 436A Stramer, Brian,............................210C* Stronach, Beth,........................... 712A* Strutt, David,........................ 105, 164B Strutt, Helen, ............................... 164B

Students, Bio4342, ...................... 328A Stultz, Brian, ................................ 266B Sturdivant, Patrick,......................213C* Sturgill, David, ..................807C, 812B* Su, Ming-Tsan, ............................ 392B Su, Ying, ..................................... 688A* Subramaniam, Vinod, .........................5 Subramanian, Ramanand A., ...... 436A Suchy, Sarah, .................... 740B, 806B Sugimura, Kaoru,..............................62 Suh, Yoon Seak, .......................... 278B Suissa, Yaron, .............................. 499A Sukumar, Sumitha, ...........................95 Sullivan, Bill, ........................... Opening General Session Sullivan, William,................ 284B, 293B Sun, Fengzhu, ............................. 582C Sun, Lin, .....................................480C* Sun, Mingkuan,........................... 655A* Sun, Y. Henry, ..........629B, 671B, 675C Sun, Yi, ........................................ 200B Sun, Yi Henry, .............................. 482B Sung, Carl S., .............................. 612C Sung, Hsin-Ho, ............................ 183C Sung, Ying Ying,.......................... 619A* Supatto, Willy, ............................. 5, 80* Susic, Loreen,.............................513C* Sustar, Anne, ....................... 110, 536B Sustar, Anne E.,..........................801C* Suter, Beat,.................................. 370A Suzanne, Magali,......................... 208A Svitin, Anton, ............................... 253A Swan, Andrew,..................... 133, 245B Swanson, Selene,........................ 315C Swanson, Selene K., ........................53 Swarup, Shilpa, ..........................603C* Symonds, Jim, ............................. 402C Symonds, Jimmy,......................... 385A Szalay, Daniel, ............................. 431B Szlanka, Tamás, .......................... 247A Sznajder, Jacob I., ....................... 221B Szuperak, Milan,......................... 500B*

T Taghli-Lamallem, Ouarda, ..............117 Tajiri, Reiko, ................................ 497B* Takaesu, Norma, ............... 631A, 658A Takahashi, Aya, ........................... 462C Takahashi, Kazuo H.,.................. 473B* Takahashi, Takashi, ........... 264C, 269B Takano-Shimizu, Toshiyuki,462C, 473B Takeuchi, Hideyuki,............ 161B, 640A Takino, Kyoko,...................................62 Talamillo, Ana, ...................693C, 768C Tamada, Masako, ........................ 165C Tamara, Natalia, .......................... 383B Tamir, Tigist,................................. 538A Tamori, Yoichiro,................281B*, 662B Tan, Change, ............................... 526A Tan, Julie,.................................... 530B* Tan, Kai Li,.................................. 304A* Tan, William, ............................... 560B* Tan, Zehu,.................................... 744C Tanaka, Akemi J., ....................... 514A*

SPEAKER AND AUTHOR INDEX

93

Tanaka, Kentaro M.,....................462C* Tanda, S., .................................... 167B Tanda, Soichi, ............................. 571A* Tanentzapf, Guy,................112, 198C*, 489C, 490A, 496A Tang, Hong-Wen,......................... 217A Tang, Jessica,............................. 566B* Tang, Jonathan C. Y., ................... 635B Taniguchi, Kiichiro,..........................108 Taniguchi, Kiichirou,..................... 223A Tank, David,................................. 249C Tanner, Elizabeth A.,..................... 134* Tao, Chunyao,...................................65 Tao, Hirotaka,............................... 375C Tare, Meghana,................ 642C, 669C* Tasdemir, Ozge,........................... 579C Tatar, Marc,........................... 18*, 464B Taylor, Chad,................................ 604A Technau, Gerhard,....................... 627C Ten Hagen, Kelly G.,.................... 689B Tennessen, Jason M.,..................... 20* Terman, Jonathan,....................... 615C Terry, Natalie,............................... 804C Teysset, Laure, ...............................127 Thackeray, Justin R., ..................189C* Theodore, Laurent, ...........................88 Théodore, Laurent, ......... 267C*, 535A* Theopold, Ulrich, ............................154 Thomas, Archana, ....................... 390C Thomas, Graham H., ................... 820A Thomas, Joëlle, ........................... 633C Thompson, James N., ................474C* Thompson, Morgan, .................... 323B Thompson, Rhea, ........................ 376A Thummel, Carl, .................... 147, 698B Thummel, Carl S.,........20, 703A, 759C Tian, Ai, ............................. 242B, 244A Tian, Ai-Guo, .............................. 662B* Tian, Ling,.................................... 704B Tie, Feng,....................................357C* Tien, An-Chi,.....................................39 Timmons, Allison, ........................ 262A Tiong, Stanley, ............................. 700A Tipping, Marla,............................. 307A Toda, Nicholas, .................................36 Toder, Moran,............................... 649A Todeschini, Anne-Laure,.................127 Togane, Yu, ........................ 264C, 269B Tögel, Markus,............................ 515B* Toledo Melendez, Natalia, ........... 662B Tolstorukov, Michael, .................. 337A, 344B, 350B Toma, Daniel P.,.......................... 604A* Tomacak, Pavel, .......................... 823A Tomancak, Pavel, .................. 10, 827B Tomkiel, John E., ........................552C* Tomoyasu, Yoshinori, ................... 424A Tong, Chao, .................................... 39* Tonkin, Leath A.,.......................... 756C Toomey, Michelle, ..............574A, 576C Tootle, Tina L., ............................531C* Topper*, Michael,......................... 569B Torroja, Carlos, ............................ 182B Toth, Meridith, .............................345C* Toth Lorbeck, Meridith, ................ 342C

Toups, Melissa A., ......................441C* Tracey, Daniel W., ........................ 593B Tracey, W. Daniel,............................143 Tracey Jr., W. Daniel, ................... 648C Tracy, Charles, ................................150 Tran, Duy D.,................................ 689B Tran, Susan L., .................. 187A, 190A Traore, Sekou, ..................................15 Travaline, Tara L.,........................ 605B* Travencolo;olo, Bruno AnN, ......... 680B Treisman, Jessica, ...............130, 230B, 654C Trucco, Alvar, ......................131*, 783C Truong, Thai V., .................................80 Tsachaki, Maria, ......................... 644B* Tsai, Yu-Chen, ............................ 670A* Tseng, Alexander M., ................. 536B* Tsubota, Stuart I.,........................ 744C Tsujimura, Hidenobu,......... 264C, 269B Tsurumi, Amy,.............................. 365B Tudor, Cicerone, .................................5 Tulin, Alexei,................83*, 216C, 791B Turkel, Nezaket,................................96 Turnock, Daniel,........................... 205A Tutor, Antonio S., ........................ 731B* Tyson, Leonard, ..............................119 Tze, Newman,.............................. 619A

U Ueda, Hitoshi, .............................. 748A Ueno, Naoto,................................ 375C Ugrankar, Rupali B., ...................699C* Uhl, Juli D., .................................747C* Um, Chae-Yoon, .......................... 702C Umeh, Maxine, ............................ 650B Umetsu, Daiki, .............................. 106* Umulis, D., ................................... 178A Uppendahl, Locke D., .......................74 Urnov, Fyodor, ................................124 Uruena, Ana, ............................... 543C Uvell, Hanna, ............................... 572B

V Vaidya, Namita, ........................... 816C Vaidya, Pujita,.............................. 816C Valentine, Meagan,.....................180C* Van Aalten, Daan,........................ 205A van Belle, Werner, ....................... 212B VanBerkum, Mark F. A., ............... 632B Vanderploeg, Jessica, ................. 498C Van Doren, Mark,.................. 48, 508A, 539B, 540C van Eyk, Clare, ............................ 396C Van Gilst, Marc, ................................17 Van Sorge, Nina, ..............................97 Van Vactor, David, ....................91, 126 Van Vactor, David L., .................. 413B* Vargas, Diego, ............................. 420C Vargas, Eric, ................................ 797B Vaughan, Alexander G.,................ 141* Vaughn, Jack, .............................. 790A

94

SPEAKER AND AUTHOR INDEX

Vazquez Paz, Luz de Lourdes, ....491B, 498C* Vega-Rioja, Antonio, .................... 172A Vendra, Georgia, ......................... 782B Venken, K., .......................................76 Venken, Koen, ............................. 806B Venken, Koen J. T., ............... 75*, 818B Veraksa, Alexey,................. 307A, 553A Verboon, Jeffrey M.,..........................30 Verghese, Shlipi,......................... 268A* Vermehren, Anke,.......................606C* Vermeire, Wendy,......................... 188B Veverytsa, Lyubov,...................... 598A* Vibranovski, Maria D.,.................. 545B Vichas, Athea, ............................165C* Vietti, Dana L., ............................. 523A VijayRaghavan, K., ...................... 816C Viktorinova, Ivana, ............................68 Villalta, Jacqueline E., ................. 756C Villaluz, Alfred T., ............. 385A, 402C* Vincent, Alain,.................... 506B, 558C Vincent, Jean-Paul, ..................... 240C Vining, Melissa, ................................72 Virágh, Erika,............................... 247A Vishal, Kumar, ............................ 236B* Visk, DeeAnn W.,........................414C* Vitalini, Michael W.,..................... 338B* Vitaly, Gursky, ............................. 683B* Vlachos, Stephanie,.................... 238A* Voelker, Dennis,........................... 230B Voelzmann, André, ...........................21 Voinnet, Olivier,.................................88 Volk, Talila,...................................... 71* Volpi, Silvia, ................................ 260B* von Hilchen, Christian,................. 627C Von Ohlen, Tonia, .............................55 Voog, Justin, ................................. 103* Vorontsova, Julia, ........................ 529A Vose, Linnea R., ......................... 596B* Vrailas-Mortimer, Alysia D., ............ 22* Vuilleumier, Robin,....................... 743B Vyas, Aditi,................................... 571A

Wang, Qian,................................ 263B* Wang, Shiuan, ............................276C* Wang, Shu,.................................. 420C Wang, Xiaobo, ..................202A, 826A* Wang, Xiaochen, ........................501C* Wang, Xiaohong, ........................ 770B* Wang, Ying, ................................. 704B Wang, Yiwen, ............................... 797B Wang, Yu-Chiun, ......................... 199A* Wang, Yu-Chun,.......................... 403A* Wang, Zhe, .................................. 594C Wang, Zhi, .................................... 154* Wang, Zhipeng, ..........................567C* Ward, Megan, ...................................78 Ward, Robert, ......... 213C, 484A, 501C Waring, Gail,................................ 517A Warrick, John M.,........................ 404B* Warrington, Samantha J., ............. 105* Washburn, Machael P., ................ 315C Washburn, Michael P., ......................53 Wassarman, David, ..................... 398B Wasserman, Steven A., ............... 415A Watanabe, Takahito, .................... 674B Watnick, Paula, ............................ 565A Watnick, Terry, ............................. 410B Watson, Joseph,.......................... 630C Watson, Joseph D.,......................... 43* Wawersik, M., .............................. 834C Wawersik, Matthew,..................... 538A Wayne, Marta L., ......................... 476B Wculek, Stephanie,...................... 201C Weake, Vikki M., ............................. 53* Weasner, Bonnie, .......................672C* Webb, Watt W., .................................58 Weber, Christopher M.,............... 346A* Weckerle, Frank,.......................... 650B Wehling, Misty D., ........................ 771C Weiner, Molly, ...................................87 Weiss, Alex, ................................. 743B Weiszmann, Richard, ..................725B, 749B, 825C Welte, Michael, ............................ 225C Welte, Michael A.,....................... 187A, 190A*, 192C Wen, Pei, ....................................795C* Wen, Ying-Hao,............................ 663C Wen, Yuhui,................................. 626B* Wesolowska, Natalia, ........... 77*, 314B Wessells, Robert, ..............697A, 708C Wessells, Robert J.,........................117 Wetzel, Randall,........................... 824B Wharton, Keith, Jr., ...........................72 Wheeler, Scott, ............................ 630C Wheeler, Scott R.,.............................43 White, Benjamin, ............... 584B, 588C White, Kevin,.............. 111, 740B, 806B Whitworth, Cale, .........................540C* Wibom, Rolf, ................................ 762C Widmann, Thomas,.........................106 Wiegand, Roger,...............................15 Wieschaus, Eric,............... 199A, 249C, 527B Wieschaus, Eric F., ...........................25 Wilhelm, James, .................132*, 780C Wilhelmsson, Christine, ..................154

W Wagner, Ulrich, ............................ 740B Waheed, Abdul, ........................... 185B Wakimoto, Barbara T., ................. 260B Walcott, Kia C. E.,.......................648C* Walker, Amy K., ........................... 413B Wallace, Andre, .......................... 442A* Wallenfang, Matthew R.,.............705C* Wallrath, Lori L., ........... 49, 115*, 338B Walters, Jenna,.................................73 Waltzer, Lucas, ............................ 163A Wan, Kenneth, ...................729C, 816C Wan, Kenneth H., .......................825C* Wang, Cheng-Wei, ..................... 671B* Wang, Dakun,.............................. 365B Wang, Dennis, ....................... 41, 625A Wang, Dong,................................ 191B Wang, Hui,................... 79, 723C, 814A Wang, Jian,........................ 355A, 704B Wang, Keqing, ..................... 118, 723C Wang, Liguo,................................ 814A

Williams, Calvin, .......................... 383B Williams, Michael,........................ 556A Williamson, W. Ryan, .................. 191B* Wilson, Patricia G., ...................... 548B Wingert, Lindsey, ......................... 804C Wiora, H. W.,.....................................70 Wirth, Dyann,....................................15 With, Sheila Irene, ....................... 655A Witt, Lorraine, .............................. 637A Wittkopp, Patricia,........................ 423C Wittkopp, Patricia J., .........................13 Wodarz, Andreas, .............................26 Wolf, Fred W., ............................. 362B* Wolfe, Kelly A.,............................. 251B Wolfe, Scot, ....................................122 Wolfner, Mariana, ........ 50, 551B, 602B Wolfner, Mariana F.,.......... 443B, 468C, 534C Wong, Jeannette,........................ 328A* Wonglapsuwan, Monwadee,....... 532A* Woo*, Won,.................................. 569B Wood, Carla,................................ 538A Wood, Cricket G., ........................ 548B Wood, Jamie L.,........................... 737B Wood, Will,................................... 210C Woodfield, Sarah E.,................... 181A* Woodruff, Ronny C., ...... 463A*, 836B*, 837C*, 838A* Workman, Jerry L., ...... 53, 315C, 341B Wredenberg, Anna, ..................... 762C Wreh, Elijah, ................................ 604A Wright, Victoria, ........................... 193A Wright, Victoria M., ..................... 196A* Wu, Chao-ting,............................. 356B Wu, Chun-Fang, .......................... 594C Wu, C.-ting,.................................. 323B Wu, Guan, ................................... 365B Wu, Jianhong,.............................. 323B Wu, Louisa,................ 149, 559A, 566B Wu, Louisa P., ..........222C, 263B, 554B Wu, Ming, ................................... 371B* Wu, X.,......................................... 763A Wu, Yi, ......................................... 826A Wyskiel, Emily R.,....................... 673A*

X Xi, Rongwen, ......................... 98, 795C Xie, Ting,...................Plenary Session I Xie, Wei, ...................................... 655A Xie, Weiwu,................................. 769A* Xie, Xuanhua, ............................. 214A* Xin, Nan,...........................242B, 244A* Xing, Guanglin, ............................ 655A Xing, Yalan, ................................... 100* Xiong, Bo, ........................ 405C*, 407B Xu, Dongbin,................................ 275B Xu, Jie,........................................561C* Xu, Kanyan, ......................695B, 761B* Xu, Mu, .................................. 69, 509B Xu, Na,..................................98, 537C* Xu, Tian, ...................... 62, 371B, 494B Xu, Xin, ....................................... 634A* Xu, Yifan, ........................................143 Xue, Jin,....................................... 416B

Y Yacobi-Sharon, Keren,................. 274A Yadlapalli, Swathi,....................... 796A* Yakoby, Nir, ........................ 177C, 427A Yam, Kylee,.................................. 475A Yamamoto, Aki,............................ 445A Yamamoto, Akihiko, .................... 607A* Yamamoto, Akihiko H.,................. 601A Yamamoto, Daisuke, .......... 583A, 799A Yamamoto, Haruka, ........................108 Yamamoto, Rochele,.........................18 Yamamoto, Shinya, ...................... 407B Yamamoto, Yutaka, ....................... 124* Yamashita, Yukiko M., ........ 793A, 796A Yamin, Bibi Shalimar,................... 547A Yamomoto, Shinya, ...................... 405C Yan, Hua, ....................................312C* Yan, Jie, ....................................... 162C Yan, Shian-Jang,.........................339C* Yan, Yan, ...........................200B, 215B* Yang, Chun-Yen, .......................... 392B Yang, Jacob, ................................ 621C Yang, Jacob Sun-Jen,.......................40 Yang, Li,....................................... 729C Yang, Shun-Jen J.,...................... 620B* Yang, Shu Yuan,.............................. 48* Yang, Taehong, ...........................615C* Yang, Xiaohang, ......................... 616A, 619A, 651C Yang-Zhou, Donghui,................... 830B Yarrington, Bryan, ....................... 839B* Yassin, Amir, ...............................450C* Yates, John R., III,........................ 250A Yavatkar, Amar S., ..........................119 Ye, Honggang, ............................. 383B Yee, William, ................................ 831C Yin, Chong,.................................645C* Yin, Hang,.........................................87 Yokokura, Takakazu, .............. 91, 413B Yonas*, Nebyat, ........................... 569B

SPEAKER AND AUTHOR INDEX

95

Yoo, Ook-Jun, .............................. 374B Yorimitsu, Takeshi, ....................... 659B Yoshihara, Moto, ......................... 584B* Yoshizaki, Masato, ....................... 426C Young, Robert S., ....................... 772A* Yu, Amy Marie, ............................ 252C Yu, Charles, ................................ 729C, 816C, 825C Yu, Huang-Hsiang,............................40 Yu, Hung-Hsiang,............... 620B, 639C Yu, Hung-Hsiang Sam, ...............621C* Yu, Kweon,.........................381C, 597C Yu, Kwon,..................................... 702C Yu, Yanxun V., .............................192C* Yuan, Lin,........................... 198C, 490A Yuan, Liudi, .................................. 655A Yuan, Rong, ................................. 279C Yun, Amber, ................................. 587B

Zhang, Huamei, ........................... 522C Zhang, Junzheng,........................ 688A Zhang, Ke, ........................405C, 407B* Zhang, Kun, ......................................79 Zhang, Liang,..................... 213C, 484A Zhang, Liping,............................. 689B* Zhang, Qiao,............................... 533B* Zhang, Sophia, ............................ 645C Zhang, Weiguo,............................... 86* Zhang, Xiaomeng, ....................... 302B Zhang, Yan,...................... 399C, 408C* Zhang, Yanping, ........................... 279C Zhang, Yizhi, ................................ 751A Zhang, Yu,.................................... 807C Zhao, Huiwen W.,........................ 415A* Zheng, Qi,................................... 797B* Zheng, Xiao-Feng,....................... 351C Zhimulev, Igor, ............................. 335B Zhimulev, Igor F.,.......................... 347B Zhong, Hua,................................ 257B* Zhong, Lixian, ............................. 593B* Zhou, Dan,............................ 93, 414C, 415A, 416B* Zhou, L., ...................................... 834C Zhou, Lei,...........................279C, 348C Zhou, Pei, ....................................... 85* Zhou, Rui, .................................... 561C Zhou, Xianchong, ........................ 406A Zhou, Xin, ....................................... 29* Zhu, Alan Jian,............................. 688A Zhu, Jun,...........................................82 Zhuo, Ran,.................................. 700A* Zhuravlev, Alexandr, .................... 417C Zieba, Jennifer, .................. 740B, 806B Zimmerman, John E., ................. 608B* Zipfel, Warren, ..................................58 Zipursky, Larry,Plenary Session*, 647B Zirbel, Luka,....................................115 Zobeck, Katie L.,............................. 58* Zola, Sheri, .................................. 282C Zur Lage, Petra,................................42

Z Zallen, Jennifer, ........................... 165C Zang, Shaoyun, .......................... 406A* Zaretsky, Jesse,........................... 512B Zartman, Jeremiah J.,.................666C* Zavortink, Michael, .............................4 Zeidler, Martin,............................. 193A Zeidler, Martin P.,......................... 196A Zeina, Rami K.,............................ 632B Zelentsova, Helen S., .................. 448A Zelhof, Andrew,............................ 377B Zeng, Shu-Heng, ......................... 663C Zeng, Xiankun, ................... 104*, 655A Zervos, Ashley A., ...................... 329B* Zhai, Bo, ...................................... 816C Zhai, Grace,....................... 406A, 713B Zhai, R. Grace, ............................ 626B Zhang, Bingqing, ........................ 277A* Zhang, Can,................................. 348C Zhang, Huadi, .............................174C*

96

KEYWORD INDEX

The following index is composed of keywords selected by presenting authors from a list in the Conference Call for Abstracts. Abstracts program number follow each keyword. NCell biology and signal transduction autophagy 217A 222C

notch 211A 212B 213C 214A 215B nucleolus 216C

carbon dioxide 221B

protein tyrosine phosphatase 229A

cell polarity 1 2 7 162C163A164B165C

31 157A 158B 159C 160A 161B

cytoskeleton 25 26 27 171C172A173B174C

28 166A 167B 168C 169A 170B

dmyc 224B dpp 175A 176B 177C 178A 179B endocytosis 180C 181A

receptor tyrosine kinase/phosphatase 231C 232A 233B 234C 235A 236B rho gtpases 237C 238A RNA processing 227B secretion 29 239B 240C 241A septate junction 223A tdp1

hedgehog 6 182B

220A

hippo 8

wingless 4 242B 243C 244A

injury response 219C

wound healing 30

intracellular transport 3 183C 184A 185B 186C 187A 188B 189C 190A 191B192C

NCell cycle and checkpoints

JAK/STAT 193A 194B 195C 196A JNK 228C lipid droplet 225C live imaging 5 197B 198C 199A membrane and phospholipid biology 230B migration 200B 201C 202A 203B 204C 205A 206B 207C 208A 209B210C muscle attachment 218B myoblast fusion 226A

APC 245B checkpoint 136 246C 247A 248B 249C developmental modulation 139 250A DNA repair 251B 252C DNA replication 133 135 140 253A 254B 255C 256A 257B kinase/phosphatase/cyclin 258C 259A meiotic cell cycle 260B

KEYWORD INDEX

97

TOR 295A

NCell death apoptosis 277A

tumor suppressors and oncogenes 305B 306C 307A 308B 309C 310A 311B 312C

autophagy 261C 262A 263B caspases 264C 265A 266B 267C 268A compensatory proliferation 276C death mutants/genes 269B 270C 271A

NChromatin and epigenetics chromatin assembly 313A 314B 315C 316A chromatin structure 317B 318C 319A 320B 321C 322A 323B 324C 325A 326B327C328A329B DNA repair 352A

drosophila p53 275B inhibitors of apoptosis (iaps) 138 272B 273C mitochondrial dynamics 134 noncanonical cell death 274A physiological apoptosis 278B transcriptional regulation 279C

NCell division and growth control cell competition 62 280A 281B cell growth 66 282C 283A cellularization 60

epigenetics 87 heterochromatin 88 330C 331A 332B 333C 334A 335B 336C 337A 338B339C histone variants and modifications 83 86 340A 341B 342C 343A 344B 345C 346A insulators/boundary elements 89 90 347B 348C 349A 350B meiotic sister-chromatid cohesion 85 polycomb/trithorax complexes 84 354C 355A 356B 357C remodeling complexes 358A 359B 360C 361A telomere 351C 353B

NDrosophila models of human diseases

cytokinesis 284B 285C 286A 287B 288C

addiction 362B behavior 412A

insulin 61 meiosis 289A 290B

cancer 96 118 363C 364A 365B 366C 367A 368B 369C 370A371B

mitosis 291C 292A 293B

cardiovascular 113 114 117

spindles and motors 296B 297C 298A

deafness 409A

SUMO and proliferation 294C

developmental disorders 372C 373A 374B 375C 376A 377B 378C

tissue growth 63 64

diabetes and obesity 95 379A 380B 381C 382A 383B

65 299B 300C 301A 302B 303C 304A

98

KEYWORD INDEX

drug discovery 94 384C 385A hyperoxia 415A hypoxia 414C HYPOXIA 93 hypoxia tolerance 416B

genome evolution 13 34 36 120 121 430A 431B 432C 433A 434B435C436A437B 438C 439A 440B 441C 442A host-parasite coevolution 16 phylogenetics 448A 449B 450C population variation 32 33 37 38 451A 452B 453C 454A 455B 456C457A458B459C 460A 461B 462C 463A

inflammation 411C

quantitative traits 464B 465C 466A 467B 468C 469A 470B 471C 472A 473B474C

laminopathy 115

rapid protein evolution 123

muscular dystrophy 116

recombination 444C

myopathy 112

speciation 15 475A 476B 477C 478A

neural degeneration 91 92 386B 387C 388A 389B 390C 391A 392B 393C394A395B396C 397A 398B 399C 400A 401B 402C 403A404B405C406A 407B 408C

sperm storage 443B transposons 445A

polycystic kidney disease 410B small RNAs 417C spinal muscular atrophy 413B toxins 97

NEducational initiatives college/university curriculum 833B 834C 835A 836B 837C 838A 839B

NGametogenesis and organogenesis dosage compensation 479B 480C ectodermal derivatives 72 73 481A 482B 483C 484A 485B 486C 487A egg activation 534C extracellular matrix/cell adhesion 51 488B 489C 490A 491B 492C 493A 494B 495C 496A497B498C imaginal disc morphogenesis 74 499A 500B 501C

NEvolution and quantitative genetics evolution and development 9 10 11 418A 419B 420C 421A 422B 423C 424A425B426C427A 428B 429C evolution of gene expression 446B 447C evolution of gene regulation 14 genetic conflicts 35 genetic interactions 12

mesodermal derivatives 69 71 502A 503B 504C 505A 506B 507C 508A 509B510C511A512B 513C 514A 515B oogenesis 49 50 52 67 68 516C 517A 518B 519C 520A521B522C523A 524B 525C 526A 527B 528C 529A 530B531C532A533B ovarian morphogenesis 535A regeneration 536B

KEYWORD INDEX rho, DAAM, salivary gland 537C

learning/memory 144 145 594C 595A 596B

sex determination 46 538A 539B 540C

neuropeptides 142 597C 598A

sex-specific traits and molecules 48 541A

neurotransmitters 148 599B 600C

spermatogenesis 47 70 542B 543C 544A 545B 546C 547A 548B 549C550A551B552C

post mating response 602B

99

sensory 609C 610A 611B

NImmunity and pathogenesis cellular immunity 149 150 553A 554B 555C 556A 557B 558C 559A 560B561C host/pathogen interaction 153 154 155 562A 563B 564C 565A 566B 567C

sleep 608B startle response 601A startle-induced locomotion 607A

humoral immunity 151 568A 569B 570C stem cells 571A transcriptional regulation 152 156 572B 573C Wolbachia 574A 575B 576C

NNeural physiology and behavior alcohol 146 atypical soluble guanylyl cyclase 606C

NNeurogenetics and neural development axon guidance 39 612C 613A 614B 615C cellular neuroanatomy 647B CNS 45 616A 617B 618C 619A 620B 621C dendrites 41 622A 623B 624C 625A 626B fiber architecture 646A glia 43 627C 628A 629B 630C

chemosensation 603C circadian rhythms 577A 578B 579C courtship and mating 141 580A 581B 582C 583A 584B eating 147 585C 586A flight 605B geotaxis 604A hormones 587B 588C ion channels 143 589A 590B 591C 592A 593B

hormonal control 631A neuronal morphogenesis 632B 633C 634A neuronal specification 40 42 44 635B 636C 637A 638B 639C 640A 641B642C643A644B 645C nociception 648C sensory 649A stem cells 650B 651C 652A 653B synaptogenesis 654C 655A

100

KEYWORD INDEX

NPattern formation axis specification 105 108 656B 657C 658A 659B 660C 661A 662B cell migration and motility 663C 664A compartments and boundaries 106 109 665B 666C eye 678C eye disc 667A 668B 669C 670A 671B 672C homothorax 675C leg disc 110 673A non-Drosophila patterning 674B planar cell polarity 107 segmentation 111 679A 680B 681C 682A 683B

physiology of adult organs 19 stress response 22 23 24 706A 707B 708C 709A 710B 711C 712A

RNA biology miRNA 126 770B non-coding transcripts 771C 772A RNA binding proteins 130 773B 774C 775A 776B 777C RNA elongation and stability 778A 779B RNA localization 131 132 780C 781A 782B 783C 784A 785B small RNAs 127 128 786C splicing and its regulation 129 787A 788B 789C 790A

terminal filament formation 676A

NRegulation of gene expression

thoracic muscle 677B

activators/coactivators 53 713B 714C 715A 716B 717C 718A 719B 720C 721A

wing disc 684C 685A 686B 687C 688A 689B

circadian 761B

NPhysiology and aging

computational instance identification 754A

dietary restriction 690C 691A 692B

copy number variation, gene expression 757A

endocrine function 18 693C 694A

core promoters and general transcription factors 58 82 722B 723C 724A 725B 726C 727A 728B 729C730A731B

juvenile hormone 704B metabolism 20 21 695B 696C 697A 698B 699C 700A mitochondrial function 703A

developmental timing 748A dosage compensation 753C 758B

nutrient sensing 17 701B

enhancers 54 59 122 125 732C 733A 734B 735C 736A 737B738C739A740B 741C 742A 743B 744C 745A 746B 747C

nutrition 702C

heterochromatic gene regulation 755B

oxidative damage 705C

inheritance 760A

KEYWORD INDEX micro RNA 750C

NTechniques and functional genomics chipchip 806B

position effect 752B position effect variegation 56 repressors/corepressors 55 762C 763A 764B 765C 766A 767B 768C 769A sex-specific/temporal regulation 756C stochastic gene expression/robustness 57

chipseq 807C chromatin preparation 822C computational analyses 119 808A 809B 810C 811A 812B database 821B gene and transcript mapping 78 813C 814A

transcription factors 749B transcription start sites 751A xenobiotics, transcriptional regulation 759C

gene disruption and targeting 75 77 124 membrane proteomics 820A microscopy 80

NStem cells germline and somatic stem cells 800B germline stem cell 99 100 101 796A797B

molecular interactions 81 815B 816C mutational screens 79 817A 818B 819C

102 791B 792C 793A 794B 795C

maintenance 137 niche 103 798C 799A regeneration 801C signaling 104 802A somatic stem cell 98 803B 804C 805A

phosphoantibodies 824B photoactivation 826A protein tagging 823A recombination systems 827B 828C 829A resources 825C RNAi 830B 831C small compounds 832A X chromosome duplications 76

101

102

FLYBASE GENETIC INDEX TO ABSTRACTS

This is an index of genes mentioned in the abstracts. The current FlyBase-approved gene symbol is given in each case; non-current symbol synonyms or full names used in the abstracts are not indexed. The index was prepared computationally by FlyBase, based solely on the FBgn & gene symbol information provided by authors during abstract submission. We have performed a cross-check between the FBgn and gene symbol provided to ensure we have indexed the intended gene. However, FlyBase is not responsible for any omissions from the index where authors did not provide information, nor for any incorrect indexing where genes were stated to feature in an abstract but do not actually do so. Indexed terms are in bold. Numbers following each term refer to abstract program numbers: 1–156 are platform presentations and 157–839 are poster presentations.

5-HT7........................................... 581B Aats-met ..................................... 386B ab ...................................... 9, 96, 157A abd-A .......................................... 763A ac.......................................739A, 771C Acp70A .............................443B, 468C Act5C ...............................................65 Act88F......................................... 741C Actn................................................114 ade2 ............................................ 706A AGO2..................................... 88, 575B AGO3................................................37 Akap200...................................... 362B Akt1............................................. 158B al.......................................................74 ald ............................................... 523A Alk ............................................... 235A Amyrel ........................................ 450C aop .............................................. 228C ap ................................ 74, 349A, 635B AP-2 .................................................74 aph-1 ........................................... 414C aPKC ........................................... 311B argos..................................... 55, 630C arm ..................... 4, 242B, 418A, 429C armi ............................................. 522C atg ............................................... 652A Atg1............................................. 262A Atg6............................................. 222C Atg7............................................. 262A ato ......................................... 42, 641B Atox1................................. 374B, 395B ATP7............................................ 374B AtpA ............................................ 223A aub ...................................................37 aur ............................................... 259A aux ...................................................29 B-H1 ............................................ 686B B-H2 ............................................ 686B bab1 .............................. 9, 511A, 535A bab2 ............................................ 535A bam .................102, 419B, 791B, 795C baz........................................... 7, 165C bcd .............................. 56, 174C, 682A BEAF-32...................................... 736A ben .............................................. 568A BicC ............................................ 774C

Blimp-1 ....................................... 748A bnl ............................................... 482B bon .............................................. 583A bowl ............................................ 686B br ........................................... 96, 521B brk ............................................... 743B Bruce .............................................138 bs ................................................ 679A bsk ....................63, 167B, 209B, 228C btl ................................................ 482B btz ..................................................130 cact ............................................. 186C cad .............................................. 806B Caki ............................................. 412A cana ............................................ 298A Caps............................................ 338B cas..................................................119 Ccap...............................................142 Cdc42.......................................... 173B CG10260 ..................................... 530B CG10627 ..................................... 205A CG11148 ..................................... 687C CG11825 ..................................... 428B CG11857 ..................................... 188B CG12026 ..................................... 501C CG12264 ..................................... 438C CG13442 ..................................... 547A CG14709 ..................................... 573C CG15738 ..................................... 407B CG17689 ..........................................53 CG17734 ..................................... 428B CG18437 ..................................... 592A CG18445 ..................................... 230B CG18811 ..................................... 250A CG1950 ....................................... 546C Cg25C ......................................... 494B CG30122 ..................................... 317B CG31048 ..................................... 613A CG31864 ..................................... 438C CG32372 ..................................... 500B CG3883 ............................................53 CG4701 ....................................... 549C CG4960 ....................................... 428B CG5073 ..........................................113 CG5932 ....................................... 698B CG7172 ....................................... 333C CG7447 ....................................... 501C

CG7492 ....................................... 431B CG8177 ....................................... 239B CG8331 ....................................... 428B CG8443 ....................................... 520A CG9139 ....................................... 312C CG9866 ............................................53 Chc...................................................29 Chd1............................................ 358A chico ........................................... 233B chinmo.............................................96 chm ............................................. 343A ci.....................................................109 cic................................56, 232A, 732C Clc ....................................................29 Clic .............................................. 167B cmet ............................................ 298A cnn .................................................123 coilin .................................781A, 786C cora ............................................. 223A Corp ............................................ 279C cos .............................................. 272B Crag ............................................ 405C crb .............................. 64, 158B, 280A, 311B, 486C CrebA.......................................... 241A CrebB-17A .................................. 380B Crk............................................... 226A Csk .............................................. 286A ct ................................................. 671B CtBP.................................. 243C, 571A Ctr1A........................................... 395B cul-3 .................................................27 CycA ........................................... 335B CycJ ............................................ 522C Cyp12d1-d .................................. 459C Cyp12d1-p .................................. 459C Cyp6g1........................................ 459C da .....................................................44 dac .......................................... 9, 536B Dad.............................................. 743B dally ............................................ 182B dco .............................................. 302B Dcp-1.......................264C, 265A, 269B Dcr-2 ................................................88 Ddc.............................................. 454A desat1 ..............................................95 Dg................................................ 308B

FLYBASE GENETIC INDEX TO ABSTRACTS Dhc64C ............................................92 dia ......................................... 65, 409A disp ............................................. 182B dl ................ 11, 56, 186C, 660C, 766A Dl ................................................. 739A dlg1 ............................................. 311B Dll ............................................ 9, 536B dlp ............................................... 182B DLP ............................................. 278B dm ..........................282C, 283A, 722B, 727A, 728B, 764B Dmn..................................................70 DNApol-D .................................... 335B Doa.............................................. 227B doc .............................................. 189C dock .................................. 226A, 233B dome ........................................... 286A DopEcR....................................... 594C dor............................................... 262A dp ................................................ 787A Dp................................................ 286A dpp .................109, 176B, 383B, 424A, 500B, 658A, 743B Dpt............................................... 221B Dr......................................................74 Dref ..................................................66 Drip ............................................. 464B drpr ............................................. 261C ds .............................. 107, 159C, 161B Dscam............................... 614B, 829A dsx .............................. 74, 540C, 541A dup .................................... 256A, 257B dve ...................................................57 Dyrk3........................................... 338B Dys .................................................116 E(bx)............................................ 795C e(r)............................................... 744C E(spl)........................................... 414C E(tc)............................................. 353B E(z) .............................................. 300C E2f ............................................... 286A EcR.........................229A, 269B, 521B, 582C, 594C ed .....................................................28 Edem2......................................... 394A eff ................................................ 568A Egfr ............................ 55, 227B, 657C, 662B, 766A egr ....................................................63 eIF4AIII...........................................130 Eip75B ........................................ 714C elgi .............................................. 524B emc ..................................................44 en ............................... 43, 321C, 383B, 424A, 763A endos .......................................... 524B ERR ..................................................20 esc............................................... 300C escl....................................300C, 438C eve......................................59, 90, 111 ex................................. 64, 302B, 311B exd .............................................. 763A ey.............................374B, 667A, 671B eya............................................... 667A eyg .............................................. 686B

faf ................................................ 658A fat2 ...................................................68 fbl .....................................................94 fd3F ............................................. 641B fj .......................................... 107, 161B FKBP59....................................... 395B fln ................................................ 741C flr ................................................. 379A Fmrf................................... 635B, 724A fng ..................................... 414C, 805A foxo ............................................. 652A fra ......................................305B, 627C fru........................ 96, 141, 582C, 583A fry ................................................ 197B fs(1)h........................................... 650B Fs(2)Ket ...................................... 247A ft ................................ 107, 161B, 302B ftz .....................................................59 ftz-f1 ..................................269B, 714C futsch.......................................... 387C fwd .............................................. 285C fz.................................................. 159C gbb .............................................. 635B GckIII..............................................113 Gga.............................................. 185B giac ..................................................70 Gint3 ........................................... 184A Gl......................................................92 Gld2............................................. 551B glec ............................................. 630C Gmd ............................................ 805A Gprk2 .................................................6 GRHR .......................................... 380B grk ..................................... 662B, 782B gro................................... 55, 56, 232A grp............................................... 249C gt ................................................. 742A Gug ................................................107 Gyc-89Da .................................... 606C Gyc-89Db.................................... 606C Gyc88E ....................................... 606C gypsy .......................................... 781A h ........................................ 416B, 739A halo ............................................. 190A hb ................................................ 742A hd ................................................ 335B Hdc.............................................. 600C her ....................................................46 hh ....................... 43, 109, 182B, 272B, 424A, 684C Hira.............................................. 316A His2A:CG31618.......................... 225C His2Av ..............................225C, 330C His2B:CG17949.......................... 225C HLHmG ........................................ 765C hobo............................................ 436A hobo\T......................................... 436A hop ........................................ 98, 571A Hop........................................ 87, 283A HP1c............................................ 315C hpo .............................. 65, 268A, 311B hppy ............................................ 295A Hr4............................................... 694A Hr51............................................. 612C Hr96................................... 698B, 701B

103 Hrb98DE ..................................... 791B Hsf.....................................713B, 717C Hsp60.......................................... 386B Hsp83.................................... 87, 707B HsrW .................................................24 hth ........................................... 9, 763A htl .....................................................91 HtrA2........................................... 274A ial................................................. 298A Iap2 ............................................. 568A Ice............................264C, 268A, 269B ics................................................ 171C if .....................................................112 iHog............................................. 182B Ilk................................................. 170B imd .............................................. 568A ind ......................................... 55, 766A Ino80 ........................................... 270C InR.....................................233B, 702C Irbp.............................................. 456C ird1 .............................................. 222C Iswi.............................................. 795C Jra ............................................... 508A Kdm4A ........................................ 341B Kdm4B ........................................ 769A kel.......................................... 27, 247A ken .............................................. 571A Khc.............................................. 190A king-tubby .......................................95 kis................................................ 376A klar ............. 70, 71, 190A, 192C, 225C Klp10A ........................................ 297C Klp3A .......................................... 298A Klp59C ........................................ 297C Klp59D ........................................ 297C Klp61F......................................... 298A kn ................................................ 424A kni ............................................... 742A koi ....................................................71 Kr................................................. 742A Krn .....................................................9 krz ........................................... 6, 553A l(2)gl ............................ 63, 281B, 311B l(3)DTS3 ...................................... 594C Lag1 .................................................21 LamC..............................................115 lds ............................................... 474C Lhr............................................... 334A Lig4 ............................................. 252C Lim1 ...................................................9 lmd .............................................. 235A lok ............................................... 249C lolal ............................................. 535A lost .............................................. 785B lqf ................................................ 214A Lsd-2 .................................190A, 225C lsn ............................................... 181A lz............................................ 74, 643A m4 ............................................... 414C Mad ...................................635B, 795C mago ..............................................130 MAPk-Ak2........................................23 mats ............................................ 268A mbmB ............................................144 Mbs ............................................. 526A

104 Mcm10 ........................................ 336C Med ............................................. 658A Mef2 .................................. 715A, 718A Mer ...................................................73 Mio ...................................................95 Mipp1 .......................................... 481A mirr.............................................. 657C Mlp84B...........................................114 Mmp1 .......................................... 209B Mmp2 .......................................... 209B mmy ............................................ 176B mnd ............................................. 727A Moe ................................................113 mp ............................................... 523A Mpk2 ................................................22 ms(2)1400 ................................... 548B Msp-300 .....................................70, 71 Mst77F ........................................ 544A Mst77F-9Y1................................ 544A Mst77F-9Y2................................ 544A Mst77F-9Y3................................ 544A mt:CoI ......................................... 450C mt:CoII ........................................ 450C mTerf3......................................... 762C mth ....................................702C, 705C mts .............................................. 157A mu2 ............................................. 352A mus308 .............................252C, 330C mus309 ............................. 251B, 335B Mvl.....................................483C, 585C mwh ............................................ 379A Myb ................................... 288C, 721A mys ................ 112, 198C, 489C, 496A mA ............................................... 414C N ...................9, 98, 188B, 211A, 272B, 414C, 521B, 640A, 653B, 739A, 765C, 805A na ...................................... 591C, 592A nAcRA-30D ....................... 589A, 590B nAcRA-96Aa ............................... 589A nAcRB-96A ................................. 589A Nc ................. 264C, 268A, 269B, 279C nct ............................................... 414C nerfin-1 ............................... 119, 738C nes .............................................. 230B NetA ............................................ 627C NetB ............................................ 627C Nf1............................................... 596B NiPp1 ...............................................18 nmd ............................................. 549C Nmnat ............................... 626B, 713B nos ............................ 102, 634A, 785B Nrg .............................................. 223A Nrx-IV .......................................... 223A nub ..............9, 119, 572B, 656B, 745A numb........................................... 653B O-fut1 .......................................... 414C odd .....................................................9 opa ...................................................59 Optix ........................................... 722B Or33b .......................................... 611B Or59a .......................................... 611B Or83b .............................................143 Orc1 ............................................ 335B ord....................................................85

FLYBASE GENETIC INDEX TO ABSTRACTS os ................................ 98, 286A, 656B osk ..........................634A, 783C, 785B ovo ...................................................18 P-element ................................... 445A p38b ...........................................22, 23 p53 .............................................. 279C pain ................................................143 Pak ...................................................73 pan ....................................242B, 243C par-6...................................................7 Parg............................................. 791B Parp............................................. 216C pav .....................................................4 pburs..............................................142 Pc .....................................................85 Pcf11 ........................................... 769A pck .............................................. 492C pdm2 ................................... 119, 745A Pen ...................................... 144, 247A Pfk ....................................................20 phl ............................................... 657C Pi3K59F ............................ 222C, 262A piwi.............................................37, 87 pk ......................................159C, 375C Pkd2 ............................................ 410B polo ................................... 288C, 523A Poxn ............................................ 618C PpV.............................................. 259A Prat2............................................ 706A Psc ........................................ 85, 356B psq .............................................. 535A ptc ....................................... 109, 684C Ptp52F......................................... 229A Ptp61F......................................... 571A Ptth...................................................63 puc .............................................. 208A pum ............................................. 775A pxt ............................................... 531C R .................................................. 157A r2d2 ..................................................88 Rab11.......................................... 201C Rab14.............................................149 Rab5.................................................73 Rab6............................................ 662B Rac1 ........................158B, 625A, 826A Ras85D .................. 374B, 448A, 657C Rassf........................................... 311B raw .............................................. 508A Rbf............................................... 286A Rfx............................................... 633C rhea ........................ 198C, 489C, 490A rho...........................421A, 630C, 637A Rho1............................................ 625A rl .................... 55, 56, 130, 232A, 374B robo............................................. 491B roX1............................................. 758B roX2............................................. 758B Rpd3............................................ 583A RpL10Ab..................................... 532A RpL22.......................................... 216C Rpn12R ....................................... 546C rpr.............................. 138, 279C, 652A Rpt3R .......................................... 546C Rpt4R .......................................... 546C rumi............................................. 640A

rump............................................ 785B run..............................................43, 59 rut................................................ 594C S .................................................. 157A salm ............................................ 157A sav..................................... 268A, 311B sax............................................... 635B scarface ...................................... 208A scb .............................................. 498C Sce ...................................................85 Scr............................................... 673A scrib ............................96, 311B, 486C sd ................................................ 268A Sdc .............................................. 491B sec15........................................... 201C sec31........................................... 622A sens ............................................ 806B Sep2 ............................................ 428B Sep5 ............................................ 428B shf ............................................... 182B shg ........................................ 73, 791B shi ....................................................73 sim .............................................. 630C sima ............................................ 713B sinu ............................................. 492C sip3 ............................................. 394A Sir2...................................................17 sli.......................................491B, 498C slp1 ....................................... 59, 763A slpr .............................................. 712A sls...................................................114 Smc5 ........................................... 330C smg ............................................. 773B Smg1........................................... 779B Smg6........................................... 779B Smn..................................................91 smo ....................................................6 sn ................................................ 378C sna ...................................................11 SNCF........................................... 190A sNPF ........................................... 597C sns .................................... 173B, 226A so ...................................... 667A, 671B Sod....................................158B, 369C Sod2.................................................22 SP1070........................................ 213C spas ............................................ 668B spg .............................................. 613A spi ............................................... 630C spn-A ................................ 330C, 335B SPR ............................................. 468C sqh ...................................... 106, 527B sr ................................................. 649A SRm160 ...................................... 227B Ssrp............................................. 335B Stat92E ................ 98, 99, 283A, 286A, 339C, 571A, 656B stck ...................................170B, 171C stumps.............................................91 Su(dx) ......................................... 414C Su(H) ..................................... 11, 630C su(Hw)......................................... 516C Su(var)2-10 ................................. 656B Su(var)205 ...... 88, 315C, 330C, 334A, 335B, 337A, 338B, 583A

FLYBASE GENETIC INDEX TO ABSTRACTS Su(var)3-9 ................... 88, 330C, 337A Su(z)12........................................ 300C Su(z)2.......................................... 356B SuUR................................. 332B, 335B svp .............................................. 746B sw................................................ 190A Sxl ..........................................102, 129 Syx1A.......................................... 662B tara .............................................. 650B tau ............................................... 387C Tbp .............................................. 392B TBPH........................................... 390C tefu .............................................. 398B Tel................................................ 353B Tg ...................................................154 th ............................265A, 268A, 272B, 273C, 394A Thor...................................300C, 702C Tip60 ........................................... 345C tkv ............................................... 635B Tl ................................................. 186C Top2 ............................................ 323B Tor ......................................... 66, 800B Tpi ............................................... 416B TpnC4 ......................................... 741C TpnC41C..................................... 733A tra ................................................ 539B

trc ................................................ 197B trio..................................... 237C, 625A Trl ................................................ 535A TrpA1 .......................................... 593B tsu ..................................................130 ttk ........................... 528C, 643A, 765C tum .....................................................4 twi.....................................................11 twin ................................................129 tws............................................... 403A Ubx.............................................. 789C Uev1A ......................................... 568A unc-5 ........................................... 627C Unc-89......................................... 605B unc79 .......................................... 592A upd3 ............................................ 196A Upf1................................... 778A, 779B Upf2................................... 778A, 779B Uro .................................................151 usp .............................................. 521B Utx....................................................84 verm ............................................ 486C vfl ...................................... 630C, 730A Vha100-1..................................... 191B vkg .................................... 494B, 523A Vps16B ..........................................150 Vps25 .......................................... 181A

105 Vps36 .......................................... 181A Vrp1............................................. 173B W ............................264C, 268A, 269B, 272B, 279C WASp .......................................... 173B WDR79 ........................................ 786C wg................................4, 98, 109, 110, 240C, 243C wisp..................................................50 wit...................................... 177C, 635B wls............................................... 240C wts............................................... 268A wun ..................................... 116, 207C wun2 ........................................... 207C Wwox .......................................... 369C Xpd.............................................. 370A y.........................................423C, 771C yemA ........................................... 316A yki.......................... 64, 65, 268A, 311B yrt................................................ 486C yuri ...................................................70 z................................................... 744C zen....................................................56 zfh1 ..................................................99 zfh2 ............................................. 656B Zfrp8............................................ 560B Zpr1............................................. 487A

ANNUAL REVIEWS The Essential Resource for Genetics Research

Annual Reviews offers comprehensive, timely collections of critical, topical reviews written by acknowledged experts. Annual Reviews journals examine 40 focused disciplines within the Biomedical, Life, Physical, and Social Sciences, including Economics. Our Editorial Committees are specialists in selecting and synthesizing literature into concise, insightful review articles. As a result, Annual Reviews journals are among the most highly cited in scientific literature and are consistently ranked within the top ten of journals for their disciplines as indexed by the ISI ® Journal Citation Reports (JCR ®).

Genetics Society of America Members Save on ALL Annual Reviews Journals. Discounted Pricing available for GSA Members. Orders should be placed through the offices of the GSA.

Annual Review of Genetics Volume 43, December 2009 t
"WBJMBCMF
0OMJOF

*O
1SJOU
t
IUUQHFOFUBOOVBMSFWJFXTPSH *44/

t
*4#/

t
3FHVMBS
1FSTPOBM
$PQZ
1SJDF
WORLDWIDE 


Editor: Allan Campbell, Stanford University The Annual Review of Genetics, in publication since 1967, covers significant developments in the field of genetics. These include biochemical, behavioral, cell, and developmental genetics; evolutionary and population genetics; chromosome structure and transmission; gene function and expression; mutation and repair; genomics; immunogenetics; and other topics as related to the genetics of viruses, bacteria, fungi, plants, and animals, including humans. This journal is ideal for all geneticists, as well as those in the fields of cell and developmental biology, biochemistry, microbiology, and other life sciences.

Annual Review of Genomics and Human Genetics 7PMVNF

4FQUFNCFS


t
"WBJMBCMF
0OMJOF

*O
1SJOU
t
IUUQHFOPNBOOVBMSFWJFXTPSH JTTO
 t
*4#/

t
3FHVMBS
1FSTPOBM
$PQZ
1SJDF
WORLDWIDE 


Co-Editors: Aravinda Chakravarti, Johns Hopkins University, School of Medicine and Eric D. Green The Annual Review of Genomics and Human Genetics, in publication since 2000, covers significant developments in the field of genomics as they apply to human genetics and the human genome. The journal places particular interest in the areas of genomic technology, genome structure and function, genetic modification, human variation and population genetics, human evolution and, importantly, all aspects of human genetic disease including individualized medicine. This journal is ideal for genome scientists, human and mammalian geneticists, and physicians, as well as those in the fields of cell and developmental biology and other life sciences. Access these and all Annual Reviews journals via your institution’s subscription at www.annualreviews.org Institutional pricing and site license options available. Contact Annual Reviews for details.

ANNUAL REVIEWS t
"
/POQSPmU
4DJFOUJGJD
1VCMJTIFS
t

+PVSOBMT
t
4JODF
 TEL:

800.523.8635 (US/CAN
t
TEL: 650.493.4400 (WORLDWIDE
t
FAX: 650.424.0910 (WORLDWIDE
t
EMAIL: [email protected]

The Future of Genetics is Here

2 0 1 0

GENETICS 2010: Model Organisms to Human Biology

("

,
-
#&'#"
&&(&''& 51st Annual Drosophila Research Conference

$%

,

-
&"'#"
 Yeast Genetics and Molecular Biology Meeting

( *

,
((&'

-
"#()%

"

GENETICS SOCIETY OF AMERICA CONFERENCES and Coming in 2011… 26th Fungal Genetics Conference %

,

-
+
%#)
 #%" 52nd Annual Drosophila Research Conference %

,
$%

-
"
#
 #%" 18th International C. elegans Meeting ("
-
#&
" &
 #%" MouseGenetics 2011 ("

,

-
&"'#"


discover. understand. inform.

#%
'#"
"#%!'#" genetics-gsa.org/conferences